4p9w

Structure of ConA/Rh3Man

Method: X-RAY DIFFRACTION D_max: 90.1 Å Quality: EXCELLENT

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Concanavalin-A

OrganismNot specified

State in the Current Structure

Assembly	Oligomeric State	Construct	Mutations and Modifications	Ligands, Ions and Associated Components	Method and Experimental Conditions	Structure Quality
1	Protein homooligomer Homooligomer Protein × 4 PDB declaration: tetrameric（4） Consistent with protein copy count	Chain A； UniProt 164–281 Chain A； UniProt 30–148 Chain B； UniProt 164–281 Chain B； UniProt 30–148 Chain C； UniProt 164–281 Chain C； UniProt 30–148 Chain D； UniProt 164–281 Chain D； UniProt 30–148	Fragment：UNP residues 164-281, 30-148	R3M 2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions：LIQUID DIFFUSION；pH 7.2；298 K；buffer: 20 mM HEPES, 5 mM of CaCl2, and 5 mM of MnCl2; pH = 7.2. The crystal was obtained by diffusion method in glass tube sequentially put with ConA solution, pure buffer, and the ligand solution.	Resolution 2.11 Å R-free 0.202

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB	Difference from Current Entry 4P9W	Assembly / Oligomeric State	Construct	Mutations and Modifications	Ligands, Ions and Non-polymers	Method and Experimental Conditions	Structure Quality
1APN THE CRYSTALLOGRAPHIC STRUCTURE OF METAL-FREE CONCANAVALIN A AT 2.5 ANGSTROMS RESOLUTION Deposited 1995-07-28	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–290（127 aa） Chain B 164–290（127 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.50 Å R-free 0.247
1BXH CONCANAVALIN A COMPLEXED TO METHYL ALPHA1-2 MANNOBIOSIDE Deposited 1998-10-02	Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Fragment：UNP P02866 residues 164-281, 30-148 Chain A 30–148（119 aa） Fragment：UNP P02866 residues 164-281, 30-148 Chain B 164–281（118 aa） Fragment：UNP P02866 residues 164-281, 30-148 Chain B 30–148（119 aa） Fragment：UNP P02866 residues 164-281, 30-148 Chain C 164–281（118 aa） Fragment：UNP P02866 residues 164-281, 30-148 Chain C 30–148（119 aa） Fragment：UNP P02866 residues 164-281, 30-148 Chain D 164–281（118 aa） Fragment：UNP P02866 residues 164-281, 30-148 Chain D 30–148（119 aa） Fragment：UNP P02866 residues 164-281, 30-148	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MMA methyl alpha-D-mannopyranoside × 2	X-RAY DIFFRACTION X-ray crystallization conditions pH 7；13.5% PEG 6K, 1.0M LICL, 0.1M TRIS PH 7.0	Resolution 2.75 Å R-free 0.238
1CES CRYSTALS OF DEMETALLIZED CONCANAVALIN A SOAKED WITH ZINC HAVE A ZINC ION BOUND IN THE S1 SITE Deposited 1996-02-15	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa）	Not recorded	ZN ZINC ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 5；pH 5.	Resolution 2.70 Å R-free 0.249
1CJP CONCANAVALIN A COMPLEX WITH 4'-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE Deposited 1996-10-03	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa） Chain C 30–148（119 aa） Chain D 30–148（119 aa）	Not recorded	MUG 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOSE × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.78 Å R-free 0.216
1CN1 CRYSTAL STRUCTURE OF DEMETALLIZED CONCANAVALIN A. THE METAL-BINDING REGION Deposited 1981-12-21	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 1–237（237 aa） Chain B 1–237（237 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 3.20 Å
1CON THE REFINED STRUCTURE OF CADMIUM SUBSTITUTED CONCANAVALIN A AT 2.0 ANGSTROMS RESOLUTION Deposited 1993-03-16	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa）	Not recorded	CD CADMIUM ION × 8 CA CALCIUM ION × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.00 Å
1CVN CONCANAVALIN A COMPLEXED TO TRIMANNOSIDE Deposited 1995-08-09	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa） Chain C 30–148（119 aa） Chain D 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 9；pH 9.0	Resolution 2.30 Å R-free 0.255
1DQ6 Manganese;Manganese concanavalin A at pH 7.0 Deposited 1999-12-30	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 8	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；277 K；2 M ammonium sulphate, 60 mM sodium acetate at pH 7, 3% PEGMe 5000, 1 mM MnCl2, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 277.0K	Resolution 1.90 Å
1ENQ CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH ZINC HAVING A ZINC ION BOUND IN THE S1 SITE Deposited 1996-03-20	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa） Chain C 30–148（119 aa） Chain D 30–148（119 aa）	Not recorded	ZN ZINC ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 5；pH 5.	Resolution 2.50 Å R-free 0.284
1ENR CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH ZINC AND CALCIUM HAVING A ZINC ION BOUND IN THE S1 SITE AND A CALCIUM ION BOUND IN THE S2 SITE Deposited 1996-03-20	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa）	Not recorded	CA CALCIUM ION × 4 ZN ZINC ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 7；pH 7.	Resolution 1.83 Å
1ENS CRYSTALS OF DEMETALLIZED CONCANAVALIN A SOAKED WITH COBALT HAVING A COBALT ION BOUND IN THE S1 SITE Deposited 1996-03-20	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa）	Not recorded	CO COBALT (II) ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 5；pH 5.	Resolution 2.80 Å R-free 0.259
