9r8v

Cryo-EM structure of the human pre-Bact-OTS complex (whole map)

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

U5 small nuclear ribonucleoprotein 200 kDa helicase

OrganismNot specified

UniProt O75643

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name U520_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 1–2136; UniProt 1–2136

Splicing factor 3A subunit 1

OrganismNot specified

UniProt Q15459

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A1_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain 7; PDBConstruct 1–793; UniProt 1–793

Cell division cycle 5-like protein

OrganismNot specified

UniProt Q99459

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CDC5L_HUMAN
Isoform —
PDB entities 7
Chains and sequence ranges Author chain L; PDBConstruct 1–802; UniProt 1–802

116 kDa U5 small nuclear ribonucleoprotein component

OrganismNot specified

UniProt Q15029

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name U5S1_HUMAN
Isoform —
PDB entities 8
Chains and sequence ranges Author chain C; PDBConstruct 1–972; UniProt 1–972

U5 small nuclear ribonucleoprotein 40 kDa protein

OrganismNot specified

UniProt Q96DI7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNR40_HUMAN
Isoform —
PDB entities 9
Chains and sequence ranges Author chain E; PDBConstruct 1–357; UniProt 1–357

Pleiotropic regulator 1

OrganismNot specified

UniProt O43660

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PLRG1_HUMAN
Isoform —
PDB entities 10
Chains and sequence ranges Author chain G; PDBConstruct 1–514; UniProt 1–514

Pre-mRNA-splicing factor 38A

OrganismNot specified

UniProt Q8NAV1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PR38A_HUMAN
Isoform —
PDB entities 11
Chains and sequence ranges Author chain I; PDBConstruct 1–312; UniProt 1–312

Protein BUD31 homolog

OrganismNot specified

UniProt P41223

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name BUD31_HUMAN
Isoform —
PDB entities 12
Chains and sequence ranges Author chain Q; PDBConstruct 1–144; UniProt 1–144

Spliceosome-associated protein CWC15 homolog

OrganismNot specified

UniProt Q9P013

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CWC15_HUMAN
Isoform —
PDB entities 13
Chains and sequence ranges Author chain R; PDBConstruct 1–229; UniProt 1–229

WW domain-binding protein 11

OrganismNot specified

UniProt Q9Y2W2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name WBP11_HUMAN
Isoform —
PDB entities 14
Chains and sequence ranges Author chain X; PDBConstruct 1–641; UniProt 1–641

Ubiquitin-like protein 5

OrganismNot specified

UniProt Q9BZL1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name UBL5_HUMAN
Isoform —
PDB entities 15
Chains and sequence ranges Author chain q; PDBConstruct 1–73; UniProt 1–73

Zinc finger matrin-type protein 2

OrganismNot specified

UniProt Q96NC0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name ZMAT2_HUMAN
Isoform —
PDB entities 16
Chains and sequence ranges Author chain r; PDBConstruct 1–199; UniProt 1–199

Small nuclear ribonucleoprotein Sm D2

OrganismNot specified

UniProt P62316

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD2_HUMAN
Isoform —
PDB entities 17
Chains and sequence ranges Author chain 22; PDBConstruct 1–118; UniProt 1–118 Author chain 52; PDBConstruct 1–118; UniProt 1–118

;U2 small nuclear ribonucleoprotein B'' ;

OrganismNot specified

UniProt P08579

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RU2B_HUMAN
Isoform —
PDB entities 18
Chains and sequence ranges Author chain 2B; PDBConstruct 1–225; UniProt 1–225

Small nuclear ribonucleoprotein F

OrganismNot specified

UniProt P62306

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXF_HUMAN
Isoform —
PDB entities 19
Chains and sequence ranges Author chain 2f; PDBConstruct 1–86; UniProt 1–86 Author chain 5f; PDBConstruct 1–86; UniProt 1–86

;Small nuclear ribonucleoprotein-associated proteins B and B' ;

OrganismNot specified

UniProt P14678

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RSMB_HUMAN
Isoform —
PDB entities 20
Chains and sequence ranges Author chain 2b; PDBConstruct 1–240; UniProt 1–240 Author chain 5b; PDBConstruct 1–240; UniProt 1–240

Small nuclear ribonucleoprotein Sm D3

OrganismNot specified

UniProt P62318

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD3_HUMAN
Isoform —
PDB entities 21
Chains and sequence ranges Author chain 23; PDBConstruct 1–126; UniProt 1–126 Author chain 53; PDBConstruct 1–126; UniProt 1–126

Small nuclear ribonucleoprotein G

OrganismNot specified

UniProt P62308

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXG_HUMAN
Isoform —
PDB entities 22
Chains and sequence ranges Author chain 2g; PDBConstruct 1–76; UniProt 1–76 Author chain 5g; PDBConstruct 1–76; UniProt 1–76

Small nuclear ribonucleoprotein E

OrganismNot specified

UniProt P62304

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXE_HUMAN
Isoform —
PDB entities 23
Chains and sequence ranges Author chain 2e; PDBConstruct 1–92; UniProt 1–92 Author chain 5e; PDBConstruct 1–92; UniProt 1–92

