9y9z

Cryo-EM structure of conoid fiber from Toxoplasma gondii (24-nm repeat)

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

CF2, TGME49_258090

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	S8GBZ2_TOXGM
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain 1； PDBConstruct 1–954； UniProt 1–954 Author chain 2； PDBConstruct 1–954； UniProt 1–954 Author chain A； PDBConstruct 1–954； UniProt 1–954 Author chain B； PDBConstruct 1–954； UniProt 1–954 Author chain C； PDBConstruct 1–954； UniProt 1–954 Author chain D； PDBConstruct 1–954； UniProt 1–954 Author chain E； PDBConstruct 1–954； UniProt 1–954 Author chain F； PDBConstruct 1–954； UniProt 1–954 Author chain G； PDBConstruct 1–954； UniProt 1–954 Author chain H； PDBConstruct 1–954； UniProt 1–954 Author chain I； PDBConstruct 1–954； UniProt 1–954 Author chain J； PDBConstruct 1–954； UniProt 1–954 Author chain K； PDBConstruct 1–954； UniProt 1–954 Author chain L； PDBConstruct 1–954； UniProt 1–954 Author chain M； PDBConstruct 1–954； UniProt 1–954 Author chain N； PDBConstruct 1–954； UniProt 1–954 Author chain O； PDBConstruct 1–954； UniProt 1–954 Author chain P； PDBConstruct 1–954； UniProt 1–954 Author chain Q； PDBConstruct 1–954； UniProt 1–954 Author chain R； PDBConstruct 1–954； UniProt 1–954 Author chain S； PDBConstruct 1–954； UniProt 1–954 Author chain T； PDBConstruct 1–954； UniProt 1–954 Author chain U； PDBConstruct 1–954； UniProt 1–954 Author chain V； PDBConstruct 1–954； UniProt 1–954 Author chain W； PDBConstruct 1–954； UniProt 1–954 Author chain X； PDBConstruct 1–954； UniProt 1–954 Author chain Y； PDBConstruct 1–954； UniProt 1–954 Author chain Z； PDBConstruct 1–954； UniProt 1–954 Author chain a； PDBConstruct 1–954； UniProt 1–954 Author chain b； PDBConstruct 1–954； UniProt 1–954 Author chain c； PDBConstruct 1–954； UniProt 1–954 Author chain d； PDBConstruct 1–954； UniProt 1–954 Author chain e； PDBConstruct 1–954； UniProt 1–954 Author chain f； PDBConstruct 1–954； UniProt 1–954 Author chain g； PDBConstruct 1–954； UniProt 1–954 Author chain h； PDBConstruct 1–954； UniProt 1–954 Author chain i； PDBConstruct 1–954； UniProt 1–954 Author chain j； PDBConstruct 1–954； UniProt 1–954 Author chain k； PDBConstruct 1–954； UniProt 1–954 Author chain l； PDBConstruct 1–954； UniProt 1–954 Author chain m； PDBConstruct 1–954； UniProt 1–954 Author chain n； PDBConstruct 1–954； UniProt 1–954 Author chain o； PDBConstruct 1–954； UniProt 1–954 Author chain p； PDBConstruct 1–954； UniProt 1–954 Author chain q； PDBConstruct 1–954； UniProt 1–954 Author chain r； PDBConstruct 1–954； UniProt 1–954 Author chain s； PDBConstruct 1–954； UniProt 1–954 Author chain t； PDBConstruct 1–954； UniProt 1–954 Author chain u； PDBConstruct 1–954； UniProt 1–954 Author chain v； PDBConstruct 1–954； UniProt 1–954 Author chain w； PDBConstruct 1–954； UniProt 1–954 Author chain x； PDBConstruct 1–954； UniProt 1–954 Author chain y； PDBConstruct 1–954； UniProt 1–954 Author chain z； PDBConstruct 1–954； UniProt 1–954

CF1, TGME49_222350

OrganismNot specified

UniProt S8GJP0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	S8GJP0_TOXGM
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain 10； PDBConstruct 1–410； UniProt 1–410 Author chain 11； PDBConstruct 1–410； UniProt 1–410 Author chain 12； PDBConstruct 1–410； UniProt 1–410 Author chain 13； PDBConstruct 1–410； UniProt 1–410 Author chain 14； PDBConstruct 1–410； UniProt 1–410 Author chain 15； PDBConstruct 1–410； UniProt 1–410 Author chain 16； PDBConstruct 1–410； UniProt 1–410 Author chain 3； PDBConstruct 1–410； UniProt 1–410 Author chain 4； PDBConstruct 1–410； UniProt 1–410 Author chain 5； PDBConstruct 1–410； UniProt 1–410 Author chain 6； PDBConstruct 1–410； UniProt 1–410 Author chain 7； PDBConstruct 1–410； UniProt 1–410 Author chain 8； PDBConstruct 1–410； UniProt 1–410 Author chain 9； PDBConstruct 1–410； UniProt 1–410

