9qa5
Structure of the N-SH2 domain of SHP2 in complex with the phosphoY627-Gab1 (613-651) peptide
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 9qa5 |
| deposition_date | 2025-02-27 |
| title | Structure of the N-SH2 domain of SHP2 in complex with the phosphoY627-Gab1 (613-651) peptide |
| keywords | SH2-domain, phosphatase, PTPN11, phospho-tyrosine, SIGNALING PROTEIN; SIGNALING PROTEIN |
| method | X-RAY DIFFRACTION |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 14.40 Å |
| rg_electron | 12.80 Å |
| i0 | 3166530.00 |
| molecular_weight | 12322.0 kDa |
| excluded_volume | 15372 ų |
| envelope_volume | 16895 ų |
| shell_volume | 11178 ų |
| envelope_diameter | 43.5 Å |
| shell_rg | 18.59 Å |
| envelope_rg | 13.07 Å |
| shape_rg | 12.78 Å |
| total_rg | 14.13 Å |
| total_atoms | 870 |
| n_residues | 107 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 44.7 Å |
| rg_real | 14.28 Å |
| rg_real_error | 0.20 Å |
| i0_real | 3.1670e+06 |
| i0_real_error | 3.1840e+04 |
| rg_reciprocal | 14.29 Å |
| i0_reciprocal | 3167000.0000 |
| total_estimate | 0.8907 |
| solution_quality | GOOD a GOOD solution |
| n_peaks | 1 |
| r_peak_primary | 44.1 Å |
| skewness | 0.020 |
| kurtosis | -0.410 |
| angular_range | — – 0.5000 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 555600.0000 |
| n_real_points | 80 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.870; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.986; Smooth: 0.978 |