Current Protein Identity:Q13951
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1CL3 MOLECULAR INSIGHTS INTO PEBP2/CBF-SMMHC ASSOCIATED ACUTE LEUKEMIA REVEALED FROM THE THREE-DIMENSIONAL STRUCTURE OF PEBP2/CBF BETA Deposited 1999-05-04 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
4–141(138 aa)
Fragment:BETA SUBUNIT
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7;303 K
NMR sample composition
96% WATER/4% D2O
|
Resolution not provided |
| 1E50 AML1/CBFbeta complex Deposited 2000-07-13 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
2–135(134 aa)
Fragment:HETERODIMERISATION DOMAIN RESIDUES 2-135
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.50
|
Resolution 2.60 Å R-free 0.287 |
| 1E50 AML1/CBFbeta complex Deposited 2000-07-13 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain D
2–135(134 aa)
Fragment:HETERODIMERISATION DOMAIN RESIDUES 2-135
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.50
|
Resolution 2.60 Å R-free 0.287 |
| 1E50 AML1/CBFbeta complex Deposited 2000-07-13 | Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain F
2–135(134 aa)
Fragment:HETERODIMERISATION DOMAIN RESIDUES 2-135
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.50
|
Resolution 2.60 Å R-free 0.287 |
| 1E50 AML1/CBFbeta complex Deposited 2000-07-13 | Assembly 4 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain H
2–135(134 aa)
Fragment:HETERODIMERISATION DOMAIN RESIDUES 2-135
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.50
|
Resolution 2.60 Å R-free 0.287 |
| 1H9D Aml1/cbf-beta/dna complex Deposited 2001-03-07 | Assembly 1 Protein–DNA Heteromer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers |
Chain B
2–135(134 aa)
Fragment:HETERODIMERISATION DOMAIN RESIDUES 2-135
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.50
|
Resolution 2.60 Å R-free 0.271 |
| 1H9D Aml1/cbf-beta/dna complex Deposited 2001-03-07 | Assembly 2 Protein–DNA Heteromer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers |
Chain D
2–135(134 aa)
Fragment:HETERODIMERISATION DOMAIN RESIDUES 2-135
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;pH 6.50
|
Resolution 2.60 Å R-free 0.271 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain a
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 10 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain 6
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 11 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain k
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 12 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain N
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 2 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain F
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 3 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain L
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 4 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain R
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 5 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain c
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 6 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain i
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 7 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain o
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 8 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain u
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 4N9F Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Deposited 2013-10-21 | Assembly 9 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain 0
1–170(170 aa)
Fragment:UNP residues 1-170
|
Not recorded | ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;277 K;0.22M potassium sulfate, 18% (w/v) polyethylene glycol (PEG) 3350, 100mM Tris HCl, pH 8.0., VAPOR DIFFUSION, HANGING DROP, temperature 277.0K
|
Resolution 3.30 Å R-free 0.324 |
| 6NIL cryoEM structure of the truncated HIV-1 Vif/CBFbeta/A3F complex Deposited 2018-12-29 | Assembly 1 Insufficient information Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count |
Chain B
1–151(151 aa)
Chain E
1–151(151 aa)
Chain H
1–151(151 aa)
Chain K
1–151(151 aa)
|
Not recorded | ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å |
| 6P59 Crystal structure of SIVrcm Vif-CBFbeta-ELOB-ELOC complex Deposited 2019-05-29 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
1–165(165 aa)
|
Not recorded | ZN ZINC ION × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;MES (pH 6), PEG 6000, Dichloromethane
|
Resolution 2.94 Å R-free 0.268 |
| 6P59 Crystal structure of SIVrcm Vif-CBFbeta-ELOB-ELOC complex Deposited 2019-05-29 | Assembly 2 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–165(165 aa)
|
Not recorded | ZN ZINC ION × 1 GOL GLYCEROL × 1 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;MES (pH 6), PEG 6000, Dichloromethane