1GIC CONCANAVALIN A COMPLEXED WITH METHYL ALPHA-D-GLUCOPYRANOSIDE Deposited 1996-08-08	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa）	Not recorded	GYP methyl alpha-D-glucopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions dialysis；pH 6.8；DIALYSIS; 5MM PROTEIN CONCENTRATION WITH, pH 6.8, dialysis	Resolution 2.00 Å
1GKB CONCANAVALIN A, NEW CRYSTAL FORM Deposited 2001-08-10	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MG MAGNESIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；HANGING DROP, 30MG/ML, 10+10 UL 1 ML WELL, TRIS/HCL PH 8.0, 25%	Resolution 1.56 Å R-free 0.206
1I3H CONCANAVALIN A-DIMANNOSE STRUCTURE Deposited 2001-02-15	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Fragment：residues 164-281,residues 30-148 Chain A 30–148（119 aa） Fragment：residues 164-281,residues 30-148	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5；298 K；PEG 6000, citirc acid, manganese chloride, calcium chloride, pH 5.0, VAPOR DIFFUSION, SITTING DROP, temperature 298K	Resolution 1.20 Å R-free 0.190
1JBC CONCANAVALIN A Deposited 1996-08-23	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 8–148（141 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 1.15 Å R-free 0.167
1JN2 Crystal Structure of meso-tetrasulphonatophenyl porphyrin complexed with Concanavalin A Deposited 2001-07-22	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain P 164–281（118 aa） Fragment：UNP P02866 residues 164-281, 30-148 Chain P 30–148（119 aa） Fragment：UNP P02866 residues 164-281, 30-148	Not recorded	CA CALCIUM ION × 1 MN MANGANESE (II) ION × 1 SFP 5,10,15,20-TETRAKIS(4-SULPFONATOPHENYL)-21H,23H-PORPHINE × 1	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 1.90 Å R-free 0.232
1JN2 Crystal Structure of meso-tetrasulphonatophenyl porphyrin complexed with Concanavalin A Deposited 2001-07-22	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 2 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain P 164–281（118 aa） Fragment：UNP P02866 residues 164-281, 30-148 Chain P 30–148（119 aa） Fragment：UNP P02866 residues 164-281, 30-148	Not recorded	CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 SFP 5,10,15,20-TETRAKIS(4-SULPFONATOPHENYL)-21H,23H-PORPHINE × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 1.90 Å R-free 0.232
1JW6 Crystal Structure of the Complex of Concanavalin A and Hexapeptide Deposited 2001-09-02	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 PTD PENTANEDIAL × 4 IPA ISOPROPYL ALCOHOL × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.45；300 K；Sodium phosphate , pH 5.45, VAPOR DIFFUSION, HANGING DROP, temperature 300.0K	Resolution 1.93 Å R-free 0.250
1JW6 Crystal Structure of the Complex of Concanavalin A and Hexapeptide Deposited 2001-09-02	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 2 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 PTD PENTANEDIAL × 4 IPA ISOPROPYL ALCOHOL × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.45；300 K；Sodium phosphate , pH 5.45, VAPOR DIFFUSION, HANGING DROP, temperature 300.0K	Resolution 1.93 Å R-free 0.250
1NLS CONCANAVALIN A AND ITS BOUND SOLVENT AT 0.94A RESOLUTION Deposited 1997-01-28	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 6.8；pH 6.8	Resolution 0.94 Å R-free 0.154
1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain 1 164–281（118 aa） Chain 1 30–148（119 aa）	Not recorded	AZI AZIDE ION × 3 MN MANGANESE (II) ION × 2 NA SODIUM ION × 1 GOL GLYCEROL × 8	X-RAY DIFFRACTION X-ray crystallization conditions Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K	Resolution 1.90 Å R-free 0.201
1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain 2 164–281（118 aa） Chain 2 30–148（119 aa）	Not recorded	AZI AZIDE ION × 5 MN MANGANESE (II) ION × 2 NA SODIUM ION × 1 GOL GLYCEROL × 6	X-RAY DIFFRACTION X-ray crystallization conditions Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K	Resolution 1.90 Å R-free 0.201
1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain 3 164–281（118 aa） Chain 3 30–148（119 aa）	Not recorded	AZI AZIDE ION × 4 MN MANGANESE (II) ION × 2 NA SODIUM ION × 1 GOL GLYCEROL × 5	X-RAY DIFFRACTION X-ray crystallization conditions Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K	Resolution 1.90 Å R-free 0.201
1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain 4 164–281（118 aa） Chain 4 30–148（119 aa）	Not recorded	AZI AZIDE ION × 4 MN MANGANESE (II) ION × 2 NA SODIUM ION × 1 GOL GLYCEROL × 6	X-RAY DIFFRACTION X-ray crystallization conditions Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K	Resolution 1.90 Å R-free 0.201
1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 5 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain 1 164–281（118 aa） Chain 1 30–148（119 aa） Chain 2 164–281（118 aa） Chain 2 30–148（119 aa）	Not recorded	AZI AZIDE ION × 16 MN MANGANESE (II) ION × 8 NA SODIUM ION × 4 GOL GLYCEROL × 28	X-RAY DIFFRACTION X-ray crystallization conditions Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K	Resolution 1.90 Å R-free 0.201
1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 6 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain 3 164–281（118 aa） Chain 3 30–148（119 aa） Chain 4 164–281（118 aa） Chain 4 30–148（119 aa）	Not recorded	AZI AZIDE ION × 16 MN MANGANESE (II) ION × 8 NA SODIUM ION × 4 GOL GLYCEROL × 22	X-RAY DIFFRACTION X-ray crystallization conditions Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K	Resolution 1.90 Å R-free 0.201
