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9pvy

Cryo-EM structure of cardiac amyloid fibril from a variant apolipoprotein A-I L90P amyloidosis patient

Method: ELECTRON MICROSCOPY Dmax: 90.8 Å Quality: GOOD

SAXS Profile

SAXS profile for 9pvy

P(r) Distribution

P(r) distribution for 9pvy

1. Structure Basics

entry_id9pvy
deposition_date2025-08-04
titleCryo-EM structure of cardiac amyloid fibril from a variant apolipoprotein A-I L90P amyloidosis patient
keywordsApolipoprotein A-I, AApoAI, L90P, Amyloidosis., PROTEIN FIBRIL; PROTEIN FIBRIL
methodELECTRON MICROSCOPY

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier27.63
rg_electron27.16
i071194400.00
molecular_weight67896.0 kDa
excluded_volume85468 ų
envelope_volume97305 ų
shell_volume30283 ų
envelope_diameter95.5
shell_rg34.42
envelope_rg27.62
shape_rg27.22
total_rg27.68
total_atoms4810
n_residues600
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax90.8
rg_real27.66
rg_real_error0.67
i0_real7.1190e+07
i0_real_error1.1690e+06
rg_reciprocal27.65
i0_reciprocal71190000.0000
total_estimate0.8869
solution_quality GOOD a GOOD solution
n_peaks1
r_peak_primary89.2
skewness0.344
kurtosis-0.425
angular_range— – 0.2850 −1
current_alpha0.0000
highest_alpha20020000.0000
n_real_points58
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.890; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.971; Smooth: 0.886

4. Crystallography & Experiment

5. Entities & Polymer Info (1)

6. Citations (1)

7. Files & Curves (10)