8ch6

Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Small nuclear ribonucleoprotein E

OrganismNot specified

UniProt P62304

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXE_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain 1; PDBConstruct 1–92; UniProt 1–92 Author chain i; PDBConstruct 1–92; UniProt 1–92

Small nuclear ribonucleoprotein F

OrganismNot specified

UniProt P62306

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXF_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain 2; PDBConstruct 1–86; UniProt 1–86 Author chain h; PDBConstruct 1–86; UniProt 1–86

Small nuclear ribonucleoprotein Sm D3

OrganismNot specified

UniProt P62318

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD3_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain 3; PDBConstruct 1–126; UniProt 1–126 Author chain j; PDBConstruct 1–126; UniProt 1–126

Small nuclear ribonucleoprotein Sm D2

OrganismNot specified

UniProt P62316

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD2_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain 4; PDBConstruct 1–118; UniProt 1–118 Author chain l; PDBConstruct 1–118; UniProt 1–118

Small nuclear ribonucleoprotein Sm D1

OrganismNot specified

UniProt P62314

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SMD1_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain 5; PDBConstruct 1–119; UniProt 1–119 Author chain k; PDBConstruct 1–119; UniProt 1–119

;Small nuclear ribonucleoprotein-associated proteins B and B' ;

OrganismNot specified

UniProt P14678

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RSMB_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain 8; PDBConstruct 1–240; UniProt 1–240 Author chain n; PDBConstruct 1–240; UniProt 1–240

Small nuclear ribonucleoprotein G

OrganismNot specified

UniProt P62308

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RUXG_HUMAN
Isoform —
PDB entities 7
Chains and sequence ranges Author chain 9; PDBConstruct 1–76; UniProt 1–76 Author chain m; PDBConstruct 1–76; UniProt 1–76

Splicing factor 3B subunit 3

OrganismNot specified

UniProt Q15393

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B3_HUMAN
Isoform —
PDB entities 8
Chains and sequence ranges Author chain A; PDBConstruct 1–1217; UniProt 1–1217

Splicing factor 3B subunit 5

OrganismNot specified

UniProt Q9BWJ5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B5_HUMAN
Isoform —
PDB entities 9
Chains and sequence ranges Author chain B; PDBConstruct 1–86; UniProt 1–86

Splicing factor 3B subunit 1

OrganismNot specified

UniProt O75533

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B1_HUMAN
Isoform —
PDB entities 10
Chains and sequence ranges Author chain C; PDBConstruct 1–1304; UniProt 1–1304

PHD finger-like domain-containing protein 5A

OrganismNot specified

UniProt Q7RTV0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PHF5A_HUMAN
Isoform —
PDB entities 11
Chains and sequence ranges Author chain D; PDBConstruct 1–110; UniProt 1–110

Splicing factor 3B subunit 2

OrganismNot specified

UniProt Q13435

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B2_HUMAN
Isoform —
PDB entities 12
Chains and sequence ranges Author chain E; PDBConstruct 1–895; UniProt 1–895

Splicing factor 3B subunit 4

OrganismNot specified

UniProt Q15427

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3B4_HUMAN
Isoform —
PDB entities 13
Chains and sequence ranges Author chain F; PDBConstruct 1–424; UniProt 1–424

G-patch domain and KOW motifs-containing protein

OrganismNot specified

UniProt Q92917

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name GPKOW_HUMAN
Isoform —
PDB entities 14
Chains and sequence ranges Author chain G; PDBConstruct 1–476; UniProt 1–476

Splicing factor 3A subunit 1

OrganismNot specified

UniProt Q15459

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A1_HUMAN
Isoform —
PDB entities 15
Chains and sequence ranges Author chain H; PDBConstruct 1–793; UniProt 1–793

Splicing factor 3A subunit 2

OrganismNot specified

UniProt Q15428

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A2_HUMAN
Isoform —
PDB entities 16
Chains and sequence ranges Author chain I; PDBConstruct 1–464; UniProt 1–464

