7z13

S. cerevisiae CMGE dimer nucleating origin DNA melting

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA replication licensing factor MCM2

Saccharomyces cerevisiae

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A6A5Q1S9_YEASX
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain 2； PDBConstruct 1–868； UniProt 1–868 Author chain a； PDBConstruct 1–868； UniProt 1–868

DNA replication licensing factor MCM3

Saccharomyces cerevisiae

UniProt P24279

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MCM3_YEAST
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain 3； PDBConstruct 36–1006； UniProt 1–971 Author chain b； PDBConstruct 36–1006； UniProt 1–971

DNA replication licensing factor MCM4

Saccharomyces cerevisiae

UniProt P30665

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MCM4_YEAST
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain 4； PDBConstruct 1–933； UniProt 1–933 Author chain c； PDBConstruct 1–933； UniProt 1–933

DNA helicase

Saccharomyces cerevisiae

UniProt A0A6A5PUY8

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A6A5PUY8_YEASX
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain 5； PDBConstruct 1–775； UniProt 1–775 Author chain d； PDBConstruct 1–775； UniProt 1–775

DNA replication licensing factor MCM6

Saccharomyces cerevisiae

UniProt P53091

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MCM6_YEAST
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain 6； PDBConstruct 1–1017； UniProt 1–1017 Author chain e； PDBConstruct 1–1017； UniProt 1–1017

DNA replication licensing factor MCM7

Saccharomyces cerevisiae

UniProt A0A6A5Q4N0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A6A5Q4N0_YEASX
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain 7； PDBConstruct 1–845； UniProt 1–845 Author chain f； PDBConstruct 1–845； UniProt 1–845

DNA replication complex GINS protein PSF3

Saccharomyces cerevisiae

UniProt Q12146

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	PSF3_YEAST
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain C； PDBConstruct 36–229； UniProt 1–194 Author chain J； PDBConstruct 36–229； UniProt 1–194

DNA replication complex GINS protein SLD5

Saccharomyces cerevisiae

UniProt Q03406

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	SLD5_YEAST
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain D； PDBConstruct 1–294； UniProt 1–294 Author chain K； PDBConstruct 1–294； UniProt 1–294

Cell division control protein 45

Saccharomyces cerevisiae

UniProt Q08032

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	CDC45_YEAST
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain E； PDBConstruct 1–198； UniProt 1–198 Author chain E； PDBConstruct 210–657； UniProt 203–650 Author chain L； PDBConstruct 1–198； UniProt 1–198 Author chain L； PDBConstruct 210–657； UniProt 203–650

DNA polymerase epsilon subunit B

Saccharomyces cerevisiae

UniProt P24482

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	DPB2_YEAST
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain F； PDBConstruct 1–689； UniProt 1–689 Author chain M； PDBConstruct 1–689； UniProt 1–689

DNA replication complex GINS protein PSF1

Saccharomyces cerevisiae

UniProt A0A6A5Q203

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A6A5Q203_YEASX
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain H； PDBConstruct 1–208； UniProt 1–208 Author chain O； PDBConstruct 1–208； UniProt 1–208

DNA replication complex GINS protein PSF2

Saccharomyces cerevisiae

UniProt A0A6A5PX40

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA polymerase epsilon catalytic subunit A × 2 （P21951） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A6A5PX40_YEASX
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain I； PDBConstruct 1–213； UniProt 1–213 Author chain P； PDBConstruct 1–213； UniProt 1–213

