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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：O14776 New Search
29PDB entries
31Biological assembly
34chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2DK7 Solution structure of WW domain in transcription elongation regulator 1 Deposited 2006-04-06 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 520–579（60 aa） Fragment：WW domain
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7；298 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition 0.8mM U-15N, 13C; 20mM phosphate buffer NA; 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 90%H2O,10%D2O | 90% H2O/10% D2O
Resolution not provided
2DOD Solution structure of the first FF domain of human transcription factor CA150 Deposited 2006-04-28 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 651–719（69 aa） Fragment：FF domain
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7；298 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition 1.2mM 13C/15N-PROTEIN; 20mM d-Tris-HCl(pH7.0); 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 90% H2O, 10% D2O | 90% H2O/10% D2O
Resolution not provided
2DOE Solution structure of the third FF domain of human transcription factor CA150 Deposited 2006-04-28 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 784–853（70 aa） Fragment：FF domain
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7；298 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition 1.1mM 13C/15N-PROTEIN; 20mM d-Tris-HCl(pH7.0); 100mM NaCl; 1mM d-DTT; 0.02% NaN3;90% H2O, 10% D2O | 90% H2O/10% D2O
Resolution not provided
2DOF Solution structure of the fourth FF domain of human transcription factor CA150 Deposited 2006-04-28 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 888–959（72 aa） Fragment：FF domain
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7；298 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition 1.1mM 13C/15N-PROTEIN, 20mM d-Tris-HCl(pH7.0), 100mM NaCl, 1mM d-DTT, 0.02% NaN3, 10% D2O | 90% H2O/10% D2O
Resolution not provided
2E71 Solution structure of the second FF domain of human transcription factor CA150 Deposited 2007-01-05 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 717–786（70 aa） Fragment：FF domain
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7；298 K；Ionic strength (raw mmCIF value) 120mM；Pressure ambient
NMR sample composition 20mM d-Tris-HCl(pH7.0); 100mM NaCl; 1mM d-DTT; 0.02% NaN3; 90% H2O, 10% D2O | 90% H2O/10% D2O
Resolution not provided
2KIQ Solution structure of the FF Domain 2 of human transcription elongation factor CA150 Deposited 2009-05-07 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 724–782（59 aa） Fragment：UNP residues 724-782
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 7；303 K；Ionic strength (raw mmCIF value) 25；Pressure ambient
NMR sample composition 1 mM [U-100% 15N] CA150 FF2-1, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition 1 mM [U-100% 13C; U-100% 15N] CA150 FF2-2, 100% D2O | 100% D2O
Resolution not provided
2KIS Solution structure of CA150 FF1 domain and FF1-FF2 interdomain linker Deposited 2009-05-08 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 659–724（66 aa） Fragment：FF1 domain: UNP residues 659-724
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；285 K；Ionic strength (raw mmCIF value) 0.137；Pressure ambient
NMR sample composition 1-1.7 mM [U-99% 13C; U-99% 15N] protein, 95% H2O/5% D2O | 95% H2O/5% D2O
Resolution not provided
2MW9 NMR structure of FBP28 WW2 Y438R mutant Deposited 2014-11-03 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 428–464（37 aa） Fragment：WW 2 domain residues 428-464
Mutation：Y438R No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；285 K；Pressure ambient
NMR sample composition 0.7 mM protein, 100 mM sodium chloride, 20 mM sodium phosphate, 1 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2MWA NMR structure of FBP28 WW2 mutant Y446L Deposited 2014-11-03 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 428–464（37 aa） Fragment：WW 2 domain residues 430-466
Mutation：Y446L No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；285 K；Pressure ambient
NMR sample composition 0.7 mM protein, 100 mM sodium chloride, 20 mM sodium phosphate, 1 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2MWB FBP28 WW2 mutant W457F Deposited 2014-11-03 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 428–464（37 aa） Fragment：WW 2 domain residues 430-466