Splicing factor 3A subunit 3

OrganismNot specified

UniProt Q12874

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SF3A3_HUMAN
Isoform —
PDB entities 17
Chains and sequence ranges Author chain J; PDBConstruct 1–501; UniProt 1–501

Pre-mRNA-processing factor 19

OrganismNot specified

UniProt Q9UMS4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP19_HUMAN
Isoform —
PDB entities 18
Chains and sequence ranges Author chain K; PDBConstruct 1–504; UniProt 1–504 Author chain M; PDBConstruct 1–504; UniProt 1–504 Author chain R; PDBConstruct 1–504; UniProt 1–504 Author chain v; PDBConstruct 1–504; UniProt 1–504

BUD13 homolog

OrganismNot specified

UniProt Q9BRD0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name BUD13_HUMAN
Isoform —
PDB entities 19
Chains and sequence ranges Author chain L; PDBConstruct 1–619; UniProt 1–619

Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

OrganismNot specified

UniProt O60231

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DHX16_HUMAN
Isoform —
PDB entities 20
Chains and sequence ranges Author chain N; PDBConstruct 1–1041; UniProt 1–1041

Pleiotropic regulator 1

OrganismNot specified

UniProt O43660

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PLRG1_HUMAN
Isoform —
PDB entities 21
Chains and sequence ranges Author chain O; PDBConstruct 1–514; UniProt 1–514

Cell division cycle 5-like protein

OrganismNot specified

UniProt Q99459

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CDC5L_HUMAN
Isoform —
PDB entities 22
Chains and sequence ranges Author chain P; PDBConstruct 1–802; UniProt 1–802

Spliceosome-associated protein CWC15 homolog

OrganismNot specified

UniProt Q9P013

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CWC15_HUMAN
Isoform —
PDB entities 23
Chains and sequence ranges Author chain Q; PDBConstruct 1–229; UniProt 1–229

Pre-mRNA-splicing factor SPF27

OrganismNot specified

UniProt O75934

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SPF27_HUMAN
Isoform —
PDB entities 24
Chains and sequence ranges Author chain S; PDBConstruct 1–225; UniProt 1–225

Protein BUD31 homolog

OrganismNot specified

UniProt P41223

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name BUD31_HUMAN
Isoform —
PDB entities 25
Chains and sequence ranges Author chain T; PDBConstruct 1–144; UniProt 1–144

Pre-mRNA-splicing factor RBM22

OrganismNot specified

UniProt Q9NW64

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RBM22_HUMAN
Isoform —
PDB entities 26
Chains and sequence ranges Author chain U; PDBConstruct 1–420; UniProt 1–420

Peptidyl-prolyl cis-trans isomerase-like 4

OrganismNot specified

UniProt Q8WUA2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PPIL4_HUMAN
Isoform —
PDB entities 27
Chains and sequence ranges Author chain V; PDBConstruct 1–492; UniProt 1–492

Pre-mRNA-splicing factor CWC22 homolog

OrganismNot specified

UniProt Q9HCG8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CWC22_HUMAN
Isoform —
PDB entities 28
Chains and sequence ranges Author chain W; PDBConstruct 1–908; UniProt 1–908

Crooked neck-like protein 1

OrganismNot specified

UniProt Q9BZJ0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CRNL1_HUMAN
Isoform Q9BZJ0-2
PDB entities 29
Chains and sequence ranges Author chain X; PDBConstruct 1–848; UniProt 1–848

SNW domain-containing protein 1

OrganismNot specified

UniProt Q13573

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNW1_HUMAN
Isoform —
PDB entities 30
Chains and sequence ranges Author chain Y; PDBConstruct 1–536; UniProt 1–536

