← Back to search

Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P13423 New Search
29PDB entries
43Biological assembly
171chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1ACC ANTHRAX PROTECTIVE ANTIGEN Deposited 1997-02-05 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa）
Not recorded CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6；277 K；PROTEIN WAS CRYSTALLIZED FROM 12-18% PEG 8K AND 50 MM CITRATE, PH 6.0 AT 4 DEGREES C. CRYSTAL FORM ""2"" (NEEDLE-LIKE CRYSTALS)., temperature 277K
Resolution 2.10 Å R-free 0.296
1T6B Crystal structure of B. anthracis Protective Antigen complexed with human Anthrax toxin receptor Deposited 2004-05-05 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain X 30–764（735 aa）
Not recorded CA CALCIUM ION × 2 NA SODIUM ION × 2 PG4 TETRAETHYLENE GLYCOL × 1 MN MANGANESE (II) ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 9；300 K；CHES buffer, PEG400, pH 9.0, VAPOR DIFFUSION, SITTING DROP, temperature 300K
Resolution 2.50 Å R-free 0.266
1TZN Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore bound to the VWA domain of CMG2, an anthrax toxin receptor Deposited 2004-07-10 Assembly 1 Protein heterocomplex Heteromer；Protein × 14 PDB declaration: tetradecameric（14） Consistent with protein count
Chain A 203–764（562 aa） Fragment：63-kDa domain
Chain B 203–764（562 aa） Fragment：63-kDa domain
Chain C 203–764（562 aa） Fragment：63-kDa domain
Chain D 203–764（562 aa） Fragment：63-kDa domain
Chain E 203–764（562 aa） Fragment：63-kDa domain
Chain F 203–764（562 aa） Fragment：63-kDa domain
Chain O 203–764（562 aa） Fragment：63-kDa domain
Not recorded CA CALCIUM ION × 14 MG MAGNESIUM ION × 7 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277 K；PEG 8000, sodium chloride, Tris, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 4.30 Å R-free 0.330
1TZN Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore bound to the VWA domain of CMG2, an anthrax toxin receptor Deposited 2004-07-10 Assembly 2 Protein heterocomplex Heteromer；Protein × 14 PDB declaration: tetradecameric（14） Consistent with protein count
Chain G 203–764（562 aa） Fragment：63-kDa domain
Chain H 203–764（562 aa） Fragment：63-kDa domain
Chain I 203–764（562 aa） Fragment：63-kDa domain
Chain J 203–764（562 aa） Fragment：63-kDa domain
Chain K 203–764（562 aa） Fragment：63-kDa domain
Chain L 203–764（562 aa） Fragment：63-kDa domain
Chain M 203–764（562 aa） Fragment：63-kDa domain
Not recorded CA CALCIUM ION × 14 MG MAGNESIUM ION × 7 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277 K；PEG 8000, sodium chloride, Tris, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 4.30 Å R-free 0.330
1TZN Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore bound to the VWA domain of CMG2, an anthrax toxin receptor Deposited 2004-07-10 Assembly 3 Protein heterocomplex Heteromer；Protein × 28 PDB declaration: 28-meric（28） Consistent with protein count
Chain A 203–764（562 aa） Fragment：63-kDa domain
Chain B 203–764（562 aa） Fragment：63-kDa domain
Chain C 203–764（562 aa） Fragment：63-kDa domain
Chain D 203–764（562 aa） Fragment：63-kDa domain
Chain E 203–764（562 aa） Fragment：63-kDa domain
Chain F 203–764（562 aa） Fragment：63-kDa domain
Chain G 203–764（562 aa） Fragment：63-kDa domain
Chain H 203–764（562 aa） Fragment：63-kDa domain
Chain I 203–764（562 aa） Fragment：63-kDa domain
Chain J 203–764（562 aa） Fragment：63-kDa domain
Chain K 203–764（562 aa） Fragment：63-kDa domain
Chain L 203–764（562 aa） Fragment：63-kDa domain
Chain M 203–764（562 aa） Fragment：63-kDa domain
Chain O 203–764（562 aa） Fragment：63-kDa domain
Not recorded CA CALCIUM ION × 28 MG MAGNESIUM ION × 14 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277 K；PEG 8000, sodium chloride, Tris, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 4.30 Å R-free 0.330
