Current Protein Identity：P07992
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1Z00 Solution structure of the C-terminal domain of ERCC1 complexed with the C-terminal domain of XPF Deposited 2005-03-01 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
220–297（78 aa）
Fragment：C-TERMINAL DOMAIN
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；295.5 K；Ionic strength (raw mmCIF value) 50mM phosphate, 100mM NaCl；Pressure 1
NMR sample composition
1.5mM ERCC1-XPF U-15N,13C; 50mM phosphate buffer NA: 92% H2O, 8% D2O | 92% H2O, 8% D2O
NMR sample composition
1mM ERCC1-XPF U-15N; 50mM phosphate buffer NA: 92% H2O, 8% D2O | 92% H2O, 8% D2O
|
Resolution not provided |
| 2A1I Crystal Structure of the Central Domain of Human ERCC1 Deposited 2005-06-20 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
96–227（132 aa）
Fragment：CENTRAL DOMAIN
|
Not recorded | HG MERCURY (II) ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；MES, PEG 5000 MME, GLYCEROL, pH 6.5, VAPOR DIFFUSION, SITTING DROP,temperature 295K
|
Resolution 1.90 Å R-free 0.248 |
| 2A1J Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1 Deposited 2005-06-20 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
220–296（77 aa）
Fragment：C-terminal domain
|
Not recorded | HG MERCURY (II) ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；295 K；Sodium Citrate, Ammonium Sulfate, Sodium Chloride, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.70 Å R-free 0.275 |
| 2A1J Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1 Deposited 2005-06-20 | Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
220–296（77 aa）
Fragment：C-terminal domain
|
Not recorded | HG MERCURY (II) ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；295 K；Sodium Citrate, Ammonium Sulfate, Sodium Chloride, pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.70 Å R-free 0.275 |
| 2JNW Solution structure of a ERCC1-XPA heterodimer Deposited 2007-02-07 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
96–214（119 aa）
Fragment：Central domain, residues 96-214
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7.2；295 K；Ionic strength (raw mmCIF value) 0.05；Pressure ambient
NMR sample composition
0.25 mM [U-100% 13C; U-100% 15N] ERCC1, 20 mM Tris-HCl pH 7.2, 50 mM NaCl, 2 mM beta-mercaptoethanol, 0.1 mM EDTA, 90% H2O, 10% D2O | 90% H2O/10% D2O
NMR sample composition
0.25 mM [U-100% 15N, 100% 2H] ERCC1, 20 mM Tris-HCl pH 7.2, 50 mM NaCl, 2 mM beta-mercaptoethanol, 0.1 mM EDTA, 90% H2O, 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2JPD Solution structure of the ERCC1 central domain Deposited 2007-05-06 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
96–219（124 aa）
Fragment：residues 96-219
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 5.5；290 K；Ionic strength (raw mmCIF value) 0.2；Pressure ambient
NMR sample composition
50 mM sodium phosphate, 100 mM sodium chloride, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2MUT Solution structure of the F231L mutant ERCC1-XPF dimerization region Deposited 2014-09-17 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
220–297（78 aa）
Fragment：UNP residues 220-297
|
Mutation：F231L | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；290 K；Ionic strength (raw mmCIF value) 250；Pressure ambient
NMR sample composition
0.4 mM [U-100% 13C; U-100% 15N] protein_1, 0.4 mM [U-100% 13C; U-100% 15N] protein_2, 8 % D2O, 50 mM sodium phosphate, 100 mM sodium chloride, 92% H2O/8% D2O | 92% H2O/8% D2O
|
Resolution not provided |
| 6SXA XPF-ERCC1 Cryo-EM Structure, Apo-form Deposited 2019-09-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain G
1–297（297 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.8；20 mM HEPES pH 7.8, 150 mM NaCl, 1 mM TCEP, 0.01% CHAPS
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å |
| 6SXB XPF-ERCC1 Cryo-EM Structure, DNA-Bound form Deposited 2019-09-25 | Assembly 1 Protein–DNA Heteromer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers |
Chain G
1–297（297 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.8；20 mM HEPES pH 7.8, 150 mM NaCl, 1 mM TCEP, 0.01% CHAPS
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 7.90 Å |
| 9PCP NER dual incision complex - NoG Deposited 2025-06-28 | Assembly 1 Protein–DNA Heteromer；Protein × 13 PDB declaration: 15-meric（15） Consistent with all polymers |
Chain R
1–297（297 aa）
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 1 ZN ZINC ION × 6 CA CALCIUM ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.30 Å |
| 9PD3 NER dual incision complex - DuIS Deposited 2025-06-30 | Assembly 1 Protein–DNA Heteromer；Protein × 15 PDB declaration: 17-meric（17） Consistent with all polymers |
Chain R
1–295（295 aa）
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 1 ZN ZINC ION × 7 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 9PD4 NER dual incision complex - DuIM Deposited 2025-06-30 | Assembly 1 Protein–DNA Heteromer；Protein × 14 PDB declaration: hexadecameric（16） Consistent with all polymers |
Chain R
1–295（295 aa）
|
Not recorded | SF4 IRON/SULFUR CLUSTER × 1 ZN ZINC ION × 7 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å |
| 9QEC Cryo-EM structure of the XPF-ERCC1-XPA complex Deposited 2025-03-08 | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain B
1–297（297 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å |
| 9QED Cryo-EM structure of the XPF-ERCC1-SLX4(330-555)-SLX4IP complex Deposited 2025-03-09 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
1–297（297 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 9QEE Cryo-EM structure of a DNA-bound XPF-ERCC1-SLX4(330-555)-SLX4IP complex Deposited 2025-03-09 | Assembly 1 Protein–DNA Heteromer；Protein × 4 PDB declaration: hexameric（6） Consistent with all polymers |
Chain B
1–297（297 aa）
|
Not recorded | MN MANGANESE (II) ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.9
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å |