1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 7 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain 1 164–281（118 aa） Chain 1 30–148（119 aa） Chain 2 164–281（118 aa） Chain 2 30–148（119 aa）	Not recorded	AZI AZIDE ION × 8 MN MANGANESE (II) ION × 4 NA SODIUM ION × 2 GOL GLYCEROL × 14	X-RAY DIFFRACTION X-ray crystallization conditions Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K	Resolution 1.90 Å R-free 0.201
1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 8 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain 3 164–281（118 aa） Chain 3 30–148（119 aa） Chain 4 164–281（118 aa） Chain 4 30–148（119 aa）	Not recorded	AZI AZIDE ION × 8 MN MANGANESE (II) ION × 4 NA SODIUM ION × 2 GOL GLYCEROL × 11	X-RAY DIFFRACTION X-ray crystallization conditions Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K	Resolution 1.90 Å R-free 0.201
1ONA CO-CRYSTALS OF CONCANAVALIN A WITH METHYL-3,6-DI-O-(ALPHA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE Deposited 1996-07-07	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa） Chain C 30–148（119 aa） Chain D 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 6.5；13% POLYETHYLENEGLYCOLMETHYLETHER, 40 MM HEPES PH 6.5	Resolution 2.35 Å R-free 0.282
1QNY X-ray refinement of D2O soaked crystal of concanavalin A Deposited 1999-10-26	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain A 164–281（118 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 6.5；CRYSTALS SELECTED FOR X-RAY STUDY WERE TRANSFERRED TO A 1ML BUFFER MADE OF 99.9% D2O WITH 0.1M NANO3, 0.05M TRIS-ACETATE, 1MM MNCL2 AND 1MM CACL2 PH 6.5.	Resolution 1.80 Å R-free 0.198
1SCR HIGH-RESOLUTION STRUCTURES OF SINGLE-METAL-SUBSTITUTED CONCANAVALIN A: THE CO,CA-PROTEIN AT 1.6 ANGSTROMS AND THE NI,CA-PROTEIN AT 2.0 ANGSTROMS Deposited 1993-12-06	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa）	Not recorded	NI NICKEL (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.00 Å
1SCS HIGH-RESOLUTION STRUCTURES OF SINGLE-METAL-SUBSTITUTED CONCANAVALIN A: THE CO,CA-PROTEIN AT 1.6 ANGSTROMS AND THE NI,CA-PROTEIN AT 2.0 ANGSTROMS Deposited 1993-12-06	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa）	Not recorded	CO COBALT (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 1.60 Å
1TEI STRUCTURE OF CONCANAVALIN A COMPLEXED TO BETA-D-GLCNAC (1,2)ALPHA-D-MAN-(1,6)[BETA-D-GLCNAC(1,2)ALPHA-D-MAN (1,6)]ALPHA-D-MAN Deposited 1997-05-28	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa） Chain C 30–148（119 aa） Chain D 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 5.5；POLYETHYLENE GLYCOL 15%, pH 5.5	Resolution 2.70 Å R-free 0.219
1TEI STRUCTURE OF CONCANAVALIN A COMPLEXED TO BETA-D-GLCNAC (1,2)ALPHA-D-MAN-(1,6)[BETA-D-GLCNAC(1,2)ALPHA-D-MAN (1,6)]ALPHA-D-MAN Deposited 1997-05-28	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 2 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain E 30–148（119 aa） Chain F 30–148（119 aa） Chain G 30–148（119 aa） Chain H 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 5.5；POLYETHYLENE GLYCOL 15%, pH 5.5	Resolution 2.70 Å R-free 0.219
1TEI STRUCTURE OF CONCANAVALIN A COMPLEXED TO BETA-D-GLCNAC (1,2)ALPHA-D-MAN-(1,6)[BETA-D-GLCNAC(1,2)ALPHA-D-MAN (1,6)]ALPHA-D-MAN Deposited 1997-05-28	Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 3 Other combination Homooligomer；Protein × 8 PDB declaration: octameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa） Chain C 30–148（119 aa） Chain D 30–148（119 aa） Chain E 30–148（119 aa） Chain F 30–148（119 aa） Chain G 30–148（119 aa） Chain H 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 8 CA CALCIUM ION × 8	X-RAY DIFFRACTION X-ray crystallization conditions pH 5.5；POLYETHYLENE GLYCOL 15%, pH 5.5	Resolution 2.70 Å R-free 0.219
1VAL CONCANAVALIN A COMPLEX WITH 4'-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE Deposited 1996-01-08	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa） Chain C 30–148（119 aa） Chain D 30–148（119 aa）	Not recorded	PNG 4-nitrophenyl alpha-D-glucopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 3.00 Å R-free 0.274
1VAM CONCANAVALIN A COMPLEX WITH 4'-NITROPHENYL-ALPHA-D-MANNOPYRANOSIDE Deposited 1996-01-08	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa） Chain C 30–148（119 aa） Chain D 30–148（119 aa）	Not recorded	PNA 4-nitrophenyl alpha-D-mannopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.75 Å R-free 0.260
1XQN The 15k neutron structure of saccharide-free concanavalin A Deposited 2004-10-13	Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	NEUTRON DIFFRACTION X-ray crystallization conditions BATCH DIALYSIS；pH 6.5；293 K；0.1M NaNO3, 0.05M Tris-acetate, 1mM MnCl2, 1mM CaCl2 (all in D2O), pH 6.50, BATCH DIALYSIS, temperature 293.0K	Resolution 2.50 Å R-free 0.320
2CNA THE COVALENT AND THREE-DIMENSIONAL STRUCTURE OF CONCANAVALIN A, IV.ATOMIC COORDINATES,HYDROGEN BONDING,AND QUATERNARY STRUCTURE Deposited 1975-04-01	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–290（127 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.00 Å
2CTV HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF NATIVE CONCANAVALIN A USING RAPID LAUE DATA COLLECTION METHODS AND THE INTRODUCTION OF A MONOCHROMATIC LARGE-ANGLE OSCILLATION TECHNIQUE (LOT) Deposited 1993-08-10	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 1.95 Å