1TZN Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore bound to the VWA domain of CMG2, an anthrax toxin receptor Deposited 2004-07-10 Assembly 4 Protein heterocomplex Heteromer；Protein × 28 PDB declaration: 28-meric（28） Consistent with protein count
Chain A 203–764（562 aa） Fragment：63-kDa domain
Chain B 203–764（562 aa） Fragment：63-kDa domain
Chain C 203–764（562 aa） Fragment：63-kDa domain
Chain D 203–764（562 aa） Fragment：63-kDa domain
Chain E 203–764（562 aa） Fragment：63-kDa domain
Chain F 203–764（562 aa） Fragment：63-kDa domain
Chain G 203–764（562 aa） Fragment：63-kDa domain
Chain H 203–764（562 aa） Fragment：63-kDa domain
Chain I 203–764（562 aa） Fragment：63-kDa domain
Chain J 203–764（562 aa） Fragment：63-kDa domain
Chain K 203–764（562 aa） Fragment：63-kDa domain
Chain L 203–764（562 aa） Fragment：63-kDa domain
Chain M 203–764（562 aa） Fragment：63-kDa domain
Chain O 203–764（562 aa） Fragment：63-kDa domain
Not recorded CA CALCIUM ION × 28 MG MAGNESIUM ION × 14 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277 K；PEG 8000, sodium chloride, Tris, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 4.30 Å R-free 0.330
1TZN Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore bound to the VWA domain of CMG2, an anthrax toxin receptor Deposited 2004-07-10 Assembly 5 Protein heterocomplex Heteromer；Protein × 28 PDB declaration: 28-meric（28） Consistent with protein count
Chain A 203–764（562 aa） Fragment：63-kDa domain
Chain B 203–764（562 aa） Fragment：63-kDa domain
Chain C 203–764（562 aa） Fragment：63-kDa domain
Chain D 203–764（562 aa） Fragment：63-kDa domain
Chain E 203–764（562 aa） Fragment：63-kDa domain
Chain F 203–764（562 aa） Fragment：63-kDa domain
Chain G 203–764（562 aa） Fragment：63-kDa domain
Chain H 203–764（562 aa） Fragment：63-kDa domain
Chain I 203–764（562 aa） Fragment：63-kDa domain
Chain J 203–764（562 aa） Fragment：63-kDa domain
Chain K 203–764（562 aa） Fragment：63-kDa domain
Chain L 203–764（562 aa） Fragment：63-kDa domain
Chain M 203–764（562 aa） Fragment：63-kDa domain
Chain O 203–764（562 aa） Fragment：63-kDa domain
Not recorded CA CALCIUM ION × 28 MG MAGNESIUM ION × 14 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277 K；PEG 8000, sodium chloride, Tris, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 4.30 Å R-free 0.330
1TZO Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore Deposited 2004-07-10 Assembly 1 Protein homooligomer Homooligomer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count
Chain A 203–764（562 aa） Fragment：63-kDa domain
Chain B 203–764（562 aa） Fragment：63-kDa domain
Chain C 203–764（562 aa） Fragment：63-kDa domain
Chain D 203–764（562 aa） Fragment：63-kDa domain
Chain E 203–764（562 aa） Fragment：63-kDa domain
Chain F 203–764（562 aa） Fragment：63-kDa domain
Chain O 203–764（562 aa） Fragment：63-kDa domain
Not recorded CA CALCIUM ION × 14 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.25；298 K；HEPES, sodium chloride, b-octylglucoside, spermine, pH 8.25, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 3.60 Å R-free 0.317
1TZO Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore Deposited 2004-07-10 Assembly 2 Protein homooligomer Homooligomer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count
Chain G 203–764（562 aa） Fragment：63-kDa domain
Chain H 203–764（562 aa） Fragment：63-kDa domain
Chain I 203–764（562 aa） Fragment：63-kDa domain
Chain J 203–764（562 aa） Fragment：63-kDa domain
Chain K 203–764（562 aa） Fragment：63-kDa domain
Chain L 203–764（562 aa） Fragment：63-kDa domain
Chain M 203–764（562 aa） Fragment：63-kDa domain
Not recorded CA CALCIUM ION × 14 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.25；298 K；HEPES, sodium chloride, b-octylglucoside, spermine, pH 8.25, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 3.60 Å R-free 0.317
25PV Structure of the anthrax protective antigen in complex with a potent neutralizing antibody Deposited 2026-04-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 200–626（427 aa）
