Concanavalin-A
OrganismNot specified
State in the Current Structure
| Assembly | Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Associated Components | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|
| 1 | Other combination Monomer Protein × 1 其他Polymer 1 PDB declaration: monomeric（1） Consistent with protein copy count | Chain A； UniProt 164–281 Chain A； UniProt 30–148 | Fragment：unp residues 164-281; unp residues 30-148 | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose × 1 MN MANGANESE (II) ION × 1 CA CALCIUM ION × 1 | Experimental method not declared X-ray crystallization conditions：VAPOR DIFFUSION, SITTING DROP；pH 5；291 K；10% PEG 6K, 0.1 M sodium citrate, pH 5 in H2O | Resolution not provided |
Other States of the Same Protein in the Database
Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.
| Other PDB | Difference from Current Entry 5WEY | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1APN THE CRYSTALLOGRAPHIC STRUCTURE OF METAL-FREE CONCANAVALIN A AT 2.5 ANGSTROMS RESOLUTION Deposited 1995-07-28 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–290（127 aa）
Chain B
164–290（127 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.50 Å R-free 0.247 |
| 1BXH CONCANAVALIN A COMPLEXED TO METHYL ALPHA1-2 MANNOBIOSIDE Deposited 1998-10-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Fragment：UNP P02866 residues 164-281, 30-148
Chain A
30–148（119 aa）
Fragment：UNP P02866 residues 164-281, 30-148
Chain B
164–281（118 aa）
Fragment：UNP P02866 residues 164-281, 30-148
Chain B
30–148（119 aa）
Fragment：UNP P02866 residues 164-281, 30-148
Chain C
164–281（118 aa）
Fragment：UNP P02866 residues 164-281, 30-148
Chain C
30–148（119 aa）
Fragment：UNP P02866 residues 164-281, 30-148
Chain D
164–281（118 aa）
Fragment：UNP P02866 residues 164-281, 30-148
Chain D
30–148（119 aa）
Fragment：UNP P02866 residues 164-281, 30-148
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MMA methyl alpha-D-mannopyranoside × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 7；13.5% PEG 6K, 1.0M LICL, 0.1M TRIS PH 7.0
|
Resolution 2.75 Å R-free 0.238 |
| 1CES CRYSTALS OF DEMETALLIZED CONCANAVALIN A SOAKED WITH ZINC HAVE A ZINC ION BOUND IN THE S1 SITE Deposited 1996-02-15 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
|
Not recorded | ZN ZINC ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 5；pH 5.
|
Resolution 2.70 Å R-free 0.249 |
| 1CJP CONCANAVALIN A COMPLEX WITH 4'-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE Deposited 1996-10-03 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
Chain C
30–148（119 aa）
Chain D
30–148（119 aa）
|
Not recorded | MUG 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOSE × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.78 Å R-free 0.216 |
| 1CN1 CRYSTAL STRUCTURE OF DEMETALLIZED CONCANAVALIN A. THE METAL-BINDING REGION Deposited 1981-12-21 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
1–237（237 aa）
Chain B
1–237（237 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 3.20 Å |
| 1CON THE REFINED STRUCTURE OF CADMIUM SUBSTITUTED CONCANAVALIN A AT 2.0 ANGSTROMS RESOLUTION Deposited 1993-03-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
|
Not recorded | CD CADMIUM ION × 8 CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.00 Å |
| 1CVN CONCANAVALIN A COMPLEXED TO TRIMANNOSIDE Deposited 1995-08-09 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
Chain C
30–148（119 aa）
Chain D
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 9；pH 9.0
|
Resolution 2.30 Å R-free 0.255 |
| 1DQ6 Manganese;Manganese concanavalin A at pH 7.0 Deposited 1999-12-30 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；277 K；2 M ammonium sulphate, 60 mM sodium acetate at pH 7, 3% PEGMe 5000, 1 mM MnCl2, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 277.0K
|
Resolution 1.90 Å |
| 1ENQ CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH ZINC HAVING A ZINC ION BOUND IN THE S1 SITE Deposited 1996-03-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
Chain C
30–148（119 aa）
Chain D
30–148（119 aa）
|
Not recorded | ZN ZINC ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 5；pH 5.
|
Resolution 2.50 Å R-free 0.284 |
| 1ENR CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH ZINC AND CALCIUM HAVING A ZINC ION BOUND IN THE S1 SITE AND A CALCIUM ION BOUND IN THE S2 SITE Deposited 1996-03-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
|
Not recorded | CA CALCIUM ION × 4 ZN ZINC ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 7；pH 7.
|
Resolution 1.83 Å |
| 1ENS CRYSTALS OF DEMETALLIZED CONCANAVALIN A SOAKED WITH COBALT HAVING A COBALT ION BOUND IN THE S1 SITE Deposited 1996-03-20 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
|
Not recorded | CO COBALT (II) ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 5；pH 5.