Mutation：W457F No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；285 K；Pressure ambient
NMR sample composition 0.7 mM protein, 100 mM sodium chloride, 20 mM sodium phosphate, 1 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2MWD NMR structure of FBP28 WW2 mutant Y438R DNDC Deposited 2014-11-04 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 433–460（28 aa） Fragment：WW 2 domain residues 433-460
Mutation：Y438R No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；285 K；Pressure ambient
NMR sample composition 0.7 mM protein, 100 mM sodium chloride, 20 mM sodium phosphate, 1 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2MWE NMR structure of FBP28 WW2 mutant Y438R, L453A DNDC Deposited 2014-11-04 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 433–460（28 aa） Fragment：WW 2 domain residues 433-460
Mutation：Y238R, L453A No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；285 K；Pressure ambient
NMR sample composition 0.7 mM protein, 100 mM sodium chloride, 20 mM sodium phosphate, 1 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2MWF NMR structure of FBP28 WW2 mutant Y438R DN Deposited 2014-11-04 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 433–464（32 aa） Fragment：WW 2 domain residues 433-464
Mutation：Y438R No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；285 K；Pressure ambient
NMR sample composition 0.7 mM protein, 100 mM sodium chloride, 20 mM sodium phosphate, 1 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2N4R NMR structure of Fbp28 WW domain L453D mutant Deposited 2015-07-01 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 428–464（37 aa）
Mutation：L453D No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.8；285 K；Pressure ambient
NMR sample composition 500-1000 uM protein, 25 mM sodium phosphate, 100 mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2N4S NMR structure of Fbp28 WW domain L453E mutant Deposited 2015-07-01 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 428–464（37 aa）
Mutation：L453E No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.8；285 K；Pressure ambient
NMR sample composition 500-1000 uM protein, 25 mM sodium phosphate, 100 mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2N4T NMR structure of Fbp28 WW domain L453W mutant Deposited 2015-07-01 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 428–464（37 aa）
Mutation：L453W No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.8；285 K；Pressure ambient
NMR sample composition 500-1000 uM protein, 25 mM sodium phosphate, 100 mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2N4U NMR structure of Fbp28 WW domain E454Y mutant Deposited 2015-07-01 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 428–464（37 aa）
Mutation：E454Y No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.8；285 K；Pressure ambient
NMR sample composition 500-1000 uM protein, 25 mM sodium phosphate, 100 mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2N4V NMR structure of Fbp28 WW domain T456D mutant Deposited 2015-07-01 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 428–464（37 aa）
Mutation：T456D No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.8；285 K；Pressure ambient
NMR sample composition 500-1000 uM protein, 25 mM sodium phosphate, 100 mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2N4W NMR structure of Fbp28 WW domain T456Y mutant Deposited 2015-07-01 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 428–464（37 aa）
Mutation：T456Y No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 5.8；285 K；Pressure ambient
NMR sample composition 500-1000 uM protein, 25 mM sodium phosphate, 100 mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
2NNT General structural motifs of amyloid protofilaments Deposited 2006-10-24 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 428–464（37 aa） Fragment：second WW domain
Chain B 428–464（37 aa） Fragment：second WW domain
Chain C 428–464（37 aa） Fragment：second WW domain
Chain D 428–464（37 aa） Fragment：second WW domain
Mutation：Y446F Mutation：Y446F Mutation：Y446F Mutation：Y446F No recorded non-water small molecule SOLID-STATE NMR
NMR measurement conditions pH 7；285 K；Pressure 1
NMR sample composition uniform 13C,15N labeling, 15 mg fibre in phosphate buffer | phosphate buffer
NMR sample composition uniform 2H,13C,15N labeling, 15 mg fibre in phosphate buffer | phosphate buffer