Mutation：F231S No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.03 Å
3ETB Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4 Deposited 2008-10-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain J 621–764（144 aa） Fragment：Domain 4 of protective antigen PA-63: UNP residues 621-764
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；10% PEG 20000, 0.05 M Tris-HCl, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 3.80 Å R-free 0.276
3ETB Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4 Deposited 2008-10-07 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain K 621–764（144 aa） Fragment：Domain 4 of protective antigen PA-63: UNP residues 621-764
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；10% PEG 20000, 0.05 M Tris-HCl, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 3.80 Å R-free 0.276
3ETB Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4 Deposited 2008-10-07 Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain L 621–764（144 aa） Fragment：Domain 4 of protective antigen PA-63: UNP residues 621-764
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；10% PEG 20000, 0.05 M Tris-HCl, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 3.80 Å R-free 0.276
3ETB Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4 Deposited 2008-10-07 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain M 621–764（144 aa） Fragment：Domain 4 of protective antigen PA-63: UNP residues 621-764
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；277 K；10% PEG 20000, 0.05 M Tris-HCl, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K
Resolution 3.80 Å R-free 0.276
3INO 1.95A Resolution Structure of Protective Antigen Domain 4 Deposited 2009-08-12 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 624–764（141 aa） Fragment：Domain 4
Chain B 624–764（141 aa） Fragment：Domain 4
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 6.5；277 K；20% PEG 8000, 100mM imidazole, 3% MPD, pH 6.5, vapor diffusion, temperature 277K
Resolution 1.95 Å R-free 0.258
3INO 1.95A Resolution Structure of Protective Antigen Domain 4 Deposited 2009-08-12 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 624–764（141 aa） Fragment：Domain 4
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 6.5；277 K；20% PEG 8000, 100mM imidazole, 3% MPD, pH 6.5, vapor diffusion, temperature 277K
Resolution 1.95 Å R-free 0.258
3INO 1.95A Resolution Structure of Protective Antigen Domain 4 Deposited 2009-08-12 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 624–764（141 aa） Fragment：Domain 4
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 6.5；277 K；20% PEG 8000, 100mM imidazole, 3% MPD, pH 6.5, vapor diffusion, temperature 277K
Resolution 1.95 Å R-free 0.258
3J9C CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution Deposited 2014-12-25 Assembly 1 Protein homooligomer Homooligomer；Protein × 7 PDB declaration: 7-MERIC（7） Consistent with protein count
Chain A 203–764（562 aa） Fragment：C-terminal 63-kDa fragment (UNP residues 203-764)
Not recorded CA CALCIUM ION × 14 ELECTRON MICROSCOPY
cryo-EM buffer 50 mM NaOAc, pH 5.0, 0.05% Igepal CA-630；pH 5；50 mM NaOAc, pH 5.0, 0.05% Igepal CA-630
cryo-EM vitrification conditions Cryogen ETHANE；Plunged into liguid nitrogen (FEI VITROBOT MARK IV).
Resolution 2.90 Å
3J9C CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution Deposited 2014-12-25 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 203–764（562 aa） Fragment：C-terminal 63-kDa fragment (UNP residues 203-764)
Not recorded CA CALCIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer 50 mM NaOAc, pH 5.0, 0.05% Igepal CA-630；pH 5；50 mM NaOAc, pH 5.0, 0.05% Igepal CA-630
cryo-EM vitrification conditions Cryogen ETHANE；Plunged into liguid nitrogen (FEI VITROBOT MARK IV).
