9pvz
Cryo-EM structure of cardiac amyloid fibril from a variant apolipoprotein A-I R173P amyloidosis patient
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 9pvz |
| deposition_date | 2025-08-04 |
| title | Cryo-EM structure of cardiac amyloid fibril from a variant apolipoprotein A-I R173P amyloidosis patient |
| keywords | Apolipoprotein A-I, AApoAI, R173P, cardiac, amyloidosis., PROTEIN FIBRIL; PROTEIN FIBRIL |
| method | ELECTRON MICROSCOPY |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 27.57 Å |
| rg_electron | 27.09 Å |
| i0 | 71320200.00 |
| molecular_weight | 67896.0 kDa |
| excluded_volume | 85468 ų |
| envelope_volume | 97118 ų |
| shell_volume | 30256 ų |
| envelope_diameter | 95.7 Å |
| shell_rg | 34.41 Å |
| envelope_rg | 27.59 Å |
| shape_rg | 27.14 Å |
| total_rg | 27.62 Å |
| total_atoms | 4810 |
| n_residues | 600 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 91.6 Å |
| rg_real | 27.60 Å |
| rg_real_error | 0.65 Å |
| i0_real | 7.1320e+07 |
| i0_real_error | 1.0940e+06 |
| rg_reciprocal | 27.59 Å |
| i0_reciprocal | 71320000.0000 |
| total_estimate | 0.6859 |
| solution_quality | REASONABLE a REASONABLE solution |
| n_peaks | 2 |
| r_peak_primary | 28.4 Å |
| skewness | 0.343 |
| kurtosis | -0.428 |
| angular_range | — – 0.2900 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 19630000.0000 |
| n_real_points | 59 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.876; Stabil: 1.000; Sysdev: 0.127; Positv: 1.000; Valcen: 0.975; Smooth: 0.930 |