Current Protein Identity：O00560
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1N99 CRYSTAL STRUCTURE OF THE PDZ TANDEM OF HUMAN SYNTENIN Deposited 2002-11-22 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
113–273（161 aa）
Fragment：PDZ Tandem
Chain B
113–273（161 aa）
Fragment：PDZ Tandem
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.6；294 K；sodium acetate, PEG4000, ammonium acetate, pH 4.6, VAPOR DIFFUSION, SITTING DROP, temperature 294K
|
Resolution 1.94 Å R-free 0.227 |
| 1NTE CRYSTAL STRUCTURE ANALYSIS OF THE SECOND PDZ DOMAIN OF SYNTENIN Deposited 2003-01-29 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
197–273（77 aa）
Fragment：PDZ 2
|
Not recorded | O OXYGEN ATOM × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；294 K；PEG 4000, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 294K
|
Resolution 1.24 Å R-free 0.153 |
| 1OBX Crystal structure of the complex of PDZ2 of syntenin with an interleukin 5 receptor alpha peptide. Deposited 2003-01-31 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
197–270（74 aa）
Fragment：PDZ2, RESIDUES 197-270
|
Not recorded | CO COBALT (II) ION × 4 SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；SITTING DROP 0.1 M HEPES, PH 7.0, 1.6 M AMMONIUM SULFATE, 20 MM COCL2, 0.2 M MGSO4 WITH MICROSEEDIN
|
Resolution 1.35 Å R-free 0.212 |
| 1OBY Crystal structure of the complex of PDZ2 of syntenin with a syndecan-4 peptide. Deposited 2003-01-31 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
197–270（74 aa）
Fragment：PDZ2, RESIDUES 197-270
Chain B
197–270（74 aa）
Fragment：PDZ2, RESIDUES 197-270
|
Not recorded | SO4 SULFATE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.8；SITTING DROP WITH 0.1 M HEPES, PH 6.8, 1.6 M AMMONIUM SULFATE, 20 MM COCL2, AND 0.2 MGSO4
|
Resolution 1.85 Å R-free 0.226 |
| 1OBZ Crystal structure of the complex of the PDZ tandem of syntenin with an interleukin 5 receptor alpha peptide. Deposited 2003-01-31 | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain A
113–273（161 aa）
Fragment：PDZ2, RESIDUES 113-273
Chain B
113–273（161 aa）
Fragment：PDZ2, RESIDUES 113-273
|
Not recorded | ACT ACETATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.6；SITTING DROP WITH 0.2 M SODIUM ACETATE, PH 4.6 28% PEG4000, 0.2 M AMMONIUM ACETATE
|
Resolution 1.70 Å R-free 0.213 |
| 1R6J Ultrahigh resolution Crystal Structure of syntenin PDZ2 Deposited 2003-10-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
197–273（77 aa）
Fragment：PDZ2 domain (residues 197-273)
|
Not recorded | CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；PEG 4000, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 295K
|
Resolution 0.73 Å R-free 0.087 |
| 1V1T Crystal structure of the PDZ tandem of human syntenin in complex with TNEYKV peptide Deposited 2004-04-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
113–273（161 aa）
Fragment：PDZ TANDEM, RESIDUES 108-273
Chain B
113–273（161 aa）
Fragment：PDZ TANDEM, RESIDUES 108-273
|
Not recorded | BEZ BENZOIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；20% PEG3350, 0.2M NH4CL, VAPOR DIFFUSION, SITTING DROP, pH 7.50
|
Resolution 1.80 Å R-free 0.229 |
| 1W9E Crystal structure of the PDZ tandem of human syntenin in complex with TNEFYF peptide Deposited 2004-10-09 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain A
113–273（161 aa）
Fragment：PDZ TANDEM, RESIDUES 113-273
Chain B
113–273（161 aa）
Fragment：PDZ TANDEM, RESIDUES 113-273
|
Not recorded | BEZ BENZOIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；20% PEG3350, 0.2M NH4CL, VAPOR DIFFUSION, SITTING DROP, pH 7.50
|
Resolution 1.56 Å R-free 0.201 |
| 1W9O Crystal structure of the PDZ tandem of human syntenin in complex with TNEYYV peptide Deposited 2004-10-15 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
113–273（161 aa）
Fragment：PDZ TANDEM, RESIDUES 113-273
|
Not recorded | BEZ BENZOIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；20% PEG3350, 0.2M NH4CL, VAPOR DIFFUSION, SITTING DROP, pH 7.50
|
Resolution 2.25 Å R-free 0.281 |
| 1W9O Crystal structure of the PDZ tandem of human syntenin in complex with TNEYYV peptide Deposited 2004-10-15 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
113–273（161 aa）
Fragment：PDZ TANDEM, RESIDUES 113-273
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；20% PEG3350, 0.2M NH4CL, VAPOR DIFFUSION, SITTING DROP, pH 7.50
|
Resolution 2.25 Å R-free 0.281 |
| 1W9Q Crystal structure of the PDZ tandem of human syntenin in complex with TNEFAF peptide Deposited 2004-10-15 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
113–273（161 aa）
Fragment：PDZ TANDEM, RESIDUES 113-273
|
Not recorded | BEZ BENZOIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；20% PEG3350, 0.2M NH4CL, VAPOR DIFFUSION, SITTING DROP, pH 7.50
|
Resolution 1.70 Å R-free 0.224 |
| 1W9Q Crystal structure of the PDZ tandem of human syntenin in complex with TNEFAF peptide Deposited 2004-10-15 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
113–273（161 aa）
Fragment：PDZ TANDEM, RESIDUES 113-273
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；20% PEG3350, 0.2M NH4CL, VAPOR DIFFUSION, SITTING DROP, pH 7.50
|
Resolution 1.70 Å R-free 0.224 |
| 1YBO Crystal structure of the PDZ tandem of human syntenin with syndecan peptide Deposited 2004-12-21 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
113–273（161 aa）
Chain B
113–273（161 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；20% PEG 3350, 0.2M NH4Cl, VAPOR DIFFUSION, SITTING DROP
|
Resolution 2.30 Å R-free 0.273 |
| 4Z33 Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2 Deposited 2015-03-30 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