Resolution 2.90 Å
3J9C CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution Deposited 2014-12-25 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 203–764（562 aa） Fragment：C-terminal 63-kDa fragment (UNP residues 203-764)
Not recorded CA CALCIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer 50 mM NaOAc, pH 5.0, 0.05% Igepal CA-630；pH 5；50 mM NaOAc, pH 5.0, 0.05% Igepal CA-630
cryo-EM vitrification conditions Cryogen ETHANE；Plunged into liguid nitrogen (FEI VITROBOT MARK IV).
Resolution 2.90 Å
3KWV Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers Deposited 2009-12-01 Assembly 1 Protein heterocomplex Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain A 197–764（568 aa） Fragment：UNP residues 197-764
Chain B 197–764（568 aa） Fragment：UNP residues 197-764
Mutation：V303P, H304G Mutation：V303P, H304G CA CALCIUM ION × 16 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.2；291 K；16% PEG 3000, 0.1M cacodylic acid, 0.2M magnesium chloride, 10 mM Tris-Cl, 75 mM sodium chloride, 10 mM adenosine-5'-triphosphate, pH 7.2, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.10 Å R-free 0.281
3KWV Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers Deposited 2009-12-01 Assembly 2 Protein heterocomplex Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain D 197–764（568 aa） Fragment：UNP residues 197-764
Chain E 197–764（568 aa） Fragment：UNP residues 197-764
Mutation：V303P, H304G Mutation：V303P, H304G CA CALCIUM ION × 16 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.2；291 K；16% PEG 3000, 0.1M cacodylic acid, 0.2M magnesium chloride, 10 mM Tris-Cl, 75 mM sodium chloride, 10 mM adenosine-5'-triphosphate, pH 7.2, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 3.10 Å R-free 0.281
3MHZ 1.7A structure of 2-fluorohistidine labeled Protective Antigen Deposited 2010-04-09 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) CA CALCIUM ION × 2 PG4 TETRAETHYLENE GLYCOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.2；293 K；30% PEG 400, 0.1M Tris, pH 8.2, vapor diffusion, temperature 293K
Resolution 1.70 Å R-free 0.222
3Q8A Crystal structure of WT Protective Antigen (pH 5.5) Deposited 2011-01-06 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa）
Not recorded CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 5.5；293 K；25 %(w/v) PEG 1500, 100 mM SPG Buffer, pH 5.5, vapor diffusion, temperature 293K
Resolution 3.13 Å R-free 0.279
3Q8B Crystal structure of WT Protective Antigen (pH 9.0) Deposited 2011-01-06 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa）
Not recorded CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 9；293 K；25 %(w/v) PEG 1500, 100 mM MMT Buffer, pH 9.0, vapor diffusion, temperature 293K
Resolution 2.00 Å R-free 0.258
3Q8C Crystal structure of Protective Antigen W346F (pH 5.5) Deposited 2011-01-06 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa）
Mutation：W346F CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 5.5；293 K；25%(w/v) PEG 1500, 100mM SPG Buffer, pH 5.5, vapor diffusion, temperature 293K
Resolution 2.85 Å R-free 0.271
3Q8E Crystal structure of Protective Antigen W346F (pH 8.5) Deposited 2011-01-06 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa）
Mutation：W346F CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8.5；293 K；25%(w/v) PEG 1500, 100mM SPG Buffer, pH 8.5, vapor diffusion, temperature 293K
Resolution 2.10 Å R-free 0.248
3Q8F Crystal structure of 2-Fluorohistine labeled Protective Antigen (pH 5.8) Deposited 2011-01-06 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) CA CALCIUM ION × 2 PG4 TETRAETHYLENE GLYCOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；293 K；30% PEG 400, 100mM MES, pH 7.0, vapor diffusion, temperature 293K
