Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | KU80 × 1 （P13010） water × 2 | Consistent with protein count |
| UniProt name | KU70_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–609； UniProt 0–608 |
Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | KU70 × 1 （P12956） water × 2 | Consistent with protein count |
| UniProt name | KU86_HUMAN |
| Isoform | — |
| PDB entities | 2 |
| Chains and sequence ranges | Author chain B； PDBConstruct 1–565； UniProt 0–564 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 1jeq |
| Deposition date deposition_date | 2001-06-18 |
| Structure title title | Crystal Structure of the Ku Heterodimer |
| Keywords keywords | ;double-strand DNA break repair, non-homologous end-joining, alpha/beta domain, beta barrel, helical C-terminal arm, sap domain, DNA BINDING PROTEIN ;; DNA BINDING PROTEIN |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 36.24 Å |
| Rg (electron density) | 35.43 Å |
| Total Rg | 35.90 Å |
| Atom count | 8591 |
| Residues | 1068 |
| Excluded volume | 154550 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d1jeqa1 |
| Class class | a — All alpha proteins |
| Fold Fold fold | a.140 — LEM/SAP HeH motif |
| Superfamily Superfamily superfamily | a.140.2 — SAP domain |
| Family Family family | a.140.2.1 — SAP domain |
| Domain ID domain_id | d1jeqa3 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.131 — SPOC domain-like |
| Superfamily Superfamily superfamily | b.131.1 — SPOC domain-like |
| Family Family family | b.131.1.1 — Ku70 subunit middle domain |
| Domain ID domain_id | d1jeqa4 |
| Class class | c — Alpha and beta proteins (a/b) |
| Fold Fold fold | c.62 — vWA-like |
| Superfamily Superfamily superfamily | c.62.1 — vWA-like |
| Family Family family | c.62.1.3 — Ku70 subunit N-terminal domain |
| Domain ID domain_id | d1jeqb1 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.131 — SPOC domain-like |
| Superfamily Superfamily superfamily | b.131.1 — SPOC domain-like |
| Family Family family | b.131.1.2 — Ku80 subunit middle domain |
| Domain ID domain_id | d1jeqb2 |
| Class class | c — Alpha and beta proteins (a/b) |
| Fold Fold fold | c.62 — vWA-like |
| Superfamily Superfamily superfamily | c.62.1 — vWA-like |
| Family Family family | c.62.1.4 — Ku80 subunit N-terminal domain |
| Domain ID domain_id | 1jeqA01 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| Topology topology | 50 — Rossmann fold |
| Homologous superfamily homologous superfamily | 410 — von Willebrand factor, type A domain |
| Domain ID domain_id | 1jeqA02 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 40 — Beta Barrel |
| Topology topology | 290 — Ku70; Chain: A; Domain 2 |
| Homologous superfamily homologous superfamily | 10 — |
| Domain ID domain_id | 1jeqA03 |
| Class class | 4 — Few Secondary Structures |
| Architecture architecture | 10 — Irregular |
| Topology topology | 970 — Ku70, bridge and pillars |
| Homologous superfamily homologous superfamily | 10 — Ku70, bridge and pillars |
| Domain ID domain_id | 1jeqA04 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 1600 — Ku70; Chain: A; domain 4 |
| Homologous superfamily homologous superfamily | 10 — |
| Domain ID domain_id | 1jeqA05 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 720 — Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 |
| Homologous superfamily homologous superfamily | 30 — SAP domain |
| Domain ID domain_id | 1jeqB01 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| Topology topology | 50 — Rossmann fold |
| Homologous superfamily homologous superfamily | 410 — von Willebrand factor, type A domain |
| Domain ID domain_id | 1jeqB02 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 40 — Beta Barrel |
| Topology topology | 290 — Ku70; Chain: A; Domain 2 |
| Homologous superfamily homologous superfamily | 10 — |
| Domain ID domain_id | 1jeqB03 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 1600 — Ku70; Chain: A; domain 4 |
| Homologous superfamily homologous superfamily | 10 — |