2ENR CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH CADMIUM HAVING A CADMIUM ION BOUND IN BOTH THE S1 SITE AND THE S2 SITE Deposited 1998-07-14	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 8–148（141 aa）	Not recorded	CD CADMIUM ION × 8	X-RAY DIFFRACTION X-ray crystallization conditions pH 5；pH 5.0	Resolution 2.35 Å
2UU8 X-ray structure of Ni, Ca concanavalin A at Ultra-high resolution (0. 94A) Deposited 2007-03-01	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	NI NICKEL (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions pH 6.5；pH 6.5	Resolution 0.94 Å R-free 0.142
2YZ4 The neutron structure of concanavalin A at 2.2 Angstroms Deposited 2007-05-02	Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	NEUTRON DIFFRACTION X-ray crystallization conditions BATCH DIALYSIS；pH 6.5；293 K；0.1M NaNO3, 0.05M Tris-acetate, 1mM MnCl2, 1mM CaCl2, pH 6.5, BATCH DIALYSIS, temperature 293K	Resolution 2.20 Å R-free 0.312
3CNA STRUCTURE OF CONCANAVALIN A AT 2.4 ANGSTROMS RESOLUTION Deposited 1976-09-15	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 1–237（237 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.40 Å
3D4K Concanavalin A Complexed to a Synthetic Analog of the Trimannoside Deposited 2008-05-14	Different construct Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 GOL GLYCEROL × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.8；291 K；10-16% PEG 6000, 100 mM Sodium cacodylate, 50 mM NaCL, 1 mM MnCL2, 1 mM CaCL2, pH 6.8, VAPOR DIFFUSION, HANGING DROP, temperature 291K	Resolution 1.80 Å R-free 0.238
3ENR ZINC-CALCIUM CONCANAVALIN A AT PH 6.15 Deposited 1999-02-11	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	ZN ZINC ION × 4 CA CALCIUM ION × 2	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.15；ZNCL2, CACL2, (NH4)2SO4, sodium acetate, pH 6.15, VAPOR DIFFUSION, SITTING DROP	Resolution 2.40 Å R-free 0.283
3NWK A second C2221 form of concanavalin A (Canavalia ensiformis) Deposited 2010-07-09	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa）	Not recorded	CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 GOL GLYCEROL × 10	X-RAY DIFFRACTION X-ray crystallization conditions hanging drop vapor diffusion using polymer-induced heteronucleation；pH 8.5；273 K；10 mM Tris, pH 8.5, 1 M ammonium sulfate, hanging drop vapor diffusion using polymer-induced heteronucleation, temperature 273K	Resolution 2.09 Å R-free 0.212
3NWK A second C2221 form of concanavalin A (Canavalia ensiformis) Deposited 2010-07-09	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 2 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 GOL GLYCEROL × 12	X-RAY DIFFRACTION X-ray crystallization conditions hanging drop vapor diffusion using polymer-induced heteronucleation；pH 8.5；273 K；10 mM Tris, pH 8.5, 1 M ammonium sulfate, hanging drop vapor diffusion using polymer-induced heteronucleation, temperature 273K	Resolution 2.09 Å R-free 0.212
3NWK A second C2221 form of concanavalin A (Canavalia ensiformis) Deposited 2010-07-09	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa）	Not recorded	CA CALCIUM ION × 2 MN MANGANESE (II) ION × 2 GOL GLYCEROL × 5	X-RAY DIFFRACTION X-ray crystallization conditions hanging drop vapor diffusion using polymer-induced heteronucleation；pH 8.5；273 K；10 mM Tris, pH 8.5, 1 M ammonium sulfate, hanging drop vapor diffusion using polymer-induced heteronucleation, temperature 273K	Resolution 2.09 Å R-free 0.212
3NWK A second C2221 form of concanavalin A (Canavalia ensiformis) Deposited 2010-07-09	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	CA CALCIUM ION × 2 MN MANGANESE (II) ION × 2 GOL GLYCEROL × 6	X-RAY DIFFRACTION X-ray crystallization conditions hanging drop vapor diffusion using polymer-induced heteronucleation；pH 8.5；273 K；10 mM Tris, pH 8.5, 1 M ammonium sulfate, hanging drop vapor diffusion using polymer-induced heteronucleation, temperature 273K	Resolution 2.09 Å R-free 0.212
4P9X Structure of ConA/Rh3Glu complex Deposited 2014-04-06	Different ligand/ion Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Fragment：UNP residues 164-281, 30-148 Chain A 30–148（119 aa） Fragment：UNP residues 164-281, 30-148 Chain B 164–281（118 aa） Fragment：UNP residues 164-281, 30-148 Chain B 30–148（119 aa） Fragment：UNP residues 164-281, 30-148 Chain C 164–281（118 aa） Fragment：UNP residues 164-281, 30-148 Chain C 30–148（119 aa） Fragment：UNP residues 164-281, 30-148 Chain D 164–281（118 aa） Fragment：UNP residues 164-281, 30-148 Chain D 30–148（119 aa） Fragment：UNP residues 164-281, 30-148	Not recorded	R3G 2-[2-(2-{4-[(alpha-D-glucopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions LIQUID DIFFUSION；pH 7.2；298 K；buffer: 20 mM HEPES, 5 mM of CaCl2, and 5 mM of MnCl2; pH = 7.2. The crystal was obtained by diffusion method in glass tube sequentially put with ConA solution, pure buffer, and the ligand solution.	Resolution 2.06 Å R-free 0.295