Small nuclear ribonucleoprotein Sm D1

OrganismNot specified

UniProt P62314

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD1_HUMAN
Isoform —
PDB entities 24
Chains and sequence ranges Author chain 21; PDBConstruct 1–119; UniProt 1–119 Author chain 51; PDBConstruct 1–119; UniProt 1–119

;U2 small nuclear ribonucleoprotein A' ;

OrganismNot specified

UniProt P09661

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RU2A_HUMAN
Isoform —
PDB entities 25
Chains and sequence ranges Author chain 2A; PDBConstruct 1–255; UniProt 1–255

Splicing factor 3B subunit 4

OrganismNot specified

UniProt Q15427

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B4_HUMAN
Isoform —
PDB entities 26
Chains and sequence ranges Author chain B4; PDBConstruct 1–424; UniProt 1–424

Splicing factor 3A subunit 3

OrganismNot specified

UniProt Q12874

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A3_HUMAN
Isoform —
PDB entities 27
Chains and sequence ranges Author chain 9; PDBConstruct 1–501; UniProt 1–501

Splicing factor 3A subunit 2

OrganismNot specified

UniProt Q15428

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A2_HUMAN
Isoform —
PDB entities 28
Chains and sequence ranges Author chain 8; PDBConstruct 1–464; UniProt 1–464

Splicing factor 3B subunit 2

OrganismNot specified

UniProt Q13435

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B2_HUMAN
Isoform —
PDB entities 29
Chains and sequence ranges Author chain B2; PDBConstruct 1–895; UniProt 1–895

Splicing factor 3B subunit 5

OrganismNot specified

UniProt Q9BWJ5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B5_HUMAN
Isoform —
PDB entities 30
Chains and sequence ranges Author chain B5; PDBConstruct 1–86; UniProt 1–86

Splicing factor 3B subunit 3

OrganismNot specified

UniProt Q15393

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B3_HUMAN
Isoform —
PDB entities 31
Chains and sequence ranges Author chain B3; PDBConstruct 1–1217; UniProt 1–1217

Splicing factor 3B subunit 1

OrganismNot specified

UniProt O75533

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B1_HUMAN
Isoform —
PDB entities 32
Chains and sequence ranges Author chain B1; PDBConstruct 1–1304; UniProt 1–1304

Splicing factor 3B subunit 6

OrganismNot specified

UniProt Q9Y3B4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B6_HUMAN
Isoform —
PDB entities 33
Chains and sequence ranges Author chain B6; PDBConstruct 1–125; UniProt 1–125

Beta-catenin-like protein 1

OrganismNot specified

UniProt Q8WYA6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CTBL1_HUMAN
Isoform —
PDB entities 34
Chains and sequence ranges Author chain BL; PDBConstruct 1–563; UniProt 1–563

U2 snRNP-associated SURP motif-containing protein

OrganismNot specified

UniProt O15042

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SR140_HUMAN
Isoform —
PDB entities 35
Chains and sequence ranges Author chain SR; PDBConstruct 1–1029; UniProt 1–1029

ATP-dependent RNA helicase DHX15

OrganismNot specified

UniProt O43143

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DHX15_HUMAN
Isoform —
PDB entities 36
Chains and sequence ranges Author chain DH; PDBConstruct 1–795; UniProt 1–795

Protein Red

OrganismNot specified

UniProt Q13123

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RED_HUMAN
Isoform —
PDB entities 38
Chains and sequence ranges Author chain x; PDBConstruct 1–557; UniProt 1–557 Author chain y; PDBConstruct 1–557; UniProt 1–557

WD40 repeat-containing protein SMU1

OrganismNot specified

UniProt Q2TAY7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMU1_HUMAN
Isoform —
PDB entities 39
Chains and sequence ranges Author chain v; PDBConstruct 1–513; UniProt 1–513 Author chain w; PDBConstruct 1–513; UniProt 1–513

RING-type E3 ubiquitin-protein ligase PPIL2

OrganismNot specified

UniProt Q13356

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PPIL2_HUMAN
Isoform —
PDB entities 41
Chains and sequence ranges Author chain t; PDBConstruct 1–520; UniProt 1–520

U6 snRNA-associated Sm-like protein LSm2

OrganismNot specified

UniProt Q9Y333

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM2_HUMAN
Isoform —
PDB entities 42
Chains and sequence ranges Author chain 62; PDBConstruct 1–95; UniProt 1–95

U6 snRNA-associated Sm-like protein LSm3

OrganismNot specified

UniProt P62310

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM3_HUMAN
Isoform —
PDB entities 43
Chains and sequence ranges Author chain 63; PDBConstruct 1–102; UniProt 1–102

U6 snRNA-associated Sm-like protein LSm4

OrganismNot specified

UniProt Q9Y4Z0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM4_HUMAN
Isoform —
PDB entities 44
Chains and sequence ranges Author chain 64; PDBConstruct 1–139; UniProt 1–139

U6 snRNA-associated Sm-like protein LSm5

OrganismNot specified

UniProt Q9Y4Y9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM5_HUMAN
Isoform —
PDB entities 45
Chains and sequence ranges Author chain 65; PDBConstruct 1–91; UniProt 1–91

