6qdv

Human post-catalytic P complex spliceosome

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Eukaryotic initiation factor 4A-III, N-terminally processed

OrganismNot specified

UniProt P38919

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name IF4A3_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain 7; PDBConstruct 1–390; UniProt 22–411

RNA-binding protein 8A

OrganismNot specified

UniProt Q9Y5S9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RBM8A_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain 8; PDBConstruct 1–91; UniProt 64–154

Protein mago nashi homolog 2

OrganismNot specified

UniProt Q96A72

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name MGN2_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain 9; PDBConstruct 1–144; UniProt 5–148

Pre-mRNA-processing-splicing factor 8

OrganismNot specified

UniProt Q6P2Q9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP8_HUMAN
Isoform —
PDB entities 7
Chains and sequence ranges Author chain A; PDBConstruct 1–2335; UniProt 1–2335

U5 small nuclear ribonucleoprotein 200 kDa helicase

OrganismNot specified

UniProt O75643

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name U520_HUMAN
Isoform —
PDB entities 8
Chains and sequence ranges Author chain B; PDBConstruct 1–1722; UniProt 404–2125

116 kDa U5 small nuclear ribonucleoprotein component

OrganismNot specified

UniProt Q15029

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name U5S1_HUMAN
Isoform —
PDB entities 9
Chains and sequence ranges Author chain C; PDBConstruct 1–899; UniProt 56–955

PRKR-interacting protein 1

OrganismNot specified

UniProt Q9H875

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PKRI1_HUMAN
Isoform —
PDB entities 10
Chains and sequence ranges Author chain D; PDBConstruct 1–123; UniProt 20–142

Cactin

OrganismNot specified

UniProt Q8WUQ7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CATIN_HUMAN
Isoform —
PDB entities 12
Chains and sequence ranges Author chain F; PDBConstruct 1–122; UniProt 648–769

Protein FAM32A

OrganismNot specified

UniProt Q9Y421

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name FA32A_HUMAN
Isoform —
PDB entities 13
Chains and sequence ranges Author chain G; PDBConstruct 1–60; UniProt 54–113

Pre-mRNA-splicing factor CWC22 homolog

OrganismNot specified

UniProt Q9HCG8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CWC22_HUMAN
Isoform —
PDB entities 14
Chains and sequence ranges Author chain H; PDBConstruct 1–908; UniProt 1–908

Pleiotropic regulator 1

OrganismNot specified

UniProt O43660

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PLRG1_HUMAN
Isoform —
PDB entities 16
Chains and sequence ranges Author chain J; PDBConstruct 1–320; UniProt 185–504

SNW domain-containing protein 1

OrganismNot specified

UniProt Q13573

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNW1_HUMAN
Isoform —
PDB entities 17
Chains and sequence ranges Author chain K; PDBConstruct 1–295; UniProt 41–335

Protein BUD31 homolog

OrganismNot specified

UniProt P41223

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name BUD31_HUMAN
Isoform —
PDB entities 18
Chains and sequence ranges Author chain L; PDBConstruct 1–144; UniProt 1–144

Pre-mRNA-splicing factor RBM22

OrganismNot specified

UniProt Q9NW64

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RBM22_HUMAN
Isoform —
PDB entities 19
Chains and sequence ranges Author chain M; PDBConstruct 1–289; UniProt 19–307

U5 small nuclear ribonucleoprotein 40 kDa protein

OrganismNot specified

UniProt Q96DI7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNR40_HUMAN
Isoform —
PDB entities 20
Chains and sequence ranges Author chain N; PDBConstruct 1–306; UniProt 51–357

Cell division cycle 5-like protein

OrganismNot specified

UniProt Q99459

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CDC5L_HUMAN
Isoform —
PDB entities 21
Chains and sequence ranges Author chain O; PDBConstruct 1–802; UniProt 1–802

Spliceosome-associated protein CWC15 homolog

OrganismNot specified

UniProt Q9P013

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CWC15_HUMAN
Isoform —
PDB entities 22
Chains and sequence ranges Author chain P; PDBConstruct 1–229; UniProt 1–229