4P9Y Structure of ConA/Rh4man Deposited 2014-04-06	Different construct Different mutation/modification Different ligand/ion Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Fragment：UNP residues 164-281, 30-148 Chain A 30–148（119 aa） Fragment：UNP residues 164-281, 30-148 Chain B 164–281（118 aa） Fragment：UNP residues 164-281, 30-148 Chain B 30–148（119 aa） Fragment：UNP residues 164-281, 30-148	Not recorded	2KO 2-{2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethoxy}ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions LIQUID DIFFUSION；pH 7.2；298 K；buffer: 20 mM HEPES, 5 mM of CaCl2, and 5 mM of MnCl2; pH = 7.2. The crystal was obtained by diffusion method in glass tube sequentially put with ConA solution, pure buffer, and the ligand solution.	Resolution 1.89 Å R-free 0.258
4PF5 Crystal structure of Concanavalin A complexed with a synthetic derivative of high-mannose chain Deposited 2014-04-28	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: Tetrameric	Chain A 164–281（118 aa） Fragment：Residues 164-281, 30-148 Chain A 30–148（119 aa） Fragment：Residues 164-281, 30-148 Chain B 164–281（118 aa） Fragment：Residues 164-281, 30-148 Chain B 30–148（119 aa） Fragment：Residues 164-281, 30-148	Not recorded	MN MANGANESE (II) ION × 8 M3N 4-(hydroxymethyl)-1-(alpha-D-mannopyranosyl)-1H-1,2,3-triazole × 4 EDO 1,2-ETHANEDIOL × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；Sodium Acetate, 1,4-dioxane	Resolution 2.04 Å R-free 0.227
5CNA REFINED STRUCTURE OF CONCANAVALIN A COMPLEXED WITH ALPHA-METHYL-D-MANNOPYRANOSIDE AT 2.0 ANGSTROMS RESOLUTION AND COMPARISON WITH THE SACCHARIDE-FREE STRUCTURE Deposited 1994-02-11	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–148（119 aa） Chain B 30–148（119 aa） Chain C 30–148（119 aa） Chain D 30–148（119 aa）	Not recorded	MMA methyl alpha-D-mannopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 CL CHLORIDE ION × 1	X-RAY DIFFRACTION mmCIF provides none of the parsed conditions	Resolution 2.00 Å
5O6N High pressure flash cooled concanavalin A Deposited 2017-06-07	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 NA SODIUM ION × 4 CL CHLORIDE ION × 8	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；291 K；10 mg/ml Concanavalin A in 0.025 M HEPES pH 7.0 were mixed in a 1:1 ratio with 6 % (w/v) PEG 8000 and 0.1 M Tris pH 8.5.	Resolution 1.35 Å R-free 0.164
5WEY Joint X-ray/neutron structure of Concanavalin A with alpha1-2 D-mannobiose Deposited 2017-07-11	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric	Chain A 164–281（118 aa） Fragment：unp residues 164-281; unp residues 30-148 Chain A 30–148（119 aa） Fragment：unp residues 164-281; unp residues 30-148	Not recorded	MN MANGANESE (II) ION × 1 CA CALCIUM ION × 1	Experimental method not declared X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5；291 K；10% PEG 6K, 0.1 M sodium citrate, pH 5 in H2O	Resolution not provided
5YGM Monomeric structure of concanavalin A at pH 7.5 from Carnivalia ensiformis Deposited 2017-09-24	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	CA CALCIUM ION × 1 MN MANGANESE (II) ION × 1	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；PEK6K, MPD in HEPES, pH 7.5	Resolution 1.60 Å R-free 0.196
5Z5L Crystal structure of ConA-R5M Deposited 2018-01-18	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2 96O (1-methyl-1H-1,2,3-triazol-4-yl)methyl alpha-D-mannopyranoside × 1	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.2；293 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2	Resolution 2.30 Å R-free 0.277
5Z5L Crystal structure of ConA-R5M Deposited 2018-01-18	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain C 164–281（118 aa） Chain C 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.2；293 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2	Resolution 2.30 Å R-free 0.277
5Z5N Crystal structure of ConA-R1M Deposited 2018-01-18	Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 MAN alpha-D-mannopyranose × 1	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.2；300 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2 pH 7.2	Resolution 2.04 Å R-free 0.225
5Z5P Crystal structure of ConA-R3M Deposited 2018-01-19	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 2 CA CALCIUM ION × 3 R3M 2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 2	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.2；300 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2 pH 7.2	Resolution 1.40 Å R-free 0.241
5Z5Y Crystal structure of ConA-R4M Deposited 2018-01-22	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	2KO 2-{2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethoxy}ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 2 MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2 CL CHLORIDE ION × 1	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.2；300 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2 pH 7.2	Resolution 1.89 Å R-free 0.244
5Z5Y Crystal structure of ConA-R4M Deposited 2018-01-22	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 2 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	2KO 2-{2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethoxy}ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 CL CHLORIDE ION × 2	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.2；300 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2 pH 7.2	Resolution 1.89 Å R-free 0.244
5ZAC Crystal structure of ConA-R2M Deposited 2018-02-07	Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 6 MAN alpha-D-mannopyranose × 2 TA5 2H-1,2,3-TRIAZOL-4-YLMETHANOL × 2	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.2；300 K；each 0.2 mM ConA in 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2 pH 7.2	Resolution 2.59 Å R-free 0.372