RING finger protein 113A

OrganismNot specified

UniProt O15541

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name R113A_HUMAN
Isoform —
PDB entities 31
Chains and sequence ranges Author chain Z; PDBConstruct 1–343; UniProt 1–343

Pre-mRNA-processing-splicing factor 8

OrganismNot specified

UniProt Q6P2Q9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP8_HUMAN
Isoform —
PDB entities 32
Chains and sequence ranges Author chain a; PDBConstruct 1–2335; UniProt 1–2335

116 kDa U5 small nuclear ribonucleoprotein component

OrganismNot specified

UniProt Q15029

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name U5S1_HUMAN
Isoform —
PDB entities 33
Chains and sequence ranges Author chain b; PDBConstruct 1–972; UniProt 1–972

U5 small nuclear ribonucleoprotein 200 kDa helicase

OrganismNot specified

UniProt O75643

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name U520_HUMAN
Isoform —
PDB entities 34
Chains and sequence ranges Author chain c; PDBConstruct 1–2136; UniProt 1–2136

U5 small nuclear ribonucleoprotein 40 kDa protein

OrganismNot specified

UniProt Q96DI7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNR40_HUMAN
Isoform —
PDB entities 39
Chains and sequence ranges Author chain o; PDBConstruct 1–357; UniProt 1–357

Peptidyl-prolyl cis-trans isomerase-like 1

OrganismNot specified

UniProt Q9Y3C6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PPIL1_HUMAN
Isoform —
PDB entities 40
Chains and sequence ranges Author chain p; PDBConstruct 1–166; UniProt 1–166

Serine/arginine repetitive matrix protein 2

OrganismNot specified

UniProt Q9UQ35

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SRRM2_HUMAN
Isoform —
PDB entities 41
Chains and sequence ranges Author chain q; PDBConstruct 1–2752; UniProt 1–2752

;U2 small nuclear ribonucleoprotein A' ;

OrganismNot specified

UniProt P09661

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RU2A_HUMAN
Isoform —
PDB entities 42
Chains and sequence ranges Author chain r; PDBConstruct 1–255; UniProt 1–255

;U2 small nuclear ribonucleoprotein B'' ;

OrganismNot specified

UniProt P08579

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RU2B_HUMAN
Isoform —
PDB entities 43
Chains and sequence ranges Author chain s; PDBConstruct 1–225; UniProt 1–225

Pre-mRNA-splicing factor ISY1 homolog

OrganismNot specified

UniProt Q9ULR0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name ISY1_HUMAN
Isoform —
PDB entities 44
Chains and sequence ranges Author chain t; PDBConstruct 1–285; UniProt 1–285

RING-type E3 ubiquitin-protein ligase PPIL2

OrganismNot specified

UniProt Q13356

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PPIL2_HUMAN
Isoform —
PDB entities 45
Chains and sequence ranges Author chain u; PDBConstruct 1–520; UniProt 1–520

Peptidyl-prolyl cis-trans isomerase E

OrganismNot specified

UniProt Q9UNP9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PPIE_HUMAN
Isoform —
PDB entities 46
Chains and sequence ranges Author chain w; PDBConstruct 1–301; UniProt 1–301

Pre-mRNA-processing factor 17

OrganismNot specified

UniProt O60508

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Intron-binding protein aquarius × 1 (O60306) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PRP17_HUMAN
Isoform —
PDB entities 47
Chains and sequence ranges Author chain x; PDBConstruct 1–579; UniProt 1–579

Intron-binding protein aquarius

OrganismNot specified

UniProt O60306

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Pre-mRNA-splicing factor SYF1 × 1 (Q9HCS7) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name AQR_HUMAN
Isoform —
PDB entities 48
Chains and sequence ranges Author chain y; PDBConstruct 1–1485; UniProt 1–1485