DNA polymerase epsilon catalytic subunit A

Saccharomyces cerevisiae

UniProt P21951

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Heteromer	Protein 26 DNA 2	DNA replication licensing factor MCM2 × 2 （A0A6A5Q1S9） DNA replication licensing factor MCM3 × 2 （P24279） DNA replication licensing factor MCM4 × 2 （P30665） DNA helicase × 2 （A0A6A5PUY8） DNA replication licensing factor MCM6 × 2 （P53091） DNA replication licensing factor MCM7 × 2 （A0A6A5Q4N0） DNA (53-MER) × 1 DNA (53-MER) × 1 DNA replication complex GINS protein PSF3 × 2 （Q12146） DNA replication complex GINS protein SLD5 × 2 （Q03406） Cell division control protein 45 × 2 （Q08032） DNA polymerase epsilon subunit B × 2 （P24482） DNA replication complex GINS protein PSF1 × 2 （A0A6A5Q203） DNA replication complex GINS protein PSF2 × 2 （A0A6A5PX40） ADENOSINE-5'-TRIPHOSPHATE × 8 ZINC ION × 14 MAGNESIUM ION × 6 ADENOSINE-5'-DIPHOSPHATE × 4	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	DPOE_YEAST
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain N； PDBConstruct 1–2222； UniProt 1–2222 Author chain Q； PDBConstruct 1–2222； UniProt 1–2222

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	7z13
Deposition date deposition_date	2022-02-24
Structure title title	S. cerevisiae CMGE dimer nucleating origin DNA melting
Keywords keywords	DNA replication, helicase, initiation, DNA origin, REPLICATION; REPLICATION
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7z13__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7z13__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

7z13__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	97.21 Å
Rg (electron density)	99.30 Å
Total Rg	99.06 Å
Atom count	107381
Residues	13234
Excluded volume	1913400 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`7z13__assembly_1__model_1`	28-meric （28）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (19)

Entity 1 Entity 1 polymer

Description description	DNA replication licensing factor MCM2
Molecular weight formula_weight	98911.5 kDa
EC 编号 ec_number	3.6.4.12
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	2,a
Atom count atom_count	107381

MSDNRRRRREEDDSDSENELPPSSPQQHFRGGMNPVSSPIGSPDMINPEGDDNEVDDVPDIDEVEEQMNEVDLMDDNMYEDYAADHNRDRYDPDQVDDREQQELSLSERRRIDAQLNERDRLLRNVAYIDDEDEEQEGAAQLDEMGLPVQRRRRRRQYEDLENSDDDLLSDMDIDPLREELTLESLSNVKANSYSEWITQPNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEIRISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPVFATIIEANSIKRREGNTANEGEEGLDVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENDEDREGEELKNNGESAIEQGEDEINEQLNARQRRLQRQRKKEEEISPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQLRRSFAIYTLGH

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Saccharomyces cerevisiae

Entity 2 Entity 2 polymer

Description description	DNA replication licensing factor MCM3
Molecular weight formula_weight	111720.2 kDa
EC 编号 ec_number	3.6.4.12
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	3,b

MKRRWKKNFIAVSAANRFKKISSSGALENLYFQGEMEGSTGFDGDATTFFAPDAVFGDRVRRFQEFLDTFTSYRDSVRSIQVYNSNNAANYNDDQDDADERDLLGDDDGDDLEKEKKAASSTSLNILPHRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPWKLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTPAIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALLGEDIGNDIDEEESEYEEALSKRSPQKSPKKRQRVRQPASNSGSPIKSTPRRSTASSVNATPSSARRILRFQDDEQNAGEDDNDIMSPLPADEEAELQRRLQLGLRVSPRRREHLHAPEEGSSGPLTEVGTPRLPNVSSAGQDDEQQQSVISFDNVEPGTISTGRLSLISGIIARLMQTEIFEEESYPVASLFERINEELPEEEKFSAQEYLAGLKIMSDRNNLMVADDKVWRV

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Saccharomyces cerevisiae

Entity 3 Entity 3 polymer

Description description	DNA replication licensing factor MCM4
Molecular weight formula_weight	105138.4 kDa
EC 编号 ec_number	3.6.4.12
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	4,c

MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEGNIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSSSSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRIIWGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVESSDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Saccharomyces cerevisiae

Entity 4 Entity 4 polymer

Description description	DNA helicase
Molecular weight formula_weight	86505.7 kDa
EC 编号 ec_number	3.6.4.12
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	5,d

MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELKRRLPIGWSTSYQTLRREFVDTHRFSQLALDKALYALEKHETIQLRHQGQNIYRSGV

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Saccharomyces cerevisiae

Entity 5 Entity 5 polymer

Description description	DNA replication licensing factor MCM6
Molecular weight formula_weight	113110.2 kDa
EC 编号 ec_number	3.6.4.12
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	6,e

MSSPFPADTPSSNRPSNSSPPPSSIGAGFGSSSGLDSQIGSRLHFPSSSQPHVSNSQTGPFVNDSTQFSSQRLQTDGSATNDMEGNEPARSFKSRALNHVKKVDDVTGEKVREAFEQFLEDFSVQSTDTGEVEKVYRAQIEFMKIYDLNTIYIDYQHLSMRENGALAMAISEQYYRFLPFLQKGLRRVVRKYAPELLNTSDSLKRSEGDEGQADEDEQQDDDMNGSSLPRDSGSSAAPGNGTSAMATRSITTSTSPEQTERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPDVTQLGLPGVKPSSTLDTRGISKTTEGLNSGVTGLRSLGVRDLTYKISFLACHVISIGSNIGASSPDANSNNRETELQMAANLQANNVYQDNERDQEVFLNSLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAVVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLHMKRDEAIEPPFSAEQLRRYIKYARTFKPILTKEARSYLVEKYKELRKDDAQGFSRSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRVDVDDVEMDEEFDNIESQSHAASGNNDDNDDGTGSGVITSEPPADIEEGQSEATARPGTSEKKKTTVTYDKYVSMMNMIVRKIAEVDREGAEELTAVDIVDWYLLQKENDLGSLAEYWEERRLAFKVIKRLVKDRILMEIHGTRHNLRDLENEENENNKTVYVIHPNCEVLDQLEPQDSS

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Saccharomyces cerevisiae

Entity 6 Entity 6 polymer

Description description	DNA replication licensing factor MCM7
Molecular weight formula_weight	95049.9 kDa
EC 编号 ec_number	3.6.4.12
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	7,f

MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKGPKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRAIDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDALREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLSNCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDIDLQDA

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Saccharomyces cerevisiae

Entity 7 Entity 7 polymer

Description description	DNA (53-MER)
Molecular weight formula_weight	16320.6 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer Polymer

Polymer type type	polydeoxyribonucleotide
Chain IDs strand_id	A

TTTTTTTTTTTTTTTTTTTTTTTTTTAAAAAAAAAAAAAAAAAAAAAAAAAAA

Entity 8 Entity 8 polymer

Description description	DNA (53-MER)
Molecular weight formula_weight	16311.6 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer Polymer

Polymer type type	polydeoxyribonucleotide
Chain IDs strand_id	B

TTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAAAAAAAAAAAAAAAAAAAAAAA

Entity 9 Entity 9 polymer

Description description	DNA replication complex GINS protein PSF3
Molecular weight formula_weight	25718.1 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C,J

WSHPQFEKGGGSGGGSGGGSWSHPQFEKENLYFQSMGYYDIDDVLADGTEFPCKFQYDIPGLGYLENNPGRPITKNTKLSLPLWLARILAIVGGDEALVDEEPVPFVELLPPDMFSTKVMNAIKTDPVALDLHSINSHFFSLAIKWIMLFSEKELANVVSELLLQRAQELNHHASSLSIDLNADSTGKNSANTNIATSTFLLKLEEMEKEIYKKSHESYKDTKRWMFKK

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Escherichia coli

Entity 10 Entity 10 polymer

Description description	DNA replication complex GINS protein SLD5
Molecular weight formula_weight	33983.6 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D,K

