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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q00959 New Search
60PDB entries
62Biological assembly
113chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2A5S Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate Deposited 2005-06-30 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 401–539（139 aa） Fragment：S1S2 ligand-binding core
Not recorded GLU GLUTAMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7；277 K；PEG 8000, HEPES, calcium acetate, pH 7, EVAPORATION, temperature 277K
Resolution 1.70 Å R-free 0.223
2A5S Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate Deposited 2005-06-30 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 401–539（139 aa） Fragment：S1S2 ligand-binding core
Not recorded GLU GLUTAMIC ACID × 2 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7；277 K；PEG 8000, HEPES, calcium acetate, pH 7, EVAPORATION, temperature 277K
Resolution 1.70 Å R-free 0.223
2A5T Crystal Structure Of The NR1/NR2A ligand-binding cores complex Deposited 2005-06-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 401–539（139 aa） Fragment：S1S2 ligand-binding core
Not recorded GLY GLYCINE × 1 GLU GLUTAMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7；277 K；PEG 8000, HEPES, Calcium acetate, pH 7., EVAPORATION, temperature 277K
Resolution 2.00 Å R-free 0.253
4NF4 Crystal structure of GluN1/GluN2A ligand-binding domain in complex with DCKA and glutamate Deposited 2013-10-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：Ligand-binding domain; unp residues 402-539; unp residues 661-802
Chain B 661–802（142 aa） Fragment：Ligand-binding domain; unp residues 402-539; unp residues 661-802
Mutation：S758T Mutation：S758T 2JK 4-hydroxy-5,7-dimethylquinoline-2-carboxylic acid × 1 GLU GLUTAMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；300 K；PEG2000MME, HEPES, pH 7, VAPOR DIFFUSION, temperature 300K
Resolution 2.00 Å R-free 0.217
4NF5 Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and D-AP5 Deposited 2013-10-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：unp residues 402-539; unp residues 661-802
Chain B 661–802（142 aa） Fragment：unp residues 402-539; unp residues 661-802
Mutation：S758T Mutation：S758T GLY GLYCINE × 1 GOL GLYCEROL × 3 2JJ 5-phosphono-D-norvaline × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；300 K；PEG2000MME, HEPES, pH 7, VAPOR DIFFUSION, temperature 300K
Resolution 1.90 Å R-free 0.213
4NF6 Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and PPDA Deposited 2013-10-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：Ligand-binding domain; unp residues 402-539; unp residues 661-802
Chain B 661–802（142 aa） Fragment：Ligand-binding domain; unp residues 402-539; unp residues 661-802
Mutation：S758T Mutation：S758T GLY GLYCINE × 1 2JL (2S,3R)-1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；300 K；PEG2000MMG and HEPES, pH 7, VAPOR DIFFUSION, temperature 300K
Resolution 2.10 Å R-free 0.215
4NF8 Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and glutamate in PEG2000MME Deposited 2013-10-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：Ligand-binding domain; unp residues 402-539; unp residues 661-802
Chain B 661–802（142 aa） Fragment：Ligand-binding domain; unp residues 402-539; unp residues 661-802
Mutation：S758T Mutation：S758T GLY GLYCINE × 1 GLU GLUTAMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 7；300 K；PEG2000MME and HEPES, pH 7, VAPOR DIFFUSION, temperature 300K
Resolution 1.86 Å R-free 0.218
5DEX Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, phenyl-ACEPC Deposited 2015-08-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：UNP residues 402-539, 661-802
Chain B 661–802（142 aa） Fragment：UNP residues 402-539, 661-802
Not recorded GLY GLYCINE × 1 5E0 5-[(2R)-2-amino-2-carboxyethyl]-1-phenyl-1H-pyrazole-3-carboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；AMMONIUM ACETATE, PEG 4000
Resolution 2.40 Å R-free 0.285
5I56 Agonist-bound GluN1/GluN2A agonist binding domains with TCN201 Deposited 2016-02-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa）
Chain B 661–800（140 aa）
Not recorded GLY GLYCINE × 1 GLU GLUTAMIC ACID × 1 67P N-({4-[2-(benzenecarbonyl)hydrazinecarbonyl]phenyl}methyl)-3-chloro-4-fluorobenzene-1-sulfonamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.2 M ammonium sulfate and 16-22% PEG 4000
Resolution 2.28 Å R-free 0.239
5I57 Glutamate- and glycine-bound GluN1/GluN2A agonist binding domains Deposited 2016-02-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：unp residues 402-539; 661-800
Chain B 661–800（140 aa） Fragment：unp residues 402-539; 661-800
Not recorded GLY GLYCINE × 1 GLU GLUTAMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.2 M ammonium sulfate and 16-22% PEG 4000