NMR sample composition uniform 15N labeling, 13C labeling is based on 1,3[13C]-glycerol as carbon source for the bacteria, 15 mg fibre in phosphate buffer | phosphate buffer
NMR sample composition uniform 15N labeling, 13C labeling is based on 2[13C]-glycerol as carbon source for the bacteria, 15 mg fibre in phosphate buffer | phosphate buffer
Resolution not provided
3HFH Crystal structure of tandem FF domains Deposited 2009-05-11 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 661–845（185 aa） Fragment：FF domains: UNP residues 661-845
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；50mM Bis-Tris pH 6.5, 50 mM Ammonium sulfate, 30% Pentaerythritol ethoxylate, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.70 Å R-free 0.283
3HFH Crystal structure of tandem FF domains Deposited 2009-05-11 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 661–845（185 aa） Fragment：FF domains: UNP residues 661-845
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；50mM Bis-Tris pH 6.5, 50 mM Ammonium sulfate, 30% Pentaerythritol ethoxylate, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.70 Å R-free 0.283
3Q1I Polo-like kinase I Polo-box domain in complex with FMPPPMSpSM phosphopeptide from TCERG1 Deposited 2010-12-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain E 99–107（9 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) 1PE PENTAETHYLENE GLYCOL × 1 PEG DI(HYDROXYETHYL)ETHER × 1 PG0 2-(2-METHOXYETHOXY)ETHANOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；30% PEG400, 0.1M MES, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 1.40 Å R-free 0.222
4FQG Crystal structure of the TCERG1 FF4-6 tandem repeat domain Deposited 2012-06-25 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 895–1081（187 aa） Fragment：TCERG1 FF4-6 tandem repeat domain (unp residues 895:1081)
Not recorded NI NICKEL (II) ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9；277 K；0.016 M NiCl2, 0.1 M Tris-HCl, 16% polyethylene glycol monomethyl ether 2000, and 0.13 M glycine, pH 9, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.00 Å R-free 0.241
4FQG Crystal structure of the TCERG1 FF4-6 tandem repeat domain Deposited 2012-06-25 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 895–1081（187 aa） Fragment：TCERG1 FF4-6 tandem repeat domain (unp residues 895:1081)
Not recorded NI NICKEL (II) ION × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9；277 K；0.016 M NiCl2, 0.1 M Tris-HCl, 16% polyethylene glycol monomethyl ether 2000, and 0.13 M glycine, pH 9, VAPOR DIFFUSION, HANGING DROP, temperature 277K
Resolution 2.00 Å R-free 0.241
7ABF Human pre-Bact-1 spliceosome core structure Deposited 2020-09-07 Assembly 1 Protein–RNA Heteromer；Protein × 12 PDB declaration: pentadecameric（15） Consistent with all polymers
Chain A4 1–1077（1077 aa）
Not recorded IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.90 Å
7ABG Human pre-Bact-1 spliceosome Deposited 2020-09-07 Assembly 1 Protein–RNA Heteromer；Protein × 54 PDB declaration: 58-meric（58） Consistent with all polymers
Chain A4 1–1098（1098 aa）
Not recorded IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 GTG 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.80 Å
8Q7N cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) Deposited 2023-08-16 Assembly 1 Protein–RNA Heteromer；Protein × 17 PDB declaration: 21-meric（21） Consistent with all polymers
Chain T 1–1098（1098 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
8QO9 Cryo-EM structure of a human spliceosomal B complex protomer Deposited 2023-09-28 Assembly 1 Protein–RNA Heteromer；Protein × 66 PDB declaration: 71-meric（71） Consistent with all polymers
Chain T 1–1098（1098 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.29 Å
9R3D Cryo-EM structure of the human pre-Bact-OTS complex (whole map) Deposited 2025-05-04 Assembly 1 Protein–RNA Heteromer；Protein × 14 PDB declaration: 17-meric（17） Consistent with all polymers
Chain T 1–1098（1098 aa）
Not recorded IHP INOSITOL HEXAKISPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.12 Å
9R8V Cryo-EM structure of the human pre-Bact-OTS complex (whole map) Deposited 2025-05-17 Assembly 1 Protein–RNA Heteromer；Protein × 59 PDB declaration: 63-meric（63） Consistent with all polymers
Chain T 1–1098（1098 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.9
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 8.50 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.