111–275（165 aa）
Fragment：residues 111-275
|
Not recorded | ACT ACETATE ION × 1 GOL GLYCEROL × 2 IP2 D-MYO-INOSITOL-4,5-BISPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；0.2 M ammonium acetate, 0.1 M sodium citrate tribasic dihydrate and 32,5% (w/v) PEG 4.000
|
Resolution 2.45 Å R-free 0.239 |
| 4Z33 Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2 Deposited 2015-03-30 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
111–275（165 aa）
Fragment：residues 111-275
|
Not recorded | ACT ACETATE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；0.2 M ammonium acetate, 0.1 M sodium citrate tribasic dihydrate and 32,5% (w/v) PEG 4.000
|
Resolution 2.45 Å R-free 0.239 |
| 6R9H Crystal structure of the PDZ tandem of syntenin in complex with fragment C58 Deposited 2019-04-03 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
113–273（161 aa）
Chain C
113–273（161 aa）
|
Not recorded | PO4 PHOSPHATE ION × 3 JVK (2~{S})-2-[2-(4-chlorophenyl)sulfanylethanoylamino]-3-methyl-butanoic acid × 2 ACT ACETATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；277 K；100 mM Sodium Acetate pH 4.6, 200mM Ammonium Acetate, 22% PEG 3350
|
Resolution 2.00 Å R-free 0.246 |
| 6R9H Crystal structure of the PDZ tandem of syntenin in complex with fragment C58 Deposited 2019-04-03 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
113–273（161 aa）
Chain D
113–273（161 aa）
|
Not recorded | PO4 PHOSPHATE ION × 1 ACT ACETATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；277 K；100 mM Sodium Acetate pH 4.6, 200mM Ammonium Acetate, 22% PEG 3350
|
Resolution 2.00 Å R-free 0.246 |
| 6RLC Crystal structure of the PDZ tandem of syntenin in complex with fragment F13 Deposited 2019-05-02 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
113–273（161 aa）
Chain B
113–273（161 aa）
|
Not recorded | K7Z (2~{S})-2-[3-(4-chlorophenyl)sulfanylpropanoylamino]-3-methyl-butanoic acid × 2 ACT ACETATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；277 K；100 mM Sodium Acetate pH 4.6, 200mM Ammonium Acetate, 22% PEG 3350
|
Resolution 2.20 Å R-free 0.301 |
| 6RLC Crystal structure of the PDZ tandem of syntenin in complex with fragment F13 Deposited 2019-05-02 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
113–273（161 aa）
Chain D
113–273（161 aa）
|
Not recorded | K7Z (2~{S})-2-[3-(4-chlorophenyl)sulfanylpropanoylamino]-3-methyl-butanoic acid × 2 ACT ACETATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；277 K；100 mM Sodium Acetate pH 4.6, 200mM Ammonium Acetate, 22% PEG 3350
|
Resolution 2.20 Å R-free 0.301 |
| 7FSG SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z56772132 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.02 Å R-free 0.252 |
| 7FSG SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z56772132 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.02 Å R-free 0.252 |
| 7FSG SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z56772132 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.02 Å R-free 0.252 |
| 7FSG SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z56772132 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 3 YG9 (5R)-5-[2-(4-methoxyphenyl)ethyl]-5-methylimidazolidine-2,4-dione × 2 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.02 Å R-free 0.252 |
| 7FSH SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z32367954 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.247 |
| 7FSH SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z32367954 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.247 |
| 7FSH SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z32367954 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 UXA ~{N}-cyclopropyl-1,3-benzodioxole-5-carboxamide × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.247 |
| 7FSH SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z32367954 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 UXA ~{N}-cyclopropyl-1,3-benzodioxole-5-carboxamide × 2 GLY GLYCINE × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.247 |
| 7FSI SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z18197050 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.31 Å R-free 0.278 |
| 7FSI SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z18197050 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.31 Å R-free 0.278 |
| 7FSI SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z18197050 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 RZG methyl 4-sulfamoylbenzoate × 1 SO4 SULFATE ION × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.31 Å R-free 0.278 |
| 7FSI SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z18197050 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 RZG methyl 4-sulfamoylbenzoate × 1 SO4 SULFATE ION × 3 GLY GLYCINE × 1 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.31 Å R-free 0.278 |
| 7FSJ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z57744712 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | YEB N,N-dimethylmorpholine-4-sulfonamide × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.97 Å R-free 0.260 |
| 7FSJ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z57744712 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.97 Å R-free 0.260 |
| 7FSJ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z57744712 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.97 Å R-free 0.260 |
| 7FSJ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z57744712 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.97 Å R-free 0.260 |
| 7FSK SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1954800564 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.294 |
