← Back to search
7wpp

Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 2.85 angstron resolution (1 unit)

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

von Willebrand antigen 2

Homo sapiens

UniProt P04275

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 4 CALCIUM ION × 6 2-acetamido-2-deoxy-beta-D-glucopyranose × 10 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1ao3 1ao3 1atz 1atz 1auq 1ijb 2mhp 2mhq 3ppv 3ppw 3ppx 3ppy

22 assemblies; showing the first 12

Homodimer
4nt5

1 assemblies

Homotetramer
7wn4 7wpp

2 assemblies

Other homooligomers
7wn3 7wn6 7wpq 7wpr 7wps 7wqt 8d3c 8d3d

8 assemblies

Heteromeric or nucleic-acid complex
1fe8 1fe8 1fe8 1fe8 1fns 1ijk 1m10 1oak 1sq0 1u0n 1uex 2adf

32 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name VWF_HUMAN
Isoform —
PDB entities 1, 2
Chains and sequence ranges Author chain E； PDBConstruct 1–741； UniProt 23–763 Author chain G； PDBConstruct 1–741； UniProt 23–763 Author chain F； PDBConstruct 1–478； UniProt 764–1241 Author chain H； PDBConstruct 1–478； UniProt 764–1241

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id7wpp
Deposition date deposition_date2022-01-24
Structure title titleCryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 2.85 angstron resolution (1 unit)
Keywords keywords;blood, VWF, von Willebrand factor, von Willebrand disease, blood coagulation, blood clotting, multimer assembly, VWF assembly, D'D3 domain, D1D2 domain, D'D3 dimer, D1D2 Dimer, VWF Tube, repeating unit ;; BLOOD CLOTTING
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7wpp__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7wpp__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7wpp__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）46.75 Å
Rg (electron density)46.17 Å
Total Rg46.50 Å
Atom count18246
Residues2372
Excluded volume320390 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7wpp__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (4)

▶

7. Citations (1)