Resolution 1.70 Å R-free 0.222
5I58 GLUTAMATE- AND GLYCINE-BOUND GLUN1/GLUN2A AGONIST BINDING DOMAINS WITH MPX-004 Deposited 2016-02-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa）
Chain B 661–800（140 aa）
Not recorded GLY GLYCINE × 1 GLU GLUTAMIC ACID × 1 67R 5-({[(3-chloro-4-fluorophenyl)sulfonyl]amino}methyl)-N-[(2-methyl-1,3-thiazol-5-yl)methyl]pyrazine-2-carboxamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；273 K；0.2 M ammonium sulfate and 16-22% PEG 4000
Resolution 2.52 Å R-free 0.292
5I59 Glutamate- and glycine-bound GluN1/GluN2A agonist binding domains with MPX 007 Deposited 2016-02-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa）
Chain B 661–800（140 aa）
Not recorded GLY GLYCINE × 1 GLU GLUTAMIC ACID × 1 67Q 5-({[(3,4-difluorophenyl)sulfonyl]amino}methyl)-6-methyl-N-[(2-methyl-4H-1lambda~4~,3-thiazol-5-yl)methyl]pyrazine-2-carboxamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.2 M ammonium sulfate and 16-22% PEG 4000
Resolution 2.25 Å R-free 0.264
5JTY Glutamate- and DCKA-bound GluN1/GluN2A agonist binding domains with MPX-007 Deposited 2016-05-10 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：unp residues 402-539; 661-800
Chain B 661–800（140 aa） Fragment：unp residues 402-539; 661-800
Not recorded 2JK 4-hydroxy-5,7-dimethylquinoline-2-carboxylic acid × 1 6ND 5-({[(3,4-difluorophenyl)sulfonyl]amino}methyl)-6-methyl-N-[(2-methyl-1,3-thiazol-5-yl)methyl]pyrazine-2-carboxamide × 1 GLU GLUTAMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；0.2 M AMMONIUM SULFATE AND 16-22% PEG 4000
Resolution 2.72 Å R-free 0.278
5TPW Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at the GluN2A Deposited 2016-10-21 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 34–393（360 aa） Fragment：residues 34-393
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 SO4 SULFATE ION × 6 GOL GLYCEROL × 2 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；1.8M Ammonium sulfate 2.5% Isopropanol
Resolution 2.91 Å R-free 0.245
5TQ0 Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in the presence of EDTA Deposited 2016-10-21 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 34–393（360 aa） Fragment：residues 34-393
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 GOL GLYCEROL × 2 SO4 SULFATE ION × 12 IPA ISOPROPYL ALCOHOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；1.8 M Ammonium sulfate, 2.5% Isopropanol
Resolution 2.70 Å R-free 0.246
5TQ2 Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at GluN1 and GluN2A Deposited 2016-10-21 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 34–393（360 aa） Fragment：residues 34-393
Not recorded ZN ZINC ION × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 SO4 SULFATE ION × 4 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；1.8M Ammonium sulfate, 2.5% Isopropanol
Resolution 3.29 Å R-free 0.261
5VIH Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-fluorophenyl-ACEPC Deposited 2017-04-16 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa）
Chain B 661–802（142 aa）
Not recorded GLY GLYCINE × 1 5DZ 5-[(2R)-2-amino-2-carboxyethyl]-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid × 1 PEG DI(HYDROXYETHYL)ETHER × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；Ammonia Acetate, PEG 4000
Resolution 2.40 Å R-free 0.272
5VII Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-(3-fluoropropyl)phenyl-ACEPC Deposited 2017-04-16 Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa）
Not recorded GLY GLYCINE × 1 5DY 5-[(2R)-2-amino-2-carboxyethyl]-1-[4-(3-fluoropropyl)phenyl]-1H-pyrazole-3-carboxylic acid × 1 PEG DI(HYDROXYETHYL)ETHER × 1 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；Ammonia Acetate, PEG 4000
Resolution 1.95 Å R-free 0.259
5VIJ Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-bromophenyl-ACEPC Deposited 2017-04-16 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa）
Chain B 661–802（142 aa）
Not recorded GLY GLYCINE × 1 5DX 5-[(2R)-2-amino-2-carboxyethyl]-1-(4-bromophenyl)-1H-pyrazole-3-carboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；Ammonia Acetate, PEG 4000
Resolution 2.10 Å R-free 0.255
6MM9 Diheteromeric NMDA receptor GluN1/GluN2A in the '1-Knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 6.1 Deposited 2018-09-29 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 34 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.1
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 5.97 Å
6MMA Diheteromeric NMDA receptor GluN1/GluN2A in the 'Extended' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 6.1 Deposited 2018-09-29 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 34 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.1
cryo-EM vitrification conditions Cryogen ETHANE；sample was blotted for 3 seconds at blot force 1.