U6 snRNA-associated Sm-like protein LSm6

OrganismNot specified

UniProt P62312

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM6_HUMAN
Isoform —
PDB entities 46
Chains and sequence ranges Author chain 66; PDBConstruct 1–80; UniProt 1–80

U6 snRNA-associated Sm-like protein LSm7

OrganismNot specified

UniProt Q9UK45

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM7_HUMAN
Isoform —
PDB entities 47
Chains and sequence ranges Author chain 67; PDBConstruct 1–103; UniProt 1–103

U6 snRNA-associated Sm-like protein LSm8

OrganismNot specified

UniProt O95777

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LSM8_HUMAN
Isoform —
PDB entities 48
Chains and sequence ranges Author chain 68; PDBConstruct 1–96; UniProt 1–96

SNW domain-containing protein 1

OrganismNot specified

UniProt Q13573

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNW1_HUMAN
Isoform —
PDB entities 49
Chains and sequence ranges Author chain S1; PDBConstruct 1–536; UniProt 1–536

Serine/arginine-rich splicing factor 1

OrganismNot specified

UniProt Q07955

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SRSF1_HUMAN
Isoform —
PDB entities 50
Chains and sequence ranges Author chain A6; PDBConstruct 1–248; UniProt 1–248

Transcription elongation regulator 1

OrganismNot specified

UniProt O14776

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TCRG1_HUMAN
Isoform —
PDB entities 51
Chains and sequence ranges Author chain T; PDBConstruct 1–1098; UniProt 1–1098

Microfibrillar-associated protein 1

OrganismNot specified

UniProt P55081

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Pre-mRNA-processing factor 17 × 1 (O60508) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name MFAP1_HUMAN
Isoform —
PDB entities 52
Chains and sequence ranges Author chain K; PDBConstruct 1–439; UniProt 1–439

Pre-mRNA-processing factor 17

OrganismNot specified

UniProt O60508

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP17_HUMAN
Isoform —
PDB entities 53
Chains and sequence ranges Author chain P7; PDBConstruct 1–579; UniProt 1–579

PHD finger-like domain-containing protein 5A

OrganismNot specified

UniProt Q7RTV0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 59 RNA 4 Pre-mRNA-processing-splicing factor 8 × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) U2 snRNA × 1 U6 snRNA × 1 Splicing factor 3A subunit 1 × 1 (Q15459) U5 snRNA × 1 Cell division cycle 5-like protein × 1 (Q99459) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Pleiotropic regulator 1 × 1 (O43660) Pre-mRNA-splicing factor 38A × 1 (Q8NAV1) Protein BUD31 homolog × 1 (P41223) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) WW domain-binding protein 11 × 1 (Q9Y2W2) Ubiquitin-like protein 5 × 1 (Q9BZL1) Zinc finger matrin-type protein 2 × 1 (Q96NC0) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Small nuclear ribonucleoprotein F × 2 (P62306) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein G × 2 (P62308) Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 3 × 1 (Q12874) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 6 × 1 (Q9Y3B4) Beta-catenin-like protein 1 × 1 (Q8WYA6) U2 snRNP-associated SURP motif-containing protein × 1 (O15042) ATP-dependent RNA helicase DHX15 × 1 (O43143) pre-mRNA × 1 Protein Red × 2 (Q13123) WD40 repeat-containing protein SMU1 × 2 (Q2TAY7) Pre-mRNA-splicing factor RBM22 × 1 RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) U6 snRNA-associated Sm-like protein LSm2 × 1 (Q9Y333) U6 snRNA-associated Sm-like protein LSm3 × 1 (P62310) U6 snRNA-associated Sm-like protein LSm4 × 1 (Q9Y4Z0) U6 snRNA-associated Sm-like protein LSm5 × 1 (Q9Y4Y9) U6 snRNA-associated Sm-like protein LSm6 × 1 (P62312) U6 snRNA-associated Sm-like protein LSm7 × 1 (Q9UK45) U6 snRNA-associated Sm-like protein LSm8 × 1 (O95777) SNW domain-containing protein 1 × 1 (Q13573) Serine/arginine-rich splicing factor 1 × 1 (Q07955) Transcription elongation regulator 1 × 1 (O14776) Microfibrillar-associated protein 1 × 1 (P55081) Pre-mRNA-processing factor 17 × 1 (O60508) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PHF5A_HUMAN
Isoform —
PDB entities 54
Chains and sequence ranges Author chain 5A; PDBConstruct 1–110; UniProt 1–110

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9r8v
Deposition date deposition_date2025-05-17
Structure title titleCryo-EM structure of the human pre-Bact-OTS complex (whole map)
Keywords keywordsspliceosome, SPLICING; SPLICING
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9r8v__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9r8v__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9r8v__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)0.00 Å
Rg (electron density)109.50 Å
Total Rg109.40 Å
Atom count80636
Residues14985
Excluded volume1291900 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9r8v__assembly_1__model_1 63-meric (63) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (54)

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7. Citations (1)