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10rb

Human SARM1 TIR domain bound to compound 14

Method: X-RAY DIFFRACTION Dmax: 66.3 Å Quality: EXCELLENT

SAXS Profile

SAXS profile for 10rb

P(r) Distribution

P(r) distribution for 10rb

1. Structure Basics

entry_id10rb
deposition_date2026-02-02
titleHuman SARM1 TIR domain bound to compound 14
keywordsHydrolase, inhibitor, adduct, NAD; HYDROLASE
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier21.23
rg_electron20.46
i036697800.00
molecular_weight31434.0 kDa
excluded_volume30486 ų
envelope_volume50240 ų
shell_volume20704 ų
envelope_diameter69.5
shell_rg26.50
envelope_rg20.56
shape_rg20.40
total_rg21.16
total_atoms2378
n_residues280
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax66.3
rg_real21.19
rg_real_error0.34
i0_real3.6700e+07
i0_real_error4.4180e+05
rg_reciprocal21.20
i0_reciprocal36700000.0000
total_estimate0.9049
solution_quality EXCELLENT a EXCELLENT solution
n_peaks2
r_peak_primary23.4
skewness0.292
kurtosis-0.521
angular_range— – 0.3750 −1
current_alpha0.0000
highest_alpha11230000.0000
n_real_points69
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.926; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.996; Smooth: 0.985

4. Crystallography & Experiment

5. Entities & Polymer Info (3)

6. Citations (1)

7. Files & Curves (10)