| 7FSK SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1954800564 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.294 |
| 7FSK SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1954800564 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 SO4 SULFATE ION × 1 NZ1 5-methoxy-1,3-benzothiazol-2-amine × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.294 |
| 7FSK SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1954800564 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 3 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.294 |
| 7FSL SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z730649594 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | NUM N-[2-(4-hydroxyphenyl)ethyl]pyridine-2-carboxamide × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.38 Å R-free 0.296 |
| 7FSL SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z730649594 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.38 Å R-free 0.296 |
| 7FSL SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z730649594 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.38 Å R-free 0.296 |
| 7FSL SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z730649594 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.38 Å R-free 0.296 |
| 7FSM SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z763030030 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | WJA N-methyl-1-(5-methyl-1,2-oxazol-3-yl)methanesulfonamide × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.10 Å R-free 0.330 |
| 7FSM SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z763030030 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.10 Å R-free 0.330 |
| 7FSM SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z763030030 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.10 Å R-free 0.330 |
| 7FSM SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z763030030 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 2 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.10 Å R-free 0.330 |
| 7FSN SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z254580486 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | YDG N,N-dimethyl-2-(1H-pyrazol-1-yl)acetamide × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.343 |
| 7FSN SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z254580486 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.343 |
| 7FSN SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z254580486 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.343 |
| 7FSN SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z254580486 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 2 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.343 |
| 7FSO SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z198195770 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.90 Å R-free 0.292 |
| 7FSO SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z198195770 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.90 Å R-free 0.292 |
| 7FSO SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z198195770 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.90 Å R-free 0.292 |
| 7FSO SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z198195770 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 2 LJA N-[3-(carbamoylamino)phenyl]acetamide × 1 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.90 Å R-free 0.292 |
| 7FSP SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1650168321 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.86 Å R-free 0.239 |
| 7FSP SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1650168321 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.86 Å R-free 0.239 |
| 7FSP SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1650168321 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.86 Å R-free 0.239 |
| 7FSP SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1650168321 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 2 VW7 N-(8-methyl-1,2,3,4-tetrahydroquinolin-5-yl)acetamide × 1 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.86 Å R-free 0.239 |
| 7FSQ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1429867185 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | VVP 4-methoxy-1H-indole × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.07 Å R-free 0.301 |
| 7FSQ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1429867185 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | VVP 4-methoxy-1H-indole × 1 EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.07 Å R-free 0.301 |
| 7FSQ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1429867185 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.07 Å R-free 0.301 |
| 7FSQ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1429867185 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 2 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.07 Å R-free 0.301 |
| 7FSR SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z54615640 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.29 Å R-free 0.277 |
| 7FSR SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z54615640 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.29 Å R-free 0.277 |
| 7FSR SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z54615640 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.29 Å R-free 0.277 |
| 7FSR SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z54615640 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 YFN N-[(3S)-3-methyl-1,1-dioxo-1lambda~6~-thiolan-3-yl]cyclopropanecarboxamide × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.29 Å R-free 0.277 |
