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1cbw

BOVINE CHYMOTRYPSIN COMPLEXED TO BPTI

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

BOVINE CHYMOTRYPSIN

OrganismNot specified

UniProt P00767

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 BOVINE CHYMOTRYPSIN × 1 （P00766） BOVINE CHYMOTRYPSIN × 1 （P00766） BPTI × 1 （P00974） water × 4 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 4 BOVINE CHYMOTRYPSIN × 1 （P00766） BOVINE CHYMOTRYPSIN × 1 （P00766） BPTI × 1 （P00974） SULFATE ION × 2 water × 4 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 8 BOVINE CHYMOTRYPSIN × 2 （P00766） BOVINE CHYMOTRYPSIN × 2 （P00766） BPTI × 2 （P00974） SULFATE ION × 2 water × 8 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1cbw 1cbw 1cbw

3 assemblies

View Construct and Data Evidence
UniProt name CTRB_BOVIN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–13； UniProt 1–13 Author chain F； PDBConstruct 1–13； UniProt 1–13

BOVINE CHYMOTRYPSIN

OrganismNot specified

UniProt P00766

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 BOVINE CHYMOTRYPSIN × 1 （P00767） BPTI × 1 （P00974） water × 4 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 4 BOVINE CHYMOTRYPSIN × 1 （P00767） BPTI × 1 （P00974） SULFATE ION × 2 water × 4 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 8 BOVINE CHYMOTRYPSIN × 2 （P00767） BPTI × 2 （P00974） SULFATE ION × 2 water × 8 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1chg 1ex3 1k2i

3 assemblies

Homodimer
1gcd 1k2i 1oxg 2cga 4q2k 4q2k 7kty 7ktz 7ku0 7ku1 7ku2 7ku3

12 assemblies

Homotetramer

None

Other homooligomers
1afq 1gg6 1ggd 1ggd 1ggd 1gmh 1gmh 1gmh 1vgc 1vgc 1vgc 1yph

44 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
1ab9 1ab9 1ab9 1acb 1ca0 1ca0 1cbw 1cbw 1cbw 1cgi 1cgj 1cho

119 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name CTRA_BOVIN
Isoform —
PDB entities 2, 3
Chains and sequence ranges Author chain B； PDBConstruct 1–131； UniProt 16–146 Author chain G； PDBConstruct 1–131； UniProt 16–146 Author chain C； PDBConstruct 1–97； UniProt 149–245 Author chain H； PDBConstruct 1–97； UniProt 149–245

BPTI

OrganismNot specified

UniProt P00974

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 BOVINE CHYMOTRYPSIN × 1 （P00767） BOVINE CHYMOTRYPSIN × 1 （P00766） BOVINE CHYMOTRYPSIN × 1 （P00766） water × 4 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 4 BOVINE CHYMOTRYPSIN × 1 （P00767） BOVINE CHYMOTRYPSIN × 1 （P00766） BOVINE CHYMOTRYPSIN × 1 （P00766） SULFATE ION × 2 water × 4 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 8 BOVINE CHYMOTRYPSIN × 2 （P00767） BOVINE CHYMOTRYPSIN × 2 （P00766） BOVINE CHYMOTRYPSIN × 2 （P00766） SULFATE ION × 2 water × 8 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1aal 1aal 1bpi 1bpt 1bti 1fan 1g6x 1jv8 1jv9 1k6u 1ld5 1ld6

59 assemblies; showing the first 12

Homodimer
1g6x 1k09 2zjx 2zvx

4 assemblies

Homotetramer

None

Other homooligomers
1b0c 1bhc 1bz5 2hex 2hex 3ldi 3ldm 6f1f

8 assemblies

Heteromeric or nucleic-acid complex
1brb 1bth 1bth 1bzx 1cbw 1cbw 1cbw 1co7 1d0d 1eaw 1eaw 1ejm

195 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name BPT1_BOVIN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D； PDBConstruct 1–58； UniProt 36–93 Author chain I； PDBConstruct 1–58； UniProt 36–93

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1cbw
Deposition date deposition_date1996-12-22
Structure title titleBOVINE CHYMOTRYPSIN COMPLEXED TO BPTI
Keywords keywords;SERINE PROTEASE, INHIBITOR, PROTEASE-SUBSTRATE INTERACTIONS, COMPLEX (SERINE PROTEASE-INHIBITOR), COMPLEX (SERINE PROTEASE-INHIBITOR) complex ;; COMPLEX (SERINE PROTEASE/INHIBITOR)
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1cbw__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1cbw__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1cbw__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）19.81 Å
Rg (electron density)18.80 Å
Total Rg19.79 Å
Atom count2210
Residues297
Excluded volume39286 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1cbw__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1cbw__assembly_2__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 1cbw__assembly_3__model_1 octameric （8） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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6. Fold Classification (SCOP + CATH) 10 domains

SCOP 2.08 (4 domains)

Domain ID domain_idd1cbw.1
Class classb — All beta proteins
Fold Fold foldb.47 — Trypsin-like serine proteases
Superfamily Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
Family Family familyb.47.1.2 — Eukaryotic proteases
Domain ID domain_idd1cbw.2
Class classb — All beta proteins
Fold Fold foldb.47 — Trypsin-like serine proteases
Superfamily Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
Family Family familyb.47.1.2 — Eukaryotic proteases
Domain ID domain_idd1cbwd_
Class classg — Small proteins
Fold Fold foldg.8 — BPTI-like
Superfamily Superfamily superfamilyg.8.1 — BPTI-like
Family Family familyg.8.1.1 — Small Kunitz-type inhibitors & BPTI-like toxins
Domain ID domain_idd1cbwi_
Class classg — Small proteins
Fold Fold foldg.8 — BPTI-like
Superfamily Superfamily superfamilyg.8.1 — BPTI-like
Family Family familyg.8.1.1 — Small Kunitz-type inhibitors & BPTI-like toxins

CATH v4.4 (6 domains)

Domain ID domain_id1cbwB00
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology10 — Thrombin, subunit H
Homologous superfamily homologous superfamily10 — Trypsin-like serine proteases
Domain ID domain_id1cbwC00
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology10 — Thrombin, subunit H
Homologous superfamily homologous superfamily10 — Trypsin-like serine proteases
Domain ID domain_id1cbwD00
Class class4 — Few Secondary Structures
Architecture architecture10 — Irregular
Topology topology410 — Factor Xa Inhibitor
Homologous superfamily homologous superfamily10 — Pancreatic trypsin inhibitor Kunitz domain
Domain ID domain_id1cbwG00
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology10 — Thrombin, subunit H
Homologous superfamily homologous superfamily10 — Trypsin-like serine proteases
Domain ID domain_id1cbwH00
Class class2 — Mainly Beta
Architecture architecture40 — Beta Barrel
Topology topology10 — Thrombin, subunit H
Homologous superfamily homologous superfamily10 — Trypsin-like serine proteases
Domain ID domain_id1cbwI00
Class class4 — Few Secondary Structures
Architecture architecture10 — Irregular
Topology topology410 — Factor Xa Inhibitor
Homologous superfamily homologous superfamily10 — Pancreatic trypsin inhibitor Kunitz domain
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7. Citations (2)