7abi

Human pre-Bact-2 spliceosome

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

U5 small nuclear ribonucleoprotein 40 kDa protein

OrganismNot specified

UniProt Q96DI7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNR40_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain D; PDBConstruct 1–357; UniProt 1–357

Splicing factor 3B subunit 3

OrganismNot specified

UniProt Q15393

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B3_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain E; PDBConstruct 1–1217; UniProt 1–1217

Small nuclear ribonucleoprotein F

OrganismNot specified

UniProt P62306

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXF_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain b; PDBConstruct 1–86; UniProt 1–86 Author chain i; PDBConstruct 1–86; UniProt 1–86

;U2 small nuclear ribonucleoprotein A' ;

OrganismNot specified

UniProt P09661

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RU2A_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain W; PDBConstruct 1–255; UniProt 1–255

Splicing factor 3B subunit 4

OrganismNot specified

UniProt Q15427

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B4_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain w; PDBConstruct 1–424; UniProt 1–424

Small nuclear ribonucleoprotein G

OrganismNot specified

UniProt P62308

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXG_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain d; PDBConstruct 1–76; UniProt 1–76 Author chain k; PDBConstruct 1–76; UniProt 1–76

Intron-binding protein aquarius

OrganismNot specified

UniProt O60306

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name AQR_HUMAN
Isoform —
PDB entities 7
Chains and sequence ranges Author chain U; PDBConstruct 1–1485; UniProt 1–1485

Splicing factor 3B subunit 5

OrganismNot specified

UniProt Q9BWJ5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B5_HUMAN
Isoform —
PDB entities 8
Chains and sequence ranges Author chain x; PDBConstruct 1–86; UniProt 1–86

;U2 small nuclear ribonucleoprotein B'' ;

OrganismNot specified

UniProt P08579

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RU2B_HUMAN
Isoform —
PDB entities 10
Chains and sequence ranges Author chain B; PDBConstruct 1–225; UniProt 1–225

Splicing factor 3B subunit 6

OrganismNot specified

UniProt Q9Y3B4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B6_HUMAN
Isoform —
PDB entities 11
Chains and sequence ranges Author chain z; PDBConstruct 1–125; UniProt 1–125

Ubiquitin-like protein 5

OrganismNot specified

UniProt Q9BZL1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name UBL5_HUMAN
Isoform —
PDB entities 12
Chains and sequence ranges Author chain q; PDBConstruct 1–73; UniProt 1–73

U5 small nuclear ribonucleoprotein 200 kDa helicase

OrganismNot specified

UniProt O75643

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name U520_HUMAN
Isoform —
PDB entities 13
Chains and sequence ranges Author chain s; PDBConstruct 1–2136; UniProt 1–2136

SNW domain-containing protein 1

OrganismNot specified

UniProt Q13573

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNW1_HUMAN
Isoform —
PDB entities 14
Chains and sequence ranges Author chain v; PDBConstruct 1–536; UniProt 1–536

BUD13 homolog

OrganismNot specified

UniProt Q9BRD0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name BUD13_HUMAN
Isoform —
PDB entities 15
Chains and sequence ranges Author chain 3; PDBConstruct 1–619; UniProt 1–619

Smad nuclear-interacting protein 1

OrganismNot specified

UniProt Q8TAD8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNIP1_HUMAN
Isoform —
PDB entities 16
Chains and sequence ranges Author chain 0; PDBConstruct 1–396; UniProt 1–396

Protein BUD31 homolog

OrganismNot specified

UniProt P41223

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name BUD31_HUMAN
Isoform —
PDB entities 17
Chains and sequence ranges Author chain Q; PDBConstruct 1–144; UniProt 1–144

RNA-binding motif protein, X-linked 2

OrganismNot specified

UniProt Q9Y388

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RBMX2_HUMAN
Isoform —
PDB entities 18
Chains and sequence ranges Author chain 1; PDBConstruct 1–322; UniProt 1–322

Cell division cycle 5-like protein

OrganismNot specified

UniProt Q99459

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CDC5L_HUMAN
Isoform —
PDB entities 19
Chains and sequence ranges Author chain L; PDBConstruct 1–802; UniProt 1–802

Zinc finger matrin-type protein 2

OrganismNot specified

UniProt Q96NC0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name ZMAT2_HUMAN
Isoform —
PDB entities 20
Chains and sequence ranges Author chain N; PDBConstruct 1–199; UniProt 1–199