|
Resolution 2.94 Å R-free 0.268 |
| 6VGD Crystal structure of the DNA binding domain (DBD) of human FLI1 and the complex of the DBD of human Runx2 with core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC Deposited 2020-01-07 | Assembly 1 Protein–DNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain G
1–142(142 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;294 K;0.6 M K/Na Tartrate, 0.1 M Hepes, pH7.0
|
Resolution 4.20 Å R-free 0.293 |
| 6VGE Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC Deposited 2020-01-07 | Assembly 1 Protein–DNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain G
1–142(142 aa)
Fragment:DNA binding domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;294 K;0.6 M K/Na Tartrate, 0.1 M Hepes, pH7.0
|
Resolution 4.25 Å R-free 0.317 |
| 6VGG Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC Deposited 2020-01-08 | Assembly 1 Protein–DNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain G
1–142(142 aa)
|
Not recorded | QWP mithramycin × 2 MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;294 K;0.3 M K/Na Tartrate, 50 mM Hepes, pH 7.0, soaked in 1 mM mithramycin-Mg
|
Resolution 4.31 Å R-free 0.285 |
| 8CX0 Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC monomeric complex Deposited 2022-05-19 | Assembly 1 Protein–RNA Heteromer;Protein × 5 PDB declaration: hexameric(6) Consistent with all polymers |
Chain C
1–182(182 aa)
|
Not recorded | ZN ZINC ION × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.70 Å |
| 8CX1 Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 1 Deposited 2022-05-19 | Assembly 1 Protein–RNA Heteromer;Protein × 10 PDB declaration: dodecameric(12) Consistent with all polymers |
Chain C
1–182(182 aa)
Chain H
1–182(182 aa)
|
Not recorded | ZN ZINC ION × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å |
| 8CX2 Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 2 Deposited 2022-05-19 | Assembly 1 Protein–RNA Heteromer;Protein × 10 PDB declaration: dodecameric(12) Consistent with all polymers |
Chain C
1–182(182 aa)
Chain H
1–182(182 aa)
|
Not recorded | ZN ZINC ION × 6 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 8E40 Full-length APOBEC3G in complex with HIV-1 Vif, CBF-beta, and fork RNA Deposited 2022-08-17 | Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain C
1–157(157 aa)
Fragment:UNP residues 1-157
|
Not recorded | ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.57 Å |
| 8FVI Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5 Deposited 2023-01-19 | Assembly 1 Protein–RNA Heteromer;Protein × 6 PDB declaration: octameric(8) Consistent with all polymers |
Chain 0
1–157(157 aa)
Fragment:UNP residues 1-157
|
Not recorded | ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.24 Å |
| 8FVJ Dimeric form of HIV-1 Vif in complex with human CBF-beta, ELOB, ELOC, and CUL5 Deposited 2023-01-19 | Assembly 1 Protein heterocomplex Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count |
Chain 0
1–157(157 aa)
Fragment:UNP residues 1-157
Chain 5
1–157(157 aa)
Fragment:UNP residues 1-157
|
Not recorded | ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.54 Å |
| 8H0I Cryo-EM structure of APOBEC3G-Vif complex Deposited 2022-09-29 | Assembly 1 Protein–RNA Heteromer;Protein × 10 PDB declaration: dodecameric(12) Consistent with all polymers |
Chain D
1–156(156 aa)
Chain F
1–156(156 aa)
Chain H
1–156(156 aa)
Chain J
1–156(156 aa)
|
Not recorded | ZN ZINC ION × 4 CL CHLORIDE ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.80 Å |
| 8J62 Cryo-EM structure of APOBEC3G-Vif complex Deposited 2023-04-24 | Assembly 1 Protein–RNA Heteromer;Protein × 10 PDB declaration: dodecameric(12) Consistent with all polymers |
Chain D
1–156(156 aa)
Chain F
1–156(156 aa)
Chain H
1–156(156 aa)
Chain J
1–156(156 aa)
|
Not recorded | ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.50 Å |
| 8SZK The cryo-EM structure of PPP2R5A/HIV-1 Vif/CBFb/EloB/EloC complex Deposited 2023-05-30 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain C
1–187(187 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.58 Å |
| 9E93 Structural Insights into HIV-1 Vif-Mediated Ubiquitination and Degradation of APOBEC3H Deposited 2024-11-07 | Assembly 1 Protein–RNA Heteromer;Protein × 6 PDB declaration: decameric(10) Consistent with all polymers |
Chain o
1–170(170 aa)
Chain s
1–170(170 aa)
|
Not recorded | ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.58 Å |
| 9E9V Structural Insights into HIV-1 Vif-Mediated Ubiquitination and Degradation of APOBEC3H Deposited 2024-11-08 | Assembly 1 Protein–RNA Heteromer;Protein × 9 PDB declaration: 13-meric(13) Consistent with all polymers |
Chain o
1–170(170 aa)
Chain s
1–170(170 aa)
|
Not recorded | ZN ZINC ION × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.00 Å |