8ony

Human Methionine Aminopeptidase 2 at the 80S ribosome

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

60S ribosomal protein L38

OrganismNot specified

UniProt P63173

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 28S rRNA × 1 60S ribosomal protein L26 × 1 (P61254) 60S ribosomal protein L35 × 1 (P42766) 60S ribosomal protein L23a × 1 (P62750) 60S ribosomal protein L19 × 1 (P84098) 5.8S rRNA × 1 Methionine aminopeptidase 2 × 1 (P50579) COBALT (II) ION × 2 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL38_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain Lk; PDBConstruct 1–70; UniProt 1–70

60S ribosomal protein L26

OrganismNot specified

UniProt P61254

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 28S rRNA × 1 60S ribosomal protein L38 × 1 (P63173) 60S ribosomal protein L35 × 1 (P42766) 60S ribosomal protein L23a × 1 (P62750) 60S ribosomal protein L19 × 1 (P84098) 5.8S rRNA × 1 Methionine aminopeptidase 2 × 1 (P50579) COBALT (II) ION × 2 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL26_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain LY; PDBConstruct 1–145; UniProt 1–145

60S ribosomal protein L35

OrganismNot specified

UniProt P42766

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 28S rRNA × 1 60S ribosomal protein L38 × 1 (P63173) 60S ribosomal protein L26 × 1 (P61254) 60S ribosomal protein L23a × 1 (P62750) 60S ribosomal protein L19 × 1 (P84098) 5.8S rRNA × 1 Methionine aminopeptidase 2 × 1 (P50579) COBALT (II) ION × 2 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL35_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain Lh; PDBConstruct 1–123; UniProt 1–123

60S ribosomal protein L23a

OrganismNot specified

UniProt P62750

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 28S rRNA × 1 60S ribosomal protein L38 × 1 (P63173) 60S ribosomal protein L26 × 1 (P61254) 60S ribosomal protein L35 × 1 (P42766) 60S ribosomal protein L19 × 1 (P84098) 5.8S rRNA × 1 Methionine aminopeptidase 2 × 1 (P50579) COBALT (II) ION × 2 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL23A_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain LX; PDBConstruct 1–156; UniProt 1–156

60S ribosomal protein L19

OrganismNot specified

UniProt P84098

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 28S rRNA × 1 60S ribosomal protein L38 × 1 (P63173) 60S ribosomal protein L26 × 1 (P61254) 60S ribosomal protein L35 × 1 (P42766) 60S ribosomal protein L23a × 1 (P62750) 5.8S rRNA × 1 Methionine aminopeptidase 2 × 1 (P50579) COBALT (II) ION × 2 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL19_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain LR; PDBConstruct 1–196; UniProt 1–196

Methionine aminopeptidase 2

Homo sapiens

UniProt P50579

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 28S rRNA × 1 60S ribosomal protein L38 × 1 (P63173) 60S ribosomal protein L26 × 1 (P61254) 60S ribosomal protein L35 × 1 (P42766) 60S ribosomal protein L23a × 1 (P62750) 60S ribosomal protein L19 × 1 (P84098) 5.8S rRNA × 1 COBALT (II) ION × 2 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name MAP2_HUMAN
Isoform —
PDB entities 8
Chains and sequence ranges Author chain A; PDBConstruct 1–478; UniProt 1–478

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8ony
Deposition date deposition_date2023-04-04
Last revision last_revision2024-02-21
Structure title titleHuman Methionine Aminopeptidase 2 at the 80S ribosome
Keywords keywords;Ribosome Associated Factor, Protease, Tunnel exit, Protein Maturation, Proteostasis, NME, p67, MAP, MetAP, MAP2, MetAP2, ES27L, PTE, METAL BINDING PROTEIN ;; METAL BINDING PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8ony__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8ony__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8ony__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)47.43 Å
Rg (electron density)49.15 Å
Total Rg49.08 Å
Atom count12382
Residues1174
Excluded volume204860 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8ony__assembly_1__model_1 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (9)

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7. Citations (1)