|
Resolution 2.80 Å R-free 0.259 |
| 1GIC CONCANAVALIN A COMPLEXED WITH METHYL ALPHA-D-GLUCOPYRANOSIDE Deposited 1996-08-08 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
|
Not recorded | GYP methyl alpha-D-glucopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
dialysis；pH 6.8；DIALYSIS; 5MM PROTEIN CONCENTRATION WITH, pH 6.8, dialysis
|
Resolution 2.00 Å |
| 1GKB CONCANAVALIN A, NEW CRYSTAL FORM Deposited 2001-08-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MG MAGNESIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；HANGING DROP, 30MG/ML, 10+10 UL 1 ML WELL, TRIS/HCL PH 8.0, 25%
|
Resolution 1.56 Å R-free 0.206 |
| 1I3H CONCANAVALIN A-DIMANNOSE STRUCTURE Deposited 2001-02-15 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Fragment：residues 164-281,residues 30-148
Chain A
30–148（119 aa）
Fragment：residues 164-281,residues 30-148
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5；298 K；PEG 6000, citirc acid, manganese chloride, calcium chloride, pH 5.0, VAPOR DIFFUSION, SITTING DROP, temperature 298K
|
Resolution 1.20 Å R-free 0.190 |
| 1JBC CONCANAVALIN A Deposited 1996-08-23 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
8–148（141 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.15 Å R-free 0.167 |
| 1JN2 Crystal Structure of meso-tetrasulphonatophenyl porphyrin complexed with Concanavalin A Deposited 2001-07-22 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain P
164–281（118 aa）
Fragment：UNP P02866 residues 164-281, 30-148
Chain P
30–148（119 aa）
Fragment：UNP P02866 residues 164-281, 30-148
|
Not recorded | CA CALCIUM ION × 1 MN MANGANESE (II) ION × 1 SFP 5,10,15,20-TETRAKIS(4-SULPFONATOPHENYL)-21H,23H-PORPHINE × 1 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.90 Å R-free 0.232 |
| 1JN2 Crystal Structure of meso-tetrasulphonatophenyl porphyrin complexed with Concanavalin A Deposited 2001-07-22 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain P
164–281（118 aa）
Fragment：UNP P02866 residues 164-281, 30-148
Chain P
30–148（119 aa）
Fragment：UNP P02866 residues 164-281, 30-148
|
Not recorded | CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 SFP 5,10,15,20-TETRAKIS(4-SULPFONATOPHENYL)-21H,23H-PORPHINE × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.90 Å R-free 0.232 |
| 1JW6 Crystal Structure of the Complex of Concanavalin A and Hexapeptide Deposited 2001-09-02 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 PTD PENTANEDIAL × 4 IPA ISOPROPYL ALCOHOL × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.45；300 K；Sodium phosphate , pH 5.45, VAPOR DIFFUSION, HANGING DROP, temperature 300.0K
|
Resolution 1.93 Å R-free 0.250 |
| 1JW6 Crystal Structure of the Complex of Concanavalin A and Hexapeptide Deposited 2001-09-02 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 PTD PENTANEDIAL × 4 IPA ISOPROPYL ALCOHOL × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.45；300 K；Sodium phosphate , pH 5.45, VAPOR DIFFUSION, HANGING DROP, temperature 300.0K
|
Resolution 1.93 Å R-free 0.250 |
| 1NLS CONCANAVALIN A AND ITS BOUND SOLVENT AT 0.94A RESOLUTION Deposited 1997-01-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.8；pH 6.8
|
Resolution 0.94 Å R-free 0.154 |
| 1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain 1
164–281（118 aa）
Chain 1
30–148（119 aa）
|
Not recorded | AZI AZIDE ION × 3 MN MANGANESE (II) ION × 2 NA SODIUM ION × 1 GOL GLYCEROL × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K
|
Resolution 1.90 Å R-free 0.201 |
| 1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain 2
164–281（118 aa）
Chain 2
30–148（119 aa）
|
Not recorded | AZI AZIDE ION × 5 MN MANGANESE (II) ION × 2 NA SODIUM ION × 1 GOL GLYCEROL × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K
|
Resolution 1.90 Å R-free 0.201 |
| 1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain 3
164–281（118 aa）
Chain 3
30–148（119 aa）
|
Not recorded | AZI AZIDE ION × 4 MN MANGANESE (II) ION × 2 NA SODIUM ION × 1 GOL GLYCEROL × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K
|
Resolution 1.90 Å R-free 0.201 |
| 1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain 4
164–281（118 aa）
Chain 4
30–148（119 aa）
|
Not recorded | AZI AZIDE ION × 4 MN MANGANESE (II) ION × 2 NA SODIUM ION × 1 GOL GLYCEROL × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K
|
Resolution 1.90 Å R-free 0.201 |
| 1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 5 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain 1
164–281（118 aa）
Chain 1
30–148（119 aa）
Chain 2
164–281（118 aa）
Chain 2
30–148（119 aa）
|
Not recorded | AZI AZIDE ION × 16 MN MANGANESE (II) ION × 8 NA SODIUM ION × 4 GOL GLYCEROL × 28 |
X-RAY DIFFRACTION
X-ray crystallization conditions
Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K
|
Resolution 1.90 Å R-free 0.201 |
| 1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 6 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain 3
164–281（118 aa）
Chain 3
30–148（119 aa）
Chain 4
164–281（118 aa）
Chain 4
30–148（119 aa）
|
Not recorded | AZI AZIDE ION × 16 MN MANGANESE (II) ION × 8 NA SODIUM ION × 4 GOL GLYCEROL × 22 |
X-RAY DIFFRACTION
X-ray crystallization conditions
Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K
|
Resolution 1.90 Å R-free 0.201 |
| 1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 7 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain 1
164–281（118 aa）
Chain 1
30–148（119 aa）
Chain 2
164–281（118 aa）
Chain 2
30–148（119 aa）
|
Not recorded | AZI AZIDE ION × 8 MN MANGANESE (II) ION × 4 NA SODIUM ION × 2 GOL GLYCEROL × 14 |
X-RAY DIFFRACTION
X-ray crystallization conditions
Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K
|
Resolution 1.90 Å R-free 0.201 |
| 1NXD Crystal structure of MnMn Concanavalin A Deposited 2003-02-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 8 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain 3
164–281（118 aa）
Chain 3
30–148（119 aa）
Chain 4
164–281（118 aa）
Chain 4
30–148（119 aa）
|
Not recorded | AZI AZIDE ION × 8 MN MANGANESE (II) ION × 4 NA SODIUM ION × 2 GOL GLYCEROL × 11 |
X-RAY DIFFRACTION
X-ray crystallization conditions
Gel Acupuncture Method (GAME)；pH 8；293 K；PEG 6000, Sodium Chloride, Calcium Chloride, Manganese Chloride, Sodium Azide, Tris-HCl , pH 8, Gel Acupuncture Method (GAME), temperature 293K
|
Resolution 1.90 Å R-free 0.201 |
| 1ONA CO-CRYSTALS OF CONCANAVALIN A WITH METHYL-3,6-DI-O-(ALPHA-D-MANNOPYRANOSYL)-ALPHA-D-MANNOPYRANOSIDE Deposited 1996-07-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
Chain C
30–148（119 aa）
Chain D
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.5；13% POLYETHYLENEGLYCOLMETHYLETHER, 40 MM HEPES PH 6.5
|
Resolution 2.35 Å R-free 0.282 |
| 1QNY X-ray refinement of D2O soaked crystal of concanavalin A Deposited 1999-10-26 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain A
164–281（118 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.5；CRYSTALS SELECTED FOR X-RAY STUDY WERE TRANSFERRED TO A 1ML BUFFER MADE OF 99.9% D2O WITH 0.1M NANO3, 0.05M TRIS-ACETATE, 1MM MNCL2 AND 1MM CACL2 PH 6.5.
|
Resolution 1.80 Å R-free 0.198 |
| 1SCR HIGH-RESOLUTION STRUCTURES OF SINGLE-METAL-SUBSTITUTED CONCANAVALIN A: THE CO,CA-PROTEIN AT 1.6 ANGSTROMS AND THE NI,CA-PROTEIN AT 2.0 ANGSTROMS Deposited 1993-12-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
|
Not recorded | NI NICKEL (II) ION × 4 CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.00 Å |
| 1SCS HIGH-RESOLUTION STRUCTURES OF SINGLE-METAL-SUBSTITUTED CONCANAVALIN A: THE CO,CA-PROTEIN AT 1.6 ANGSTROMS AND THE NI,CA-PROTEIN AT 2.0 ANGSTROMS Deposited 1993-12-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
|
Not recorded | CO COBALT (II) ION × 4 CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.60 Å |
| 1TEI STRUCTURE OF CONCANAVALIN A COMPLEXED TO BETA-D-GLCNAC (1,2)ALPHA-D-MAN-(1,6)[BETA-D-GLCNAC(1,2)ALPHA-D-MAN (1,6)]ALPHA-D-MAN Deposited 1997-05-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
Chain C
30–148（119 aa）
Chain D
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 5.5；POLYETHYLENE GLYCOL 15%, pH 5.5
|
Resolution 2.70 Å R-free 0.219 |
| 1TEI STRUCTURE OF CONCANAVALIN A COMPLEXED TO BETA-D-GLCNAC (1,2)ALPHA-D-MAN-(1,6)[BETA-D-GLCNAC(1,2)ALPHA-D-MAN (1,6)]ALPHA-D-MAN Deposited 1997-05-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain E
30–148（119 aa）
Chain F
30–148（119 aa）
Chain G
30–148（119 aa）
Chain H
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 5.5；POLYETHYLENE GLYCOL 15%, pH 5.5
|
Resolution 2.70 Å R-free 0.219 |
| 1TEI STRUCTURE OF CONCANAVALIN A COMPLEXED TO BETA-D-GLCNAC (1,2)ALPHA-D-MAN-(1,6)[BETA-D-GLCNAC(1,2)ALPHA-D-MAN (1,6)]ALPHA-D-MAN Deposited 1997-05-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Other combination Homooligomer；Protein × 8 PDB declaration: octameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
Chain C
30–148（119 aa）
Chain D
30–148（119 aa）
Chain E
30–148（119 aa）
Chain F
30–148（119 aa）
Chain G
30–148（119 aa）
Chain H
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 8 CA CALCIUM ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 5.5；POLYETHYLENE GLYCOL 15%, pH 5.5
|
Resolution 2.70 Å R-free 0.219 |
| 1VAL CONCANAVALIN A COMPLEX WITH 4'-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE Deposited 1996-01-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