Resolution 2.10 Å R-free 0.267
3TEZ Crystal Structure of Anthrax Protective Antigen Mutant S337C N664C and dithiolacetone modified to 1.8-A resolution Deposited 2011-08-15 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa）
Mutation：S337C,N664C CA CALCIUM ION × 2 MXE 2-METHOXYETHANOL × 2 ACN ACETONE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；292 K；20% PEG-ME 2000, 0.1M Tris-Cl, 0.2M Trimethylamine-N-oxide, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 292K
Resolution 1.83 Å R-free 0.226
4EE2 Crystal Structure of Anthrax Protective Antigen K446M Mutant to 1.91-A Resolution Deposited 2012-03-28 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa） Fragment：Protective antigen
Mutation：K446M CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；292 K；0.1M tris, 20% peg2k-MME, 0.2M TMAO, pH 8, VAPOR DIFFUSION, HANGING DROP, temperature 292K
Resolution 1.91 Å R-free 0.265
4H2A Crystal structure of wild type protective antigen to 1.62 A (pH 7.5) Deposited 2012-09-12 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa）
Not recorded EDO 1,2-ETHANEDIOL × 4 CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；280 K；protein crystallised from 0.1 M HEPES pH 7.5, 10 % PEG 8000, 8 % ethylene glycol by sitting drop vapour diffusion at temperature 280 K., VAPOR DIFFUSION, SITTING DROP
Resolution 1.62 Å R-free 0.219
4NAM 1.7A structure of 5-Fluoro Tryptophan Labeled Protective Antigen (W206Y) Deposited 2013-10-22 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 30–764（735 aa）
Mutation：W206Y Non-standard monomer：Yes (specific site not provided by mmCIF) CA CALCIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7.5；293 K；35% (v/v) Pentaerythritol propoxylate (5/4 PO/OH), 0.05 M HEPES, 0.2 M Potassium chloride, pH 7.5, vapor diffusion, temperature 293K
Resolution 1.70 Å R-free 0.208
5FR3 X-ray crystal structure of aggregation-resistant protective antigen of Bacillus anthracis (mutant S559L T576E) Deposited 2015-12-15 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 43–764（722 aa）
Mutation：YES CA CALCIUM ION × 2 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions 20 MM MGCL2, 100 MM HEPES PH 7.5, 22% POLY(ACRYLIC ACID SODIUM SALT) 5100
Resolution 1.94 Å R-free 0.227
6PSN Anthrax toxin protective antigen channels bound to lethal factor Deposited 2019-07-12 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain A 197–764（568 aa）
Chain B 197–764（568 aa）
Chain C 197–764（568 aa）
Chain D 197–764（568 aa）
Chain E 197–764（568 aa）
Chain F 197–764（568 aa）
Chain G 197–764（568 aa）
Not recorded CA CALCIUM ION × 14 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.60 Å
6UJI Low resolution crystal structure (5.5 A) of the anthrax toxin protective antigen heptamer prepore D425A mutant Deposited 2019-10-03 Assembly 1 Protein homooligomer Homooligomer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count
Chain A 197–764（568 aa）
Chain B 197–764（568 aa）
Chain C 197–764（568 aa）
Chain D 197–764（568 aa）
Chain E 197–764（568 aa）
Chain F 197–764（568 aa）
Chain G 197–764（568 aa）
Mutation：D425A Mutation：D425A Mutation：D425A Mutation：D425A Mutation：D425A Mutation：D425A Mutation：D425A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；291 K；10% (v/v) ethanol, 0.1 M Tris
Resolution 5.50 Å R-free 0.278
6UJI Low resolution crystal structure (5.5 A) of the anthrax toxin protective antigen heptamer prepore D425A mutant Deposited 2019-10-03 Assembly 2 Protein homooligomer Homooligomer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count
Chain H 197–764（568 aa）
Chain I 197–764（568 aa）
Chain J 197–764（568 aa）
Chain K 197–764（568 aa）