Resolution 6.31 Å
6MMB Diheteromeric NMDA receptor GluN1/GluN2A in the 'Super-Splayed' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 6.1 Deposited 2018-09-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 34 ELECTRON MICROSCOPY
cryo-EM buffer pH 6.1
cryo-EM vitrification conditions Cryogen ETHANE；sample was blotted for 3 seconds at blot force 1.
Resolution 12.70 Å
6MMG Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar EDTA, and at pH 7.4 Deposited 2018-09-30 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 26 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；sample was blotted for 3 seconds at blot force 1.
Resolution 6.23 Å
6MMH Diheteromeric NMDA receptor GluN1/GluN2A in the 'Extended-2' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar zinc chloride, and at pH 7.4 Deposited 2018-09-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 34 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；sample was blotted for 3 seconds at blot force 1.
Resolution 8.21 Å
6MMI Diheteromeric NMDA receptor GluN1/GluN2A in the 'Splayed-Open' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar zinc chloride, and at pH 7.4 Deposited 2018-09-30 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 21 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；sample was blotted for 3 seconds at blot force 1.
Resolution 8.93 Å
6MMJ Diheteromeric NMDA receptor GluN1/GluN2A in the 'Super-Splayed' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar zinc chloride, and at pH 7.4 Deposited 2018-09-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 34 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；sample was blotted for 3 seconds at blot force 1.
Resolution 16.50 Å
6MMK Diheteromeric NMDA receptor GluN1/GluN2A in the '1-Knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 Deposited 2018-09-30 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 28 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 6.08 Å
6MML Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 Deposited 2018-09-30 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 30 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 7.14 Å
6MMM Diheteromeric NMDA receptor GluN1/GluN2A in the 'Extended-1' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 Deposited 2018-09-30 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 28 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 6.84 Å
6MMN Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 8.0 Deposited 2018-10-01 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 22 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；sample was blotted for 3 seconds at blot force 1.
Resolution 7.51 Å
6MMP Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 0.1 millimolar EDTA, and at pH 8.0 Deposited 2018-10-01 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 28 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；sample was blotted for 3 seconds at blot force 1.
Resolution 6.88 Å
6MMR Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar zinc chloride, 3 millimolar EDTA, and at pH 7.4 Deposited 2018-10-01 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 34 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 5.13 Å
6MMS Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar EDTA, and at pH 7.4 Deposited 2018-10-01 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Mutation：H128S, N687Q Mutation：H128S, N687Q NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 29 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 5.38 Å
6MMT Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '1-Knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 Deposited 2018-10-01 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Mutation：H128S, N687Q NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 29 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 7.46 Å
6MMU Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 Deposited 2018-10-01 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Mutation：H128S, N687Q NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 28 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 5.30 Å
6MMV Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* Extracellular Domain in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 Deposited 2018-10-01 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–800（800 aa） Fragment：UNP residues 1-800
Chain D 1–800（800 aa） Fragment：UNP residues 1-800
Mutation：H128S, N687Q NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 26 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 4.71 Å
6MMW Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 Deposited 2018-10-01 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Mutation：H128S, N687Q Mutation：H128S, N687Q NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 30 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 6.20 Å
6MMX Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the 'Extended' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 Deposited 2018-10-01 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–837（837 aa） Fragment：UNP residues 1-837
Chain D 1–837（837 aa） Fragment：UNP residues 1-837
Mutation：H128S, N687Q Mutation：H128S, N687Q NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 25 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted for 3 seconds at blot force 1.
