9w39

Structure of human 26S proteasome complexed with midnolin, 19S proteasome with Ubl bound

Method: ELECTRON MICROSCOPY
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Maltose/maltodextrin-binding periplasmic protein,Midnolin

Homo sapiens

UniProt P0AEX9

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 MALE_ECOLI
Isoform —
PDB实体 1
链与序列区间 作者链 f; PDB构建体 9–374; UniProt 27–392

Maltose/maltodextrin-binding periplasmic protein,Midnolin

Homo sapiens

UniProt Q504T8

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 MIDN_HUMAN
Isoform —
PDB实体 1
链与序列区间 作者链 f; PDB构建体 389–856; UniProt 1–468

26S proteasome regulatory subunit 8

物种未注明

UniProt P62195

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PRS8_HUMAN
Isoform —
PDB实体 2
链与序列区间 作者链 C; PDB构建体 1–406; UniProt 1–406

26S proteasome regulatory subunit 6B

物种未注明

UniProt P43686

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PRS6B_HUMAN
Isoform —
PDB实体 3
链与序列区间 作者链 D; PDB构建体 1–418; UniProt 1–418

26S proteasome non-ATPase regulatory subunit 3

物种未注明

UniProt O43242

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD3_HUMAN
Isoform —
PDB实体 4
链与序列区间 作者链 V; PDB构建体 1–534; UniProt 1–534

26S proteasome non-ATPase regulatory subunit 12

物种未注明

UniProt O00232

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSD12_HUMAN
Isoform —
PDB实体 5
链与序列区间 作者链 W; PDB构建体 1–456; UniProt 1–456

26S proteasome non-ATPase regulatory subunit 11

物种未注明

UniProt O00231

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSD11_HUMAN
Isoform —
PDB实体 6
链与序列区间 作者链 X; PDB构建体 1–422; UniProt 1–422

26S proteasome non-ATPase regulatory subunit 6

物种未注明

UniProt Q15008

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD6_HUMAN
Isoform —
PDB实体 7
链与序列区间 作者链 Y; PDB构建体 1–389; UniProt 1–389

26S proteasome non-ATPase regulatory subunit 7

物种未注明

UniProt P51665

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD7_HUMAN
Isoform —
PDB实体 8
链与序列区间 作者链 Z; PDB构建体 1–324; UniProt 1–324

26S proteasome non-ATPase regulatory subunit 13

物种未注明

UniProt Q9UNM6

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSD13_HUMAN
Isoform —
PDB实体 9
链与序列区间 作者链 a; PDB构建体 1–376; UniProt 1–376

26S proteasome non-ATPase regulatory subunit 4

物种未注明

UniProt P55036

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD4_HUMAN
Isoform —
PDB实体 10
链与序列区间 作者链 b; PDB构建体 1–377; UniProt 1–377

26S proteasome non-ATPase regulatory subunit 8

物种未注明

UniProt P48556

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD8_HUMAN
Isoform —
PDB实体 11
链与序列区间 作者链 d; PDB构建体 1–350; UniProt 1–350

26S proteasome complex subunit SEM1

物种未注明

UniProt P60896

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称 SEM1_HUMAN
Isoform —
PDB实体 12
链与序列区间 作者链 e; PDB构建体 1–70; UniProt 1–70

26S proteasome non-ATPase regulatory subunit 1

物种未注明

UniProt Q99460

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD1_HUMAN
Isoform —
PDB实体 14
链与序列区间 作者链 U; PDB构建体 1–953; UniProt 1–953

Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein

Purpureocillium lilacinum

UniProt A0A2U3DNX3

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 A0A2U3DNX3_PURLI
Isoform —
PDB实体 15
链与序列区间 作者链 c; PDB构建体 319–554; UniProt 1–236

Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein

Purpureocillium lilacinum

UniProt O00487

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSDE_HUMAN
Isoform —
PDB实体 15
链与序列区间 作者链 c; PDB构建体 1–310; UniProt 1–310

26S proteasome regulatory subunit 7

物种未注明

UniProt P35998

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PRS7_HUMAN
Isoform —
PDB实体 16
链与序列区间 作者链 A; PDB构建体 1–433; UniProt 1–433

26S proteasome regulatory subunit 4

物种未注明

UniProt P62191

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 10B × 1 (P62333) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PRS4_HUMAN
Isoform —
PDB实体 17
链与序列区间 作者链 B; PDB构建体 1–440; UniProt 1–440

26S proteasome regulatory subunit 10B

物种未注明

UniProt P62333

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 6A × 1 (P17980) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PRS10_HUMAN
Isoform —
PDB实体 18
链与序列区间 作者链 E; PDB构建体 1–389; UniProt 1–389

26S proteasome regulatory subunit 6A

物种未注明

UniProt P17980

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 信息不足 异源复合物 蛋白 19 Maltose/maltodextrin-binding periplasmic protein,Midnolin × 1 (P0AEX9,Q504T8) 26S proteasome regulatory subunit 8 × 1 (P62195) 26S proteasome regulatory subunit 6B × 1 (P43686) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit SEM1 × 1 (P60896) Substrate × 1 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) Ubiquitin C-terminal hydrolase PSMD14,Uncharacterized protein × 1 (A0A2U3DNX3,O00487) 26S proteasome regulatory subunit 7 × 1 (P35998) 26S proteasome regulatory subunit 4 × 1 (P62191) 26S proteasome regulatory subunit 10B × 1 (P62333) ADENOSINE-5'-DIPHOSPHATE × 2 ADENOSINE-5'-TRIPHOSPHATE × 4 ZINC ION × 1 MAGNESIUM ION × 3 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PRS6A_HUMAN
Isoform —
PDB实体 19
链与序列区间 作者链 F; PDB构建体 1–439; UniProt 1–439

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id9w39
沉积日期 deposition_date2025-07-29
结构标题 titleStructure of human 26S proteasome complexed with midnolin, 19S proteasome with Ubl bound
关键词 keywordsproteasome, midnolin, HYDROLASE; HYDROLASE
实验方法 methodELECTRON MICROSCOPY
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

9w39__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

9w39__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

9w39__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)66.55 Å
Rg(电子密度)65.99 Å
总 Rg66.06 Å
原子数49219
残基数6181
排除体积880880 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 9w39__assembly_1__model_1 19-meric (19) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (23)

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7. 引用文献 (1)