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9v44

Coupling of polymerase-nucleoprotein-RNA in an influenza virus mini ribonucleoprotein complex

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Polymerase acidic protein

Influenza A virus (A/Victoria/3/1975(H3N2))

UniProt H9XIJ2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 4 RNA 2 RNA-directed RNA polymerase catalytic subunit × 1 （H9XIJ3） Polymerase basic protein 2 × 1 （P31345） Nucleoprotein × 1 （Q9WLG4） ;RNA (5'-R(P*UP*UP*UP*GP*UP*CP*AP*CP*CP*CP*UP*GP*CP*U)-3') ; × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*UP*GP*UP*UP*UP*UP*UP*UP*AP*U)-3') ; × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
9v44 9v46

2 assemblies

View Construct and Data Evidence
UniProt name H9XIJ2_I75A3
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–716； UniProt 1–716

RNA-directed RNA polymerase catalytic subunit

Influenza A virus (A/Victoria/3/1975(H3N2))

UniProt H9XIJ3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 4 RNA 2 Polymerase acidic protein × 1 （H9XIJ2） Polymerase basic protein 2 × 1 （P31345） Nucleoprotein × 1 （Q9WLG4） ;RNA (5'-R(P*UP*UP*UP*GP*UP*CP*AP*CP*CP*CP*UP*GP*CP*U)-3') ; × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*UP*GP*UP*UP*UP*UP*UP*UP*AP*U)-3') ; × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
9v44 9v46

2 assemblies

View Construct and Data Evidence
UniProt name H9XIJ3_I75A3
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–757； UniProt 1–757

Polymerase basic protein 2

Influenza A virus (A/Victoria/3/1975(H3N2))

UniProt P31345

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 4 RNA 2 Polymerase acidic protein × 1 （H9XIJ2） RNA-directed RNA polymerase catalytic subunit × 1 （H9XIJ3） Nucleoprotein × 1 （Q9WLG4） ;RNA (5'-R(P*UP*UP*UP*GP*UP*CP*AP*CP*CP*CP*UP*GP*CP*U)-3') ; × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*UP*GP*UP*UP*UP*UP*UP*UP*AP*U)-3') ; × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
2gmo 2vy6 2vy7 2vy8 4nce 4ncm 4p1u 6euv 6euv 6euv 6euv 6euy

18 assemblies; showing the first 12

Homodimer

None

Homotetramer

None

Other homooligomers
2vqz

1 assemblies

Heteromeric or nucleic-acid complex
2jdq 2jdq 4uad 4uae 4uaf 9v44 9v46

7 assemblies

View Construct and Data Evidence
UniProt name PB2_I75A3
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 1–759； UniProt 1–759

Nucleoprotein

Influenza A virus (A/Victoria/3/1975(H3N2))

UniProt Q9WLG4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 4 RNA 2 Polymerase acidic protein × 1 （H9XIJ2） RNA-directed RNA polymerase catalytic subunit × 1 （H9XIJ3） Polymerase basic protein 2 × 1 （P31345） ;RNA (5'-R(P*UP*UP*UP*GP*UP*CP*AP*CP*CP*CP*UP*GP*CP*U)-3') ; × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*UP*GP*UP*UP*UP*UP*UP*UP*AP*U)-3') ; × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
9v44 9v47 9v48

3 assemblies

View Construct and Data Evidence
UniProt name Q9WLG4_I75A3
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D； PDBConstruct 1–498； UniProt 1–498

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9v44
Deposition date deposition_date2025-05-22
Structure title titleCoupling of polymerase-nucleoprotein-RNA in an influenza virus mini ribonucleoprotein complex
Keywords keywordsInfluenza virus, ribonucleoprotein complex, polymerase, cryo-EM, VIRAL PROTEIN/RNA, VIRAL PROTEIN-RNA complex; VIRAL PROTEIN/RNA
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9v44__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9v44__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9v44__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）46.34 Å
Rg (electron density)46.61 Å
Total Rg46.61 Å
Atom count17835
Residues2160
Excluded volume314530 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9v44__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)