Chain C
30–148（119 aa）
Chain D
30–148（119 aa）
|
Not recorded | PNG 4-nitrophenyl alpha-D-glucopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 3.00 Å R-free 0.274 |
| 1VAM CONCANAVALIN A COMPLEX WITH 4'-NITROPHENYL-ALPHA-D-MANNOPYRANOSIDE Deposited 1996-01-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
Chain C
30–148（119 aa）
Chain D
30–148（119 aa）
|
Not recorded | PNA 4-nitrophenyl alpha-D-mannopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.75 Å R-free 0.260 |
| 1XQN The 15k neutron structure of saccharide-free concanavalin A Deposited 2004-10-13 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
NEUTRON DIFFRACTION
X-ray crystallization conditions
BATCH DIALYSIS；pH 6.5；293 K；0.1M NaNO3, 0.05M Tris-acetate, 1mM MnCl2, 1mM CaCl2 (all in D2O), pH 6.50, BATCH DIALYSIS, temperature 293.0K
|
Resolution 2.50 Å R-free 0.320 |
| 2CNA THE COVALENT AND THREE-DIMENSIONAL STRUCTURE OF CONCANAVALIN A, IV.ATOMIC COORDINATES,HYDROGEN BONDING,AND QUATERNARY STRUCTURE Deposited 1975-04-01 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–290（127 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.00 Å |
| 2CTV HIGH RESOLUTION CRYSTALLOGRAPHIC STUDIES OF NATIVE CONCANAVALIN A USING RAPID LAUE DATA COLLECTION METHODS AND THE INTRODUCTION OF A MONOCHROMATIC LARGE-ANGLE OSCILLATION TECHNIQUE (LOT) Deposited 1993-08-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.95 Å |
| 2ENR CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH CADMIUM HAVING A CADMIUM ION BOUND IN BOTH THE S1 SITE AND THE S2 SITE Deposited 1998-07-14 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
8–148（141 aa）
|
Not recorded | CD CADMIUM ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 5；pH 5.0
|
Resolution 2.35 Å |
| 2UU8 X-ray structure of Ni, Ca concanavalin A at Ultra-high resolution (0. 94A) Deposited 2007-03-01 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | NI NICKEL (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.5；pH 6.5
|
Resolution 0.94 Å R-free 0.142 |
| 2YZ4 The neutron structure of concanavalin A at 2.2 Angstroms Deposited 2007-05-02 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
NEUTRON DIFFRACTION
X-ray crystallization conditions
BATCH DIALYSIS；pH 6.5；293 K；0.1M NaNO3, 0.05M Tris-acetate, 1mM MnCl2, 1mM CaCl2, pH 6.5, BATCH DIALYSIS, temperature 293K
|
Resolution 2.20 Å R-free 0.312 |
| 3CNA STRUCTURE OF CONCANAVALIN A AT 2.4 ANGSTROMS RESOLUTION Deposited 1976-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
1–237（237 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.40 Å |
| 3D4K Concanavalin A Complexed to a Synthetic Analog of the Trimannoside Deposited 2008-05-14 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 GOL GLYCEROL × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.8；291 K；10-16% PEG 6000, 100 mM Sodium cacodylate, 50 mM NaCL, 1 mM MnCL2, 1 mM CaCL2, pH 6.8, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 1.80 Å R-free 0.238 |
| 3ENR ZINC-CALCIUM CONCANAVALIN A AT PH 6.15 Deposited 1999-02-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | ZN ZINC ION × 4 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.15；ZNCL2, CACL2, (NH4)2SO4, sodium acetate, pH 6.15, VAPOR DIFFUSION, SITTING DROP
|
Resolution 2.40 Å R-free 0.283 |
| 3NWK A second C2221 form of concanavalin A (Canavalia ensiformis) Deposited 2010-07-09 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
|
Not recorded | CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 GOL GLYCEROL × 10 |
X-RAY DIFFRACTION
X-ray crystallization conditions
hanging drop vapor diffusion using polymer-induced heteronucleation；pH 8.5；273 K；10 mM Tris, pH 8.5, 1 M ammonium sulfate, hanging drop vapor diffusion using polymer-induced heteronucleation, temperature 273K
|
Resolution 2.09 Å R-free 0.212 |
| 3NWK A second C2221 form of concanavalin A (Canavalia ensiformis) Deposited 2010-07-09 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 GOL GLYCEROL × 12 |
X-RAY DIFFRACTION
X-ray crystallization conditions
hanging drop vapor diffusion using polymer-induced heteronucleation；pH 8.5；273 K；10 mM Tris, pH 8.5, 1 M ammonium sulfate, hanging drop vapor diffusion using polymer-induced heteronucleation, temperature 273K
|
Resolution 2.09 Å R-free 0.212 |
| 3NWK A second C2221 form of concanavalin A (Canavalia ensiformis) Deposited 2010-07-09 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
|
Not recorded | CA CALCIUM ION × 2 MN MANGANESE (II) ION × 2 GOL GLYCEROL × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
hanging drop vapor diffusion using polymer-induced heteronucleation；pH 8.5；273 K；10 mM Tris, pH 8.5, 1 M ammonium sulfate, hanging drop vapor diffusion using polymer-induced heteronucleation, temperature 273K