MDINIDDILAELDKETTAVDSTKITQGSSSTTHRDANTIVGSSLDLNDKTQIYVSPQQDFSDLMKSWKNERCSPELLPYPHQLMKRLLNRISMQSQLIENISMGFLDMQNASNANPPMPNESKLPLLCMETELERLKFVIRSYIRCRLSKIDKFSLYLRQLNEDENSLISLTDLLSKDEIKYHDTHSLIWLKLVNDSILKYMPEELQAINDTEGSVNMIDEPDWNKFVFIHVNGPPDGKWNEDPLLQENEFGKPCYTVTIPDLKEEVELTIGSIYVMRYEVIRDLLRDDKVALI

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Escherichia coli

Entity 11 Entity 11 polymer

Description description	Cell division control protein 45
Molecular weight formula_weight	75154.7 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E,L

MYYGISQFSEAYNKILRNSSSHSSCQLVIFVSCLNIDALCATKMLSLLFKKQLVQSQIVPIFGYSELRRHYSQLDDNINSLLLVGFGGVIDLEAFLEIDPQEYVIDTDEKSGEQSFRRDIYVLDAHRPWNLDNIFGSQIIQCFDDGTVDDTLGEQKEAYYKLLELDEESGDDELSGDENDNNGGDDEATDADEVTDEDYKDDDGDYKDDDETISNKRGNSSIGPNDLSKRKQRKKQIHEYEGVLEEYYSQGTTVVNSISAQIYSLLSAIGETNLSNLWLNILGTTSLDIAYAQVYNRLYPLLQDEVKRLTPSSRNSVKTPDTLTLNIQPDYYLFLLRHSSLYDSFYYSNYVNAKLSLWNENGKKRLHKMFARMGIPLSTAQETWLYMDHSIKRELGIIFDKNLDRYGLQDIIRDGFVRTLGYRGSISASEFVEALTALLEVGNSTDKDSVKINNDNNDDTDGEEEEDNSAQKLTNLRKRWVSNFWLSWDALDDRKVELLNRGIQLAQDLQRAIFNTGVAILEKKLIKHLRIYRLCVLQDGPDLDLYRNPLTLLRLGNWLIECCAESEDKQLLPMVLASIDENTDTYLVAGLTPRYPRGLDTIHTKKPILNNFSMAFQQITAETDAKVRIDNFESSIIEIRREDLSPFLEKLTLSGLL

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Saccharomyces cerevisiae

Entity 12 Entity 12 polymer

Description description	DNA polymerase epsilon subunit B
Molecular weight formula_weight	78425.9 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F,M

MFGSGNVLPVKIQPPLLRPLAYRVLSRKYGLSIKSDGLSALAEFVGTNIGANWRQGPATIKFLEQFAAVWKQQERGLFIDQSGVKEVIQEMKEREKVEWSHEHPIQHEENILGRTDDDENNSDDEMPIAADSSLQNVSLSSPMRQPTERDEYKQPFKPESSKALDWRDYFKVINASQQQRFSYNPHKMQFIFVPNKKQNGLGGIAGFLPDIEDKVQMFLTRYYLTNDRVMRNENFQNSDMFNPLSSMVSLQNELSNTNRQQQSSSMSITPIKNLLGRDAQNFLLLGLLNKNFKGNWSLEDPSGSVEIDISQTIPTQGHYYVPGCMVLVEGIYYSVGNKFHVTSMTLPPGERREITLETIGNLDLLGIHGISNNNFIARLDKDLKIRLHLLEKELTDHKFVILGANLFLDDLKIMTALSKILQKLNDDPPTLLIWQGSFTSVPVFASMSSRNISSSTQFKNNFDALATLLSRFDNLTENTTMIFIPGPNDLWGSMVSLGASGTLPQDPIPSAFTKKINKVCKNVVWSSNPTRIAYLSQEIVIFRDDLSGRFKRHRLEFPFNESEDVYTENDNMMSKDTDIVPIDELVKEPDQLPQKVQETRKLVKTILDQGHLSPFLDSLRPISWDLDHTLTLCPIPSTMVLCDTTSAQFDLTYNGCKVINPGSFIHNRRARYMEYVPSSKKTIQEEIYI

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Saccharomyces cerevisiae

Entity 13 Entity 13 polymer

Description description	DNA replication complex GINS protein PSF1
Molecular weight formula_weight	24230.6 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H,O