6AHG Trimeric structure of concanavalin A from Canavalia ensiformis Deposited 2018-08-18	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa）	Not recorded	CA CALCIUM ION × 3 CD CADMIUM ION × 6	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293 K；Polyethylene glycol 400, 0.1 M Cadmium chloride hydrate, 0.1 M Sodium acetate trihydrate pH 4.6	Resolution 2.83 Å R-free 0.279
6H2M Long wavelength Mesh&Collect native SAD phasing on microcrystals Deposited 2018-07-13	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 1 CA CALCIUM ION × 1	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；drops made from equal amounts of protein solution (1 l, 10 mg/ml in water) and reservoir solution (1l, 34%(v/v) PEG 1500), buffered with 5mM HEPES, pH 6.0	Resolution 1.93 Å R-free 0.177
6XT6 pro-concanavalin A: Precursor of circularly permuted concanavalin A Deposited 2020-07-17	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 30–290（261 aa） Chain B 30–290（261 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 8 ZN ZINC ION × 4 EDO 1,2-ETHANEDIOL × 30	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；289 K；Zinc chloride, HEPES, PEG 6000	Resolution 2.10 Å R-free 0.244
7MG1 Concanavalin A crystallized without DNA glycoconjugate Deposited 2021-04-12	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) + 1 uL crystallization condition (Helix screen, condition H3: 0.1 M potassium chloride, 0.005 M barium chloride dihydrate, 0.05 M bis-Tris (pH 7), 12% w/v PEG 8000). Reservoir contained 70 uL of crystallization condition.	Resolution 2.00 Å R-free 0.262
7MG2 Concanavalin A crystallized in the presence of Man-8 Deposited 2021-04-12	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and mannose-squaramide (128 uM) + 1 uL crystallization condition (Helix screen, condition B6: 0.1 M sodium chloride, 0.005 M strontium chloride hexahydrate, 0.05 M MES (pH 6.5), 17% w/v PEG 4000). Reservoir contained 70 uL of crystallization condition.	Resolution 1.80 Å R-free 0.230
7MG3 Concanavalin A crystallized in the presence of H2N-ATAT Deposited 2021-04-12	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and 5'-ATAT-3' (128 uM) + 1 uL crystallization condition (Helix screen, condition D11: 0.2 M lithium chloride, 0.05 M bis-Tris (pH 7), 22% w/v PEG 2000 MME). Reservoir contained 70 uL of crystallization condition.	Resolution 1.60 Å R-free 0.213
7MG4 Concanavalin A crystallized in the presence of Gal-ATAT Deposited 2021-04-12	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and Gal-ATAT (128 uM) + 1 uL crystallization condition (Helix screen, condition H9: 0.1 M potassium chloride, 0.002 M spermine tetrahydrochloride, 0.05 M bis-Tris (pH 7.5), 7% w/v PEG 8000). Reservoir contained 70 uL of crystallization condition.	Resolution 2.00 Å R-free 0.237
7MG5 Concanavalin A bound to a DNA glycoconjugate, Man-ATAT Deposited 2021-04-12	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (40 uM) and Man-ATAT (160 uM) + 1 uL crystallization condition (Helix screen, condition D9: 0.05 M bis-Tris (pH 7), 2 M ammonium sulfate, 5% v/v PEG 400). Reservoir contained 70 uL of crystallization condition.	Resolution 2.10 Å R-free 0.245
7MG6 Concanavalin A bound to a DNA glycoconjugate, Man-AGCT Deposited 2021-04-12	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (40 uM) and Man-AGCT (160 uM) + 1 uL crystallization condition (Helix screen, condition D3: 0.2 M lithium sulfate, 0.05 M bis Tris (pH 7), 20% v/v MPD). Reservoir contained 70 uL of crystallization condition.	Resolution 1.70 Å R-free 0.207
7MG7 Concanavalin A bound to a DNA glycoconjugate, Man-GTAC Deposited 2021-04-12	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and Man-GTAC (128 uM) + 1 uL crystallization condition (Helix screen, condition A4: 0.2 M potassium chloride, 0.005 M hexammine cobalt(III) chloride, 0.05 M MES (pH 6.5), 25% v/v PEG 400). Reservoir contained 70 uL of crystallization condition	Resolution 1.75 Å R-free 0.215
7MG8 Concanavalin A bound to a DNA glycoconjugate, Man-CGCG Deposited 2021-04-12	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (80 uM) and Man-CGCG (160 uM) + 1 uL crystallization condition (Helix screen, condition D9: 0.05 M bis-Tris (pH 7), 2 M ammonium sulfate, 5% v/v PEG 400). Reservoir contained 70 uL of crystallization condition	Resolution 3.00 Å R-free 0.284
7MG9 Concanavalin A bound to DNA glycoconjugates, Man-TTTT and Man-AAAA Deposited 2021-04-12	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM), Man-TTTT (64 uM), and Man-AAAA (64 uM) + 1 uL crystallization condition (Helix screen, condition B5: 0.1 M lithium chloride, 0.01 M manganese(II) chloride tetrahydrate, 0.05 M MES (pH 6.5), 17% w/v PEG 4000). Reservoir contained 70 uL of crystallization condition	Resolution 2.55 Å R-free 0.314
7MGA Concanavalin A bound to a DNA glycoconjugate, Man-AAATTT Deposited 2021-04-12	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and Man-AAATTT (64 uM) + 1 uL crystallization condition (Helix screen, condition A3: 0.1 M sodium chloride, 0.05 M lithium chloride, 0.01 M magnesium chloride hexahydrate, 0.05 M MES (pH 6.5), 25% v/v PEG 400). Reservoir contained 70 uL of crystallization condition	Resolution 2.00 Å R-free 0.229