Serine/arginine repetitive matrix protein 2

OrganismNot specified

UniProt Q9UQ35

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SRRM2_HUMAN
Isoform —
PDB entities 23
Chains and sequence ranges Author chain R; PDBConstruct 1–26; UniProt 1–26

Crooked neck-like protein 1

OrganismNot specified

UniProt Q9BZJ0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CRNL1_HUMAN
Isoform —
PDB entities 24
Chains and sequence ranges Author chain S; PDBConstruct 1–848; UniProt 1–848

Pre-mRNA-splicing factor SYF1

OrganismNot specified

UniProt Q9HCS7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SYF1_HUMAN
Isoform —
PDB entities 25
Chains and sequence ranges Author chain T; PDBConstruct 1–855; UniProt 1–855

Intron-binding protein aquarius

OrganismNot specified

UniProt O60306

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name AQR_HUMAN
Isoform —
PDB entities 26
Chains and sequence ranges Author chain U; PDBConstruct 1–1485; UniProt 1–1485

ATP-dependent RNA helicase DHX8

Homo sapiens

UniProt Q14562

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DHX8_HUMAN
Isoform —
PDB entities 27
Chains and sequence ranges Author chain V; PDBConstruct 1–1220; UniProt 1–1220

;U2 small nuclear ribonucleoprotein A' ;

OrganismNot specified

UniProt P09661

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RU2A_HUMAN
Isoform —
PDB entities 28
Chains and sequence ranges Author chain W; PDBConstruct 1–162; UniProt 2–163

;U2 small nuclear ribonucleoprotein B'' ;

OrganismNot specified

UniProt P08579

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RU2B_HUMAN
Isoform —
PDB entities 29
Chains and sequence ranges Author chain Y; PDBConstruct 1–92; UniProt 4–95

NF-kappa-B-activating protein

OrganismNot specified

UniProt Q8N5F7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NKAP_HUMAN
Isoform —
PDB entities 30
Chains and sequence ranges Author chain Z; PDBConstruct 1–30; UniProt 329–358

;Small nuclear ribonucleoprotein-associated proteins B and B' ;

OrganismNot specified

UniProt P14678

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RSMB_HUMAN
Isoform —
PDB entities 31
Chains and sequence ranges Author chain b; PDBConstruct 1–82; UniProt 6–87 Author chain k; PDBConstruct 1–82; UniProt 6–87

Pre-mRNA-splicing factor SLU7

OrganismNot specified

UniProt O95391

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SLU7_HUMAN
Isoform —
PDB entities 32
Chains and sequence ranges Author chain c; PDBConstruct 1–586; UniProt 1–586

Small nuclear ribonucleoprotein Sm D3

OrganismNot specified

UniProt P62318

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD3_HUMAN
Isoform —
PDB entities 33
Chains and sequence ranges Author chain d; PDBConstruct 1–84; UniProt 3–86 Author chain n; PDBConstruct 1–84; UniProt 3–86

Small nuclear ribonucleoprotein E

OrganismNot specified

UniProt P62304

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXE_HUMAN
Isoform —
PDB entities 34
Chains and sequence ranges Author chain e; PDBConstruct 1–81; UniProt 12–92 Author chain p; PDBConstruct 1–81; UniProt 12–92

Small nuclear ribonucleoprotein F

OrganismNot specified

UniProt P62306

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXF_HUMAN
Isoform —
PDB entities 35
Chains and sequence ranges Author chain f; PDBConstruct 1–72; UniProt 4–75 Author chain q; PDBConstruct 1–72; UniProt 4–75

Small nuclear ribonucleoprotein G

OrganismNot specified

UniProt P62308

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXG_HUMAN
Isoform —
PDB entities 36
Chains and sequence ranges Author chain g; PDBConstruct 1–73; UniProt 4–76 Author chain r; PDBConstruct 1–73; UniProt 4–76