| 7FSS SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z839706072 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.343 |
| 7FSS SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z839706072 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 2NU 2-(4-bromanylpyrazol-1-yl)-~{N}-cyclopropyl-~{N}-methyl-ethanamide × 1 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.343 |
| 7FSS SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z839706072 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.343 |
| 7FSS SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z839706072 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 2 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.343 |
| 7FST SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z26968795 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.98 Å R-free 0.343 |
| 7FST SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z26968795 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.98 Å R-free 0.343 |
| 7FST SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z26968795 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 Q6O N-(4-chloro-2,5-dimethoxyphenyl)acetamide × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.98 Å R-free 0.343 |
| 7FST SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z26968795 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 1 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.98 Å R-free 0.343 |
| 7FSU SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z729726784 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.97 Å R-free 0.248 |
| 7FSU SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z729726784 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.97 Å R-free 0.248 |
| 7FSU SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z729726784 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.97 Å R-free 0.248 |
| 7FSU SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z729726784 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 YDU 2-cyclopentyl-N-(3-methyl-1,2,4-oxadiazol-5-yl)acetamide × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.97 Å R-free 0.248 |
| 7FSV SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1454310449 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | UQS N-[(2-fluorophenyl)methyl]-1H-pyrazol-4-amine × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.25 Å R-free 0.288 |
| 7FSV SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1454310449 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | UQS N-[(2-fluorophenyl)methyl]-1H-pyrazol-4-amine × 1 EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.25 Å R-free 0.288 |
| 7FSV SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1454310449 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | UQS N-[(2-fluorophenyl)methyl]-1H-pyrazol-4-amine × 1 EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.25 Å R-free 0.288 |
| 7FSV SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1454310449 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | UQS N-[(2-fluorophenyl)methyl]-1H-pyrazol-4-amine × 1 EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 1 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.25 Å R-free 0.288 |
| 7FSW SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z169675004 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | YDX N-(1-methyl-1H-pyrazol-3-yl)-2-(1H-pyrazol-1-yl)acetamide × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.14 Å R-free 0.325 |
| 7FSW SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z169675004 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.14 Å R-free 0.325 |
| 7FSW SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z169675004 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.14 Å R-free 0.325 |
| 7FSW SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z169675004 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 2 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.14 Å R-free 0.325 |
| 7FSX SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1328078283 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.91 Å R-free 0.235 |
| 7FSX SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1328078283 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 I8A N-(cyclopropylmethyl)-2,2,3,3-tetramethylazetidine-1-carboxamide × 1 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.91 Å R-free 0.235 |
| 7FSX SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1328078283 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 I8A N-(cyclopropylmethyl)-2,2,3,3-tetramethylazetidine-1-carboxamide × 1 SO4 SULFATE ION × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.91 Å R-free 0.235 |
| 7FSX SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1328078283 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 SO4 SULFATE ION × 3 GLY GLYCINE × 1 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.91 Å R-free 0.235 |
| 7FSY SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1148165337 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | YG5 2-(1H-indazol-1-yl)-N,N-dimethylacetamide × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.80 Å R-free 0.304 |
| 7FSY SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1148165337 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.80 Å R-free 0.304 |
| 7FSY SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1148165337 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.80 Å R-free 0.304 |
| 7FSY SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1148165337 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 2 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.80 Å R-free 0.304 |