7MGB Concanavalin A bound to a DNA glycoconjugate, A(Man-T)AT Deposited 2021-04-12	Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	MMA methyl alpha-D-mannopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；295 K；Sitting drop comprising 1 uL of Concanavalin A (40 uM) and A(Man-T)AT (160 uM) + 1 uL crystallization condition (Helix screen, condition H10: 0.05 M lithium sulfate, 0.03 M magnesium sulfate heptahydrate, 0.05 M bis Tris (pH 8), 15% w/v PEG 3350). Reservoir contained 70 uL of crystallization condition	Resolution 2.45 Å R-free 0.262
7MGC Concanavalin A bound to a DNA glycoconjugate, G(Man-T)AC Deposited 2021-04-12	Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	MMA methyl alpha-D-mannopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (40 uM) and G(Man-T)AC (160 uM) + 1 uL crystallization condition (Helix screen, condition H6: 0.1 M potassium chloride, 0.002 M spermine tetrahydrochloride, 0.05 M bis-Tris (pH 7), 15% w/v PEG 2000 MME). Reservoir contained 70 uL of crystallization condition	Resolution 2.92 Å R-free 0.277
7MGD Concanavalin A bound to a DNA glycoconjugate, T(Man-T)TT Deposited 2021-04-12	Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MMA methyl alpha-D-mannopyranoside × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and T(Man-T)TT (128 uM) + 1 uL crystallization condition (Helix screen, condition B6: 0.1 M sodium chloride, 0.005 M strontium chloride hexahydrate, 0.05 M MES (pH 6.5), 17% w/v PEG 4000). Reservoir contained 70 uL of crystallization condition	Resolution 2.05 Å R-free 0.255
8WMG Structure of ConA/Man3 Deposited 2023-10-03	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	WRW 4-[3,5-bis(4-carboxyphenyl)phenyl]benzoic acid × 1 ETA ETHANOLAMINE × 3 MAN alpha-D-mannopyranose × 3 MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；buffer: 20 mM HEPES, 5 mM CaCl2, 5 mM MnCl2, pH = 7.5, Precipitant: 200 mM Ammonium phosphate	Resolution 1.97 Å R-free 0.212
8WMK Structure of ConA/Man2 Deposited 2023-10-03	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	WU0 4-[3-(4-carboxyphenyl)phenyl]benzoic acid × 2 ETA ETHANOLAMINE × 4 MAN alpha-D-mannopyranose × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；buffer: 20 mM HEPES, 5 mM CaCl2, 5 mM MnCl2; pH = 7.2, precipitant: Ammonium phosphate	Resolution 2.17 Å R-free 0.267
9B34 Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two ConA dimers. Type I interface between GluK2 ligand-binding domain and ConA Deposited 2024-03-18	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain E 164–281（118 aa） Chain E 30–148（119 aa） Chain F 164–281（118 aa） Chain F 30–148（119 aa）	Not recorded	ZN ZINC ION × 2 CA CALCIUM ION × 2	ELECTRON MICROSCOPY cryo-EM buffer pH 8 cryo-EM vitrification conditions Cryogen ETHANE	Resolution 3.58 Å
9J1A Structure of ConA without ligand Deposited 2024-08-04	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa）	Not recorded	GOL GLYCEROL × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；1.8M Ammonium Sulfate, 0.1M MES pH 6.5, 0.01M Cobalt Chloride	Resolution 1.48 Å R-free 0.213
9J1B Structure of ConA/IMI-Man Deposited 2024-08-04	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 A1EAT ~{N}-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethyl]-4-[3-[4-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethylcarbamoyl]phenyl]imidazol-3-ium-1-yl]benzamide × 2	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；buffer: 20 mM HEPES, 5 mM CaCl2, 5 mM MnCl2; pH = 7.2, precipitant: Ammonium phosphate	Resolution 2.48 Å R-free 0.228
9J1C Structure of ConA/NAP-Man Deposited 2024-08-04	Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 A1EAU ~{N}2,~{N}6-bis[2-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethoxy]ethyl]naphthalene-2,6-dicarboxamide × 2	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；0.1 M MES monohydrate pH 6.5, 12 % w/v Polyethylene glycol 20,000	Resolution 2.43 Å R-free 0.282
9J1D Structure of ConA/PHE-Man Deposited 2024-08-04	Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain B 164–281（118 aa） Chain B 30–148（119 aa）	Not recorded	A1EAW ~{N}2,~{N}9-bis[2-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethoxy]ethyl]-1,10-phenanthroline-2,9-dicarboxamide × 2 CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；0.1M Tris-HCl pH 8.5, 2.0M Ammonium phosphate monobasic	Resolution 3.49 Å R-free 0.229
9J1F Dimeric Structure of ConA/M2P-Man Deposited 2024-08-04	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain A 164–281（118 aa） Chain A 30–148（119 aa） Chain D 164–281（118 aa） Chain D 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；0.2M Sodium chloride, 0.1M Phosphate-citrate pH 4.2 10% (w/v) PEG 3000	Resolution 2.17 Å R-free 0.257
9J1F Dimeric Structure of ConA/M2P-Man Deposited 2024-08-04	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics	Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric	Chain B 164–281（118 aa） Chain B 30–148（119 aa） Chain C 164–281（118 aa） Chain C 30–148（119 aa）	Not recorded	MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2 A1EAW ~{N}2,~{N}9-bis[2-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethoxy]ethyl]-1,10-phenanthroline-2,9-dicarboxamide × 2	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；298 K；0.2M Sodium chloride, 0.1M Phosphate-citrate pH 4.2 10% (w/v) PEG 3000	Resolution 2.17 Å R-free 0.257