Tubulin alpha chain

OrganismNot specified

UniProt P10873

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TBA_TOXGO
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain 1A； PDBConstruct 1–453； UniProt 1–453 Author chain 1C； PDBConstruct 1–453； UniProt 1–453 Author chain 1E； PDBConstruct 1–453； UniProt 1–453 Author chain 1G； PDBConstruct 1–453； UniProt 1–453 Author chain 1I； PDBConstruct 1–453； UniProt 1–453 Author chain 1K； PDBConstruct 1–453； UniProt 1–453 Author chain 1M； PDBConstruct 1–453； UniProt 1–453 Author chain 2A； PDBConstruct 1–453； UniProt 1–453 Author chain 2C； PDBConstruct 1–453； UniProt 1–453 Author chain 2E； PDBConstruct 1–453； UniProt 1–453 Author chain 2G； PDBConstruct 1–453； UniProt 1–453 Author chain 2I； PDBConstruct 1–453； UniProt 1–453 Author chain 2K； PDBConstruct 1–453； UniProt 1–453 Author chain 2M； PDBConstruct 1–453； UniProt 1–453 Author chain 3A； PDBConstruct 1–453； UniProt 1–453 Author chain 3C； PDBConstruct 1–453； UniProt 1–453 Author chain 3E； PDBConstruct 1–453； UniProt 1–453 Author chain 3G； PDBConstruct 1–453； UniProt 1–453 Author chain 3I； PDBConstruct 1–453； UniProt 1–453 Author chain 3K； PDBConstruct 1–453； UniProt 1–453 Author chain 3M； PDBConstruct 1–453； UniProt 1–453 Author chain 4A； PDBConstruct 1–453； UniProt 1–453 Author chain 4C； PDBConstruct 1–453； UniProt 1–453 Author chain 4E； PDBConstruct 1–453； UniProt 1–453 Author chain 4G； PDBConstruct 1–453； UniProt 1–453 Author chain 4I； PDBConstruct 1–453； UniProt 1–453 Author chain 4K； PDBConstruct 1–453； UniProt 1–453 Author chain 4M； PDBConstruct 1–453； UniProt 1–453 Author chain 5A； PDBConstruct 1–453； UniProt 1–453 Author chain 5C； PDBConstruct 1–453； UniProt 1–453 Author chain 5E； PDBConstruct 1–453； UniProt 1–453 Author chain 5G； PDBConstruct 1–453； UniProt 1–453 Author chain 5I； PDBConstruct 1–453； UniProt 1–453 Author chain 5K； PDBConstruct 1–453； UniProt 1–453 Author chain 5M； PDBConstruct 1–453； UniProt 1–453 Author chain 6A； PDBConstruct 1–453； UniProt 1–453 Author chain 6C； PDBConstruct 1–453； UniProt 1–453 Author chain 6E； PDBConstruct 1–453； UniProt 1–453 Author chain 6G； PDBConstruct 1–453； UniProt 1–453 Author chain 6I； PDBConstruct 1–453； UniProt 1–453 Author chain 6K； PDBConstruct 1–453； UniProt 1–453 Author chain 6M； PDBConstruct 1–453； UniProt 1–453 Author chain 7A； PDBConstruct 1–453； UniProt 1–453 Author chain 7C； PDBConstruct 1–453； UniProt 1–453 Author chain 7E； PDBConstruct 1–453； UniProt 1–453 Author chain 7G； PDBConstruct 1–453； UniProt 1–453 Author chain 7I； PDBConstruct 1–453； UniProt 1–453 Author chain 7K； PDBConstruct 1–453； UniProt 1–453 Author chain 7M； PDBConstruct 1–453； UniProt 1–453 Author chain 8A； PDBConstruct 1–453； UniProt 1–453 Author chain 8C； PDBConstruct 1–453； UniProt 1–453 Author chain 8E； PDBConstruct 1–453； UniProt 1–453 Author chain 8G； PDBConstruct 1–453； UniProt 1–453 Author chain 8I； PDBConstruct 1–453； UniProt 1–453 Author chain 8K； PDBConstruct 1–453； UniProt 1–453 Author chain 8M； PDBConstruct 1–453； UniProt 1–453 Author chain 9A； PDBConstruct 1–453； UniProt 1–453 Author chain 9C； PDBConstruct 1–453； UniProt 1–453 Author chain 9E； PDBConstruct 1–453； UniProt 1–453 Author chain 9G； PDBConstruct 1–453； UniProt 1–453 Author chain 9I； PDBConstruct 1–453； UniProt 1–453 Author chain 9K； PDBConstruct 1–453； UniProt 1–453 Author chain 9M； PDBConstruct 1–453； UniProt 1–453

Tubulin beta chain

OrganismNot specified

UniProt I7BFC9

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	I7BFC9_TOXGO
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain 1B； PDBConstruct 1–449； UniProt 1–449 Author chain 1D； PDBConstruct 1–449； UniProt 1–449 Author chain 1F； PDBConstruct 1–449； UniProt 1–449 Author chain 1H； PDBConstruct 1–449； UniProt 1–449 Author chain 1J； PDBConstruct 1–449； UniProt 1–449 Author chain 1L； PDBConstruct 1–449； UniProt 1–449 Author chain 1N； PDBConstruct 1–449； UniProt 1–449 Author chain 2B； PDBConstruct 1–449； UniProt 1–449 Author chain 2D； PDBConstruct 1–449； UniProt 1–449 Author chain 2F； PDBConstruct 1–449； UniProt 1–449 Author chain 2H； PDBConstruct 1–449； UniProt 1–449 Author chain 2J； PDBConstruct 1–449； UniProt 1–449 Author chain 2L； PDBConstruct 1–449； UniProt 1–449 Author chain 3B； PDBConstruct 1–449； UniProt 1–449 Author chain 3D； PDBConstruct 1–449； UniProt 1–449 Author chain 3F； PDBConstruct 1–449； UniProt 1–449 Author chain 3H； PDBConstruct 1–449； UniProt 1–449 Author chain 3J； PDBConstruct 1–449； UniProt 1–449 Author chain 3L； PDBConstruct 1–449； UniProt 1–449 Author chain 4B； PDBConstruct 1–449； UniProt 1–449 Author chain 4D； PDBConstruct 1–449； UniProt 1–449 Author chain 4F； PDBConstruct 1–449； UniProt 1–449 Author chain 4H； PDBConstruct 1–449； UniProt 1–449 Author chain 4J； PDBConstruct 1–449； UniProt 1–449 Author chain 4L； PDBConstruct 1–449； UniProt 1–449 Author chain 5B； PDBConstruct 1–449； UniProt 1–449 Author chain 5D； PDBConstruct 1–449； UniProt 1–449 Author chain 5F； PDBConstruct 1–449； UniProt 1–449 Author chain 5H； PDBConstruct 1–449； UniProt 1–449 Author chain 5J； PDBConstruct 1–449； UniProt 1–449 Author chain 5L； PDBConstruct 1–449； UniProt 1–449 Author chain 5N； PDBConstruct 1–449； UniProt 1–449 Author chain 6B； PDBConstruct 1–449； UniProt 1–449 Author chain 6D； PDBConstruct 1–449； UniProt 1–449 Author chain 6F； PDBConstruct 1–449； UniProt 1–449 Author chain 6H； PDBConstruct 1–449； UniProt 1–449 Author chain 6J； PDBConstruct 1–449； UniProt 1–449 Author chain 6L； PDBConstruct 1–449； UniProt 1–449 Author chain 6N； PDBConstruct 1–449； UniProt 1–449 Author chain 7B； PDBConstruct 1–449； UniProt 1–449 Author chain 7D； PDBConstruct 1–449； UniProt 1–449 Author chain 7F； PDBConstruct 1–449； UniProt 1–449 Author chain 7H； PDBConstruct 1–449； UniProt 1–449 Author chain 7J； PDBConstruct 1–449； UniProt 1–449 Author chain 7L； PDBConstruct 1–449； UniProt 1–449 Author chain 8B； PDBConstruct 1–449； UniProt 1–449 Author chain 8D； PDBConstruct 1–449； UniProt 1–449 Author chain 8F； PDBConstruct 1–449； UniProt 1–449 Author chain 8H； PDBConstruct 1–449； UniProt 1–449 Author chain 8J； PDBConstruct 1–449； UniProt 1–449 Author chain 8L； PDBConstruct 1–449； UniProt 1–449 Author chain 9B； PDBConstruct 1–449； UniProt 1–449 Author chain 9D； PDBConstruct 1–449； UniProt 1–449 Author chain 9F； PDBConstruct 1–449； UniProt 1–449 Author chain 9H； PDBConstruct 1–449； UniProt 1–449 Author chain 9J； PDBConstruct 1–449； UniProt 1–449 Author chain 9L； PDBConstruct 1–449； UniProt 1–449