Resolution 6.99 Å
6ODL Crystal structure of GluN2A agonist binding domain with 4-butyl-(S)-CCG-IV Deposited 2019-03-26 Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 404–539（136 aa）
Chain B 404–539（136 aa）
Not recorded M7V (1S,2R)-2-[(S)-amino(carboxy)methyl]-1-butylcyclopropane-1-carboxylic acid × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.2 M AMMONIUM SULFATE AND 16-22% PEG 4000
Resolution 2.30 Å R-free 0.283
6OVD Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 3-ethylphenyl-ACEPC Deposited 2019-05-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa）
Chain B 661–802（142 aa）
Not recorded GLY GLYCINE × 1 N9A (3S,5S)-5-[(2R)-2-amino-2-carboxyethyl]-1-(3-ethylphenyl)pyrazolidine-3-carboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.2 M AMMONIUM SULFATE AND 16-22% PEG 4000
Resolution 2.10 Å R-free 0.240
6OVE Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-propylphenyl-ACEPC Deposited 2019-05-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa）
Chain B 662–801（140 aa）
Not recorded GLY GLYCINE × 1 N9D (3R,5S)-5-[(2R)-2-amino-2-carboxyethyl]-1-(4-propylphenyl)pyrazolidine-3-carboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；0.2 M AMMONIUM SULFATE AND 16-22% PEG 4000
Resolution 2.00 Å R-free 0.216
6OVE Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-propylphenyl-ACEPC Deposited 2019-05-07 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 402–539（138 aa）
Chain B 662–801（140 aa）
Not recorded N9D (3R,5S)-5-[(2R)-2-amino-2-carboxyethyl]-1-(4-propylphenyl)pyrazolidine-3-carboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；0.2 M AMMONIUM SULFATE AND 16-22% PEG 4000
Resolution 2.00 Å R-free 0.216
6USU Crystal structure of GluN1/GluN2A ligand-binding domain in complex with L689,560 and glutamate Deposited 2019-10-28 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：UNP residues 402-539, 661-802
Chain B 661–802（142 aa） Fragment：UNP residues 402-539, 661-802
Not recorded QGM (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid × 1 GLU GLUTAMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7；291 K；0.2 M HEPES, pH 7.0, 60-90 mM sodium chloride, 15-20% PEG2000 MME
Resolution 2.09 Å R-free 0.222
6USV Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and SDZ 220-040 Deposited 2019-10-28 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：UNP residues 402-539, 661-802
Chain B 661–802（142 aa） Fragment：UNP residues 402-539, 661-802
Not recorded GLY GLYCINE × 1 QGP (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid × 1 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7；291 K；0.2 M HEPES, pH 7.0, 60-90 mM sodium chloride, 15-20% PEG2000 MME
Resolution 2.30 Å R-free 0.259
6UZ6 Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and glutamate Deposited 2019-11-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：ligand-binding domain (UNP residues 402-539,661-800)
Chain B 661–800（140 aa） Fragment：ligand-binding domain (UNP residues 402-539,661-800)
Mutation：A414R, K738M, G740R, R741K Mutation：A414R, K738M, G740R, R741K GLY GLYCINE × 1 GLU GLUTAMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；100 mM HEPES, pH 7.0, 75 mM sodium chloride, 18% PEG2000 MME
Resolution 1.66 Å R-free 0.212
6UZG Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and homoquinolinic acid Deposited 2019-11-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：ligand-binding domain (UNP residues 402-539,661-802)
Chain B 661–802（142 aa） Fragment：ligand-binding domain (UNP residues 402-539,661-802)
Mutation：A414R, K738M, G740R, R741K Mutation：A414R, K738M, G740R, R741K GLY GLYCINE × 1 QM1 3-(carboxymethyl)pyridine-2-carboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；100 mM HEPES, pH 7.0, 75 mM sodium chloride, 18% PEG2000 MME
Resolution 1.94 Å R-free 0.250
6UZR Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and homoquinolinic acid Deposited 2019-11-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：ligand-binding domain (UNP residues 402-539,661-802)
Chain B 661–802（142 aa） Fragment：ligand-binding domain (UNP residues 402-539,661-802)
Not recorded GLY GLYCINE × 1 GOL GLYCEROL × 3 QM1 3-(carboxymethyl)pyridine-2-carboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；100 mM HEPES, pH 7.0, 75 mM sodium chloride, 18% PEG2000 MME
Resolution 1.87 Å R-free 0.207
6UZW Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and UBP791 Deposited 2019-11-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：ligand-binding domain (UNP residues 402-539,661-802)
Chain B 661–802（142 aa） Fragment：ligand-binding domain (UNP residues 402-539,661-802)
Not recorded GLY GLYCINE × 1 QM4 (2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；100 mM HEPES, pH 7.0, 75 mM sodium chloride, 18% PEG2000 MME
Resolution 2.13 Å R-free 0.247
6UZX Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and UBP791 Deposited 2019-11-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa） Fragment：ligand-binding domain (UNP residues 402-539,661-802)
Chain B 661–802（142 aa） Fragment：ligand-binding domain (UNP residues 402-539,661-802)