MYGDLGNKLVLEAKRTKQLYARSNQDVNLPMYHEDIIRNILKEVSNLRKNTEYLKEQQQLGMLDDKVAKCQYFVTLLCMERNKRCLLAYQRLRTDILDSMAWNNNGLDLMSSITFSQQDTNNLSHQEQEYLKEYCDLITDLKSGDLVDIDLSGSLVPPSDVFIDVRVLKDAGEIQTEYGVFNLIKDSQFFVRQSDVERLIQQGYLQKI

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Escherichia coli

Entity 14 Entity 14 polymer

Description description	DNA replication complex GINS protein PSF2
Molecular weight formula_weight	25096.8 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I,P

MSLPAHLQQTFSPEEIQFIVENEPIKIFPRITTRQKIRGDDRGTGNHTRWQLITTDDKALNNMVAMRSTEVVLWIALLLKQQSKCSIVAPQWLTTKELDRKIQYEKTHPDRFSELPWNWLVLARILFNKAKDDFHDPIHELRGKIQDLREIRQIKVLKGLKYLNESHLQLDNLSLLEINELRPFITEIMDKLREIHTASLTAGTENDEEEFNI

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Escherichia coli

Entity 15 Entity 15 polymer

Description description	DNA polymerase epsilon catalytic subunit A
Molecular weight formula_weight	255992.5 kDa
EC 编号 ec_number	2.7.7.7,3.1.11.-
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N,Q