72 other PDB entries and 89 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence

UniProt name	CONA_CANEN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–118； UniProt 164–281 Author chain A； PDBConstruct 119–237； UniProt 30–148 Author chain B； PDBConstruct 1–118； UniProt 164–281 Author chain B； PDBConstruct 119–237； UniProt 30–148 Author chain C； PDBConstruct 1–118； UniProt 164–281 Author chain C； PDBConstruct 119–237； UniProt 30–148 Author chain D； PDBConstruct 1–118； UniProt 164–281 Author chain D； PDBConstruct 119–237； UniProt 30–148

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

P(r) Distance Distribution P(r) Distribution

Download Download SAXS (.dat) P(r) (.pr.out) CIF

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	4p9w
Deposition date deposition_date	2014-04-06
Structure title title	Structure of ConA/Rh3Man
Keywords keywords	Lectin, carbohydrate, porous framework, SUGAR BINDING PROTEIN; SUGAR BINDING PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier	30.28 Å
Radius of gyration Rg (electron density) rg_electron	29.17 Å
Forward intensity I(0) i0	175812000.00
Molecular weight molecular_weight	106030.0 kDa
Excluded volume excluded_volume	132570 Å³
Envelope volume envelope_volume	156700 Å³
Hydration-shell volume shell_volume	43716 Å³
Envelope diameter envelope_diameter	94.5 Å
Shell Rg shell_rg	37.40 Å
Envelope Rg envelope_rg	29.23 Å
Shape Rg shape_rg	29.15 Å
Total Rg total_rg	29.92 Å
Total atoms total_atoms	7480
Residues n_residues	948
Spherical-harmonic order n_harmonics	20
q range q_range	— – 0.5000 Å⁻¹
Data points n_points	101
Shell type shell_type	directional
Solvent electron density solvent_density	0.3340 e/Å³
Shell contrast contrast_shell	0.0300 e/Å³
CRYSOL version crysol_version	4.1.3

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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax	90.1 Å
Rg (real space) rg_real	30.06 Å
Rg uncertainty (real space) rg_real_error	0.47 Å
I(0) (real space) i0_real	1.7580e+08
I(0) uncertainty (real space) i0_real_error	2.4260e+06
Rg (reciprocal space) rg_reciprocal	30.15 Å
I(0) (reciprocal space) i0_reciprocal	175800000.0000
Solution quality estimate total_estimate	0.9106
Solution quality rating solution_quality	EXCELLENT a EXCELLENT solution
P(r) peaks n_peaks	2
Primary peak position r_peak_primary	39.9 Å
Skewness Skewness skewness	0.018
Kurtosis Kurtosis kurtosis	-0.673
Angular range angular_range	— – 0.2600 Å⁻¹
Current regularization parameter α current_alpha	0.0000
Highest regularization parameter α highest_alpha	26280000.0000
Real-space data points n_real_points	53
GNOM version gnom_version	4.1.3
Quality Criteria quality_criteria	AN1: 0.000; Oscil: 0.962; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.984; Smooth: 0.964

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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (5)

Entity 1 Entity 1 polymer

Description description	Concanavalin-A
Molecular weight formula_weight	25622.4 kDa
Source method src_method	man
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D
Atom count atom_count	7690

ADTIVAVELDTYPNTDIGDPSYPHIGIDIKSVRSKKTAKWNMQNGKVGTAHIIYNSVDKRLSAVVSYPNADSATVSYDVDLDNVLPEWVRVGLSASTGLYKETNTILSWSFTSKLKSNSTHETNALHFMFNQFSKDQKDLILQGDATTGTDGNLELTRVSSNGSPQGSSVGRALFYAPVHIWESSAVVASFEATFTFLIKSPDSHPADGIAFFISNIDSSIPSGSTGRLLGLFPDAN

Entity 2 Entity 2 non-polymer

Description description	;2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate ;
Molecular weight formula_weight	819.9 kDa
Source method src_method	syn
Copy count entity_count	4

Entity 3 Entity 3 non-polymer

Description description	MANGANESE (II) ION
Molecular weight formula_weight	54.9 kDa
Source method src_method	syn
Copy count entity_count	4

Entity 4 Entity 4 non-polymer

Description description	CALCIUM ION
Molecular weight formula_weight	40.1 kDa
Source method src_method	syn
Copy count entity_count	4

Entity 5 Entity 5 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	200

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7. Fold Classification (SCOP + CATH) 8 domains

SCOP 2.08 (4 domains)

Domain ID domain_id	d4p9wa_
Class class	b — All beta proteins
Fold Fold fold	b.29 — Concanavalin A-like lectins/glucanases
Superfamily Superfamily superfamily	b.29.1 — Concanavalin A-like lectins/glucanases
Family Family family	b.29.1.1 — Legume lectins

Domain ID domain_id	d4p9wb_
Class class	b — All beta proteins
Fold Fold fold	b.29 — Concanavalin A-like lectins/glucanases
Superfamily Superfamily superfamily	b.29.1 — Concanavalin A-like lectins/glucanases
Family Family family	b.29.1.1 — Legume lectins

Domain ID domain_id	d4p9wc_
Class class	b — All beta proteins
Fold Fold fold	b.29 — Concanavalin A-like lectins/glucanases
Superfamily Superfamily superfamily	b.29.1 — Concanavalin A-like lectins/glucanases
Family Family family	b.29.1.1 — Legume lectins

Domain ID domain_id	d4p9wd_
Class class	b — All beta proteins
Fold Fold fold	b.29 — Concanavalin A-like lectins/glucanases
Superfamily Superfamily superfamily	b.29.1 — Concanavalin A-like lectins/glucanases
Family Family family	b.29.1.1 — Legume lectins

CATH v4.4 (4 domains)

Domain ID domain_id	4p9wA00
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	200 —

Domain ID domain_id	4p9wB00
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	200 —

Domain ID domain_id	4p9wC00
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	200 —

Domain ID domain_id	4p9wD00
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	200 —

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8. Citations (1)

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Unit-cell length a length_a	84.000 Å
Unit-cell length b length_b	116.030 Å
Unit-cell length c length_c	84.100 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	95.03 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	8

Space group space_group	P 1 21 1
Space-group number int_tables_number	4
Crystal system crystal_system	—

Resolution resolution	2.110 Å
Low-resolution limit resolution_low	39.400 Å
R factor r_factor	0.1737
R_work r_work	0.1731
R_free r_free	0.2015

fit	/app/data/saxs_computation/p9/4p9w/4p9w.fit
pddf	/app/data/pr_computation/p9/4p9w/4p9w.pr.out
profile	/app/data/saxs_computation/p9/4p9w/4p9w.dat