| 7FSZ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z3006151474 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.05 Å R-free 0.340 |
| 7FSZ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z3006151474 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.05 Å R-free 0.340 |
| 7FSZ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z3006151474 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.05 Å R-free 0.340 |
| 7FSZ SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z3006151474 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 LQ3 (5S)-5-(difluoromethoxy)pyridin-2(5H)-one × 1 SO4 SULFATE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.05 Å R-free 0.340 |
| 7FT0 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z56767614 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.45 Å R-free 0.274 |
| 7FT0 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z56767614 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.45 Å R-free 0.274 |
| 7FT0 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z56767614 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 RWP methyl 4-[(trifluoroacetyl)amino]benzoate × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.45 Å R-free 0.274 |
| 7FT0 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z56767614 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 3 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 PGE TRIETHYLENE GLYCOL × 1 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.45 Å R-free 0.274 |
| 7FT1 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z2204875953 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.256 |
| 7FT1 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z2204875953 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.256 |
| 7FT1 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z2204875953 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 Q7L (3P)-3-(2H-1,3-benzodioxol-5-yl)-1H-pyrazole × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.256 |
| 7FT1 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z2204875953 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 Q7L (3P)-3-(2H-1,3-benzodioxol-5-yl)-1H-pyrazole × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.11 Å R-free 0.256 |
| 7FT2 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z235449082 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.04 Å R-free 0.322 |
| 7FT2 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z235449082 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.04 Å R-free 0.322 |
| 7FT2 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z235449082 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 GLY GLYCINE × 1 JFS [4-(1H-benzimidazol-1-yl)phenyl]methanol × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.04 Å R-free 0.322 |
| 7FT2 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z235449082 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 JFS [4-(1H-benzimidazol-1-yl)phenyl]methanol × 1 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.04 Å R-free 0.322 |
| 7FT3 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z291279160 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.05 Å R-free 0.279 |
| 7FT3 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z291279160 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 LV4 1-[2-(trifluoromethyloxy)phenyl]thiourea × 1 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.05 Å R-free 0.279 |
| 7FT3 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z291279160 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 LV4 1-[2-(trifluoromethyloxy)phenyl]thiourea × 2 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.05 Å R-free 0.279 |
| 7FT3 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z291279160 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 LV4 1-[2-(trifluoromethyloxy)phenyl]thiourea × 1 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.05 Å R-free 0.279 |
| 7FT4 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z48847594 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | O0J N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.17 Å R-free 0.347 |
| 7FT4 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z48847594 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.17 Å R-free 0.347 |
| 7FT4 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z48847594 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.17 Å R-free 0.347 |
| 7FT4 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z48847594 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 2 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.17 Å R-free 0.347 |
| 7FT5 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with POB0093 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | YEF 4-(4-methoxyphenyl)oxane-4-carboxylic acid × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.77 Å R-free 0.299 |
| 7FT5 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with POB0093 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.77 Å R-free 0.299 |
| 7FT5 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with POB0093 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | YEF 4-(4-methoxyphenyl)oxane-4-carboxylic acid × 1 EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.77 Å R-free 0.299 |
| 7FT5 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with POB0093 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.77 Å R-free 0.299 |
| 7FT6 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with POB0008 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.85 Å R-free 0.262 |
| 7FT6 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with POB0008 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.85 Å R-free 0.262 |
| 7FT6 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with POB0008 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.85 Å R-free 0.262 |
| 7FT6 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with POB0008 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 YEK methyl 1-(methanesulfonyl)-2-methyl-D-prolinate × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.85 Å R-free 0.262 |
| 7FT7 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z57127349 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | SZB succinimide × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.78 Å R-free 0.236 |
| 7FT7 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z57127349 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | SZB succinimide × 1 EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.78 Å R-free 0.236 |
| 7FT7 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z57127349 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.78 Å R-free 0.236 |
| 7FT7 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z57127349 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | SZB succinimide × 2 EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.78 Å R-free 0.236 |
| 7FT8 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with NCL-00024671 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.291 |
| 7FT8 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with NCL-00024671 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.291 |
| 7FT8 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with NCL-00024671 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 UU1 2-(4-bromo-1H-pyrazol-1-yl)ethan-1-ol × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.291 |
| 7FT8 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with NCL-00024671 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 UU1 2-(4-bromo-1H-pyrazol-1-yl)ethan-1-ol × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.40 Å R-free 0.291 |
| 7FT9 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z45636695 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.77 Å R-free 0.247 |
| 7FT9 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z45636695 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.77 Å R-free 0.247 |
| 7FT9 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z45636695 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 4MB 4-[(METHYLSULFONYL)AMINO]BENZOIC ACID × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.77 Å R-free 0.247 |
| 7FT9 SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z45636695 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 3 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.77 Å R-free 0.247 |
| 7FTA SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z228589380 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.03 Å R-free 0.330 |
| 7FTA SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z228589380 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.03 Å R-free 0.330 |
| 7FTA SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z228589380 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 YER 3-[(pyrimidin-2-yl)amino]benzoic acid × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.03 Å R-free 0.330 |
| 7FTA SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z228589380 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 YER 3-[(pyrimidin-2-yl)amino]benzoic acid × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.03 Å R-free 0.330 |
| 7FTB SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1198269757 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.22 Å R-free 0.328 |
| 7FTB SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1198269757 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 YEZ [1]benzofuro[2,3-d]pyridazin-4(3H)-one × 1 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.22 Å R-free 0.328 |
| 7FTB SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1198269757 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.22 Å R-free 0.328 |
| 7FTB SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1198269757 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 2.22 Å R-free 0.328 |
| 7FTC SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1509711879 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.87 Å R-free 0.256 |
| 7FTC SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1509711879 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.87 Å R-free 0.256 |
| 7FTC SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1509711879 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 YFR 6-bromo-7-hydroxy-2,2-dimethyl-2H,4H-1,3-benzodioxin-4-one × 1 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.87 Å R-free 0.256 |
| 7FTC SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1509711879 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 YFR 6-bromo-7-hydroxy-2,2-dimethyl-2H,4H-1,3-benzodioxin-4-one × 2 GLY GLYCINE × 1 SO4 SULFATE ION × 2 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.87 Å R-free 0.256 |
| 7FTD SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z27782662 Deposited 2023-01-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | YG0 N-phenylcyclopropanecarboxamide × 1 EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.80 Å R-free 0.359 |
| 7FTD SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z27782662 Deposited 2023-01-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.80 Å R-free 0.359 |
