Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants.
J.Med.Chem. (1999)
;Crystallographic Analysis of the Binding Modes of Thiazoloisoindolinone Non-nucleoside Inhibitors to HIV-1 Reverse Transcriptase and Comparison with Modelling Studies
;
J.Med.Chem. (1999)
Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives
Biochemistry (1998)
;3'-azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes
;
Proc.Natl.Acad.Sci.USA (1998)
Continuous and discontinuous changes in the unit cell of HIV-1 reverse transcriptase crystals on dehydration
Acta Crystallogr.,Sect.D (1998)
;Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this non-nucleoside inhibitor
;
Proc.Natl.Acad.Sci.USA (1997)
;Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors
;
J.Med.Chem. (1996)
The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design
Structure (1995)
High Resolution Structures of HIV-1 RT From Four RT-inhibitor Complexes
Nat.Struct.Biol. (1995)
Mechanism of Inhibition of HIV-1 Reverse Transcriptase by Non-nucleoside Inhibitors
Nat.Struct.Biol. (1995)
Crystals of HIV-1 Reverse Transcriptase Diffracting to 2.2 Angstrom Resolution
J.Mol.Biol. (1994)
