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10rc

Human SARM1 TIR domain bound to compound 22

Method: X-RAY DIFFRACTION Dmax: 66.0 Å Quality: GOOD

SAXS Profile

SAXS profile for 10rc

P(r) Distribution

P(r) distribution for 10rc

1. Structure Basics

entry_id10rc
deposition_date2026-02-02
titleHuman SARM1 TIR domain bound to compound 22
keywordsHydrolase, inhibitor, adduct, NAD; HYDROLASE
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier21.30
rg_electron20.51
i037388700.00
molecular_weight31670.0 kDa
excluded_volume30705 ų
envelope_volume50923 ų
shell_volume20890 ų
envelope_diameter69.0
shell_rg26.49
envelope_rg20.60
shape_rg20.45
total_rg21.22
total_atoms2396
n_residues280
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax66.0
rg_real21.26
rg_real_error0.33
i0_real3.7390e+07
i0_real_error4.7150e+05
rg_reciprocal21.27
i0_reciprocal37390000.0000
total_estimate0.7613
solution_quality GOOD a GOOD solution
n_peaks2
r_peak_primary23.3
skewness0.289
kurtosis-0.516
angular_range— – 0.3750 −1
current_alpha0.0000
highest_alpha11700000.0000
n_real_points69
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.934; Stabil: 1.000; Sysdev: 0.368; Positv: 1.000; Valcen: 0.998; Smooth: 0.989

4. Crystallography & Experiment

5. Entities & Polymer Info (4)

6. Citations (1)

7. Files & Curves (10)