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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q02821 New Search
11PDB entries
17Biological assembly
18chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1BK5 KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE Deposited 1998-07-14 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 89–510（422 aa） Fragment：ARMADILLO DOMAIN
Chain B 89–510（422 aa） Fragment：ARMADILLO DOMAIN
Not recorded CO COBALT (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；pH 7.0
Resolution 2.20 Å R-free 0.276
1BK6 KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS Deposited 1998-07-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 89–510（422 aa） Fragment：ARMADILLO DOMAIN
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；pH 7.0
Resolution 2.80 Å R-free 0.307
1BK6 KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS Deposited 1998-07-14 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 89–510（422 aa） Fragment：ARMADILLO DOMAIN
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；pH 7.0
Resolution 2.80 Å R-free 0.307
1EE4 CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE Deposited 2000-01-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 87–509（423 aa） Fragment：ARMADILLO DOMAIN
Mutation：Y397D No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.10 Å R-free 0.277
1EE4 CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE Deposited 2000-01-30 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 87–509（423 aa） Fragment：ARMADILLO DOMAIN
Mutation：Y397D No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.10 Å R-free 0.277
1EE5 YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A NUCLEOPLASMIN NLS PEPTIDE Deposited 2000-01-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 87–510（424 aa） Fragment：ARMADILLLO-REPEAT DOMAIN
Mutation：Y397D No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.40 Å R-free 0.265
1UN0 Crystal Structure of Yeast Karyopherin (Importin) alpha in complex with a Nup2p N-terminal fragment Deposited 2003-09-03 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 88–530（443 aa） Fragment：ARMADILLO REPEAT DOMAIN, RESIDUES 88-530
Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.8；50 MM HEPES PH 6.8, 0.15 M NACL, 24 % PEG3350, 2 % PEG400
Resolution 2.60 Å R-free 0.257
1UN0 Crystal Structure of Yeast Karyopherin (Importin) alpha in complex with a Nup2p N-terminal fragment Deposited 2003-09-03 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 88–530（443 aa） Fragment：ARMADILLO REPEAT DOMAIN, RESIDUES 88-530
Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.8；50 MM HEPES PH 6.8, 0.15 M NACL, 24 % PEG3350, 2 % PEG400
Resolution 2.60 Å R-free 0.257
2C1T Structure of the Kap60p:Nup2 complex Deposited 2005-09-20 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 88–541（454 aa） Fragment：ARM DOMAIN, RESIDUES 88-541
Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.8；EXPERIMENTAL DETALS GIVEN IN ENTRY 1UN0 AND IN MATSUURA ET AL, EMBO J, 22, 5358, 2003., pH 6.80
Resolution 2.60 Å R-free 0.251
2C1T Structure of the Kap60p:Nup2 complex Deposited 2005-09-20 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 88–541（454 aa） Fragment：ARM DOMAIN, RESIDUES 88-541
Mutation：YES No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.8；EXPERIMENTAL DETALS GIVEN IN ENTRY 1UN0 AND IN MATSUURA ET AL, EMBO J, 22, 5358, 2003., pH 6.80
Resolution 2.60 Å R-free 0.251
4PVZ Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2 Deposited 2014-03-18 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 88–509（422 aa） Fragment：unp residues 88-509
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；100 mM ammonium acetate, 20% PEG 8000, 100 mM BisTris, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.50 Å R-free 0.226
4PVZ Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2 Deposited 2014-03-18 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 88–509（422 aa） Fragment：unp residues 88-509
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；100 mM ammonium acetate, 20% PEG 8000, 100 mM BisTris, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.50 Å R-free 0.226
4XZR Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh1 Deposited 2015-02-04 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 88–509（422 aa） Fragment：unp residues 88-509
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；100 mM ammonium acetate, 20% PEG 8000, 100 mM BisTris
Resolution 2.25 Å R-free 0.215
5H2W Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-340) Deposited 2016-10-18 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 88–510（423 aa） Fragment：UNP residues 88-510
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；0.1M MES, 0.1M calcium acetate, 12% PEG8000
Resolution 2.50 Å R-free 0.247
5H2W Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-340) Deposited 2016-10-18 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 88–510（423 aa） Fragment：UNP residues 88-510
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；0.1M MES, 0.1M calcium acetate, 12% PEG8000
Resolution 2.50 Å R-free 0.247
5H2X Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-172) Deposited 2016-10-18 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 88–510（423 aa） Fragment：UNP residues 88-510
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；293 K；0.1M sodium phosphate, 12% PEG8000
Resolution 2.20 Å R-free 0.228
5T94 Crystal structure of Kap60 bound to yeast RCC1 (Prp20) Deposited 2016-09-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–542（542 aa）
Mutation：T205A, D276E, K400R No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；289 K；0.1 M Na cacodylate, 0.1 M NaCl and 1.1 M ammonium sulfate
Resolution 2.63 Å R-free 0.259

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.