HOMO SAPIENS
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | GUANOSINE-5'-DIPHOSPHATE × 1 water × 1 | Consistent with protein count |
| UniProt name | RASH_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–166； UniProt 1–166 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 2x1v |
| Deposition date deposition_date | 2010-01-04 |
| Structure title title | Crystal Structure of the activating H-Ras I163F mutant in Costello Syndrome, bound to MG-GDP |
| Keywords keywords | ;S-NITROSYLATION, DISEASE MUTATION, PALMITATE, HYDROLASE, METHYLATION, PRENYLATION, CELL MEMBRANE, PROTO-ONCOGENE, GTPASE PROTEIN, GOLGI APPARATUS ;; HYDROLASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 15.68 Å |
| Rg (electron density) | 14.25 Å |
| Total Rg | 15.38 Å |
| Atom count | 1113 |
| Residues | 139 |
| Excluded volume | 19610 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d2x1va_ |
| Class class | c — Alpha and beta proteins (a/b) |
| Fold Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| Superfamily Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| Family Family family | c.37.1.8 — G proteins |
| Domain ID domain_id | 2x1vA00 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| Topology topology | 50 — Rossmann fold |
| Homologous superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |