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3epc

CryoEM structure of poliovirus receptor bound to poliovirus type 1

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Poliovirus receptor

Homo sapiens

UniProt P15151

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 300 Protein VP1 × 60 （P03300） Protein VP2 × 60 （P03300） Protein VP4 × 60 （P03300） Protein VP3 × 60 （P03300） SPHINGOSINE × 60 MYRISTIC ACID × 60 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Protein VP1 × 1 （P03300） Protein VP2 × 1 （P03300） Protein VP4 × 1 （P03300） Protein VP3 × 1 （P03300） SPHINGOSINE × 1 MYRISTIC ACID × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 25 Protein VP1 × 5 （P03300） Protein VP2 × 5 （P03300） Protein VP4 × 5 （P03300） Protein VP3 × 5 （P03300） SPHINGOSINE × 5 MYRISTIC ACID × 5 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 30 Protein VP1 × 6 （P03300） Protein VP2 × 6 （P03300） Protein VP4 × 6 （P03300） Protein VP3 × 6 （P03300） SPHINGOSINE × 6 MYRISTIC ACID × 6 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 Protein VP1 × 1 （P03300） Protein VP2 × 1 （P03300） Protein VP4 × 1 （P03300） Protein VP3 × 1 （P03300） SPHINGOSINE × 1 MYRISTIC ACID × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
3uro

1 assemblies

Homodimer
3uro

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1dgi 1dgi 1dgi 1dgi 1dgi 1nn8 1nn8 1nn8 1nn8 1nn8 3epc 3epc

40 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PVR_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain R； PDBConstruct 1–213； UniProt 30–242

Protein VP1

Human poliovirus 1 Mahoney

UniProt P03300

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 300 Poliovirus receptor × 60 （P15151） SPHINGOSINE × 60 MYRISTIC ACID × 60 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Poliovirus receptor × 1 （P15151） SPHINGOSINE × 1 MYRISTIC ACID × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 25 Poliovirus receptor × 5 （P15151） SPHINGOSINE × 5 MYRISTIC ACID × 5 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 30 Poliovirus receptor × 6 （P15151） SPHINGOSINE × 6 MYRISTIC ACID × 6 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 Poliovirus receptor × 1 （P15151） SPHINGOSINE × 1 MYRISTIC ACID × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1l1n 1l1n 1ra6 1ra7 1raj 1rdr 1tql 2bbp 2ijf 2ily 2ilz 2im0

32 assemblies; showing the first 12

Homodimer
1ng7 2ijd 2ijd

3 assemblies

Homotetramer
1hxs 1hxs 2plv 2plv 5z3q

5 assemblies

Other homooligomers
1hxs 1hxs 1hxs 1hxs 1pov 1pov 1pov 1pov 1pov 1pov 1xyr 1xyr

30 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
1al2 1al2 1al2 1al2 1al2 1al2 1ar6 1ar6 1ar6 1ar6 1ar6 1ar6

181 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name POLG_POL1M
Isoform —
PDB entities 2, 3, 4, 5
Chains and sequence ranges Author chain 1； PDBConstruct 1–283； UniProt 599–881 Author chain 2； PDBConstruct 1–268； UniProt 74–341 Author chain 4； PDBConstruct 1–68； UniProt 2–69 Author chain 3； PDBConstruct 1–235； UniProt 342–576

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3epc
Deposition date deposition_date2008-09-29
Structure title titleCryoEM structure of poliovirus receptor bound to poliovirus type 1
Keywords keywords;CD155 structure Immunoglobulin Superfamily, poliovirus capsid jelly role, Cell adhesion, Cell membrane, Glycoprotein, Host-virus interaction, Immunoglobulin domain, Membrane, Receptor, Secreted, Transmembrane, VIRAL PROTEIN, VIRUS ;; VIRUS
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3epc__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3epc__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3epc__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)141.10 Å
Total Rg141.20 Å
Atom count497520
Residues63720
Excluded volume8848200 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3epc__assembly_1__model_1 300-MERIC （300） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 3epc__assembly_2__model_1 pentameric （5） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 3epc__assembly_3__model_1 25-meric （25） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 3epc__assembly_4__model_1 30-meric （30） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 3epc__assembly_5__model_1 pentameric （5） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (7)

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7. Citations (1)