| 7FTD SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z27782662 Deposited 2023-01-24 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 GLY GLYCINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.80 Å R-free 0.359 |
| 7FTD SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z27782662 Deposited 2023-01-24 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 SO4 SULFATE ION × 2 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；100 mM Morpheus amino acids, 100 mM Morpheus buffer system 1, 43% Morpheus precipitant mix 3
|
Resolution 1.80 Å R-free 0.359 |
| 8AAI Crystal structure of the PDZ tandem of syntenin in complex with fragment E5 Deposited 2022-07-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
113–273（161 aa）
Chain C
113–273（161 aa）
|
Not recorded | LKV (2~{S})-2-[[(2~{S})-3-methyl-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)butanoyl]amino]propanoic acid × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；297 K；100mM Sodium Acetate
200mM Ammonium acetate
20% PEG 3350
|
Resolution 2.76 Å R-free 0.317 |
| 8AAI Crystal structure of the PDZ tandem of syntenin in complex with fragment E5 Deposited 2022-07-01 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
113–273（161 aa）
Chain D
113–273（161 aa）
|
Not recorded | LKV (2~{S})-2-[[(2~{S})-3-methyl-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)butanoyl]amino]propanoic acid × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；297 K；100mM Sodium Acetate
200mM Ammonium acetate
20% PEG 3350
|
Resolution 2.76 Å R-free 0.317 |
| 8AAK Crystal structure of the PDZ tandem of syntenin in complex with compound 29 Deposited 2022-07-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
113–273（161 aa）
Chain B
113–273（161 aa）
|
Not recorded | LL6 (2~{S})-2-[[(2~{S})-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)-3-phenyl-propanoyl]amino]propanoic acid × 2 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；297 K；100mM sodium acetate
200mM ammonium acetate
20% PEG3350
|
Resolution 2.55 Å R-free 0.282 |
| 8AAO Crystal structure of the PDZ tandem of syntenin in complex with compound 95 Deposited 2022-07-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
113–273（161 aa）
Chain B
113–273（161 aa）
|
Not recorded | LN2 (2~{S})-2-[[(2~{S})-3-[4-(5-ethanoyl-2-fluoranyl-phenyl)phenyl]-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)propanoyl]amino]propanoic acid × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；100mM sodium acetate
200mM ammonium acetate
20% PEG 3350
|
Resolution 2.47 Å R-free 0.279 |
| 8AAP Crystal structure of the PDZ tandem of syntenin in complex with compound SYNTi Deposited 2022-07-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
113–273（161 aa）
Chain B
113–273（161 aa）
|
Not recorded | LLV (2S)-2-[[(2S)-2-(6-bromanyl-3-oxidanylidene-1H-isoindol-2-yl)-3-[4-(5-ethanoyl-2-fluoranyl-phenyl)phenyl]propanoyl]amino]propanoic acid × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；100mM sodium acetate
200mM ammonium acetate
20% PEG 3350
|
Resolution 2.17 Å R-free 0.256 |
| 8BLU The PDZ domains of human SDCBP Deposited 2022-11-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.7；293 K；50 mM imidazole, 50 mM MES, 100 mM Morpheus amino acid mix, 8.3% PEG 8000, 16.6% Ethylene glycol
|
Resolution 1.50 Å R-free 0.223 |
| 8BLU The PDZ domains of human SDCBP Deposited 2022-11-10 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 GOL GLYCEROL × 1 DGL D-GLUTAMIC ACID × 1 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.7；293 K；50 mM imidazole, 50 mM MES, 100 mM Morpheus amino acid mix, 8.3% PEG 8000, 16.6% Ethylene glycol
|
Resolution 1.50 Å R-free 0.223 |
| 8BLU The PDZ domains of human SDCBP Deposited 2022-11-10 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 GLY GLYCINE × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.7；293 K；50 mM imidazole, 50 mM MES, 100 mM Morpheus amino acid mix, 8.3% PEG 8000, 16.6% Ethylene glycol
|
Resolution 1.50 Å R-free 0.223 |
| 8BLU The PDZ domains of human SDCBP Deposited 2022-11-10 | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
106–298（193 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 1 GOL GLYCEROL × 1 DGL D-GLUTAMIC ACID × 1 GLY GLYCINE × 1 ALA ALANINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.7；293 K；50 mM imidazole, 50 mM MES, 100 mM Morpheus amino acid mix, 8.3% PEG 8000, 16.6% Ethylene glycol
|
Resolution 1.50 Å R-free 0.223 |
| 8BLV The PDZ domains of human SDCBP with a bound SDC4 C-terminal peptide Deposited 2022-11-10 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
106–298（193 aa）
|
Not recorded | SO4 SULFATE ION × 2 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.3；293 K；200 mM sodium sulphate, 100 mM bis-tris-propane, 10% ethylene glycol, 20% PEG 3350
|
Resolution 1.50 Å R-free 0.222 |
| 8BLV The PDZ domains of human SDCBP with a bound SDC4 C-terminal peptide Deposited 2022-11-10 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
106–298（193 aa）
|
Not recorded | SO4 SULFATE ION × 1 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.3；293 K；200 mM sodium sulphate, 100 mM bis-tris-propane, 10% ethylene glycol, 20% PEG 3350
|
Resolution 1.50 Å R-free 0.222 |
| 8HCK NMR fragment-based screening against the two PDZ do-mains of MDA-9 Deposited 2022-11-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
113–191（79 aa）
|
Not recorded | P1Z 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE × 2 SO4 SULFATE ION × 4 GOL GLYCEROL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293.15 K；e.g.Cobalt chlonde hexahydrate,
MES monohydrate, Ammouium sulfate.
|
Resolution 2.00 Å R-free 0.264 |
| 9V90 Crystal structure of the PDZ tandem of syntenin in complex with PDZ2 inhibitor Deposited 2025-05-30 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
111–273（163 aa）
|
Not recorded | LKV (2~{S})-2-[[(2~{S})-3-methyl-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)butanoyl]amino]propanoic acid × 1 ACT ACETATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.6；293 K；0.4 M ammonium acetate, 0.1 M Sodium acetate, 20% PEG 3,350
|
Resolution 1.40 Å R-free 0.220 |
| 9V90 Crystal structure of the PDZ tandem of syntenin in complex with PDZ2 inhibitor Deposited 2025-05-30 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
111–273（163 aa）
|
Not recorded | LKV (2~{S})-2-[[(2~{S})-3-methyl-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)butanoyl]amino]propanoic acid × 1 ACT ACETATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.6；293 K；0.4 M ammonium acetate, 0.1 M Sodium acetate, 20% PEG 3,350
|
Resolution 1.40 Å R-free 0.220 |
| 9VA6 Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-02 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；293 K；0.2 M Sodium chloride, 0.1 M HEPES, 25% PEG 3,350
|
Resolution 2.09 Å R-free 0.336 |
| 9VA6 Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-02 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；293 K；0.2 M Sodium chloride, 0.1 M HEPES, 25% PEG 3,350
|
Resolution 2.09 Å R-free 0.336 |
| 9VA9 Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.2 M Sodium formate, 20% PEG 3,350
|
Resolution 1.81 Å R-free 0.299 |
| 9VA9 Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.2 M Sodium formate, 20% PEG 3,350
|
Resolution 1.81 Å R-free 0.299 |
| 9VAC Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.6；293 K；0.2 M ammonium acetate, 0.1 M Sodium citrate tribasic dihydrate, 30% PEG 3,350
|
Resolution 2.02 Å R-free 0.274 |
| 9VAC Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.6；293 K；0.2 M ammonium acetate, 0.1 M Sodium citrate tribasic dihydrate, 30% PEG 3,350
|
Resolution 2.02 Å R-free 0.274 |
| 9VAD Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；0.2 M Lithium sulfate monohydrate, 0.1 M Tris, 25% PEG 3,350
|
Resolution 2.05 Å R-free 0.294 |
| 9VAD Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；0.2 M Lithium sulfate monohydrate, 0.1 M Tris, 25% PEG 3,350
|
Resolution 2.05 Å R-free 0.294 |
| 9VAF Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；293 K；0.2 M sodium chloride, 0.1 M BIS-TRIS, 25% PEG 3,350
|
Resolution 1.85 Å R-free 0.321 |
| 9VAF Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；293 K；0.2 M sodium chloride, 0.1 M BIS-TRIS, 25% PEG 3,350
|
Resolution 1.85 Å R-free 0.321 |
| 9VAI Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.6；293 K；0.2 M ammonium acetate, 0.1 M sodium acetate trihydrate, 30% PEG 4,000
|
Resolution 1.86 Å R-free 0.297 |
| 9VAI Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.6；293 K；0.2 M ammonium acetate, 0.1 M sodium acetate trihydrate, 30% PEG 4,000
|
Resolution 1.86 Å R-free 0.297 |
| 9VAL Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；0.2 M sodium chloride, 0.1 M Tris, 25% PEG 3,350
|
Resolution 2.15 Å R-free 0.361 |
| 9VAL Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-03 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；0.2 M sodium chloride, 0.1 M Tris, 25% PEG 3,350
|
Resolution 2.15 Å R-free 0.361 |
| 9VB9 Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-04 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；293 K；0.1 M BIS-TRIS, 25% PEG 3,350
|
Resolution 2.31 Å R-free 0.313 |
| 9VB9 Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-04 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；293 K；0.1 M BIS-TRIS, 25% PEG 3,350
|
Resolution 2.31 Å R-free 0.313 |
| 9VBB Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-04 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；293 K；0.2 M ammonium acetate, 0.1 M BIS-TRIS, 25% PEG 3,350
|
Resolution 1.90 Å R-free 0.302 |
| 9VBB Crystal structure of the PDZ tandem of syntenin Deposited 2025-06-04 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
111–276（166 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；293 K；0.2 M ammonium acetate, 0.1 M BIS-TRIS, 25% PEG 3,350
|
Resolution 1.90 Å R-free 0.302 |