Spindle assembly abnormal protein 6 N-terminal domain-containing protein

OrganismNot specified

UniProt A0A7J6KDX1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A7J6KDX1_TOXGO
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain 20； PDBConstruct 1–263； UniProt 1–263 Author chain 21； PDBConstruct 1–263； UniProt 1–263 Author chain 22； PDBConstruct 1–263； UniProt 1–263 Author chain 23； PDBConstruct 1–263； UniProt 1–263 Author chain 24； PDBConstruct 1–263； UniProt 1–263 Author chain 25； PDBConstruct 1–263； UniProt 1–263 Author chain 26； PDBConstruct 1–263； UniProt 1–263 Author chain 27； PDBConstruct 1–263； UniProt 1–263 Author chain 28； PDBConstruct 1–263； UniProt 1–263 Author chain 29； PDBConstruct 1–263； UniProt 1–263 Author chain 30； PDBConstruct 1–263； UniProt 1–263 Author chain 31； PDBConstruct 1–263； UniProt 1–263 Author chain 32； PDBConstruct 1–263； UniProt 1–263 Author chain 33； PDBConstruct 1–263； UniProt 1–263 Author chain 35； PDBConstruct 1–263； UniProt 1–263 Author chain 36； PDBConstruct 1–263； UniProt 1–263 Author chain 37； PDBConstruct 1–263； UniProt 1–263 Author chain 38； PDBConstruct 1–263； UniProt 1–263 Author chain 39； PDBConstruct 1–263； UniProt 1–263 Author chain 40； PDBConstruct 1–263； UniProt 1–263 Author chain 42； PDBConstruct 1–263； UniProt 1–263 Author chain 43； PDBConstruct 1–263； UniProt 1–263 Author chain 44； PDBConstruct 1–263； UniProt 1–263 Author chain 45； PDBConstruct 1–263； UniProt 1–263 Author chain 46； PDBConstruct 1–263； UniProt 1–263 Author chain 47； PDBConstruct 1–263； UniProt 1–263 Author chain 48； PDBConstruct 1–263； UniProt 1–263 Author chain 49； PDBConstruct 1–263； UniProt 1–263 Author chain 50； PDBConstruct 1–263； UniProt 1–263 Author chain 51； PDBConstruct 1–263； UniProt 1–263 Author chain 52； PDBConstruct 1–263； UniProt 1–263 Author chain 53； PDBConstruct 1–263； UniProt 1–263 Author chain 54； PDBConstruct 1–263； UniProt 1–263 Author chain 55； PDBConstruct 1–263； UniProt 1–263 Author chain 56； PDBConstruct 1–263； UniProt 1–263 Author chain 57； PDBConstruct 1–263； UniProt 1–263 Author chain 58； PDBConstruct 1–263； UniProt 1–263 Author chain 59； PDBConstruct 1–263； UniProt 1–263 Author chain 60； PDBConstruct 1–263； UniProt 1–263 Author chain 61； PDBConstruct 1–263； UniProt 1–263 Author chain 62； PDBConstruct 1–263； UniProt 1–263

CIP3, TGME49_225020

OrganismNot specified

UniProt S8G5Q1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	S8G5Q1_TOXGM
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain 63； PDBConstruct 1–1010； UniProt 1–1010 Author chain 64； PDBConstruct 1–1010； UniProt 1–1010 Author chain 65； PDBConstruct 1–1010； UniProt 1–1010 Author chain 66； PDBConstruct 1–1010； UniProt 1–1010 Author chain 67； PDBConstruct 1–1010； UniProt 1–1010 Author chain 68； PDBConstruct 1–1010； UniProt 1–1010 Author chain 69； PDBConstruct 1–1010； UniProt 1–1010

CF6, TGME49_245640

OrganismNot specified

UniProt A0A086KRX4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A086KRX4_TOXGO
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain 71； PDBConstruct 1–416； UniProt 1–416 Author chain 72； PDBConstruct 1–416； UniProt 1–416 Author chain 73； PDBConstruct 1–416； UniProt 1–416 Author chain 75； PDBConstruct 1–416； UniProt 1–416 Author chain 76； PDBConstruct 1–416； UniProt 1–416 Author chain 77； PDBConstruct 1–416； UniProt 1–416 Author chain 78； PDBConstruct 1–416； UniProt 1–416 Author chain 79； PDBConstruct 1–416； UniProt 1–416 Author chain 80； PDBConstruct 1–416； UniProt 1–416 Author chain 82； PDBConstruct 1–416； UniProt 1–416 Author chain 83； PDBConstruct 1–416； UniProt 1–416 Author chain 84； PDBConstruct 1–416； UniProt 1–416 Author chain 85； PDBConstruct 1–416； UniProt 1–416 Author chain 86； PDBConstruct 1–416； UniProt 1–416 Author chain 87； PDBConstruct 1–416； UniProt 1–416 Author chain 89； PDBConstruct 1–416； UniProt 1–416 Author chain 90； PDBConstruct 1–416； UniProt 1–416 Author chain 91； PDBConstruct 1–416； UniProt 1–416 Author chain 92； PDBConstruct 1–416； UniProt 1–416 Author chain 93； PDBConstruct 1–416； UniProt 1–416 Author chain 94； PDBConstruct 1–416； UniProt 1–416 Author chain 95； PDBConstruct 1–416； UniProt 1–416 Author chain 96； PDBConstruct 1–416； UniProt 1–416 Author chain 97； PDBConstruct 1–416； UniProt 1–416

CF4, TGME49_246720

OrganismNot specified

UniProt A0A086KR31

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A086KR31_TOXGO
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain A1； PDBConstruct 1–502； UniProt 1–502 Author chain A2； PDBConstruct 1–502； UniProt 1–502 Author chain A3； PDBConstruct 1–502； UniProt 1–502 Author chain A4； PDBConstruct 1–502； UniProt 1–502 Author chain A5； PDBConstruct 1–502； UniProt 1–502 Author chain A6； PDBConstruct 1–502； UniProt 1–502 Author chain A7； PDBConstruct 1–502； UniProt 1–502 Author chain A8； PDBConstruct 1–502； UniProt 1–502 Author chain A9； PDBConstruct 1–502； UniProt 1–502