MMFGKKKNNGGSSTARYSAGNKYNTLSNNYALSAQQLLNASKIDDIDSMMGFERYVPPQYNGRFDAKDIDQIPGRVGWLTNMHATLVSQETLSSGSNGGGNSNDGERVTTNQGISGVDFYFLDEEGGSFKSTVVYDPYFFIACNDESRVNDVEELVKKYLESCLKSLQIIRKEDLTMDNHLLGLQKTLIKLSFVNSNQLFEARKLLRPILQDNANNNVQRNIYNVAANGSEKVDAKHLIEDIREYDVPYHVRVSIDKDIRVGKWYKVTQQGFIEDTRKIAFADPVVMAFDIETTKPPLKFPDSAVDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKPEYPGFFTIFNENDEVALLQRFFEHIRDVRPTVISTFNGDFFDWPFIHNRSKIHGLDMFDEIGFAPDAEGEYKSSYCSHMDCFRWVKRDSYLPQGSQGLKAVTQSKLGYNPIELDPELMTPYAFEKPQHLSEYSVSDAVATYYLYMKYVHPFIFSLCTIIPLNPDETLRKGTGTLCEMLLMVQAYQHNILLPNKHTDPIERFYDGHLLESETYVGGHVESLEAGVFRSDLKNEFKIDPSAIDELLQELPEALKFSVEVENKSSVDKVTNFEEIKNQITQKLLELKENNIRNELPLIYHVDVASMYPNIMTTNRLQPDSIKAERDCASCDFNRPGKTCARKLKWAWRGEFFPSKMDEYNMIKRALQNETFPNKNKFSKKKVLTFDELSYADQVIHIKKRLTEYSRKVYHRVKVSEIVEREAIVCQRENPFYVDTVKSFRDRRYEFKGLAKTWKGNLSKIDPSDKHARDEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGATIIQMARALVERVGRPLELDTDGIWCILPKSFPETYFFTLENGKKLYLSYPCSMLNYRVHQKFTNHQYQELKDPLNYIYETHSENTIFFEVDGPYKAMILPSSKEEGKGIKKRYAVFNEDGSLAELKGFELKRRGELQLIKNFQSDIFKVFLEGDTLEGCYSAVASVCNRWLDVLDSHGLMLEDEDLVSLICENRSMSKTLKEYEGQKSTSITTARRLGDFLGEDMVKDKGLQCKYIISSKPFNAPVTERAIPVAIFSADIPIKRSFLRRWTLDPSLEDLDIRTIIDWGYYRERLGSAIQKIITIPAALQGVSNPVPRVEHPDWLKRKIATKEDKFKQTSLTKFFSKTKNVPTMGKIKDIEDLFEPTVEEDNAKIKIARTTKKKAVSKRKRNQLTNEEDPLVLPSEIPSMDEDYVGWLNYQKIKWKIQARDRKRRDQLFGNTNSSRERSALGSMIRKQAESYANSTWEVLQYKDSGEPGVLEVFVTINGKVQNITFHIPKTIYMKFKSQTMPLQKIKNCLIEKSSASLPNNPKTSNPAGGQLFKITLPESVFLEEKENCTSIFNDENVLGVFEGTITPHQRAIMDLGASVTFRSKAMGALGKGIQQGFEMKDLSMAENERYLSGFSMDIGYLLHFPTSIGYEFFSLFKSWGDTITILVLKPSNQAQEINASSLGQIYKQMFEKKKGKIETYSYLVDIKEDINFEFVYFTDISKLYRRLSQETTKLKEERGLQFLLLLQSPFITKLLGTIRLLNQMPIVKLSLNEVLLPQLNWQPTLLKKLVNHVLSSGSWISHLIKLSQYSNIPICNLRLDSMDYIIDVLYARKLKKENIVLWWNEKAPLPDHGGIQNDFDLNTSWIMNDSEFPKINNSGVYDNVVLDVGVDNLTVNTILTSALINDAEGSDLVNNNMGIDDKDAVINSPSEFVHDAFSNDALNVLRGMLKEWWDEALKENSTADLLVNSLASWVQNPNAKLFDGLLRYHVHNLTKKALLQLVNEFSALGSTIVYADRNQILIKTNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLLIWMDKFNFSGLACIEIEEKENQDYTAVSQWQLKKFLSPIYQPEFEDWMMIILDSMLKTKQSYLKLNSGTQRPTQIVNVKKQDKEDSVENSLNGFSHLFSKPLMKRVKKLFKNQQEFILDPQYEADYVIPVLPGSHLNVKNPLLELVKSLCHVMLLSKSTILEIRTLRKELLKIFELREFAKVAEFKDPSLSLVVPDFLCEYCFFISDIDFCKAAPESIFSCVRCHKAFNQVLLQEHLIQKLRSDIESYLIQDLRCSRCHKVKRDYMSAHCPCAGAWEGTLPRESIVQKLNVFKQVAKYYGFDILLSCIADLTI

Source Source

Source organism organism	Saccharomyces cerevisiae
Common name common_name	;baker's yeast ;
NCBI taxonomy ID ncbi_taxonomy_id	4932
Host organism host_organism	Saccharomyces cerevisiae

Entity 16 Entity 16 non-polymer

Description description	ADENOSINE-5'-TRIPHOSPHATE
Molecular weight formula_weight	507.2 kDa
Source method src_method	syn
Copy count entity_count	8

Entity 17 Entity 17 non-polymer

Description description	ZINC ION
Molecular weight formula_weight	65.4 kDa
Source method src_method	syn
Copy count entity_count	14

Entity 18 Entity 18 non-polymer

Description description	MAGNESIUM ION
Molecular weight formula_weight	24.3 kDa
Source method src_method	syn
Copy count entity_count	6

Entity 19 Entity 19 non-polymer

Description description	ADENOSINE-5'-DIPHOSPHATE
Molecular weight formula_weight	427.2 kDa
Source method src_method	syn
Copy count entity_count	4

▶

Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	3.40 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	71348

S. cerevisiae CMGE dimer nucleating origin DNA melting

1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA replication licensing factor MCM2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA replication licensing factor MCM3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA replication licensing factor MCM4

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA helicase

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA replication licensing factor MCM6

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA replication licensing factor MCM7

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA replication complex GINS protein PSF3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA replication complex GINS protein SLD5

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Cell division control protein 45

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA polymerase epsilon subunit B

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer