Current Protein Identity:Q8IYB3 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1MP1 Solution structure of the PWI motif from SRm160 Deposited 2002-09-11 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 27–134(108 aa) Fragment:PWI motif (residues 27-134)
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7;298 K;Ionic strength (raw mmCIF value) 300mM NaCl, 25mM phosphate buffer;Pressure ambient
NMR sample composition 1.4mM PWI_motif U-15N,13C, 300mM NaCl, 25 mM phosphate buffer, 1mM DTT, 1mM inhibitor cocktail | 90% H20, 10%D2O
Resolution not provided
6FF4 human Bact spliceosome core structure Deposited 2018-01-03 Assembly 1 Protein–RNA Heteromer;Protein × 24 PDB declaration: 28-meric(28) Consistent with all polymers
Chain Y 1–904(904 aa)
Not recorded MG MAGNESIUM ION × 4 IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 ZN ZINC ION × 10 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE;blot with blotting sensor
Resolution 3.40 Å
6FF7 human Bact spliceosome core structure Deposited 2018-01-03 Assembly 1 Protein–RNA Heteromer;Protein × 57 PDB declaration: 61-meric(61) Consistent with all polymers
Chain Y 1–904(904 aa)
Not recorded ZN ZINC ION × 11 MG MAGNESIUM ION × 5 IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.50 Å
7ABG Human pre-Bact-1 spliceosome Deposited 2020-09-07 Assembly 1 Protein–RNA Heteromer;Protein × 54 PDB declaration: 58-meric(58) Consistent with all polymers
Chain Y 1–904(904 aa)
Not recorded IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 GTG 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.80 Å
7ABH Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) Deposited 2020-09-07 Assembly 1 Protein–RNA Heteromer;Protein × 14 PDB declaration: hexadecameric(16) Consistent with all polymers
Chain Y 1–904(904 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.50 Å
7ABI Human pre-Bact-2 spliceosome Deposited 2020-09-07 Assembly 1 Protein–RNA Heteromer;Protein × 52 PDB declaration: 56-meric(56) Consistent with all polymers
Chain Y 1–904(904 aa)
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 IHP INOSITOL HEXAKISPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 8.00 Å
7DVQ Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) Deposited 2021-01-14 Assembly 1 Protein–RNA Heteromer;Protein × 45 PDB declaration: 49-meric(49) Consistent with all polymers
Chain 8 1–904(904 aa)
Not recorded IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 5 K POTASSIUM ION × 2 G5J 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine × 1 ZN ZINC ION × 7 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.89 Å
8I0P The cryo-EM structure of human pre-Bact complex Deposited 2023-01-11 Assembly 1 Protein–RNA Heteromer;Protein × 47 PDB declaration: 51-meric(51) Consistent with all polymers
Chain 8 1–904(904 aa)
Not recorded GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 ZN ZINC ION × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.40 Å
8I0R The cryo-EM structure of human Bact-I complex Deposited 2023-01-11 Assembly 1 Protein–RNA Heteromer;Protein × 51 PDB declaration: 55-meric(55) Consistent with all polymers
Chain 8 1–904(904 aa)
Not recorded IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 6 ZN ZINC ION × 7 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.00 Å