1i7x
BETA-CATENIN/E-CADHERIN COMPLEX
SAXS 散射曲线 SAXS Profile
P(r) 距离分布 P(r) Distribution
1. 结构基本信息 1. Structure Basics
| 条目编号 entry_id | 1i7x |
| 沉积日期 deposition_date | 2001-03-10 |
| 结构标题 title | BETA-CATENIN/E-CADHERIN COMPLEX |
| 关键词 keywords | E-cadherin, cell adhesion, beta-catenin, protein-protein complex, extended interface, armadillo repeat; CELL ADHESION |
| 实验方法 method | X-RAY DIFFRACTION |
2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)
| 回转半径 Rg (Guinier) rg_guinier | 42.95 Å |
| 回转半径 Rg (电子) rg_electron | 43.23 Å |
| 零角强度 I(0) i0 | 245840000.00 |
| 分子量 molecular_weight | 127110.0 kDa |
| 排除体积 excluded_volume | 159260 ų |
| 包络体积 envelope_volume | 219180 ų |
| 水化壳体积 shell_volume | 46099 ų |
| 包络直径 envelope_diameter | 165.6 Å |
| 壳层 Rg shell_rg | 43.12 Å |
| 包络 Rg envelope_rg | 43.30 Å |
| 形状 Rg shape_rg | 43.27 Å |
| 总 Rg total_rg | 43.10 Å |
| 总原子数 total_atoms | 8910 |
| 残基数 n_residues | 1163 |
| 球谐函数阶数 n_harmonics | 20 |
| q 范围 q_range | — – 0.5000 Å−1 |
| 数据点数 n_points | 101 |
| 壳层类型 shell_type | directional |
| 溶剂电子密度 solvent_density | 0.3340 e/ų |
| 壳层衬度 contrast_shell | 0.0300 e/ų |
| CRYSOL 版本 crysol_version | 4.1.3 |
3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)
| 最大尺寸 Dmax dmax | 154.7 Å |
| Rg (实空间) rg_real | 43.47 Å |
| Rg 误差 (实空间) rg_real_error | 1.82 Å |
| I(0) (实空间) i0_real | 2.4580e+08 |
| I(0) 误差 (实空间) i0_real_error | 4.8200e+06 |
| Rg (倒空间) rg_reciprocal | 42.95 Å |
| I(0) (倒空间) i0_reciprocal | 245700000.0000 |
| 解质量估计 total_estimate | 0.5824 |
| 解质量评级 solution_quality | REASONABLE a REASONABLE solution |
| P(r) 峰数 n_peaks | 2 |
| 主峰位置 r_peak_primary | 50.2 Å |
| 偏度 Skewness skewness | 0.662 |
| 峰度 Kurtosis kurtosis | 0.084 |
| 角度范围 angular_range | — – 0.1850 Å−1 |
| 当前正则化参数 α current_alpha | 0.0000 |
| 最高正则化参数 α highest_alpha | 11950000.0000 |
| 实空间数据点数 n_real_points | 38 |
| GNOM 版本 gnom_version | 4.1.3 |
| 质量判据 quality_criteria | AN1: 0.000; Oscil: 0.666; Stabil: 1.000; Sysdev: 0.083; Positv: 1.000; Valcen: 0.776; Smooth: 0.544 |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合体信息 (3)
6. 折叠分类 (SCOP + CATH) 7 domains
SCOP 2.08 (4 domains)
| 结构域编号 domain_id | d1i7xa_ |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.1 — ARM repeat |
| 家族 Family family | a.118.1.1 — Armadillo repeat |
| 结构域编号 domain_id | d1i7xb_ |
| 类 Class class | j — Peptides |
| 折叠类型 Fold fold | j.71 — beta-Catenine bound non-globular protein regions |
| 超家族 Superfamily superfamily | j.71.1 — beta-Catenine bound non-globular protein regions |
| 家族 Family family | j.71.1.1 — beta-Catenine bound non-globular protein regions |
| 结构域编号 domain_id | d1i7xc_ |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.1 — ARM repeat |
| 家族 Family family | a.118.1.1 — Armadillo repeat |
| 结构域编号 domain_id | d1i7xd_ |
| 类 Class class | j — Peptides |
| 折叠类型 Fold fold | j.71 — beta-Catenine bound non-globular protein regions |
| 超家族 Superfamily superfamily | j.71.1 — beta-Catenine bound non-globular protein regions |
| 家族 Family family | j.71.1.1 — beta-Catenine bound non-globular protein regions |
CATH v4.4 (3 domains)
| 结构域编号 domain_id | 1i7xA00 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 10 — Leucine-rich Repeat Variant |
| 同源超家族 H-superfamily homologous superfamily | 10 — Leucine-rich Repeat Variant |
| 结构域编号 domain_id | 1i7xC00 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 10 — Leucine-rich Repeat Variant |
| 同源超家族 H-superfamily homologous superfamily | 10 — Leucine-rich Repeat Variant |
| 结构域编号 domain_id | 1i7xD00 |
| 类 Class class | 4 — Few Secondary Structures |
| 架构 Architecture architecture | 10 — Irregular |
| 拓扑 Topology topology | 900 — TCF3-CBD (Catenin binding domain) |
| 同源超家族 H-superfamily homologous superfamily | 10 — TCF3-CBD (Catenin binding domain) |