CF3, TGME49_255895

OrganismNot specified

UniProt S8F3E8

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	S8F3E8_TOXGM
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain B1； PDBConstruct 1–556； UniProt 1–556 Author chain B2； PDBConstruct 1–556； UniProt 1–556 Author chain B3； PDBConstruct 1–556； UniProt 1–556 Author chain B4； PDBConstruct 1–556； UniProt 1–556 Author chain B5； PDBConstruct 1–556； UniProt 1–556 Author chain B6； PDBConstruct 1–556； UniProt 1–556 Author chain B7； PDBConstruct 1–556； UniProt 1–556

CPH1, TGME49_266630

OrganismNot specified

UniProt A0A7J6KB56

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A7J6KB56_TOXGO
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain C0； PDBConstruct 1–582； UniProt 1–582 Author chain C6； PDBConstruct 1–582； UniProt 1–582 Author chain C7； PDBConstruct 1–582； UniProt 1–582 Author chain C8； PDBConstruct 1–582； UniProt 1–582 Author chain C9； PDBConstruct 1–582； UniProt 1–582 Author chain D0； PDBConstruct 1–582； UniProt 1–582 Author chain D1； PDBConstruct 1–582； UniProt 1–582 Author chain D2； PDBConstruct 1–582； UniProt 1–582 Author chain D3； PDBConstruct 1–582； UniProt 1–582 Author chain D4； PDBConstruct 1–582； UniProt 1–582 Author chain D5； PDBConstruct 1–582； UniProt 1–582 Author chain D6； PDBConstruct 1–582； UniProt 1–582 Author chain D7； PDBConstruct 1–582； UniProt 1–582 Author chain D8； PDBConstruct 1–582； UniProt 1–582 Author chain D9； PDBConstruct 1–582； UniProt 1–582 Author chain E0； PDBConstruct 1–582； UniProt 1–582 Author chain E1； PDBConstruct 1–582； UniProt 1–582 Author chain E2； PDBConstruct 1–582； UniProt 1–582 Author chain E3； PDBConstruct 1–582； UniProt 1–582 Author chain E4； PDBConstruct 1–582； UniProt 1–582 Author chain E5； PDBConstruct 1–582； UniProt 1–582 Author chain E6； PDBConstruct 1–582； UniProt 1–582 Author chain E7； PDBConstruct 1–582； UniProt 1–582 Author chain E8； PDBConstruct 1–582； UniProt 1–582 Author chain E9； PDBConstruct 1–582； UniProt 1–582 Author chain F1； PDBConstruct 1–582； UniProt 1–582 Author chain F2； PDBConstruct 1–582； UniProt 1–582 Author chain F3； PDBConstruct 1–582； UniProt 1–582

Microtubule associated protein SPM1

OrganismNot specified

UniProt A0A7J6K285

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A7J6K285_TOXGO
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain C1； PDBConstruct 1–351； UniProt 1–351 Author chain C2； PDBConstruct 1–351； UniProt 1–351 Author chain C3； PDBConstruct 1–351； UniProt 1–351 Author chain C4； PDBConstruct 1–351； UniProt 1–351 Author chain C5； PDBConstruct 1–351； UniProt 1–351

PRP, TGME49_291880

OrganismNot specified

UniProt A0A151HK62

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） CF5, TGME49_297180 × 7 （S8FEB8） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A151HK62_TOXGO
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain F0； PDBConstruct 1–783； UniProt 1–783 Author chain F5； PDBConstruct 1–783； UniProt 1–783 Author chain F6； PDBConstruct 1–783； UniProt 1–783 Author chain F7； PDBConstruct 1–783； UniProt 1–783 Author chain F8； PDBConstruct 1–783； UniProt 1–783 Author chain F9； PDBConstruct 1–783； UniProt 1–783 Author chain G0； PDBConstruct 1–783； UniProt 1–783 Author chain G1； PDBConstruct 1–783； UniProt 1–783 Author chain G2； PDBConstruct 1–783； UniProt 1–783 Author chain G3； PDBConstruct 1–783； UniProt 1–783 Author chain G4； PDBConstruct 1–783； UniProt 1–783 Author chain G5； PDBConstruct 1–783； UniProt 1–783 Author chain G6； PDBConstruct 1–783； UniProt 1–783 Author chain G7； PDBConstruct 1–783； UniProt 1–783 Author chain G8； PDBConstruct 1–783； UniProt 1–783 Author chain G9； PDBConstruct 1–783； UniProt 1–783 Author chain H0； PDBConstruct 1–783； UniProt 1–783 Author chain H1； PDBConstruct 1–783； UniProt 1–783 Author chain H2； PDBConstruct 1–783； UniProt 1–783 Author chain H3； PDBConstruct 1–783； UniProt 1–783 Author chain H4； PDBConstruct 1–783； UniProt 1–783 Author chain H5； PDBConstruct 1–783； UniProt 1–783 Author chain H6； PDBConstruct 1–783； UniProt 1–783 Author chain H7； PDBConstruct 1–783； UniProt 1–783 Author chain H8； PDBConstruct 1–783； UniProt 1–783 Author chain H9； PDBConstruct 1–783； UniProt 1–783 Author chain I1； PDBConstruct 1–783； UniProt 1–783 Author chain I2； PDBConstruct 1–783； UniProt 1–783 Author chain I3； PDBConstruct 1–783； UniProt 1–783 Author chain I4； PDBConstruct 1–783； UniProt 1–783 Author chain I5； PDBConstruct 1–783； UniProt 1–783 Author chain I6； PDBConstruct 1–783； UniProt 1–783 Author chain I7； PDBConstruct 1–783； UniProt 1–783 Author chain I8； PDBConstruct 1–783； UniProt 1–783 Author chain I9； PDBConstruct 1–783； UniProt 1–783

CF5, TGME49_297180

OrganismNot specified

UniProt S8FEB8

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） DCX, TGME49_256030 × 27 （B6KAS6） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	S8FEB8_TOXGM
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain J1； PDBConstruct 1–871； UniProt 1–871 Author chain J2； PDBConstruct 1–871； UniProt 1–871 Author chain J3； PDBConstruct 1–871； UniProt 1–871 Author chain J4； PDBConstruct 1–871； UniProt 1–871 Author chain J5； PDBConstruct 1–871； UniProt 1–871 Author chain J6； PDBConstruct 1–871； UniProt 1–871 Author chain J7； PDBConstruct 1–871； UniProt 1–871

