Current Protein Identity:Q75QN2
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 7CUN The structure of human Integrator-PP2A complex Deposited 2020-08-23 | Assembly 1 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count |
Chain H
1–995(995 aa)
|
Not recorded | ZN ZINC ION × 2 MN MANGANESE (II) ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å |
| 7PKS Structural basis of Integrator-mediated transcription regulation Deposited 2021-08-26 | Assembly 1 Other combination Heteromer;Protein × 30 PDB declaration: 31-meric(31) Review required |
Chain h
1–995(995 aa)
|
Not recorded | MG MAGNESIUM ION × 1 ZN ZINC ION × 10 MN MANGANESE (II) ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å |
| 7YCX The structure of INTAC-PEC complex Deposited 2022-07-02 | Assembly 1 Other combination Heteromer;Protein × 31 PDB declaration: 34-meric(34) Consistent with all polymers |
Chain H
1–995(995 aa)
|
Not recorded | ZN ZINC ION × 10 MN MANGANESE (II) ION × 2 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.18 Å |
| 8RBX Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex Deposited 2023-12-05 | Assembly 1 Other combination Heteromer;Protein × 43 PDB declaration: 46-meric(46) Consistent with all polymers |
Chain h
1–995(995 aa)
|
Not recorded | ZN ZINC ION × 10 MG MAGNESIUM ION × 1 MN MANGANESE (II) ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.10 Å |
| 8RBZ Structure of Integrator-PP2A-SOSS-CTD post-termination complex Deposited 2023-12-05 | Assembly 1 Protein heterocomplex Heteromer;Protein × 21 PDB declaration: 21-meric(21) Consistent with protein count |
Chain h
1–995(995 aa)
|
Not recorded | ZN ZINC ION × 2 MN MANGANESE (II) ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.70 Å |
| 8RC4 Structure of Integrator-PP2A complex Deposited 2023-12-06 | Assembly 1 Protein heterocomplex Heteromer;Protein × 16 PDB declaration: 16-meric(16) Consistent with protein count |
Chain h
1–995(995 aa)
|
Not recorded | MN MANGANESE (II) ION × 2 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å |
| 8YJB Cryo-EM structure of the human DSS1-INTAC complex Deposited 2024-03-01 | Assembly 1 Protein heterocomplex Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count |
Chain H
1–995(995 aa)
|
Not recorded | ZN ZINC ION × 2 MN MANGANESE (II) ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.10 Å |
| 9EOF Structure of the human INTS5/8/10/15 subcomplex Deposited 2024-03-14 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain F
1–995(995 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 7.70 Å |
| 9EP4 Structure of Integrator subcomplex INTS5/8/15 Deposited 2024-03-17 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
1–995(995 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 9VD9 Cryo-EM structure of the human DSS1-INTAC-PEC complex Deposited 2025-06-07 | Assembly 1 Insufficient information Heteromer;Protein × 35 PDB declaration: 38-meric(38) Consistent with all polymers |
Chain H
1–995(995 aa)
|
Not recorded | ZN ZINC ION × 10 MN MANGANESE (II) ION × 2 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.60 Å |