Small nuclear ribonucleoprotein Sm D1

OrganismNot specified

UniProt P62314

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD1_HUMAN
Isoform —
PDB entities 37
Chains and sequence ranges Author chain h; PDBConstruct 1–80; UniProt 1–80 Author chain l; PDBConstruct 1–80; UniProt 1–80

Peptidyl-prolyl cis-trans isomerase-like 1

OrganismNot specified

UniProt Q9Y3C6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PPIL1_HUMAN
Isoform —
PDB entities 38
Chains and sequence ranges Author chain i; PDBConstruct 1–164; UniProt 3–166

Small nuclear ribonucleoprotein Sm D2

OrganismNot specified

UniProt P62316

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD2_HUMAN
Isoform —
PDB entities 39
Chains and sequence ranges Author chain j; PDBConstruct 1–118; UniProt 1–118 Author chain m; PDBConstruct 1–118; UniProt 1–118

Pre-mRNA-processing factor 17

OrganismNot specified

UniProt O60508

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP17_HUMAN
Isoform —
PDB entities 40
Chains and sequence ranges Author chain o; PDBConstruct 1–513; UniProt 69–581

Pre-mRNA-splicing factor SPF27

OrganismNot specified

UniProt O75934

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SPF27_HUMAN
Isoform —
PDB entities 41
Chains and sequence ranges Author chain s; PDBConstruct 1–225; UniProt 1–225

Pre-mRNA-processing factor 19

OrganismNot specified

UniProt Q9UMS4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-splicing factor SYF2 × 1 (O95926) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP19_HUMAN
Isoform —
PDB entities 42
Chains and sequence ranges Author chain t; PDBConstruct 1–504; UniProt 1–504 Author chain u; PDBConstruct 1–504; UniProt 1–504 Author chain v; PDBConstruct 1–504; UniProt 1–504 Author chain w; PDBConstruct 1–504; UniProt 1–504

Pre-mRNA-splicing factor SYF2

OrganismNot specified

UniProt O95926

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Replication stress response regulator SDE2 × 1 (Q6IQ49) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SYF2_HUMAN
Isoform —
PDB entities 43
Chains and sequence ranges Author chain y; PDBConstruct 1–144; UniProt 100–243

Replication stress response regulator SDE2

OrganismNot specified

UniProt Q6IQ49

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 49 RNA 5 U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Eukaryotic initiation factor 4A-III, N-terminally processed × 1 (P38919) RNA-binding protein 8A × 1 (Q9Y5S9) Protein mago nashi homolog 2 × 1 (Q96A72) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) PRKR-interacting protein 1 × 1 (Q9H875) Ligated exons: MINX mRNA × 1 Cactin × 1 (Q8WUQ7) Protein FAM32A × 1 (Q9Y421) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Intron lariat: MINX RNA × 1 Pleiotropic regulator 1 × 1 (O43660) SNW domain-containing protein 1 × 1 (Q13573) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) Crooked neck-like protein 1 × 1 (Q9BZJ0) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) Intron-binding protein aquarius × 1 (O60306) ATP-dependent RNA helicase DHX8 × 1 (Q14562) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) NF-kappa-B-activating protein × 1 (Q8N5F7) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Pre-mRNA-splicing factor SLU7 × 1 (O95391) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Pre-mRNA-splicing factor SYF2 × 1 (O95926) MAGNESIUM ION × 7 POTASSIUM ION × 1 ADENOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 7 INOSITOL HEXAKISPHOSPHATE × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SDE2_HUMAN
Isoform —
PDB entities 44
Chains and sequence ranges Author chain z; PDBConstruct 1–34; UniProt 95–128

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6qdv
Deposition date deposition_date2019-01-03
Structure title titleHuman post-catalytic P complex spliceosome
Keywords keywordsspliceosome, RNA, complex, SPLICING; SPLICING
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6qdv__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6qdv__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6qdv__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)0.00 Å
Rg (electron density)102.70 Å
Total Rg102.40 Å
Atom count121129
Residues14957
Excluded volume2117500 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6qdv__assembly_1__model_1 54-meric (54) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (50)

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7. Citations (1)