DCX, TGME49_256030

OrganismNot specified

UniProt B6KAS6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 378	CF2, TGME49_258090 × 54 （S8GBZ2） CF1, TGME49_222350 × 14 （S8GJP0） Tubulin alpha chain × 63 （P10873） Tubulin beta chain × 57 （I7BFC9） Spindle assembly abnormal protein 6 N-terminal domain-containing protein × 41 （A0A7J6KDX1） CIP3, TGME49_225020 × 7 （S8G5Q1） CF6, TGME49_245640 × 24 （A0A086KRX4） CF4, TGME49_246720 × 9 （A0A086KR31） CF3, TGME49_255895 × 7 （S8F3E8） CPH1, TGME49_266630 × 28 （A0A7J6KB56） Microtubule associated protein SPM1 × 5 （A0A7J6K285） PRP, TGME49_291880 × 35 （A0A151HK62） CF5, TGME49_297180 × 7 （S8FEB8） GUANOSINE-5'-TRIPHOSPHATE × 63 MAGNESIUM ION × 54 GUANOSINE-5'-DIPHOSPHATE × 57	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	DCXH_TOXGV
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain K0； PDBConstruct 1–256； UniProt 1–256 Author chain K1； PDBConstruct 1–256； UniProt 1–256 Author chain K2； PDBConstruct 1–256； UniProt 1–256 Author chain K3； PDBConstruct 1–256； UniProt 1–256 Author chain K4； PDBConstruct 1–256； UniProt 1–256 Author chain K5； PDBConstruct 1–256； UniProt 1–256 Author chain K6； PDBConstruct 1–256； UniProt 1–256 Author chain K7； PDBConstruct 1–256； UniProt 1–256 Author chain K8； PDBConstruct 1–256； UniProt 1–256 Author chain K9； PDBConstruct 1–256； UniProt 1–256 Author chain L0； PDBConstruct 1–256； UniProt 1–256 Author chain L1； PDBConstruct 1–256； UniProt 1–256 Author chain L2； PDBConstruct 1–256； UniProt 1–256 Author chain L3； PDBConstruct 1–256； UniProt 1–256 Author chain L4； PDBConstruct 1–256； UniProt 1–256 Author chain L5； PDBConstruct 1–256； UniProt 1–256 Author chain L6； PDBConstruct 1–256； UniProt 1–256 Author chain L7； PDBConstruct 1–256； UniProt 1–256 Author chain L8； PDBConstruct 1–256； UniProt 1–256 Author chain L9； PDBConstruct 1–256； UniProt 1–256 Author chain M1； PDBConstruct 1–256； UniProt 1–256 Author chain M2； PDBConstruct 1–256； UniProt 1–256 Author chain M3； PDBConstruct 1–256； UniProt 1–256 Author chain M4； PDBConstruct 1–256； UniProt 1–256 Author chain M5； PDBConstruct 1–256； UniProt 1–256 Author chain M6； PDBConstruct 1–256； UniProt 1–256 Author chain M7； PDBConstruct 1–256； UniProt 1–256

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	9y9z
Deposition date deposition_date	2025-09-15
Structure title title	Cryo-EM structure of conoid fiber from Toxoplasma gondii (24-nm repeat)
Keywords keywords	;Tubulin, Microtubule, Microtubule Inner Protein, Microtubule-associated Protein, Toxoplasma gondii, conoid, conoid fiber, STRUCTURAL PROTEIN ;; STRUCTURAL PROTEIN
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9y9z__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9y9z__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

9y9z__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	0.00 Å
Rg (electron density)	193.10 Å
Total Rg	193.00 Å
Atom count	806376
Residues	100974
Excluded volume	14269000 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`9y9z__assembly_1__model_1`	378-meric （378）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (17)

Entity 1 Entity 1 polymer

Description description	CF2, TGME49_258090
Molecular weight formula_weight	106251.1 kDa
Source method src_method	nat
Copy count entity_count	54

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,1,2,a,b,c,d,e,f,g,h,i,j,k,l,m,n,o,p,q,r,s,t,u,v,w,x,y,z
Atom count atom_count	806376

MATKQMLPGEGADRSSRPGTRSVARSRGTSPSSAPRLGISQELTALGSQLQALDRRQQLLFDPSVFPEDSRLAVSFPPFTRKVEDAAEAPHGAVKLRNPHRDGLDRVLGDLSKPVDLGVSLPAELQRDSFAQNDPPGRLPPALKHTSLRKLDEDAVSKFHVGVRQSARPVSYADALERTRREEDRQEKGAVRFAAATAAVAAAASAVGADADEIDCVVTVEEQAPPVCVSQGETNGGKSSGPGPGELRAEQAAAGSTVKMPADVYSAPGGAWRAAARAPSPEALAEPKVYSHSQWVDERRGEGGAPPGQFPFPRGLTEMQERMEEEWIDRERRLRADHKREMERAVAHASEKLSREYSRRLVFELQEQEKALLAQMHERHRQALAEIRCISESKTDAEEETQRFQREASAKEHQLQKVLHETRLIESEREALAAKVQHLEAENASLHASLTPLEKQACSQRAKEEDLQLRLERLKASNDRLQIQLQHEQQLAANFAQKRRGLEREVEVLDEKRAVAEREWKRVAAELRELQERQAGLCASNAHLQNELDNAIRHGRNLEQRIDEDRSKDDERQKLSQRLEKLQEEKETTERRQADEIASLRNRIKHLDAVTFQLRTMRQDFESQQLEVKRLRDENATLLAEMRHQNKGDHAMKLDQQALQNDLITVKQENADLRKEMNRLIKERNFAASGGSLPPYTPPRPNSFSTTPSPDNPLAMQLYSSEHSRGCGNACSGGGRQADPMMTEHDASVCPSLTGPLNRRCFTSDGRPRCVEDLSIPSPLSREACASPALRAQQLAVRCSTSINPVGRSTRPPPSVGAASNPLQHVHCPSAASRLGTEGDHPSYMYDGYRGDSRKATALGALAEDIPARGLAPAISLPVTAETPEQVASLESQLLLLATERRRIESELSKIPSARGRTARERQQMQHLESRLVEVDGTTHRIKQILFQAQRRKN

Entity 2 Entity 2 polymer

Description description	CF1, TGME49_222350
Molecular weight formula_weight	47976.3 kDa
Source method src_method	nat
Copy count entity_count	14

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	10,11,12,13,14,15,16,3,4,5,6,7,8,9

