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9b34

Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two ConA dimers. Type I interface between GluK2 ligand-binding domain and ConA

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Concanavalin A

OrganismNot specified

UniProt P02866

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 ZINC ION × 2 CALCIUM ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1jn2 1nxd 1nxd 1nxd 1nxd 5ygm 6h2m

7 assemblies

Homodimer
1nxd 1nxd 3enr 3nwk 3nwk 5z5l 5z5l 5z5p 5z5y 8wmg 9b34 9j1f

13 assemblies; showing the first 12

Homotetramer
1apn 1ces 1cjp 1cn1 1con 1dq6 1enq 1enr 1ens 1gic 1gkb 1jbc

52 assemblies; showing the first 12

Other homooligomers
6ahg

1 assemblies

Heteromeric or nucleic-acid complex
1bxh 1cvn 1i3h 1jw6 1jw6 1ona 1tei 1tei 1tei 3d4k 5wey 7mg5

17 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name CONA_CANEN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain E； PDBConstruct 1–118； UniProt 164–281 Author chain E； PDBConstruct 119–237； UniProt 30–148 Author chain F； PDBConstruct 1–118； UniProt 164–281 Author chain F； PDBConstruct 119–237； UniProt 30–148

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9b34
Deposition date deposition_date2024-03-18
Structure title titleStructure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two ConA dimers. Type I interface between GluK2 ligand-binding domain and ConA
Keywords keywordskainate receptor, GluK2, glutamate, positive allosteric modulator, BPAM344, open, concanavalin A, ConA, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9b34__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9b34__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9b34__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）25.90 Å
Rg (electron density)24.71 Å
Total Rg25.65 Å
Atom count3619
Residues474
Excluded volume64021 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9b34__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)