Chain L 197–764（568 aa）
Chain M 197–764（568 aa）
Chain N 197–764（568 aa）
Mutation：D425A Mutation：D425A Mutation：D425A Mutation：D425A Mutation：D425A Mutation：D425A Mutation：D425A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；291 K；10% (v/v) ethanol, 0.1 M Tris
Resolution 5.50 Å R-free 0.278
6UZB Anthrax toxin protective antigen channels bound to edema factor Deposited 2019-11-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain A 30–764（735 aa）
Chain B 30–764（735 aa）
Chain C 30–764（735 aa）
Chain D 30–764（735 aa）
Chain E 30–764（735 aa）
Chain F 30–764（735 aa）
Chain G 30–764（735 aa）
Not recorded CA CALCIUM ION × 14 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å
6UZD Anthrax toxin protective antigen channels bound to edema factor Deposited 2019-11-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count
Chain A 30–764（735 aa）
Chain B 30–764（735 aa）
Chain C 30–764（735 aa）
Chain D 30–764（735 aa）
Chain E 30–764（735 aa）
Chain F 30–764（735 aa）
Chain G 30–764（735 aa）
Not recorded CA CALCIUM ION × 14 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
6UZE Anthrax toxin protective antigen channels bound to edema factor Deposited 2019-11-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count
Chain A 30–764（735 aa）
Chain B 30–764（735 aa）
Chain C 30–764（735 aa）
Chain D 30–764（735 aa）
Chain E 30–764（735 aa）
Chain F 30–764（735 aa）
Chain G 30–764（735 aa）
Not recorded CA CALCIUM ION × 14 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
6VRA Anthrax octamer prechannel bound to full-length edema factor Deposited 2020-02-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain A 33–764（732 aa）
Chain B 33–764（732 aa）
Chain C 33–764（732 aa）
Chain D 33–764（732 aa）
Chain E 33–764（732 aa）
Chain F 33–764（732 aa）
Chain G 33–764（732 aa）
Chain H 33–764（732 aa）
Mutation：K245G, R252N Mutation：D512K Mutation：K245G, R252N Mutation：D512K Mutation：K245G, R252N Mutation：D512K Mutation：K245G, R252N Mutation：D512K CA CALCIUM ION × 16 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.30 Å
6WJJ Anthrax octamer prechannel bound to full-length lethal factor Deposited 2020-04-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain A 33–764（732 aa）
Chain B 33–764（732 aa）
Chain C 33–764（732 aa）
Chain D 33–764（732 aa）
Chain E 33–764（732 aa）
Chain F 33–764（732 aa）
Chain G 33–764（732 aa）
Chain H 33–764（732 aa）
Not recorded CA CALCIUM ION × 16 SO4 SULFATE ION × 4 ZN ZINC ION × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.80 Å
7KXR Protective antigen pore translocating lethal factor N-terminal domain Deposited 2020-12-04 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain A 203–764（562 aa） Fragment：UNP Residues 203-764
Chain B 203–764（562 aa） Fragment：UNP Residues 203-764
Chain C 203–764（562 aa） Fragment：UNP Residues 203-764
Chain D 203–764（562 aa） Fragment：UNP Residues 203-764
Chain E 203–764（562 aa） Fragment：UNP Residues 203-764
Chain F 203–764（562 aa） Fragment：UNP Residues 203-764
Chain G 203–764（562 aa） Fragment：UNP Residues 203-764
Not recorded CA CALCIUM ION × 14 ELECTRON MICROSCOPY
cryo-EM buffer pH 5.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.30 Å
7O85 Anthrax toxin prepore in complex with the neutralizing Fab cAb29 Deposited 2021-04-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 21 PDB declaration: 21-meric（21） Consistent with protein count
Chain A 203–643（441 aa）
Chain D 203–643（441 aa）
Chain G 203–643（441 aa）
Chain J 203–643（441 aa）
Chain M 203–643（441 aa）
Chain P 203–643（441 aa）
Chain S 203–643（441 aa）
Not recorded CA CALCIUM ION × 14 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.30 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.