Beta-catenin-like protein 1

OrganismNot specified

UniProt Q8WYA6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CTBL1_HUMAN
Isoform —
PDB entities 21
Chains and sequence ranges Author chain S; PDBConstruct 1–563; UniProt 1–563

116 kDa U5 small nuclear ribonucleoprotein component

OrganismNot specified

UniProt Q15029

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name U5S1_HUMAN
Isoform —
PDB entities 22
Chains and sequence ranges Author chain r; PDBConstruct 1–972; UniProt 1–972

Spliceosome-associated protein CWC15 homolog

OrganismNot specified

UniProt Q9P013

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CWC15_HUMAN
Isoform —
PDB entities 23
Chains and sequence ranges Author chain R; PDBConstruct 1–229; UniProt 1–229

Serine/arginine repetitive matrix protein 1

OrganismNot specified

UniProt Q8IYB3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SRRM1_HUMAN
Isoform —
PDB entities 24
Chains and sequence ranges Author chain Y; PDBConstruct 1–904; UniProt 1–904

DNA/RNA-binding protein KIN17

OrganismNot specified

UniProt O60870

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name KIN17_HUMAN
Isoform —
PDB entities 25
Chains and sequence ranges Author chain 7; PDBConstruct 1–393; UniProt 1–393

Pre-mRNA-splicing factor SYF1

OrganismNot specified

UniProt Q9HCS7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SYF1_HUMAN
Isoform —
PDB entities 26
Chains and sequence ranges Author chain M; PDBConstruct 1–855; UniProt 1–855

Microfibrillar-associated protein 1

OrganismNot specified

UniProt P55081

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name MFAP1_HUMAN
Isoform —
PDB entities 27
Chains and sequence ranges Author chain K; PDBConstruct 1–439; UniProt 1–439

Crooked neck-like protein 1

OrganismNot specified

UniProt Q9BZJ0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CRNL1_HUMAN
Isoform Q9BZJ0-2
PDB entities 28
Chains and sequence ranges Author chain O; PDBConstruct 1–848; UniProt 1–848

PHD finger-like domain-containing protein 5A

OrganismNot specified

UniProt Q7RTV0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PHF5A_HUMAN
Isoform —
PDB entities 29
Chains and sequence ranges Author chain y; PDBConstruct 1–110; UniProt 1–110

Pleiotropic regulator 1

OrganismNot specified

UniProt O43660

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PLRG1_HUMAN
Isoform —
PDB entities 31
Chains and sequence ranges Author chain G; PDBConstruct 1–514; UniProt 1–514

Small nuclear ribonucleoprotein Sm D2

OrganismNot specified

UniProt P62316

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD2_HUMAN
Isoform —
PDB entities 32
Chains and sequence ranges Author chain a; PDBConstruct 1–118; UniProt 1–118 Author chain h; PDBConstruct 1–118; UniProt 1–118

Peptidyl-prolyl cis-trans isomerase E

OrganismNot specified

UniProt Q9UNP9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PPIE_HUMAN
Isoform —
PDB entities 33
Chains and sequence ranges Author chain o; PDBConstruct 1–301; UniProt 1–301

RING-type E3 ubiquitin-protein ligase PPIL2

OrganismNot specified

UniProt Q13356

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PPIL2_HUMAN
Isoform —
PDB entities 34
Chains and sequence ranges Author chain t; PDBConstruct 1–520; UniProt 1–520

;Small nuclear ribonucleoprotein-associated proteins B and B' ;

OrganismNot specified

UniProt P14678

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RSMB_HUMAN
Isoform —
PDB entities 35
Chains and sequence ranges Author chain f; PDBConstruct 1–240; UniProt 1–240 Author chain m; PDBConstruct 1–240; UniProt 1–240

Small nuclear ribonucleoprotein Sm D3

OrganismNot specified

UniProt P62318

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD3_HUMAN
Isoform —
PDB entities 37
Chains and sequence ranges Author chain e; PDBConstruct 1–126; UniProt 1–126 Author chain l; PDBConstruct 1–126; UniProt 1–126

Pre-mRNA-processing-splicing factor 8

OrganismNot specified

UniProt Q6P2Q9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP8_HUMAN
Isoform —
PDB entities 38
Chains and sequence ranges Author chain A; PDBConstruct 1–2335; UniProt 1–2335

