Current Protein Identity：P25054
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1DEB CRYSTAL STRUCTURE OF THE N-TERMINAL COILED COIL DOMAIN FROM APC Deposited 1999-11-14 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–55（54 aa）
Fragment：N-TERMINAL COILED COIL DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.8；277 K；15% PEG 4000, 0.1M AMMONIUM ACETATE, 0.1M NA ACETATE, pH 4.8, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.40 Å R-free 0.277 |
| 1DEB CRYSTAL STRUCTURE OF THE N-TERMINAL COILED COIL DOMAIN FROM APC Deposited 1999-11-14 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
2–55（54 aa）
Fragment：N-TERMINAL COILED COIL DOMAIN
|
Not recorded | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.8；277 K；15% PEG 4000, 0.1M AMMONIUM ACETATE, 0.1M NA ACETATE, pH 4.8, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.40 Å R-free 0.277 |
| 1DEB CRYSTAL STRUCTURE OF THE N-TERMINAL COILED COIL DOMAIN FROM APC Deposited 1999-11-14 | Assembly 3 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
2–55（54 aa）
Fragment：N-TERMINAL COILED COIL DOMAIN
Chain B
2–55（54 aa）
Fragment：N-TERMINAL COILED COIL DOMAIN
|
Not recorded | SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.8；277 K；15% PEG 4000, 0.1M AMMONIUM ACETATE, 0.1M NA ACETATE, pH 4.8, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.40 Å R-free 0.277 |
| 1DEB CRYSTAL STRUCTURE OF THE N-TERMINAL COILED COIL DOMAIN FROM APC Deposited 1999-11-14 | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–55（54 aa）
Fragment：N-TERMINAL COILED COIL DOMAIN
Chain B
2–55（54 aa）
Fragment：N-TERMINAL COILED COIL DOMAIN
|
Not recorded | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.8；277 K；15% PEG 4000, 0.1M AMMONIUM ACETATE, 0.1M NA ACETATE, pH 4.8, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.40 Å R-free 0.277 |
| 1DEB CRYSTAL STRUCTURE OF THE N-TERMINAL COILED COIL DOMAIN FROM APC Deposited 1999-11-14 | Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–55（54 aa）
Fragment：N-TERMINAL COILED COIL DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.8；277 K；15% PEG 4000, 0.1M AMMONIUM ACETATE, 0.1M NA ACETATE, pH 4.8, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.40 Å R-free 0.277 |
| 1EMU STRUCTURE OF THE AXIN RGS-HOMOLOGOUS DOMAIN IN COMPLEX WITH A SAMP REPEAT FROM APC Deposited 2000-03-17 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
2034–2049（16 aa）
Fragment：THIRD SAMP REPEAT
|
Not recorded | GOL GLYCEROL × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；MES, PEG 400, glycerol, DTT, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.90 Å R-free 0.221 |
| 1JPP The Structure of a beta-Catenin Binding Repeat from Adenomatous Polyposis Coli (APC) in Complex with beta-Catenin Deposited 2001-08-02 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
1021–1035（15 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.2；293 K；PEG 8000, sodium potassium phosphate, sodium chloride, DTT, pH 6.2, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.10 Å R-free 0.274 |
| 1JPP The Structure of a beta-Catenin Binding Repeat from Adenomatous Polyposis Coli (APC) in Complex with beta-Catenin Deposited 2001-08-02 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
1021–1035（15 aa）
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.2；293 K；PEG 8000, sodium potassium phosphate, sodium chloride, DTT, pH 6.2, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.10 Å R-free 0.274 |
| 1M5I Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC Deposited 2002-07-09 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
126–250（125 aa）
Fragment：coiled-coil region
