;Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
;
J.Biol.Chem. (2000)
;Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies.
;
J.Med.Chem. (1999)
Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants.
J.Med.Chem. (1999)
Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.
Biochemistry (1998)
;3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes.
;
Proc.Natl.Acad.Sci.USA (1998)
Continuous and discontinuous changes in the unit cell of HIV-1 reverse transcriptase crystals on dehydration.
Acta Crystallogr.,Sect.D (1998)
;Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor.
;
Proc.Natl.Acad.Sci.USA (1997)
;Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors.
;
J.Med.Chem. (1996)
Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors.
Nat.Struct.Biol. (1995)
The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design.
Structure (1995)
High resolution structures of HIV-1 RT from four RT-inhibitor complexes.
Nat.Struct.Biol. (1995)
Crystals of HIV-1 reverse transcriptase diffracting to 2.2 A resolution.
J.Mol.Biol. (1994)