Pre-mRNA-splicing factor SYF1

OrganismNot specified

UniProt Q9HCS7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 55 RNA 4 Small nuclear ribonucleoprotein E × 2 (P62304) Small nuclear ribonucleoprotein F × 2 (P62306) Small nuclear ribonucleoprotein Sm D3 × 2 (P62318) Small nuclear ribonucleoprotein Sm D2 × 2 (P62316) Small nuclear ribonucleoprotein Sm D1 × 2 (P62314) ;Small nuclear ribonucleoprotein-associated proteins B and B' ; × 2 (P14678) Small nuclear ribonucleoprotein G × 2 (P62308) Splicing factor 3B subunit 3 × 1 (Q15393) Splicing factor 3B subunit 5 × 1 (Q9BWJ5) Splicing factor 3B subunit 1 × 1 (O75533) PHD finger-like domain-containing protein 5A × 1 (Q7RTV0) Splicing factor 3B subunit 2 × 1 (Q13435) Splicing factor 3B subunit 4 × 1 (Q15427) G-patch domain and KOW motifs-containing protein × 1 (Q92917) Splicing factor 3A subunit 1 × 1 (Q15459) Splicing factor 3A subunit 2 × 1 (Q15428) Splicing factor 3A subunit 3 × 1 (Q12874) Pre-mRNA-processing factor 19 × 4 (Q9UMS4) BUD13 homolog × 1 (Q9BRD0) Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 × 1 (O60231) Pleiotropic regulator 1 × 1 (O43660) Cell division cycle 5-like protein × 1 (Q99459) Spliceosome-associated protein CWC15 homolog × 1 (Q9P013) Pre-mRNA-splicing factor SPF27 × 1 (O75934) Protein BUD31 homolog × 1 (P41223) Pre-mRNA-splicing factor RBM22 × 1 (Q9NW64) Peptidyl-prolyl cis-trans isomerase-like 4 × 1 (Q8WUA2) Pre-mRNA-splicing factor CWC22 homolog × 1 (Q9HCG8) Crooked neck-like protein 1 × 1 (Q9BZJ0) SNW domain-containing protein 1 × 1 (Q13573) RING finger protein 113A × 1 (O15541) Pre-mRNA-processing-splicing factor 8 × 1 (Q6P2Q9) 116 kDa U5 small nuclear ribonucleoprotein component × 1 (Q15029) U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 (O75643) RNU6-1 × 1 RNU5A-1 × 1 RNU2-1 × 1 MINX-M3 × 1 U5 small nuclear ribonucleoprotein 40 kDa protein × 1 (Q96DI7) Peptidyl-prolyl cis-trans isomerase-like 1 × 1 (Q9Y3C6) Serine/arginine repetitive matrix protein 2 × 1 (Q9UQ35) ;U2 small nuclear ribonucleoprotein A' ; × 1 (P09661) ;U2 small nuclear ribonucleoprotein B'' ; × 1 (P08579) Pre-mRNA-splicing factor ISY1 homolog × 1 (Q9ULR0) RING-type E3 ubiquitin-protein ligase PPIL2 × 1 (Q13356) Peptidyl-prolyl cis-trans isomerase E × 1 (Q9UNP9) Pre-mRNA-processing factor 17 × 1 (O60508) Intron-binding protein aquarius × 1 (O60306) ZINC ION × 12 INOSITOL HEXAKISPHOSPHATE × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 MAGNESIUM ION × 7 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SYF1_HUMAN
Isoform —
PDB entities 49
Chains and sequence ranges Author chain z; PDBConstruct 1–855; UniProt 1–855

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8ch6
Deposition date deposition_date2023-02-07
Structure title titleStructure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).
Keywords keywordsactivated spliceosome, Aquarius, PRP2, SPLICING; SPLICING
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8ch6__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8ch6__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8ch6__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)0.00 Å
Rg (electron density)100.80 Å
Total Rg100.30 Å
Atom count119058
Residues17326
Excluded volume2022100 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8ch6__assembly_1__model_1 59-meric (59) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (53)

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7. Citations (1)