1nu9

Staphylocoagulase-Prethrombin-2 complex

Method: X-RAY DIFFRACTION Dmax: 152.1 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 1nu9

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1nu9
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1nu9
沉积日期 deposition_date2003-01-31
结构标题 titleStaphylocoagulase-Prethrombin-2 complex
关键词 keywordsThrombin non-proteolytic activator, endocarditis, hydrolase-hydrolase inhibitor complex, protein binding; HYDROLASE/HYDROLASE INHIBITOR
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier45.79
回转半径 Rg (电子) rg_electron46.16
零角强度 I(0) i0533385000.00
分子量 molecular_weight125630.0 kDa
排除体积 excluded_volume120630 ų
包络体积 envelope_volume243560 ų
水化壳体积 shell_volume45871 ų
包络直径 envelope_diameter152.8
壳层 Rg shell_rg48.48
包络 Rg envelope_rg44.73
形状 Rg shape_rg46.25
总 Rg total_rg46.09
总原子数 total_atoms9460
残基数 n_residues1052
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax152.1
Rg (实空间) rg_real46.21
Rg 误差 (实空间) rg_real_error1.55
I(0) (实空间) i0_real5.3340e+08
I(0) 误差 (实空间) i0_real_error9.4660e+06
Rg (倒空间) rg_reciprocal45.80
I(0) (倒空间) i0_reciprocal533100000.0000
解质量估计 total_estimate0.7728
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks2
主峰位置 r_peak_primary31.3
偏度 Skewness skewness0.343
峰度 Kurtosis kurtosis-0.942
角度范围 angular_range— – 0.1700 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha21510000.0000
实空间数据点数 n_real_points35
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.525; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.671; Smooth: 0.796

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (6)

6. 折叠分类 (SCOP + CATH) 14 domains

SCOP 2.08 (6 domains)

结构域编号 domain_idd1nu9a_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.2 — Eukaryotic proteases
结构域编号 domain_idd1nu9c1
类 Class classa — All alpha proteins
折叠类型 Fold folda.8 — immunoglobulin/albumin-binding domain-like
超家族 Superfamily superfamilya.8.6 — Staphylocoagulase
家族 Family familya.8.6.1 — Staphylocoagulase
结构域编号 domain_idd1nu9c2
类 Class classa — All alpha proteins
折叠类型 Fold folda.8 — immunoglobulin/albumin-binding domain-like
超家族 Superfamily superfamilya.8.6 — Staphylocoagulase
家族 Family familya.8.6.1 — Staphylocoagulase
结构域编号 domain_idd1nu9d_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.2 — Eukaryotic proteases
结构域编号 domain_idd1nu9f1
类 Class classa — All alpha proteins
折叠类型 Fold folda.8 — immunoglobulin/albumin-binding domain-like
超家族 Superfamily superfamilya.8.6 — Staphylocoagulase
家族 Family familya.8.6.1 — Staphylocoagulase
结构域编号 domain_idd1nu9f2
类 Class classa — All alpha proteins
折叠类型 Fold folda.8 — immunoglobulin/albumin-binding domain-like
超家族 Superfamily superfamilya.8.6 — Staphylocoagulase
家族 Family familya.8.6.1 — Staphylocoagulase

CATH v4.4 (8 domains)

结构域编号 domain_id1nu9A01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id1nu9A02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id1nu9C01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
同源超家族 H-superfamily homologous superfamily750 — Staphylcoagulase, helix bundle domain 1
结构域编号 domain_id1nu9C02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
同源超家族 H-superfamily homologous superfamily760 — Staphylcoagulase, helix bundle, domain 2
结构域编号 domain_id1nu9D01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id1nu9D02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id1nu9F01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
同源超家族 H-superfamily homologous superfamily750 — Staphylcoagulase, helix bundle domain 1
结构域编号 domain_id1nu9F02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
同源超家族 H-superfamily homologous superfamily760 — Staphylcoagulase, helix bundle, domain 2

7. 引用文献 (1)

8. 文件与曲线 (10)