|
Resolution 2.09 Å R-free 0.212 |
| 3NWK A second C2221 form of concanavalin A (Canavalia ensiformis) Deposited 2010-07-09 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | CA CALCIUM ION × 2 MN MANGANESE (II) ION × 2 GOL GLYCEROL × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
hanging drop vapor diffusion using polymer-induced heteronucleation；pH 8.5；273 K；10 mM Tris, pH 8.5, 1 M ammonium sulfate, hanging drop vapor diffusion using polymer-induced heteronucleation, temperature 273K
|
Resolution 2.09 Å R-free 0.212 |
| 4P9W Structure of ConA/Rh3Man Deposited 2014-04-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Fragment：UNP residues 164-281, 30-148
Chain A
30–148（119 aa）
Fragment：UNP residues 164-281, 30-148
Chain B
164–281（118 aa）
Fragment：UNP residues 164-281, 30-148
Chain B
30–148（119 aa）
Fragment：UNP residues 164-281, 30-148
Chain C
164–281（118 aa）
Fragment：UNP residues 164-281, 30-148
Chain C
30–148（119 aa）
Fragment：UNP residues 164-281, 30-148
Chain D
164–281（118 aa）
Fragment：UNP residues 164-281, 30-148
Chain D
30–148（119 aa）
Fragment：UNP residues 164-281, 30-148
|
Not recorded | R3M 2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIQUID DIFFUSION；pH 7.2；298 K；buffer: 20 mM HEPES, 5 mM of CaCl2, and 5 mM of MnCl2; pH = 7.2. The crystal was obtained by diffusion method in glass tube sequentially put with ConA solution, pure buffer, and the ligand solution.
|
Resolution 2.11 Å R-free 0.202 |
| 4P9X Structure of ConA/Rh3Glu complex Deposited 2014-04-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Fragment：UNP residues 164-281, 30-148
Chain A
30–148（119 aa）
Fragment：UNP residues 164-281, 30-148
Chain B
164–281（118 aa）
Fragment：UNP residues 164-281, 30-148
Chain B
30–148（119 aa）
Fragment：UNP residues 164-281, 30-148
Chain C
164–281（118 aa）
Fragment：UNP residues 164-281, 30-148
Chain C
30–148（119 aa）
Fragment：UNP residues 164-281, 30-148
Chain D
164–281（118 aa）
Fragment：UNP residues 164-281, 30-148
Chain D
30–148（119 aa）
Fragment：UNP residues 164-281, 30-148
|
Not recorded | R3G 2-[2-(2-{4-[(alpha-D-glucopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIQUID DIFFUSION；pH 7.2；298 K；buffer: 20 mM HEPES, 5 mM of CaCl2, and 5 mM of MnCl2; pH = 7.2. The crystal was obtained by diffusion method in glass tube sequentially put with ConA solution, pure buffer, and the ligand solution.
|
Resolution 2.06 Å R-free 0.295 |
| 4P9Y Structure of ConA/Rh4man Deposited 2014-04-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Fragment：UNP residues 164-281, 30-148
Chain A
30–148（119 aa）
Fragment：UNP residues 164-281, 30-148
Chain B
164–281（118 aa）
Fragment：UNP residues 164-281, 30-148
Chain B
30–148（119 aa）
Fragment：UNP residues 164-281, 30-148
|
Not recorded | 2KO 2-{2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethoxy}ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIQUID DIFFUSION；pH 7.2；298 K；buffer: 20 mM HEPES, 5 mM of CaCl2, and 5 mM of MnCl2; pH = 7.2. The crystal was obtained by diffusion method in glass tube sequentially put with ConA solution, pure buffer, and the ligand solution.
|
Resolution 1.89 Å R-free 0.258 |
| 4PF5 Crystal structure of Concanavalin A complexed with a synthetic derivative of high-mannose chain Deposited 2014-04-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: Tetrameric |
Chain A
164–281（118 aa）
Fragment：Residues 164-281, 30-148
Chain A
30–148（119 aa）
Fragment：Residues 164-281, 30-148
Chain B
164–281（118 aa）
Fragment：Residues 164-281, 30-148
Chain B
30–148（119 aa）
Fragment：Residues 164-281, 30-148
|
Not recorded | MN MANGANESE (II) ION × 8 M3N 4-(hydroxymethyl)-1-(alpha-D-mannopyranosyl)-1H-1,2,3-triazole × 4 EDO 1,2-ETHANEDIOL × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；Sodium Acetate, 1,4-dioxane
|
Resolution 2.04 Å R-free 0.227 |
| 5CNA REFINED STRUCTURE OF CONCANAVALIN A COMPLEXED WITH ALPHA-METHYL-D-MANNOPYRANOSIDE AT 2.0 ANGSTROMS RESOLUTION AND COMPARISON WITH THE SACCHARIDE-FREE STRUCTURE Deposited 1994-02-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–148（119 aa）
Chain B
30–148（119 aa）
Chain C
30–148（119 aa）
Chain D
30–148（119 aa）
|
Not recorded | MMA methyl alpha-D-mannopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.00 Å |
| 5O6N High pressure flash cooled concanavalin A Deposited 2017-06-07 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 NA SODIUM ION × 4 CL CHLORIDE ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；291 K；10 mg/ml Concanavalin A in 0.025 M HEPES pH 7.0 were mixed in a 1:1 ratio with 6 % (w/v) PEG 8000 and 0.1 M Tris pH 8.5.
|
Resolution 1.35 Å R-free 0.164 |
| 5YGM Monomeric structure of concanavalin A at pH 7.5 from Carnivalia ensiformis Deposited 2017-09-24 | Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | CA CALCIUM ION × 1 MN MANGANESE (II) ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；PEK6K, MPD in HEPES, pH 7.5
|
Resolution 1.60 Å R-free 0.196 |
| 5Z5L Crystal structure of ConA-R5M Deposited 2018-01-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2 96O (1-methyl-1H-1,2,3-triazol-4-yl)methyl alpha-D-mannopyranoside × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.2；293 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2
|
Resolution 2.30 Å R-free 0.277 |
| 5Z5L Crystal structure of ConA-R5M Deposited 2018-01-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.2；293 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2
|
Resolution 2.30 Å R-free 0.277 |
| 5Z5N Crystal structure of ConA-R1M Deposited 2018-01-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 MAN alpha-D-mannopyranose × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.2；300 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2 pH 7.2
|
Resolution 2.04 Å R-free 0.225 |
| 5Z5P Crystal structure of ConA-R3M Deposited 2018-01-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 2 CA CALCIUM ION × 3 R3M 2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.2；300 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2 pH 7.2
|
Resolution 1.40 Å R-free 0.241 |
| 5Z5Y Crystal structure of ConA-R4M Deposited 2018-01-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | 2KO 2-{2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethoxy}ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 2 MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2 CL CHLORIDE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.2；300 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2 pH 7.2
|
Resolution 1.89 Å R-free 0.244 |
| 5Z5Y Crystal structure of ConA-R4M Deposited 2018-01-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | 2KO 2-{2-[2-(2-{4-[(alpha-D-mannopyranosyloxy)methyl]-1H-1,2,3-triazol-1-yl}ethoxy)ethoxy]ethoxy}ethyl 2-[3,6-bis(diethylamino)-9H-xanthen-9-yl]benzoate × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 CL CHLORIDE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.2；300 K；20% polyethylene glycol 6000, 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2 pH 7.2
|
Resolution 1.89 Å R-free 0.244 |
| 5ZAC Crystal structure of ConA-R2M Deposited 2018-02-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 6 MAN alpha-D-mannopyranose × 2 TA5 2H-1,2,3-TRIAZOL-4-YLMETHANOL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.2；300 K；each 0.2 mM ConA in 20 mM HEPES, 100 mM NaCl, 5 mM CaCl2, 5 mM MnCl2 pH 7.2
|
Resolution 2.59 Å R-free 0.372 |
| 6AHG Trimeric structure of concanavalin A from Canavalia ensiformis Deposited 2018-08-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
|
Not recorded | CA CALCIUM ION × 3 CD CADMIUM ION × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；Polyethylene glycol 400, 0.1 M Cadmium chloride hydrate, 0.1 M Sodium acetate trihydrate pH 4.6
|
Resolution 2.83 Å R-free 0.279 |
| 6H2M Long wavelength Mesh&Collect native SAD phasing on microcrystals Deposited 2018-07-13 | Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 1 CA CALCIUM ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；drops made from equal amounts of protein solution (1 l, 10 mg/ml in water) and reservoir solution (1l, 34%(v/v) PEG 1500), buffered with 5mM HEPES, pH 6.0
|
Resolution 1.93 Å R-free 0.177 |
| 6XT6 pro-concanavalin A: Precursor of circularly permuted concanavalin A Deposited 2020-07-17 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
30–290（261 aa）
Chain B
30–290（261 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 8 ZN ZINC ION × 4 EDO 1,2-ETHANEDIOL × 30 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；289 K；Zinc chloride, HEPES, PEG 6000
|
Resolution 2.10 Å R-free 0.244 |
| 7MG1 Concanavalin A crystallized without DNA glycoconjugate Deposited 2021-04-12 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) + 1 uL crystallization condition (Helix screen, condition H3: 0.1 M potassium chloride, 0.005 M barium chloride dihydrate, 0.05 M bis-Tris (pH 7), 12% w/v PEG 8000). Reservoir contained 70 uL of crystallization condition.
|
Resolution 2.00 Å R-free 0.262 |
| 7MG2 Concanavalin A crystallized in the presence of Man-8 Deposited 2021-04-12 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and mannose-squaramide (128 uM) + 1 uL crystallization condition (Helix screen, condition B6: 0.1 M sodium chloride, 0.005 M strontium chloride hexahydrate, 0.05 M MES (pH 6.5), 17% w/v PEG 4000). Reservoir contained 70 uL of crystallization condition.
|
Resolution 1.80 Å R-free 0.230 |
| 7MG3 Concanavalin A crystallized in the presence of H2N-ATAT Deposited 2021-04-12 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and 5'-ATAT-3' (128 uM) + 1 uL crystallization condition (Helix screen, condition D11: 0.2 M lithium chloride, 0.05 M bis-Tris (pH 7), 22% w/v PEG 2000 MME). Reservoir contained 70 uL of crystallization condition.
|
Resolution 1.60 Å R-free 0.213 |
| 7MG4 Concanavalin A crystallized in the presence of Gal-ATAT Deposited 2021-04-12 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and Gal-ATAT (128 uM) + 1 uL crystallization condition (Helix screen, condition H9: 0.1 M potassium chloride, 0.002 M spermine tetrahydrochloride, 0.05 M bis-Tris (pH 7.5), 7% w/v PEG 8000). Reservoir contained 70 uL of crystallization condition.
|
Resolution 2.00 Å R-free 0.237 |
| 7MG5 Concanavalin A bound to a DNA glycoconjugate, Man-ATAT Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (40 uM) and Man-ATAT (160 uM) + 1 uL crystallization condition (Helix screen, condition D9: 0.05 M bis-Tris (pH 7), 2 M ammonium sulfate, 5% v/v PEG 400). Reservoir contained 70 uL of crystallization condition.
|
Resolution 2.10 Å R-free 0.245 |
| 7MG6 Concanavalin A bound to a DNA glycoconjugate, Man-AGCT Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (40 uM) and Man-AGCT (160 uM) + 1 uL crystallization condition (Helix screen, condition D3: 0.2 M lithium sulfate, 0.05 M bis Tris (pH 7), 20% v/v MPD). Reservoir contained 70 uL of crystallization condition.
|
Resolution 1.70 Å R-free 0.207 |
| 7MG7 Concanavalin A bound to a DNA glycoconjugate, Man-GTAC Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and Man-GTAC (128 uM) + 1 uL crystallization condition (Helix screen, condition A4: 0.2 M potassium chloride, 0.005 M hexammine cobalt(III) chloride, 0.05 M MES (pH 6.5), 25% v/v PEG 400). Reservoir contained 70 uL of crystallization condition
|
Resolution 1.75 Å R-free 0.215 |
| 7MG8 Concanavalin A bound to a DNA glycoconjugate, Man-CGCG Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；295 K；Sitting drop comprising 1 uL of Concanavalin A (80 uM) and Man-CGCG (160 uM) + 1 uL crystallization condition (Helix screen, condition D9: 0.05 M bis-Tris (pH 7), 2 M ammonium sulfate, 5% v/v PEG 400). Reservoir contained 70 uL of crystallization condition
|
Resolution 3.00 Å R-free 0.284 |
| 7MG9 Concanavalin A bound to DNA glycoconjugates, Man-TTTT and Man-AAAA Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM), Man-TTTT (64 uM), and Man-AAAA (64 uM) + 1 uL crystallization condition (Helix screen, condition B5: 0.1 M lithium chloride, 0.01 M manganese(II) chloride tetrahydrate, 0.05 M MES (pH 6.5), 17% w/v PEG 4000). Reservoir contained 70 uL of crystallization condition
|
Resolution 2.55 Å R-free 0.314 |
| 7MGA Concanavalin A bound to a DNA glycoconjugate, Man-AAATTT Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MAN alpha-D-mannopyranose × 4 SQ0 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and Man-AAATTT (64 uM) + 1 uL crystallization condition (Helix screen, condition A3: 0.1 M sodium chloride, 0.05 M lithium chloride, 0.01 M magnesium chloride hexahydrate, 0.05 M MES (pH 6.5), 25% v/v PEG 400). Reservoir contained 70 uL of crystallization condition
|
Resolution 2.00 Å R-free 0.229 |
| 7MGB Concanavalin A bound to a DNA glycoconjugate, A(Man-T)AT Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | MMA methyl alpha-D-mannopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；295 K；Sitting drop comprising 1 uL of Concanavalin A (40 uM) and A(Man-T)AT (160 uM) + 1 uL crystallization condition (Helix screen, condition H10: 0.05 M lithium sulfate, 0.03 M magnesium sulfate heptahydrate, 0.05 M bis Tris (pH 8), 15% w/v PEG 3350). Reservoir contained 70 uL of crystallization condition
|
Resolution 2.45 Å R-free 0.262 |
| 7MGC Concanavalin A bound to a DNA glycoconjugate, G(Man-T)AC Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | MMA methyl alpha-D-mannopyranoside × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (40 uM) and G(Man-T)AC (160 uM) + 1 uL crystallization condition (Helix screen, condition H6: 0.1 M potassium chloride, 0.002 M spermine tetrahydrochloride, 0.05 M bis-Tris (pH 7), 15% w/v PEG 2000 MME). Reservoir contained 70 uL of crystallization condition
|
Resolution 2.92 Å R-free 0.277 |
| 7MGD Concanavalin A bound to a DNA glycoconjugate, T(Man-T)TT Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 MMA methyl alpha-D-mannopyranoside × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；Sitting drop comprising 1 uL of Concanavalin A (32 uM) and T(Man-T)TT (128 uM) + 1 uL crystallization condition (Helix screen, condition B6: 0.1 M sodium chloride, 0.005 M strontium chloride hexahydrate, 0.05 M MES (pH 6.5), 17% w/v PEG 4000). Reservoir contained 70 uL of crystallization condition
|
Resolution 2.05 Å R-free 0.255 |
| 8WMG Structure of ConA/Man3 Deposited 2023-10-03 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | WRW 4-[3,5-bis(4-carboxyphenyl)phenyl]benzoic acid × 1 ETA ETHANOLAMINE × 3 MAN alpha-D-mannopyranose × 3 MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；buffer: 20 mM HEPES, 5 mM CaCl2, 5 mM MnCl2, pH = 7.5, Precipitant: 200 mM Ammonium phosphate
|
Resolution 1.97 Å R-free 0.212 |
| 8WMK Structure of ConA/Man2 Deposited 2023-10-03 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | WU0 4-[3-(4-carboxyphenyl)phenyl]benzoic acid × 2 ETA ETHANOLAMINE × 4 MAN alpha-D-mannopyranose × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；buffer: 20 mM HEPES, 5 mM CaCl2, 5 mM MnCl2; pH = 7.2, precipitant: Ammonium phosphate
|
Resolution 2.17 Å R-free 0.267 |
| 9B34 Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two ConA dimers. Type I interface between GluK2 ligand-binding domain and ConA Deposited 2024-03-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain E
164–281（118 aa）
Chain E
30–148（119 aa）
Chain F
164–281（118 aa）
Chain F
30–148（119 aa）
|
Not recorded | ZN ZINC ION × 2 CA CALCIUM ION × 2 |
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.58 Å |
| 9J1A Structure of ConA without ligand Deposited 2024-08-04 | Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
|
Not recorded | GOL GLYCEROL × 4 MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；1.8M Ammonium Sulfate, 0.1M MES pH 6.5, 0.01M Cobalt Chloride
|
Resolution 1.48 Å R-free 0.213 |
| 9J1B Structure of ConA/IMI-Man Deposited 2024-08-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 A1EAT ~{N}-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethyl]-4-[3-[4-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethylcarbamoyl]phenyl]imidazol-3-ium-1-yl]benzamide × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；buffer: 20 mM HEPES, 5 mM CaCl2, 5 mM MnCl2; pH = 7.2, precipitant: Ammonium phosphate
|
Resolution 2.48 Å R-free 0.228 |
| 9J1C Structure of ConA/NAP-Man Deposited 2024-08-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 4 CA CALCIUM ION × 4 A1EAU ~{N}2,~{N}6-bis[2-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethoxy]ethyl]naphthalene-2,6-dicarboxamide × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；0.1 M MES monohydrate pH 6.5, 12 % w/v Polyethylene glycol 20,000
|
Resolution 2.43 Å R-free 0.282 |
| 9J1D Structure of ConA/PHE-Man Deposited 2024-08-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
|
Not recorded | A1EAW ~{N}2,~{N}9-bis[2-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethoxy]ethyl]-1,10-phenanthroline-2,9-dicarboxamide × 2 CA CALCIUM ION × 4 MN MANGANESE (II) ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；0.1M Tris-HCl pH 8.5, 2.0M Ammonium phosphate monobasic
|
Resolution 3.49 Å R-free 0.229 |
| 9J1F Dimeric Structure of ConA/M2P-Man Deposited 2024-08-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
164–281（118 aa）
Chain A
30–148（119 aa）
Chain D
164–281（118 aa）
Chain D
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；0.2M Sodium chloride, 0.1M Phosphate-citrate pH 4.2 10% (w/v) PEG 3000
|
Resolution 2.17 Å R-free 0.257 |
| 9J1F Dimeric Structure of ConA/M2P-Man Deposited 2024-08-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
164–281（118 aa）
Chain B
30–148（119 aa）
Chain C
164–281（118 aa）
Chain C
30–148（119 aa）
|
Not recorded | MN MANGANESE (II) ION × 2 CA CALCIUM ION × 2 A1EAW ~{N}2,~{N}9-bis[2-[2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyethoxy]ethyl]-1,10-phenanthroline-2,9-dicarboxamide × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；0.2M Sodium chloride, 0.1M Phosphate-citrate pH 4.2 10% (w/v) PEG 3000
|
Resolution 2.17 Å R-free 0.257 |
72 other PDB entries and 89 assemblies. Open the comparison page and filter oligomeric states
View Construct and Data Evidence
| UniProt name | CONA_CANEN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–118； UniProt 164–281 Author chain A； PDBConstruct 119–237； UniProt 30–148 |