MQPLAREVSRLPRSGPLGPVAAKKDDKTFIPTNVRVSPGEKNDRVVKTEKIDDSTDGSGSHDGPRNLETQLEALTREVRELTLRVQEEKEMKELLNSQLNDAYEELADARSEHRVRGFAGASGARLRGVRGLPAFEARWMEPEHPTAQTAIRSQQEFELLLQEERARRHTMFEQYERHMKVMRKNHHKEKLETKKKVLSQVEFLIKKYRRLASDAVAVAKRERERVAEERKRARELAERACKNFEADLKGRTKTALEQYRRLVQEAHTAAKQEREELHNKCKELQETVDNERREFDTLIVREAEAKMAKFRASYARMKQQTEEERRQYGVMMHEIAKRVEKECAEYEEFVIRTMRDLLQSKGVEMTESGLRDFFQKKREEMRPSGEGHSSTDGLVTVKYRFQAADPEDLQ

Entity 3 Entity 3 polymer

Description description	Tubulin alpha chain
Molecular weight formula_weight	50166.6 kDa
Source method src_method	nat
Copy count entity_count	63

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	;1A,1C,1E,1G,1I,1K,1M,2A,2C,2E,2G,2I,2K,2M,3A,3C,3E,3G,3I,3K,3M,4A,4C,4E,4G,4I,4K,4M,5A,5C,5E,5G,5I,5K,5M,6A,6C,6E,6G,6I,6K,6M,7A,7C,7E,7G,7I,7K,7M,8A,8C,8E,8G,8I,8K,8M,9A,9C,9E,9G,9I,9K,9M ;

MREVISIHVGQAGIQIGNACWELFCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKHVPRCVFLDLEPTVVDEVRTGTYRHLFHPEQLISGKEDAANNFARGHYTIGKEIVDLSLDRIRKLADNCTGLQGFLMFNAVGGGTGSGLGCLLLERLSVDYGKKSKLNFCSWPSPQVSTAVVEPYNSVLSTHSLLEHTDVAVMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPASMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRMDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGIETAEGEGEEEGYGDEY

Entity 4 Entity 4 polymer

Description description	Tubulin beta chain
Molecular weight formula_weight	50119.1 kDa
Source method src_method	nat
Copy count entity_count	57

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	;1B,1D,1F,1H,1J,1L,1N,2B,2D,2F,2H,2J,2L,3B,3D,3F,3H,3J,3L,4B,4D,4F,4H,4J,4L,5B,5D,5F,5H,5J,5L,5N,6B,6D,6F,6H,6J,6L,6N,7B,7D,7F,7H,7J,7L,8B,8D,8F,8H,8J,8L,9B,9D,9F,9H,9J,9L ;

MREIVHVQGGQCGNQIGAKFWEVISDEHGIDPTGTYCGDSDLQLERINVFYNEATGGRFVPRAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVVRKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKVREEYPDRIMETFSVFPSPKVSDTVVEPYNATLSVHQLVENADEVQVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFLIGFAPLTSRGSQQYRALSVPELTQQMFDAKNMMCASDPRHGRYLTASAMFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNMKSSVCDIPPKGLKMSVTFVGNSTAIQEMFKRVSDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFDEEEGEMGAEEGA

Entity 5 Entity 5 polymer

Description description	Spindle assembly abnormal protein 6 N-terminal domain-containing protein
Molecular weight formula_weight	29530.0 kDa
Source method src_method	nat
Copy count entity_count	41

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	20,21,22,23,24,25,26,27,28,29,30,31,32,33,35,36,37,38,39,40,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62

MATNFGFGGGASGCTDSVNFLAQVDTSAIDEMDPSLADGHTLVYSREVPFEIRLQETGSSLPGDVGRLEPIRVKILILGEETNPQHVRVELTSENDLFLNYTHALNEDLFRQMQERQKLMIEFGDYPSVLIKMLNSCIKEPHCFLAVLIMHTNGKARLDFIQSMEYKFIELLCLDCVQSTEEFTRRDMTFRYNALKSKLALLQARLHDIGCLLKLKSPSLLLHLQKAAQQQAHRRQQQVAAAAPIPGKLRAPGTTEGASTRFL

Entity 6 Entity 6 polymer

Description description	CIP3, TGME49_225020
Molecular weight formula_weight	114592.6 kDa
Source method src_method	nat
Copy count entity_count	7

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	63,64,65,66,67,68,69

MATQLGRSAPLSECEFLVASGRARAPGDPSRRSVSQPSRRNGSFREGLGPRSHDRELVGHPDIDKFRSTAGPQTSRARSARAAQPETLPRFYRPSSRMAAAKNETSRELRGKPPRPTSTLKYVGCPPTEPRLRPKRTSTGLEERMLKSGGYGVRIHWDEYAGYHVHASAPEVDLMHADQVLMVRDSPTHSRESDKDAAGSPPGGLSASLSPGRKATKKAGPVHCGVSRQCIPVYQFAPTLCEKSREIIDVYRKERVAHLWKKVDARREGVVDLFQLASRAPSRKTSKLRSSGMDAKSPDDTVLSSVEERFVQACVMQFVQIAVSRTSAQLVKDGATLGPHFDDSLRFTTAGAQGSENPPVVVPTEQAVFPHPHARDPMREGLQPDAEAEGAKIERENATAIQAAKRLARQHNQVIMLNVDANLGADASATPALFVPRKKFESVALEALAHEFGNPDIDVFRDRVMCECRKLVEKVNPEEAQRFFKPYILEYSRKLDARRRRAKAQEREESGRRAASLSADGYGPQGKFPTVGLRRVENRFDEQIEHYLRKKQQLHHLKEALDEMREGQFCTFHPAVNPYPKYLKQAFRLRRSPDDPLVILERFCEQYTEDREYPRLVEAIRECTFQPNIHKFVAKEKQLQATGVEVSQEKEKGITVPGKRIKEAHKQTTEDKPAAMESRVDHLFQSIERPFDHIFAADINQWLETDANLYSSQEDGAEKRKKQRWKRWEVEGRAPQYRGALKDRSQRALLTQDGGEVVVQLVEETEERAPVVLPRHRTTPYNDWVNGLRGGYLPNVMDFQKGPTEKGDRKKAERFNMRDWSRHIRLSEREVETRIIPNEEIIDAVCESELPSAAPPPPTIWVRRRRWEPAPERGPDAPTFTEAHFHTGSDRQTDRLLPAGKPAALTQQQAKEYKNRFASSVDPTTFVVPTPLKLDRLRQQYRLYMQLRNGIETGEIRTPPKVVTLRRDVLTDLEKEVKREPPTLVLAETRDAFASDTVETDNSVDGYVCE

Entity 7 Entity 7 polymer

Description description	CF6, TGME49_245640
Molecular weight formula_weight	46600.6 kDa
Source method src_method	nat
Copy count entity_count	24

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	71,72,73,75,76,77,78,79,80,82,83,84,85,86,87,89,90,91,92,93,94,95,96,97

