Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | Heparin-binding growth factor 1 × 1 （P05230） | Consistent with protein count |
| UniProt name | SYT1_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–128； UniProt 141–268 |
Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | Synaptotagmin-1 × 1 （P21579） | Consistent with protein count |
| UniProt name | FGF1_HUMAN |
| Isoform | — |
| PDB entities | 2 |
| Chains and sequence ranges | Author chain B； PDBConstruct 1–133； UniProt 23–155 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 2k4a |
| Deposition date deposition_date | 2008-06-02 |
| Structure title title | FGF-1-C2A binary complex structure: a key component in the fibroblast growthfactor non-classical pathway |
| Keywords keywords | ;beta barrel, FGF1-C2A binary complex, Calcium, Cell junction, Cytoplasmic vesicle, Glycoprotein, Lipoprotein, Membrane, Metal-binding, Palmitate, Phosphoprotein, Synapse, Transmembrane, Acetylation, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, Polymorphism, PROTEIN TRANSPORT ;; PROTEIN TRANSPORT |
| Experimental Method method | SOLUTION NMR |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 9 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 20.58 Å |
| Rg (electron density) | 19.66 Å |
| Total Rg | 20.48 Å |
| Atom count | 4201 |
| Residues | 261 |
| Excluded volume | 37581 ų |
| Maximum q | 0.500 Å⁻¹ |
| Assembly | Model | Structure unit | Oligomeric description | Status | CRYSOL | Actions |
|---|---|---|---|---|---|---|
| 1 | 1 | 2k4a__assembly_1__model_1 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 2 | 2k4a__assembly_1__model_2 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 3 | 2k4a__assembly_1__model_3 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 4 | 2k4a__assembly_1__model_4 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 5 | 2k4a__assembly_1__model_5 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 6 | 2k4a__assembly_1__model_6 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 7 | 2k4a__assembly_1__model_7 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 8 | 2k4a__assembly_1__model_8 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 9 | 2k4a__assembly_1__model_9 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 10 | 2k4a__assembly_1__model_10 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 11 | 2k4a__assembly_1__model_11 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 12 | 2k4a__assembly_1__model_12 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 13 | 2k4a__assembly_1__model_13 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 14 | 2k4a__assembly_1__model_14 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 15 | 2k4a__assembly_1__model_15 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 16 | 2k4a__assembly_1__model_16 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 17 | 2k4a__assembly_1__model_17 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 18 | 2k4a__assembly_1__model_18 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 19 | 2k4a__assembly_1__model_19 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 20 | 2k4a__assembly_1__model_20 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| Domain ID domain_id | d2k4aa_ |
| Class class | b — All beta proteins |
| Fold Fold fold | b.7 — C2 domain-like |
| Superfamily Superfamily superfamily | b.7.1 — C2 domain (Calcium/lipid-binding domain, CaLB) |
| Family Family family | b.7.1.2 — Synaptotagmin-like (S variant) |
| Domain ID domain_id | d2k4ab_ |
| Class class | b — All beta proteins |
| Fold Fold fold | b.42 — beta-Trefoil |
| Superfamily Superfamily superfamily | b.42.1 — Cytokine |
| Family Family family | b.42.1.1 — Fibroblast growth factors (FGF) |
| Domain ID domain_id | 2k4aA00 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 40 — Immunoglobulin-like |
| Homologous superfamily homologous superfamily | 150 — C2 domain |
| Domain ID domain_id | 2k4aB00 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 80 — Trefoil |
| Topology topology | 10 — Trefoil (Acidic Fibroblast Growth Factor, subunit A) |
| Homologous superfamily homologous superfamily | 50 — |