Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | ITSM × 1 | Consistent with protein count |
| UniProt name | PTN11_HUMAN |
| Isoform | Q06124-2 |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 4–119； UniProt 105–220 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 6r5g |
| Deposition date deposition_date | 2019-03-25 |
| Structure title title | C-SH2 domain of SHP-2 in complex with phospho-ITSM of PD-1 |
| Keywords keywords | SHP-2 C-SH2 ITSM SH2 domain PD-1 phosphotyrosine, PEPTIDE BINDING PROTEIN; PEPTIDE BINDING PROTEIN |
| Experimental Method method | SOLUTION NMR |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 15.21 Å |
| Rg (electron density) | 13.77 Å |
| Total Rg | 15.06 Å |
| Atom count | 2039 |
| Residues | 129 |
| Excluded volume | 18096 ų |
| Maximum q | 0.500 Å⁻¹ |
| Assembly | Model | Structure unit | Oligomeric description | Status | CRYSOL | Actions |
|---|---|---|---|---|---|---|
| 1 | 1 | 6r5g__assembly_1__model_1 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 2 | 6r5g__assembly_1__model_2 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 3 | 6r5g__assembly_1__model_3 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 4 | 6r5g__assembly_1__model_4 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 5 | 6r5g__assembly_1__model_5 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 6 | 6r5g__assembly_1__model_6 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 7 | 6r5g__assembly_1__model_7 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 8 | 6r5g__assembly_1__model_8 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 9 | 6r5g__assembly_1__model_9 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 10 | 6r5g__assembly_1__model_10 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| Domain ID domain_id | 6r5gA00 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 505 — SHC Adaptor Protein |
| Homologous superfamily homologous superfamily | 10 — SH2 domain |