Pre-mRNA-processing factor 17

OrganismNot specified

UniProt O60508

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP17_HUMAN
Isoform —
PDB entities 39
Chains and sequence ranges Author chain 8; PDBConstruct 1–579; UniProt 1–579

Small nuclear ribonucleoprotein E

OrganismNot specified

UniProt P62304

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXE_HUMAN
Isoform —
PDB entities 40
Chains and sequence ranges Author chain c; PDBConstruct 1–92; UniProt 1–92 Author chain j; PDBConstruct 1–92; UniProt 1–92

Pre-mRNA-splicing factor 38A

OrganismNot specified

UniProt Q8NAV1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PR38A_HUMAN
Isoform —
PDB entities 41
Chains and sequence ranges Author chain I; PDBConstruct 1–312; UniProt 1–312

Small nuclear ribonucleoprotein Sm D1

OrganismNot specified

UniProt P62314

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD1_HUMAN
Isoform —
PDB entities 42
Chains and sequence ranges Author chain g; PDBConstruct 1–119; UniProt 1–119 Author chain n; PDBConstruct 1–119; UniProt 1–119

Pre-mRNA-splicing factor RBM22

OrganismNot specified

UniProt Q9NW64

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RBM22_HUMAN
Isoform —
PDB entities 43
Chains and sequence ranges Author chain P; PDBConstruct 1–420; UniProt 1–420

Splicing factor 3A subunit 1

OrganismNot specified

UniProt Q15459

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A1_HUMAN
Isoform —
PDB entities 45
Chains and sequence ranges Author chain p; PDBConstruct 1–793; UniProt 1–793

Splicing factor 3A subunit 2

OrganismNot specified

UniProt Q15428

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A2_HUMAN
Isoform —
PDB entities 46
Chains and sequence ranges Author chain F; PDBConstruct 1–464; UniProt 1–464

Splicing factor 3A subunit 3

OrganismNot specified

UniProt Q12874

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A3_HUMAN
Isoform —
PDB entities 47
Chains and sequence ranges Author chain 4; PDBConstruct 1–501; UniProt 1–501

Splicing factor 3B subunit 1

OrganismNot specified

UniProt O75533

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B1_HUMAN
Isoform —
PDB entities 48
Chains and sequence ranges Author chain u; PDBConstruct 1–1304; UniProt 1–1304

Splicing factor 3B subunit 2

OrganismNot specified

UniProt Q13435

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 52 RNA 4 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Splicing factor 3B subunit 3 × 1 (Q15393) Small nuclear ribonucleoprotein F × 2 (P62306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Small nuclear ribonucleoprotein G × 2 (P62308) Intron-binding protein aquarius × 1 (O60306) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) U6 snRNA × 1 ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Ubiquitin-like protein 5 × 1 (Q9BZL1) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) SNW domain-containing protein 1 × 1 (Q13573) BUD13 homolog × 1 (Q9BRD0) Smad nuclear-interacting protein 1 × 1 (Q8TAD8) Protein BUD31 homolog × 1 (P41223) RNA-binding motif protein, X-linked 2 × 1 (Q9Y388) Cell division cycle 5-like protein × 1 (Q99459) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Beta-catenin-like protein 1 × 1 (Q8WYA6) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 1 × 1 (Q8IYB3) DNA/RNA-binding protein KIN17 × 1 (O60870) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Microfibrillar-associated protein 1 × 1 (P55081) Crooked neck-like protein 1 × 1 (Q9BZJ0) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) U2 snRNA × 1 Pleiotropic regulator 1 × 1 (O43660) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) MINX M3 pre-mRNA × 1 Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) Pre-mRNA-processing factor 17 × 1 (O60508) Small nuclear ribonucleoprotein E × 2 (P62304) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 1 × 1 (O75533) GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 1 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B2_HUMAN
Isoform —
PDB entities 49
Chains and sequence ranges Author chain T; PDBConstruct 1–895; UniProt 1–895

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7abi
Deposition date deposition_date2020-09-07
Structure title titleHuman pre-Bact-2 spliceosome
Keywords keywordsComplex, spliceosome, catalytic activation, splicing; SPLICING
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7abi__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7abi__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7abi__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)0.00 Å
Rg (electron density)104.10 Å
Total Rg104.00 Å
Atom count85564
Residues15599
Excluded volume1374300 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7abi__assembly_1__model_1 56-meric (56) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (52)

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7. Citations (1)