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；277 K；16% PEG 3350, 100mM potassium iodide, 10mM strontium chloride, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.00 Å R-free 0.309 |
| 1T08 Crystal structure of beta-catenin/ICAT helical domain/unphosphorylated APC R3 Deposited 2004-04-07 | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain C
1484–1498（15 aa）
Fragment：repeat 3 (RESIDUES 1484-1498)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6.5；297 K；PEG3400, Potassium phosphate, pH 6.5, EVAPORATION, temperature 297K
|
Resolution 2.10 Å R-free 0.241 |
| 1TH1 Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment Deposited 2004-05-31 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
1362–1540（179 aa）
Fragment：phosphorylated 20 amino acid repeat
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；Tris, sidium chloride, PEG2000MME, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.50 Å R-free 0.257 |
| 1TH1 Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment Deposited 2004-05-31 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
1362–1540（179 aa）
Fragment：phosphorylated 20 amino acid repeat
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；Tris, sidium chloride, PEG2000MME, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.50 Å R-free 0.257 |
| 1V18 The crystal structure of beta-catenin armadillo repeat complexed with a phosphorylated APC 20mer repeat. Deposited 2004-04-09 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1482–1528（47 aa）
Fragment：RESIDUES 1482-1528
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5；pH 6.50
|
Resolution 2.10 Å R-free 0.253 |
| 2RQU Solution structure of the complex between the DDEF1 SH3 domain and the APC SAMP1 motif Deposited 2009-12-14 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1578–1596（19 aa）
Fragment：UNP residues 1578-1596
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7.2；278 K；Pressure ambient
NMR sample composition
0.5 mM [U-15N] DDEF1 SH3-1, 0.5 mM [U-15N] APC SAMP1-2, 5 mM sodium phosphate-3, 5 mM [U-2H] DTT-4, 0.02 % sodium azide-5, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.5 mM [U-13C; U-15N] DDEF1 SH3-6, 0.5 mM [U-13C; U-15N] APC SAMP1-7, 5 mM sodium phosphate-8, 5 mM [U-2H] DTT-9, 0.02 % sodium azide-10, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.5 mM [U-13C; U-15N] DDEF1 SH3-11, 0.5 mM [U-13C; U-15N] APC SAMP1-12, 5 mM sodium phosphate-13, 5 mM [U-2H] DTT-14, 0.02 % sodium phosphate-15, 100% D2O | 100% D2O
NMR sample composition
0.5 mM [U-15% 13C; U-15N] DDEF1 SH3-16, 0.5 mM [U-15% 13C; U-15N] APC SAMP1-17, 5 mM sodium phosphate-18, 5 mM [U-2H] DTT-19, 0.02 % sodium azide-20, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 3AU3 Crystal structure of armadillo repeat domain of APC Deposited 2011-01-28 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
396–732（337 aa）
Fragment：Armadillo repeat, UNP residues 396-732
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.6；293 K；100mM sodium acetate, 1.25M lithium citrate, pH 4.6, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.10 Å R-free 0.232 |
| 3QHE Crystal structure of the complex between the armadillo repeat domain of adenomatous polyposis coli and the tyrosine-rich domain of Sam68 Deposited 2011-01-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
396–732（337 aa）
Fragment：Armadillo repeat domain, residues 396-732
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；293 K；100mM BIS-TRIS (pH 5.5), 150mM NaCl, 20% PEG 3350, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.40 Å R-free 0.230 |
| 3QHE Crystal structure of the complex between the armadillo repeat domain of adenomatous polyposis coli and the tyrosine-rich domain of Sam68 Deposited 2011-01-25 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
396–732（337 aa）
Fragment：Armadillo repeat domain, residues 396-732
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；293 K；100mM BIS-TRIS (pH 5.5), 150mM NaCl, 20% PEG 3350, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.40 Å R-free 0.230 |
| 3RL7 Crystal structure of hDLG1-PDZ1 complexed with APC Deposited 2011-04-19 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain G
2833–2843（11 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；287 K；0.8M Na2HPO4, 0.9M KH2PO4, pH 7.5, vapor diffusion, hanging drop, temperature 287K
|
Resolution 2.30 Å R-free 0.231 |
| 3RL7 Crystal structure of hDLG1-PDZ1 complexed with APC Deposited 2011-04-19 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain H
2833–2843（11 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；287 K；0.8M Na2HPO4, 0.9M KH2PO4, pH 7.5, vapor diffusion, hanging drop, temperature 287K
|
Resolution 2.30 Å R-free 0.231 |
| 3RL7 Crystal structure of hDLG1-PDZ1 complexed with APC Deposited 2011-04-19 | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain J
2833–2843（11 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；287 K；0.8M Na2HPO4, 0.9M KH2PO4, pH 7.5, vapor diffusion, hanging drop, temperature 287K
|
Resolution 2.30 Å R-free 0.231 |
| 3RL7 Crystal structure of hDLG1-PDZ1 complexed with APC Deposited 2011-04-19 | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain I
2833–2843（11 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；287 K；0.8M Na2HPO4, 0.9M KH2PO4, pH 7.5, vapor diffusion, hanging drop, temperature 287K
|
Resolution 2.30 Å R-free 0.231 |
| 3RL7 Crystal structure of hDLG1-PDZ1 complexed with APC Deposited 2011-04-19 | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain K
2833–2843（11 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；287 K；0.8M Na2HPO4, 0.9M KH2PO4, pH 7.5, vapor diffusion, hanging drop, temperature 287K
|
Resolution 2.30 Å R-free 0.231 |
| 3RL7 Crystal structure of hDLG1-PDZ1 complexed with APC Deposited 2011-04-19 | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain L
2833–2843（11 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；287 K；0.8M Na2HPO4, 0.9M KH2PO4, pH 7.5, vapor diffusion, hanging drop, temperature 287K
|
Resolution 2.30 Å R-free 0.231 |
| 3RL8 Crystal structure of hDLG1-PDZ2 complexed with APC Deposited 2011-04-19 | Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count |
Chain F
2833–2843（11 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；287 K；0.8M Na2HPO4, 0.9M KH2PO4, pH 7.5, vapor diffusion, hanging drop, temperature 287K
|
Resolution 2.20 Å R-free 0.245 |
| 3T7U A NeW Crystal structure of APC-ARM Deposited 2011-07-31 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
407–775（369 aa）
Fragment：ARM 1-7 domain, UNP residues 407-775
|
Not recorded | PO4 PHOSPHATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；287 K；1.02M Sodium phosphate monobasic monohydrate, 0.18M Potassium phosphate dibasic, vapor diffusion, hanging drop, temperature 287K
|
Resolution 2.90 Å R-free 0.313 |
| 3T7U A NeW Crystal structure of APC-ARM Deposited 2011-07-31 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
407–775（369 aa）
Fragment：ARM 1-7 domain, UNP residues 407-775
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；287 K；1.02M Sodium phosphate monobasic monohydrate, 0.18M Potassium phosphate dibasic, vapor diffusion, hanging drop, temperature 287K
|
Resolution 2.90 Å R-free 0.313 |
| 4G69 Structure of the Human Discs Large 1 PDZ2 - Adenomatous Polyposis Coli Cytoskeletal Polarity Complex Deposited 2012-07-18 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
2833–2843（11 aa）
Fragment：APC C-terminal peptide, UNP residues 2833-2843
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.25；300 K；Protein solution: 1.4 mM Dlg1 PDZ2, 1.7 mM APC, 100 mM NaCl, 25 mM Tris pH 7.0, 0.1% B-ME
Well: 200 mM sodium acetate, 100 mM sodium cacodylate pH 6.25, 28% PEG 8000
Drop = 1:1 protein:well solution , VAPOR DIFFUSION, HANGING DROP, temperature 300K
|
Resolution 2.00 Å R-free 0.183 |
| 4YJE Crystal structure of APC-ARM in complexed with Amer1-A1 Deposited 2015-03-03 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–751（345 aa）
Fragment：ARM DOMAIN, UNP RESIDUES 407-751
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；287 K；12% PEG 20000
|
Resolution 1.90 Å R-free 0.221 |
| 4YJL Crystal structure of APC-ARM in complexed with Amer1-A2 Deposited 2015-03-03 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–751（345 aa）
Fragment：ARM DOMAIN, UNP RESIDUES 407-751
|
Not recorded | EDO 1,2-ETHANEDIOL × 9 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.2；287 K；0.2M NACL, 10% PEG 8000
|
Resolution 2.10 Å R-free 0.225 |
| 4YJL Crystal structure of APC-ARM in complexed with Amer1-A2 Deposited 2015-03-03 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
407–751（345 aa）
Fragment：ARM DOMAIN, UNP RESIDUES 407-751
|
Not recorded | EDO 1,2-ETHANEDIOL × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.2；287 K；0.2M NACL, 10% PEG 8000
|
Resolution 2.10 Å R-free 0.225 |
| 4YJL Crystal structure of APC-ARM in complexed with Amer1-A2 Deposited 2015-03-03 | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
407–751（345 aa）
Fragment：ARM DOMAIN, UNP RESIDUES 407-751
|
Not recorded | EDO 1,2-ETHANEDIOL × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.2；287 K；0.2M NACL, 10% PEG 8000
|
Resolution 2.10 Å R-free 0.225 |
| 4YJL Crystal structure of APC-ARM in complexed with Amer1-A2 Deposited 2015-03-03 | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
407–751（345 aa）
Fragment：ARM DOMAIN, UNP RESIDUES 407-751
|
Not recorded | EDO 1,2-ETHANEDIOL × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.2；287 K；0.2M NACL, 10% PEG 8000
|
Resolution 2.10 Å R-free 0.225 |
| 4YJL Crystal structure of APC-ARM in complexed with Amer1-A2 Deposited 2015-03-03 | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain E
407–751（345 aa）
Fragment：ARM DOMAIN, UNP RESIDUES 407-751
|
Not recorded | EDO 1,2-ETHANEDIOL × 7 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.2；287 K；0.2M NACL, 10% PEG 8000
|
Resolution 2.10 Å R-free 0.225 |
| 4YJL Crystal structure of APC-ARM in complexed with Amer1-A2 Deposited 2015-03-03 | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain F
407–751（345 aa）
Fragment：ARM DOMAIN, UNP RESIDUES 407-751
|
Not recorded | EDO 1,2-ETHANEDIOL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.2；287 K；0.2M NACL, 10% PEG 8000
|
Resolution 2.10 Å R-free 0.225 |
| 4YK6 Crystal structure of APC-ARM in complexed with Amer1-A4 Deposited 2015-03-04 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–751（345 aa）
Fragment：ARM DOMAIN, UNP RESIDUES 407-751
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.2；287 K；0.2M NACL, 10% PEG8000
|
Resolution 1.70 Å R-free 0.240 |
| 5B6G Protein-protein interaction Deposited 2016-05-27 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–751（345 aa）
Fragment：UNP RESIDUES 407-751
|
Not recorded | SO4 SULFATE ION × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；291 K；0.2 M Ammonium sulfate, 0.1 M Tris pH 8.0, 25 % w/v PEG 4000
|
Resolution 1.99 Å R-free 0.215 |
| 5IZ6 Protein-protein interaction Deposited 2016-03-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–751（345 aa）
Fragment：UNP RESIDUES 407-751
|
Not recorded | SO4 SULFATE ION × 1 PEG DI(HYDROXYETHYL)ETHER × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；291 K；0.2M Ammonium sulfate 0.1M Tris pH 8.0, 25% w/v PEG 3350
|
Resolution 2.15 Å R-free 0.206 |
| 5IZ8 Protein-protein interaction Deposited 2016-03-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–751（345 aa）
Fragment：UNP RESIDUES 407-751
|
Not recorded | PGE TRIETHYLENE GLYCOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；291 K；0.2M Ammonium sulfate, 0.1M Tris pH 8.0, 25% w/v PEG 4000
|
Resolution 3.06 Å R-free 0.253 |
| 5IZ8 Protein-protein interaction Deposited 2016-03-25 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
407–751（345 aa）
Fragment：UNP RESIDUES 407-751
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；291 K；0.2M Ammonium sulfate, 0.1M Tris pH 8.0, 25% w/v PEG 4000
|
Resolution 3.06 Å R-free 0.253 |
| 5IZ9 Protein-protein interaction Deposited 2016-03-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–751（345 aa）
Fragment：UNP RESIDUES 407-751
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；291 K；0.2M Ammonium sulfate, 0.1M Tris pH 8.0, 25 % w/v PEG 4000
|
Resolution 2.93 Å R-free 0.282 |
| 5IZA Protein-protein interaction Deposited 2016-03-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–751（345 aa）
Fragment：UNP RESIDUES 407-751
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；291 K；0.2M Ammonium sulfate, 0.1M Tris pH 8.0, 25% w/v PEG 4000
|
Resolution 1.50 Å R-free 0.159 |
| 5Z8H APC with an inhibitor Deposited 2018-01-31 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–741（335 aa）
|
Not recorded | GOL GLYCEROL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291 K；0.2M Ammonium sulfate 0.1M Tris pH 8.0, 25% w/v PEG 3350
|
Resolution 1.79 Å R-free 0.211 |
| 7F6M Crystal structure of APC complexed with a peptide inhibitor MAI-516 Deposited 2021-06-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–751（345 aa）
|
Not recorded | GOL GLYCEROL × 5 SO4 SULFATE ION × 2 PEG DI(HYDROXYETHYL)ETHER × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291 K；0.2M Ammonium sulfate 0.1M Tris pH 8.0, 25% w/v PEG 3350
|
Resolution 2.40 Å R-free 0.256 |
| 7F7O APC-Asef FP assay tracer Deposited 2021-06-30 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
407–738（332 aa）
|
Not recorded | 4CI N-[3',6'-bis(oxidanyl)-3-oxidanylidene-spiro[2-benzofuran-1,9'-xanthene]-5-yl]methanethioamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291 K；0.2M Ammonium sulfate, 0.1M Tris pH 8.0, 25% w/v PEG 3350
|
Resolution 2.80 Å R-free 0.328 |
| 7XTY Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide Deposited 2022-05-18 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
2833–2843（11 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 6.8；289 K；0.1M citric acid (pH 3.5), 3M NaCl
|
Resolution 2.10 Å R-free 0.240 |
| 7XTY Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide Deposited 2022-05-18 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
2833–2843（11 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 6.8；289 K；0.1M citric acid (pH 3.5), 3M NaCl
|
Resolution 2.10 Å R-free 0.240 |
| 8GSJ APC-Asef tripeptide inhibitor Deposited 2022-09-06 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
407–738（332 aa）
|
Not recorded | K8C 2-methylsulfanylpyrimidine-4-carbaldehyde × 1 GLU GLUTAMIC ACID × 1 NAL BETA-(2-NAPHTHYL)-ALANINE × 1 LEU LEUCINE × 1 GJZ (1R,2S)-2-phenylcyclopropanamine × 1 GOL GLYCEROL × 4 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291 K；0.2M Ammonium sulfate, 0.1M Tris pH 8.0, 25% w/v PEG 4000
|
Resolution 2.10 Å R-free 0.256 |
| 8X2Q The Crystal Structure of APC from Biortus. Deposited 2023-11-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
126–250（125 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；(PEG-G2) 0.2M NaAc pH 7.0, 20% PEG 3350
|
Resolution 2.00 Å R-free 0.263 |