Mutation：A414R, K738M, G740R, R741K Mutation：A414R, K738M, G740R, R741K GOL GLYCEROL × 2 GLY GLYCINE × 1 QM4 (2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；100 mM HEPES, pH 7.0, 75 mM sodium chloride, 18% PEG2000 MME
Resolution 2.41 Å R-free 0.245
8JF7 Triheteromeric NMDA receptor GluN1-GluN2A-GluN3A in complex with glycine, glutamate, a GluN1-specific Fab,and a GluN2A-specific Fab Deposited 2023-05-17 Assembly 1 Insufficient information Heteromer；Protein × 10 PDB declaration: decameric（10） Consistent with protein count
Chain B 1–842（842 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.73 Å
8XLK Structure of native tri-heteromeric GluN1-GluN2A-GluN2B NMDA receptor in rat cortex and hippocampus Deposited 2023-12-26 Assembly 1 Other combination Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain B 1–1464（1464 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 20 7RC (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.20 Å
9C7C Diheteromeric GluN1/GluN2A (delM653) in nanodisc complexed with glycine, glutamate, and GNE-4123, open conformation Deposited 2024-06-10 Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–865（865 aa）
Chain D 1–865（865 aa）
Not recorded A1AUV 4-cyclohexyl-N-[(8R)-2-cyclopropyl-7-hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]benzene-1-sulfonamide × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 24 HP6 HEPTANE × 1 Y01 CHOLESTEROL HEMISUCCINATE × 8 GLY GLYCINE × 2 D12 DODECANE × 2 GLU GLUTAMIC ACID × 2 D10 DECANE × 2 HEX HEXANE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
9C7E Diheteromeric GluN1/GluN2A (delM653) in nanodisc complex with glycine, glutamate, and GNE-4123, open conformation, C2 symmetry Deposited 2024-06-10 Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–866（866 aa）
Chain D 1–866（866 aa）
Not recorded A1AUV 4-cyclohexyl-N-[(8R)-2-cyclopropyl-7-hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]benzene-1-sulfonamide × 2 Y01 CHOLESTEROL HEMISUCCINATE × 6 D12 DODECANE × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.22 Å
9C7P Diheteromeric GluN1/GluN2A (delM653) in digitonin complexed with glycine, glutamate, and GNE-4123 Deposited 2024-06-10 Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–866（866 aa）
Chain D 1–866（866 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.61 Å
9C7Q Diheteromeric NMDA receptor GluN1/GluN2A, in complex with glycine and glutamate Deposited 2024-06-11 Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–866（866 aa）
Chain D 1–866（866 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.05 Å
9C7R Diheteromeric GluN1/GluN2A (M817V) in digitonin complexed with glycine, glutamate, and GNE-4123 Deposited 2024-06-11 Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–866（866 aa）
Chain D 1–866（866 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 15 ELECTRON MICROSCOPY
cryo-EM buffer pH 9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.99 Å
9DA9 Crystal structure of GluN1/GluN2A agonist-binding domains in complex with 7CKA and glutamate Deposited 2024-08-22 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–802（401 aa）
Not recorded CKA 7-Chlorokynurenic acid × 1 GLU GLUTAMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；0.2 M ammonium acetate and 14-18% PEG 4000
Resolution 2.05 Å R-free 0.228
9NYZ Crystal structure of DCKA/glutamate-bound GluN1/GluN2A agonist binding domains with UCM-101 Deposited 2025-03-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 402–539（138 aa）
Chain B 661–802（142 aa）
Not recorded DK1 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID × 1 A1B7E N-(cyclohexylmethyl)-2-[(5-{[(1R)-1-phenylpropyl]amino}-1,3,4-thiadiazol-2-yl)sulfanyl]acetamide × 1 GLU GLUTAMIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；ammonium acetate, PEG 4000
Resolution 1.71 Å R-free 0.202
9PZQ GluN1/GluN2A in complex with polyclonal autoantibody Fab fragments (class 1), glycine- and glutamate-bound state Deposited 2025-08-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain B 1–866（866 aa）
Chain D 1–866（866 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.07 Å
9PZR GluN1/GluN2A in complex with polyclonal autoantibody Fab fragments (class 2), glycine- and glutamate-bound state Deposited 2025-08-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 1–866（866 aa）
Chain D 1–866（866 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.92 Å
9PZW GluN1/GluN2A in complex with 3D2 Fab, glycine and glutamate-bound state Deposited 2025-08-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain B 1–866（866 aa）
Chain D 1–866（866 aa）
Not recorded GLY GLYCINE × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 16 GLU GLUTAMIC ACID × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.43 Å
9PZX GluN1/GluN2A in complex with 3D2 Fab, local ATD dimer Deposited 2025-08-11 Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–866（866 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.76 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.