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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P63142 New Search
17PDB entries
24Biological assembly
80chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1DSX KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT Deposited 2000-01-10 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 33–119（87 aa） Fragment：N-TERMINAL ASSEMBLY DOMAIN, RESIDUES 33-119
Chain B 33–119（87 aa） Fragment：N-TERMINAL ASSEMBLY DOMAIN, RESIDUES 33-119
Chain C 33–119（87 aa） Fragment：N-TERMINAL ASSEMBLY DOMAIN, RESIDUES 33-119
Chain D 33–119（87 aa） Fragment：N-TERMINAL ASSEMBLY DOMAIN, RESIDUES 33-119
Mutation：YES Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；22% PEG 1500, 5 % ISOPROPANOL, 200 MM NA ACETATE, 12 MM SRCL2, 50 MM TRIS, PH 8.5, pH 8.50
Resolution 1.60 Å R-free 0.279
1DSX KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT Deposited 2000-01-10 Assembly 2 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain E 33–119（87 aa） Fragment：N-TERMINAL ASSEMBLY DOMAIN, RESIDUES 33-119
Chain F 33–119（87 aa） Fragment：N-TERMINAL ASSEMBLY DOMAIN, RESIDUES 33-119
Chain G 33–119（87 aa） Fragment：N-TERMINAL ASSEMBLY DOMAIN, RESIDUES 33-119
Chain H 33–119（87 aa） Fragment：N-TERMINAL ASSEMBLY DOMAIN, RESIDUES 33-119
Mutation：YES Mutation：YES Mutation：YES Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；22% PEG 1500, 5 % ISOPROPANOL, 200 MM NA ACETATE, 12 MM SRCL2, 50 MM TRIS, PH 8.5, pH 8.50
Resolution 1.60 Å R-free 0.279
1QDV N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131 Deposited 1999-07-10 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 33–131（99 aa） Fragment：N-TERMINAL DOMAIN, RESIDUES 33-131
Chain B 33–131（99 aa） Fragment：N-TERMINAL DOMAIN, RESIDUES 33-131
Chain C 33–131（99 aa） Fragment：N-TERMINAL DOMAIN, RESIDUES 33-131
Chain D 33–131（99 aa） Fragment：N-TERMINAL DOMAIN, RESIDUES 33-131
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；291 K；19% PEG 4000, 100 MM NH4 ACETATE, 21% METHANOL, MES PH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 1.60 Å R-free 0.278
1QDW N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119 Deposited 1999-07-10 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 33–119（87 aa） Fragment：N-TERMINAL DOMAIN KV1.2, RESIDUES 33-119 (CORE)
Chain B 33–119（87 aa） Fragment：N-TERMINAL DOMAIN KV1.2, RESIDUES 33-119 (CORE)
Chain C 33–119（87 aa） Fragment：N-TERMINAL DOMAIN KV1.2, RESIDUES 33-119 (CORE)
Chain D 33–119（87 aa） Fragment：N-TERMINAL DOMAIN KV1.2, RESIDUES 33-119 (CORE)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；291 K；9% PEG 1500, 5% N-PROPANOL, 120 MM GDHCL 50 MM MES PH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.10 Å R-free 0.266
1QDW N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119 Deposited 1999-07-10 Assembly 2 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain E 33–119（87 aa） Fragment：N-TERMINAL DOMAIN KV1.2, RESIDUES 33-119 (CORE)
Chain F 33–119（87 aa） Fragment：N-TERMINAL DOMAIN KV1.2, RESIDUES 33-119 (CORE)
Chain G 33–119（87 aa） Fragment：N-TERMINAL DOMAIN KV1.2, RESIDUES 33-119 (CORE)
Chain H 33–119（87 aa） Fragment：N-TERMINAL DOMAIN KV1.2, RESIDUES 33-119 (CORE)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；291 K；9% PEG 1500, 5% N-PROPANOL, 120 MM GDHCL 50 MM MES PH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.10 Å R-free 0.266
2A79 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex Deposited 2005-07-05 Assembly 1 Protein heterocomplex Heteromer；Protein × 16 PDB declaration: hexadecameric（16） Consistent with protein count
Chain B 1–499（499 aa）
Not recorded NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 K POTASSIUM ION × 24 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；peg 400, potassium chloride, tris buffer, EDTA, DTT, TCEP, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.90 Å R-free 0.252
3LNM F233W mutant of the Kv2.1 paddle-Kv1.2 chimera channel Deposited 2010-02-02 Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain D 1–266（266 aa）
Chain D 303–499（197 aa）
Mutation：C31S, C32S, N207Q, F233W, C431S, C478S Mutation：C31S, C32S, N207Q, F233W, C431S, C478S NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 4 K POTASSIUM ION × 20 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；25-28% PEG 400, 50mM Tris-HCl, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.90 Å R-free 0.247
3LNM F233W mutant of the Kv2.1 paddle-Kv1.2 chimera channel Deposited 2010-02-02 Assembly 2 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 1–266（266 aa）
Chain B 303–499（197 aa）
Mutation：C31S, C32S, N207Q, F233W, C431S, C478S Mutation：C31S, C32S, N207Q, F233W, C431S, C478S NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 48 K POTASSIUM ION × 20 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；25-28% PEG 400, 50mM Tris-HCl, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.90 Å R-free 0.247
3LUT A Structural Model for the Full-length Shaker Potassium Channel Kv1.2 Deposited 2010-02-18 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 1–499（499 aa）
Mutation：N207Q NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 K POTASSIUM ION × 24 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.90 Å R-free 0.221
4JTA Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin Deposited 2013-03-23 Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 1–266（266 aa）
Chain B 304–499（196 aa）
Not recorded NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 K POTASSIUM ION × 12 PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 64 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.9；293 K；PEG 400, POTASSIUM CHLORIDE, TRIS , pH 8.9, vapor diffusion, hanging drop, temperature 293K
Resolution 2.50 Å R-free 0.236
4JTA Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin Deposited 2013-03-23 Assembly 2 Insufficient information Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count
Chain Q 1–266（266 aa）
Chain Q 304–499（196 aa）
