Current Protein Identity:A0A6A5Q270 New Search
Main Difference Dimensions in This Set
Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
7MEI Composite structure of EC+EC Deposited 2021-04-06 Assembly 1 Other combination Heteromer;Protein × 26 PDB declaration: 30-meric(30) Consistent with all polymers
Chain G 1–171(171 aa)
Chain g 1–171(171 aa)
Not recorded ZN ZINC ION × 16 MG MAGNESIUM ION × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6;20 mM HEPES PH 7.6 50 mM KoAc 5 mM DTT 2 mM MgoAc
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.54 Å
7MK9 Complex structure of trailing EC of EC+EC (trailing EC-focused) Deposited 2021-04-22 Assembly 1 Other combination Heteromer;Protein × 14 PDB declaration: heptadecameric(17) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6;20 mM HEPES PH 7.6 50 mM KoAc 5 mM DTT 2 mM MgoAc
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.54 Å
7MKA Structure of EC+EC (leading EC-focused) Deposited 2021-04-22 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: pentadecameric(15) Consistent with all polymers
Chain g 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6;20 mM HEPES PH 7.6 50 mM KoAc 5 mM DTT 2 mM MgoAc
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.54 Å
7ML0 RNA polymerase II pre-initiation complex (PIC1) Deposited 2021-04-27 Assembly 1 Protein–DNA Heteromer;Protein × 26 PDB declaration: 28-meric(28) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 17 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å
7ML1 RNA polymerase II pre-initiation complex (PIC2) Deposited 2021-04-27 Assembly 1 Protein–DNA Heteromer;Protein × 28 PDB declaration: 30-meric(30) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 19 SF4 IRON/SULFUR CLUSTER × 1 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å
7ML2 RNA polymerase II pre-initiation complex (PIC3) Deposited 2021-04-27 Assembly 1 Protein–DNA Heteromer;Protein × 28 PDB declaration: 30-meric(30) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 17 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
7ML4 RNA polymerase II initially transcribing complex (ITC) Deposited 2021-04-27 Assembly 1 Other combination Heteromer;Protein × 28 PDB declaration: 31-meric(31) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 15 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
8TUG Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (engaged state) Deposited 2023-08-16 Assembly 1 Other combination Heteromer;Protein × 13 PDB declaration: 16-meric(16) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
8TVP Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state) Deposited 2023-08-18 Assembly 1 Other combination Heteromer;Protein × 13 PDB declaration: 16-meric(16) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.70 Å
8TVS Cryo-EM structure of backtracked Pol II in complex with Rad26 Deposited 2023-08-18 Assembly 1 Other combination Heteromer;Protein × 13 PDB declaration: 16-meric(16) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.40 Å
8TVV Cryo-EM structure of backtracked Pol II Deposited 2023-08-18 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: 15-meric(15) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.70 Å
8TVW Cryo-EM structure of CPD-stalled Pol II (conformation 1) Deposited 2023-08-18 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: 15-meric(15) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.60 Å
8TVX Cryo-EM structure of CPD-stalled Pol II (Conformation 2) Deposited 2023-08-18 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: 15-meric(15) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.70 Å
8TVY Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state) Deposited 2023-08-18 Assembly 1 Other combination Heteromer;Protein × 14 PDB declaration: 17-meric(17) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
8U9R STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION USING A FREE-ELECTRON LASER Deposited 2023-09-20 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: tetradecameric(14) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 GOL GLYCEROL × 1 MG MAGNESIUM ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;289 K;10-15 % tacsimate 100mM Hepes pH 7.5
Resolution 3.34 Å R-free 0.261
8U9X STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION AT 3.0 A OF T834P MUTANT USING A FREE-ELECTRON LASER Deposited 2023-09-20 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: tetradecameric(14) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MN MANGANESE (II) ION × 3 ATP ADENOSINE-5'-TRIPHOSPHATE × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;pH 7.5;289 K;10-15 % tacsimate 100mM Hepes
Resolution 3.05 Å R-free 0.307
8UMH Consensus map of PICdeltaTFIIK form2 Deposited 2023-10-17 Assembly 1 Protein–DNA Heteromer;Protein × 28 PDB declaration: 30-meric(30) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 15 MG MAGNESIUM ION × 2 SF4 IRON/SULFUR CLUSTER × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6;20 mM HEPES PH 7.6 50 mM KOAc 5 mM DTT 2 mM MgOAc
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.10 Å
8UMI consensus map of PICdeltaTFIIK form1 Deposited 2023-10-17 Assembly 1 Protein–DNA Heteromer;Protein × 28 PDB declaration: 30-meric(30) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded SF4 IRON/SULFUR CLUSTER × 1 ZN ZINC ION × 15 MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6;20 mM HEPES PH 7.6 50 mM KOAc 5 mM DTT 2 mM MgOAc
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.70 Å
9BVT RNA Pol II - High Mn(+2) concentration Deposited 2024-05-20 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: tetradecameric(14) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 MN MANGANESE (II) ION × 2 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;277 K;Tacsimate Hepes
Resolution 3.40 Å R-free 0.249
9BW0 RNA Polymerase II - No ATP Deposited 2024-05-20 Assembly 1 Other combination Heteromer;Protein × 12 PDB declaration: tetradecameric(14) Consistent with all polymers
Chain G 1–171(171 aa)
Not recorded ZN ZINC ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 7;277 K;Tacsimate, Hepes pH 7.0
Resolution 3.51 Å R-free 0.246