SAXSdb — 7wpr

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1. Protein Identity and Related Structures Protein Identity & Related Structures

von Willebrand antigen 2

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 32	2-acetamido-2-deoxy-beta-D-glucopyranose × 42 CALCIUM ION × 56	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	VWF_HUMAN
Isoform	—
PDB entities	1, 2
Chains and sequence ranges	Author chain A； PDBConstruct 1–741； UniProt 23–763 Author chain B； PDBConstruct 1–741； UniProt 23–763 Author chain E； PDBConstruct 1–741； UniProt 23–763 Author chain F； PDBConstruct 1–741； UniProt 23–763 Author chain G； PDBConstruct 1–741； UniProt 23–763 Author chain H； PDBConstruct 1–741； UniProt 23–763 Author chain I； PDBConstruct 1–741； UniProt 23–763 Author chain J； PDBConstruct 1–741； UniProt 23–763 Author chain K； PDBConstruct 1–741； UniProt 23–763 Author chain L； PDBConstruct 1–741； UniProt 23–763 Author chain M； PDBConstruct 1–741； UniProt 23–763 Author chain N； PDBConstruct 1–741； UniProt 23–763 Author chain O； PDBConstruct 1–741； UniProt 23–763 Author chain P； PDBConstruct 1–741； UniProt 23–763 Author chain Q； PDBConstruct 1–741； UniProt 23–763 Author chain R； PDBConstruct 1–741； UniProt 23–763 Author chain C； PDBConstruct 1–478； UniProt 764–1241 Author chain D； PDBConstruct 1–478； UniProt 764–1241 Author chain S； PDBConstruct 1–478； UniProt 764–1241 Author chain T； PDBConstruct 1–478； UniProt 764–1241 Author chain U； PDBConstruct 1–478； UniProt 764–1241 Author chain V； PDBConstruct 1–478； UniProt 764–1241 Author chain W； PDBConstruct 1–478； UniProt 764–1241 Author chain X； PDBConstruct 1–478； UniProt 764–1241 Author chain Y； PDBConstruct 1–478； UniProt 764–1241 Author chain Z； PDBConstruct 1–478； UniProt 764–1241 Author chain a； PDBConstruct 1–478； UniProt 764–1241 Author chain b； PDBConstruct 1–478； UniProt 764–1241 Author chain c； PDBConstruct 1–478； UniProt 764–1241 Author chain d； PDBConstruct 1–478； UniProt 764–1241 Author chain e； PDBConstruct 1–478； UniProt 764–1241 Author chain f； PDBConstruct 1–478； UniProt 764–1241

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	7wpr
Deposition date deposition_date	2022-01-24
Structure title title	VWF D'D3 dimer complexed with D1D2 at 4.39 angstron resolution(VWF tube)
Keywords keywords	;blood, VWF, von Willebrand factor, von Willebrand disease, blood coagulation, blood clotting, multimer assembly, VWF assembly, D'D3 domain, D1D2 domain, D'D3 dimer, D1D2 Dimer, VWF Tube, repeating unit ;; BLOOD CLOTTING
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7wpr__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7wpr__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

7wpr__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	0.00 Å
Rg (electron density)	118.50 Å
Total Rg	118.60 Å
Atom count	145668
Residues	19024
Excluded volume	2558100 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`7wpr__assembly_1__model_1`	32-meric （32）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Description description	von Willebrand antigen 2
Molecular weight formula_weight	81427.7 kDa
Source method src_method	man
Copy count entity_count	16

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,E,F,G,H,I,J,K,L,M,N,O,P,Q,R
Atom count atom_count	145764

AEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKR

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 2 Entity 2 polymer

Description description	von Willebrand factor
Molecular weight formula_weight	54232.8 kDa
Source method src_method	man
Copy count entity_count	16

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	a,b,C,c,D,d,e,f,S,T,U,V,W,X,Y,Z

SLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCQDRKWNCTDHVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVPPHHHHHH

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Entity 3 Entity 3 non-polymer

Description description	2-acetamido-2-deoxy-beta-D-glucopyranose
Molecular weight formula_weight	221.2 kDa
Source method src_method	man
Copy count entity_count	42

Entity 4 Entity 4 non-polymer

Description description	CALCIUM ION
Molecular weight formula_weight	40.1 kDa
Source method src_method	syn
Copy count entity_count	56

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	4.39 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	323041

VWF D'D3 dimer complexed with D1D2 at 4.39 angstron resolution(VWF tube)

1. Protein Identity and Related Structures Protein Identity & Related Structures

von Willebrand antigen 2

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

7wpr__assembly_1__model_1

7wpr__assembly_1__model_1 | I(q)

7wpr__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

7. Citations (1)

VWF D'D3 dimer complexed with D1D2 at 4.39 angstron resolution(VWF tube)

1. Protein Identity and Related Structures Protein Identity & Related Structures

von Willebrand antigen 2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

7wpr__assembly_1__model_1

7wpr__assembly_1__model_1 | I(q)

7wpr__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

7. Citations (1)