Not recorded NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 K POTASSIUM ION × 12 PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.9；293 K；PEG 400, POTASSIUM CHLORIDE, TRIS , pH 8.9, vapor diffusion, hanging drop, temperature 293K
Resolution 2.50 Å R-free 0.236
4JTC Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+ Deposited 2013-03-23 Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 1–266（266 aa）
Chain B 304–499（196 aa）
Not recorded NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 CS CESIUM ION × 16 PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 64 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.9；293 K；PEG 400, Cesium CHLORIDE, TRIS BUFFER, pH 8.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.56 Å R-free 0.262
4JTC Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+ Deposited 2013-03-23 Assembly 2 Insufficient information Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count
Chain H 1–266（266 aa）
Chain H 304–499（196 aa）
Not recorded NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 CS CESIUM ION × 16 PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.9；293 K；PEG 400, Cesium CHLORIDE, TRIS BUFFER, pH 8.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.56 Å R-free 0.262
4JTD Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin Deposited 2013-03-23 Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 1–266（266 aa）
Chain B 304–499（196 aa）
Not recorded NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 K POTASSIUM ION × 16 PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 64 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.9；293 K；PEG 400, POTASSIUM CHLORIDE, TRIS , pH 8.9, vapor diffusion, hanging drop, temperature 293K
Resolution 2.54 Å R-free 0.235
4JTD Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin Deposited 2013-03-23 Assembly 2 Insufficient information Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count
Chain H 1–266（266 aa）
Chain H 304–499（196 aa）
Not recorded NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 K POTASSIUM ION × 16 PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.9；293 K；PEG 400, POTASSIUM CHLORIDE, TRIS , pH 8.9, vapor diffusion, hanging drop, temperature 293K
Resolution 2.54 Å R-free 0.235
5WIE Crystal structure of a Kv1.2-2.1 chimera K+ channel V406W mutant in an inactivated state Deposited 2017-07-19 Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 1–42（42 aa）
Mutation：V406W NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 20 K POTASSIUM ION × 16 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8；293 K；50 mM Tris-Cl pH 8.3, 29-31% PEG400
Resolution 3.30 Å R-free 0.243
5WIE Crystal structure of a Kv1.2-2.1 chimera K+ channel V406W mutant in an inactivated state Deposited 2017-07-19 Assembly 2 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain H 1–42（42 aa）
Mutation：V406W NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 PGW (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate × 4 K POTASSIUM ION × 16 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8；293 K；50 mM Tris-Cl pH 8.3, 29-31% PEG400
Resolution 3.30 Å R-free 0.243
6EBK The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs Deposited 2018-08-06 Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 1–266（266 aa）
Chain B 303–499（197 aa）
Chain D 1–266（266 aa）
Chain D 303–499（197 aa）
Chain F 1–266（266 aa）
Chain F 303–499（197 aa）
Chain H 1–266（266 aa）
Chain H 303–499（197 aa）
Not recorded NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；A 3 microliter sample was applied to a plasma-cleaned grid and blotted for 10 seconds.
Resolution 3.30 Å
6EBL The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, cytosolic domain Deposited 2018-08-06 Assembly 1 Insufficient information Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 1–266（266 aa）
Chain B 303–499（197 aa）
Chain D 1–266（266 aa）
Chain D 303–499（197 aa）
Chain F 1–266（266 aa）
Chain F 303–499（197 aa）
Chain H 1–266（266 aa）
Chain H 303–499（197 aa）
Not recorded NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；A 3 microliter sample was applied to a plasma-cleaned grid and blotted for 10 seconds.
Resolution 3.00 Å
6EBM The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, transmembrane domain of subunit alpha Deposited 2018-08-06 Assembly 1 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–266（266 aa）
Chain B 303–499（197 aa）
Chain D 1–266（266 aa）
Chain D 303–499（197 aa）
Chain F 1–266（266 aa）
Chain F 303–499（197 aa）
Chain H 1–266（266 aa）
Chain H 303–499（197 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE；A 3 microliter sample was applied to a plasma-cleaned grid and blotted for 10 seconds.
Resolution 4.00 Å
8VC3 Voltage gated potassium ion channel Kv1.2 in complex with DTx Deposited 2023-12-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain B 1–499（499 aa）
Chain C 1–499（499 aa）
Chain D 1–499（499 aa）
Chain E 1–499（499 aa）
Not recorded K POTASSIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å
8VC4 Voltage gated potassium ion channel Kv1.2 in Sodium Deposited 2023-12-13 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–499（499 aa）
Chain B 1–499（499 aa）
Chain C 1–499（499 aa）
Chain D 1–499（499 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.17 Å
8VC6 Voltage gated potassium ion channel Kv1.2 in Potassium Deposited 2023-12-13 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–499（499 aa）
Chain B 1–499（499 aa）
Chain C 1–499（499 aa）
Chain D 1–499（499 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.17 Å
8VCH Voltage gated potassium ion channel Kv1.2 W366F, C-type inactivated Deposited 2023-12-14 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 1–499（499 aa）
Chain B 1–499（499 aa）
Chain C 1–499（499 aa）
Chain D 1–499（499 aa）
Mutation：W366F Mutation：W366F Mutation：W366F Mutation：W366F K POTASSIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.55 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.