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3us2

Structure of p63 DNA Binding Domain in Complex with a 19 Base Pair A/T Rich Response Element Containing Two Half Sites with a Single Base Pair Overlap

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Tumor protein 63

Homo sapiens

UniProt Q9H3D4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Homooligomer Protein 4 DNA 2 5'-D(*AP*AP*AP*CP*AP*TP*GP*TP*TP*AP*AP*AP*CP*AP*TP*GP*TP*TP*T)-3' × 1 5'-D(*AP*AP*AP*CP*AP*TP*GP*TP*TP*TP*AP*AP*CP*AP*TP*GP*TP*TP*T)-3' × 1 ZINC ION × 4 Consistent with all polymers
2 Protein–DNA Homooligomer Protein 4 DNA 2 5'-D(*AP*AP*AP*CP*AP*TP*GP*TP*TP*AP*AP*AP*CP*AP*TP*GP*TP*TP*T)-3' × 1 5'-D(*AP*AP*AP*CP*AP*TP*GP*TP*TP*TP*AP*AP*CP*AP*TP*GP*TP*TP*T)-3' × 1 ZINC ION × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
1rg6 2rmn 2y9t 2y9u

4 assemblies

Homodimer

None

Homotetramer
3zy0 3zy1 4a9z

3 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
2nb1 3qym 3qym 3qym 3qyn 3us0 3us1 3us2 3us2 6fgn 6ru6 6ru7

30 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name P63_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 7–203； UniProt 166–362 Author chain B； PDBConstruct 7–203； UniProt 166–362 Author chain C； PDBConstruct 7–203； UniProt 166–362 Author chain D； PDBConstruct 7–203； UniProt 166–362 Author chain G； PDBConstruct 7–203； UniProt 166–362 Author chain H； PDBConstruct 7–203； UniProt 166–362 Author chain I； PDBConstruct 7–203； UniProt 166–362 Author chain J； PDBConstruct 7–203； UniProt 166–362

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3us2
Deposition date deposition_date2011-11-22
Structure title titleStructure of p63 DNA Binding Domain in Complex with a 19 Base Pair A/T Rich Response Element Containing Two Half Sites with a Single Base Pair Overlap
Keywords keywordsB-DNA double helix, zinc binding, beta sandwich, Greek key, transcription factor, nucleus, TRANSCRIPTION ACTIVATOR-DNA complex; TRANSCRIPTION ACTIVATOR/DNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3us2__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3us2__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3us2__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）32.19 Å
Rg (electron density)32.85 Å
Total Rg32.96 Å
Atom count6605
Residues788
Excluded volume114710 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3us2__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 3us2__assembly_2__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)