9z70
Crystal structure of shorter construct of SHP2 unbound N-SH2 domain (Y66 in blocking conformation)
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 9z70 |
| deposition_date | 2025-11-14 |
| last_revision | 2026-01-07 |
| title | Crystal structure of shorter construct of SHP2 unbound N-SH2 domain (Y66 in blocking conformation) |
| keywords | SHP2, phosphatase, SH2, allostery, PROTEIN BINDING; PROTEIN BINDING |
| method | X-RAY DIFFRACTION |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 14.38 Å |
| rg_electron | 12.78 Å |
| i0 | 2973100.00 |
| molecular_weight | 11794.0 kDa |
| excluded_volume | 14686 ų |
| envelope_volume | 16297 ų |
| shell_volume | 10895 ų |
| envelope_diameter | 42.1 Å |
| shell_rg | 18.49 Å |
| envelope_rg | 12.99 Å |
| shape_rg | 12.76 Å |
| total_rg | 14.12 Å |
| total_atoms | 1645 |
| n_residues | 104 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 43.1 Å |
| rg_real | 14.26 Å |
| rg_real_error | 0.20 Å |
| i0_real | 2.9730e+06 |
| i0_real_error | 3.2660e+04 |
| rg_reciprocal | 14.27 Å |
| i0_reciprocal | 2973000.0000 |
| total_estimate | 0.7246 |
| solution_quality | REASONABLE a REASONABLE solution |
| n_peaks | 1 |
| r_peak_primary | 42.0 Å |
| skewness | -0.018 |
| kurtosis | -0.432 |
| angular_range | — – 0.5000 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 502000.0000 |
| n_real_points | 80 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.897; Stabil: 1.000; Sysdev: 0.256; Positv: 1.000; Valcen: 0.975; Smooth: 0.980 |