MNQSTIVATSVVAPQSAVSLSRAPSRPGPSESFGKQQESRPGVSGAGLAESKRVPSLTQPSLERSVTISRRKIDAVGMSLVPKLDRTTTSLAAKEEKFSSIDKIVSKPTHSFGESSKLPAGIMKTKSMFPSQTLSAPWNAPARCARKDDFGTKAWIEKLQRETTDTSQPPLERQKSQRLAQTEPVQKLKTSWLEPPQEVESGHGVAEGDDLSVAAAEYHVPETEDGKLSFKPSDPRVWNREWIHRRIHNPVLSRSNRERCAFTQSNDWLVFALHHQYVRPLRSTDWLPGEACISQRDSFQLPPGAAKYTSSSLAIPQTSWEPFIFPNPPRPFLLRNKTFNSSARTWIPSRKVKAGLVGGGTEHACNLTQHEWLDLERMLWFDSEPRLEQPYRLYADSKTCIKGSVLDIGHMMRIGW

Entity 8 Entity 8 polymer

Description description	CF4, TGME49_246720
Molecular weight formula_weight	56022.8 kDa
Source method src_method	nat
Copy count entity_count	9

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A1,A2,A3,A4,A5,A6,A7,A8,A9

MVARVVEQDVARGSGRDTLARESDEAHPPQFSLSNPHFLTAVCEELKRRDKPVTGLTTAERFNAALADMGVRYGTPEADMIMRYCQVTEDGYVIFKELMLATRQLSNVSEDHVTESLSSATQREQDRLVPLPNTSARDRDSEQGEIRDERCVYTPELTDAIRRLYAQWDRSCLRDWQFKESLQRLGVCVTPEFERLLSTYGPSGCVSFSQVMQTLMMSDSGFLASSSLRRSRNRSAADIPLPPVADRLPFYEPRRNPVTWSPPQPLKGLPVNPQDVLQHALKLPLAADLDLDRRVGSEVGDTEGGDGCSLADKFRLLKKLVALYLSERLSATQFRKELVEADVPITPELDTLIRAHEADNSGQFTPFAVAVFRAAEETEIFLKEVRRASANTEAEAHSTRDTPYIVVDKLTQVDVPSTFPAQVEEEEDLKASARHMLEAGVKYPTEKEAFVGESKLGDIPKGNYIPSDYGMSQHATLALANRAAAHHAYHGHGNIITWGKSC

Entity 9 Entity 9 polymer

Description description	CF3, TGME49_255895
Molecular weight formula_weight	62988.6 kDa
Source method src_method	nat
Copy count entity_count	7

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B1,B2,B3,B4,B5,B6,B7

MTTASAIIGPSGGRDALMARQLYPNFFKTRAGDPPERGATRKDLRASMMDRKSILYPIPYLESEASRATWTQRATRGVPHLSTFSLAHAEPGGDIERDEIRETVASLLEVQPSGAQPLSVVYKRHDLEPLPPSISFRPHHNLADPVYYDMPPSPPYPAPPLLLKEQRRQKSLWSPLCNAESPEKRPHSIVFNPGCSFLSVTRGCRRGRRSNSAASEVSFQEVTGEPYHDLVQAESLRSRHRGREAAQLLSSRLGSLDEPQTNRHFPSPERRRKRAGATLGILPSRSVSVSAGSHRGRCRSSYPEESVPIPMPFWGRYDWYPPMKAPRQRIQAFGRPASRECVPLYESGLDDWTTFPWNETLRTTGHRSLTSEDRSPSTRFSPHRGSLRATGDNADLEWRMDRSTNFGELQSRIADASRGQQKFYRRQKASLWGALHPATQRVVGTFPRTECSFVCKEHRGRHVHLMDVFGPVERNRLSSYFDQDEADEIHRRARGCLGVHTASCPQSHNTLRKVLSDCAERGKPSDLDAFPQQTREPKRHWWSPAEPLADYADEKS

Entity 10 Entity 10 polymer

Description description	CPH1, TGME49_266630
Molecular weight formula_weight	67410.5 kDa
Source method src_method	nat
Copy count entity_count	28

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C0,C6,C7,C8,C9,D0,D1,D2,D3,D4,D5,D6,D7,D8,D9,E0,E1,E2,E3,E4,E5,E6,E7,E8,E9,F1,F2,F3

MSRAYADLVVSRKAKAPPFSVDNNDGRPKRPNRVWFDRDRAKACNDMRREYPLHYYISSYDVYAFLATLRQGADPAKRDAAGRTPLDLAVQMAVELIETSLCTSFPIDNIDVTPAATLKPAKDSPPESRPETFTNPFRVKYRDANASMYVQHDIMRYRCADSDVYKSCREPPFPLPSDGHDGAERTYQVATFPPQEFRIKNGDSEDFFRDQQRARRTQSPSFPLPRGDVSRYYAAAHNLRPQQFAYAYDANGKPMSWSRLQREQVQLEQEHLQGEFLVAVEQFLERPPSKAAMSQMRELIRRLNLMMVIIKKYELCLPLKREAAEKAKAYIGTALTYPYLYTASMYEAFKRYPRTPAGQAWDALNPADSRRLVLIILSLKMHGHELFSFMGTVCRLFNSLMEQLGLCDDRCGTGGHWCKLGSECSQFYLHMAFSLDDAQLFQKFITQQQLFDKQDIFKWEDLLYTLMQHRERFRPYFAALLARRLKARVQKRLMNSADQQAYLPETVKYPCEERYFTRQLLGEYSEIFGESEAEEFNSMLRHWRYGAARQAPGTGSEEDNILPAPLPPVSESPAADFWSLRD

Entity 11 Entity 11 polymer

Description description	Microtubule associated protein SPM1
Molecular weight formula_weight	38845.8 kDa
Source method src_method	nat
Copy count entity_count	5

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C1,C2,C3,C4,C5

MSGGNSNTPKKLPSEEGSDYGYPQKPQKYLPKSEQAEPDYSACCKGNDAYKGASHGTVQFSHPEEAQKYAGAAAGAETIQRGRERVAADRQPRAAGDVPARRLHLSDVDEAHRGQSPSRHPGYCVEELCTCGMHKCIPSRAPVPFTGSTQYRQEFVPKPLPPPTQVSQVTLPPSLPFEAESSYRTEFVAKPLPPPAKFSEVKLPPTLPFHGESAYRTDYVPKPLPEVAKPVEVKLPPTLPFNAQSCYRSEYVAKPLPPPVQTVEVKLPPSLPFEGSTHYRDEFQVKPLPPATKVTEVKLPPSLPFDATSMYRSDYVAKSNPICPVSKLPQYPAATYPQNHVFWDPDTKQWY

