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6mx4

CryoEM structure of chimeric Eastern Equine Encephalitis Virus

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

E1

Eastern equine encephalitis virus

UniProt E9KXM2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 720 其他Polymer 240 E2 × 240 （E9KXL2） Capsid × 240 （P27284） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 240 2-acetamido-2-deoxy-beta-D-glucopyranose × 240 Consistent with protein count
2 Other combination Heteromer Protein 12 其他Polymer 4 E2 × 4 （E9KXL2） Capsid × 4 （P27284） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 Consistent with protein count
3 Other combination Heteromer Protein 60 其他Polymer 20 E2 × 20 （E9KXL2） Capsid × 20 （P27284） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 20 2-acetamido-2-deoxy-beta-D-glucopyranose × 20 Consistent with protein count
4 Other combination Heteromer Protein 72 其他Polymer 24 E2 × 24 （E9KXL2） Capsid × 24 （P27284） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 24 2-acetamido-2-deoxy-beta-D-glucopyranose × 24 Consistent with protein count
5 Other combination Heteromer Protein 12 其他Polymer 4 E2 × 4 （E9KXL2） Capsid × 4 （P27284） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6mui 6mui 6mui 6mui 6mui 6mw9 6mw9 6mw9 6mw9 6mw9 6mwc 6mwc

38 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name E9KXM2_EEEV
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–441； UniProt 802–1242 Author chain D； PDBConstruct 1–441； UniProt 802–1242 Author chain G； PDBConstruct 1–441； UniProt 802–1242 Author chain J； PDBConstruct 1–441； UniProt 802–1242

E2

Eastern equine encephalitis virus

UniProt E9KXL2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 720 其他Polymer 240 E1 × 240 （E9KXM2） Capsid × 240 （P27284） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 240 2-acetamido-2-deoxy-beta-D-glucopyranose × 240 Consistent with protein count
2 Other combination Heteromer Protein 12 其他Polymer 4 E1 × 4 （E9KXM2） Capsid × 4 （P27284） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 Consistent with protein count
3 Other combination Heteromer Protein 60 其他Polymer 20 E1 × 20 （E9KXM2） Capsid × 20 （P27284） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 20 2-acetamido-2-deoxy-beta-D-glucopyranose × 20 Consistent with protein count
4 Other combination Heteromer Protein 72 其他Polymer 24 E1 × 24 （E9KXM2） Capsid × 24 （P27284） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 24 2-acetamido-2-deoxy-beta-D-glucopyranose × 24 Consistent with protein count
5 Other combination Heteromer Protein 12 其他Polymer 4 E1 × 4 （E9KXM2） Capsid × 4 （P27284） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6mui 6mui 6mui 6mui 6mui 6mw9 6mw9 6mw9 6mw9 6mw9 6mwc 6mwc

39 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name E9KXL2_EEEV
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–420； UniProt 325–744 Author chain E； PDBConstruct 1–420； UniProt 325–744 Author chain H； PDBConstruct 1–420； UniProt 325–744 Author chain K； PDBConstruct 1–420； UniProt 325–744

Capsid

Eastern equine encephalitis virus

UniProt P27284

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 720 其他Polymer 240 E1 × 240 （E9KXM2） E2 × 240 （E9KXL2） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 240 2-acetamido-2-deoxy-beta-D-glucopyranose × 240 Consistent with protein count
2 Other combination Heteromer Protein 12 其他Polymer 4 E1 × 4 （E9KXM2） E2 × 4 （E9KXL2） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 Consistent with protein count
3 Other combination Heteromer Protein 60 其他Polymer 20 E1 × 20 （E9KXM2） E2 × 20 （E9KXL2） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 20 2-acetamido-2-deoxy-beta-D-glucopyranose × 20 Consistent with protein count
4 Other combination Heteromer Protein 72 其他Polymer 24 E1 × 24 （E9KXM2） E2 × 24 （E9KXL2） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 24 2-acetamido-2-deoxy-beta-D-glucopyranose × 24 Consistent with protein count
5 Other combination Heteromer Protein 12 其他Polymer 4 E1 × 4 （E9KXM2） E2 × 4 （E9KXL2） ;2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 4 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer
6mx7 6mx7

2 assemblies

Other homooligomers
6mx7 6mx7 6mx7

3 assemblies

Heteromeric or nucleic-acid complex
6mx4 6mx4 6mx4 6mx4 6mx4

5 assemblies

View Construct and Data Evidence
UniProt name POLS_EEEV3
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 1–260； UniProt 1–260 Author chain F； PDBConstruct 1–260； UniProt 1–260 Author chain I； PDBConstruct 1–260； UniProt 1–260 Author chain L； PDBConstruct 1–260； UniProt 1–260

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6mx4
Deposition date deposition_date2018-10-30
Structure title titleCryoEM structure of chimeric Eastern Equine Encephalitis Virus
Keywords keywordsAlphavirus, EEEV, Eastern Equine Encephalitis Virus, Sindbis, VIRUS; VIRUS
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6mx4__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6mx4__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 1012 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6mx4__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)260.20 Å
Total Rg260.20 Å
Atom count1889460
Residues242340
Excluded volume33574000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6mx4__assembly_1__model_1 720-meric （720） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6mx4__assembly_2__model_1 dodecameric （12） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 6mx4__assembly_3__model_1 60-meric （60） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 6mx4__assembly_4__model_1 72-meric （72） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 6mx4__assembly_5__model_1 dodecameric （12） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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7. Citations (1)