Entity 12 Entity 12 polymer

Description description	PRP, TGME49_291880
Molecular weight formula_weight	80452.4 kDa
Source method src_method	nat
Copy count entity_count	35

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F0,F5,F6,F7,F8,F9,G0,G1,G2,G3,G4,G5,G6,G7,G8,G9,H0,H1,H2,H3,H4,H5,H6,H7,H8,H9,I1,I2,I3,I4,I5,I6,I7,I8,I9

MLARGDDELCSSFYRSANKHIRGVGGEPPASSRADLRRYMPGYTAPPSLNAYKAWHVNSATLRRENDRLKAENKNIERDFDRLYQRAYIAEVQLNNLKAAASKIPLGGANYSVTQLVKLAANLLELLTKQPEQTCVSVIPDALACLSMCHVRDRRLFAAGEKLKRTLQCPSGASGYNGNESKTRPIGRPAGEVAPDLKWLATVSDDLSWLKWADQWDVLPMDLRWISIAVDDRSLLLHRFLWTRAPVDLRYLTVVSGNMDWLYIGPDRWYSTPMQLRLRAIALEDPTIIKPTMAEAALYGLEREKIANTLIPDADLPNLPSPHAPEEDLDLTLRISLSPADIAVCENNGGIASSAKAGASTGTPGMPTPGSKVGQAKETSASSKVGMAKTVPSPLSKTAPPLKADPSEPVPTKVGGGSVGGPKATPSPSKAGPPPKDSDKPGGVAKKASPTPPSKAEGVAASGSGDAPEEPKSVKGAPLGKKGPGPLGVKGGSPLPPPGDAKGKASPESATAKGPAELPKGPAGAAKAAVPGKAAPVGPGKGPAAPLGKKAPGEPVGKPKAEMKKSSPPVGEPKAEVKKSPPPPSGSPKAESKKSPSPPLGEPKADVKKSPPPPLGGPKAEMKKSPPGASPAAPKADSSTPAAPTGATPPKAKLGAPPGKAPTAGTAEGKEAAPAKKGPLPAKGAEPLGKKGPPPVAKAEDTTKPPPPTAGQNDDADGAGVSAKKQSPLGKGPPPKKGPLLGKKIPPAPDARDAKADDASPAKKGPPKGLPKGKAPPKGKGFL

Entity 13 Entity 13 polymer

Description description	CF5, TGME49_297180
Molecular weight formula_weight	97829.7 kDa
Source method src_method	nat
Copy count entity_count	7

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J1,J2,J3,J4,J5,J6,J7

MSRERLGPSRLGRHTPAAASARGDPRLLVEAETPTDRGRIVKASLHTQGDVEFLEGRLRDKVCVDKWVTVQERASPAEGKRESEGKRESEGRRESPRMTSTSAGLEPAEAWREDIFGKEERYDMARFDEEDASAEDAVRTAPRPSPQRQFQVRHKVTVEGVVPTSASVRMQRRLAQRRGKRFFSTDEGLYWQKLQRSKPQKSREDALKFVATFMQEGELLVNSVSMEEDPSVRLRRLAALRLLRNSPADRVPGSISGRLLIPYDHADVRELLRVSSFCSGEAWRVLEEIRRLLVLRKGRLFLASDRNATASRHCLAFLASLKKNLEAAARNLVRQGRLRRPSARLQQSEGRKRAPTLDRDEAWERREGLVREIRRTLSLAAAYSTKGKKQPVVYIQLAALKPSIVADFLTPAEVAVILTEVFQNLWTKFVEYSLRRRVRVSTAALVLDFSGLTEFELASSASHFLLSSLRDVVRAFAPLLIKKIIFYNSAKAGEFLWEALRPGVEHSCFFSFCSSEEDLETEIESERTMVYHTTGLANDMSLIAHRCPLYALYGPPLPPPDSLFPLRAPGFLPASAPASALQKSPLSRPKAGAFRQLFALLGAARVRLVPTAEDAETGGSNLPRAPFFRTAGESRERENAGLARGGEEDEETETLRRGDEEIQKTCREEEAKFWRGMNCFHDLVVEAARAKRIAERERQADVVESARQTRPAEAKPDEADEDAEELDLDSVDVIDPDANLGPSEESLECAAAAVAQDGDRVDLGKSHAERSFERIFTAQGDLEETLEGIGSPFENAWERSVQEAFDASVKAIREEHLPLSAARVELPRVSRPARTFPTPLDRVFRRPLYLHLSAEAGGNWERELLGADRAK

Entity 14 Entity 14 polymer

Description description	DCX, TGME49_256030
Molecular weight formula_weight	29261.4 kDa
Source method src_method	nat
Copy count entity_count	27

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K0,K1,K2,K3,K4,K5,K6,K7,K8,K9,L0,L1,L2,L3,L4,L5,L6,L7,L8,L9,M1,M2,M3,M4,M5,M6,M7

MACGIPWKLARRDELMATRQAERPGEYFPPPYPPCPPTVVTPLRTSAYDFPEATFVTRPCLPAKKATGHKNVFERLTDTAYYTGSHRERFDEFGNGRGIAGREYLYAYDGLTESPSRCHEVYSSVIKRPRKPVVTPGTLGIQRFGVQIPAPRLMWLYRNGDKHDDGTPFFVRPYIKSMESLYQQITKEITPIAGPVRRIFDQNFRVITDLDDIVDGAKYLCTSGEPPAAYDRLEKFLSEWVIQKSQTKVPSQFFVV

Entity 15 Entity 15 non-polymer

Description description	GUANOSINE-5'-TRIPHOSPHATE
Molecular weight formula_weight	523.2 kDa
Source method src_method	syn
Copy count entity_count	63

Entity 16 Entity 16 non-polymer

Description description	MAGNESIUM ION
Molecular weight formula_weight	24.3 kDa
Source method src_method	syn
Copy count entity_count	54

Entity 17 Entity 17 non-polymer

Description description	GUANOSINE-5'-DIPHOSPHATE
Molecular weight formula_weight	443.2 kDa
Source method src_method	syn
Copy count entity_count	57

▶

Resolution resolution	3.14 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	95409

Cryo-EM structure of conoid fiber from Toxoplasma gondii (24-nm repeat)

1. Protein Identity and Related Structures Protein Identity & Related Structures

CF2, TGME49_258090

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

CF1, TGME49_222350

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Tubulin alpha chain

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Tubulin beta chain

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Spindle assembly abnormal protein 6 N-terminal domain-containing protein

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

CIP3, TGME49_225020

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

CF6, TGME49_245640

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

CF4, TGME49_246720

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

CF3, TGME49_255895

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

CPH1, TGME49_266630

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer