SAXSdb — 1e0o

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1. Structure Basics

entry_id	1e0o
deposition_date	2000-04-03
title	CRYSTAL STRUCTURE OF A TERNARY FGF1-FGFR2-HEPARIN COMPLEX
keywords	GROWTH FACTOR, RECEPTOR TYROSINE KINASE, HEPARIN, TERNARY COMPLEX, SIGNAL TRANSDUCTION; GROWTH FACTOR
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	32.80 Å
rg_electron	33.05 Å
i0	97833900.00
molecular_weight	74562.0 kDa
excluded_volume	91433 Å³
envelope_volume	124830 Å³
shell_volume	32067 Å³
envelope_diameter	111.9 Å
shell_rg	38.79 Å
envelope_rg	32.85 Å
shape_rg	33.13 Å
total_rg	33.24 Å
total_atoms	5206
n_residues	652
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	106.3 Å
rg_real	32.84 Å
rg_real_error	0.75 Å
i0_real	9.7830e+07
i0_real_error	1.6120e+06
rg_reciprocal	32.83 Å
i0_reciprocal	97830000.0000
total_estimate	0.8977
solution_quality	GOOD a GOOD solution
n_peaks	0
r_peak_primary	— Å
skewness	0.276
kurtosis	-0.516
angular_range	— – 0.2400 Å⁻¹
current_alpha	0.0001
highest_alpha	8746000.0000
n_real_points	49
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.945; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.955; Smooth: 0.877

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4. Crystallography & Experiment

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5. Entities & Polymer Info (6)

Entity 1 polymer

description	FIBROBLAST GROWTH FACTOR 1
formula_weight	15857.9 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	A,C
atom_count	5247

FNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD

Source

organism	HOMO SAPIENS
common_name	HUMAN
ncbi_taxonomy_id	9606
host_organism	Escherichia coli BL21(DE3)

Entity 2 polymer

description	FIBROBLAST GROWTH FACTOR RECEPTOR 2
formula_weight	24526.8 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	B,D

SNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGRE

Source

organism	HOMO SAPIENS
common_name	HUMAN
ncbi_taxonomy_id	9606
host_organism	Escherichia coli BL21(DE3)

Entity 3 branched

description	;2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose ;
formula_weight	2905.4 kDa
src_method	man
entity_count	1

Entity 4 non-polymer

description	NICKEL (II) ION
formula_weight	58.7 kDa
src_method	syn
entity_count	5

Entity 5 non-polymer

description	SULFATE ION
formula_weight	96.1 kDa
src_method	syn
entity_count	5

Entity 6 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	41

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6. Citations (1)

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length_a	195.900 Å
length_b	195.900 Å
length_c	68.860 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	120.00 °
z_pdb	12

space_group	P 62
int_tables_number	171
crystal_system	—

resolution	2.800 Å
resolution_low	24.200 Å
r_factor	0.2740
r_work	0.2740
r_free	0.3090

fit	/app/data/saxs_computation/e0/1e0o/1e0o.fit
pddf	/app/data/pr_computation/e0/1e0o/1e0o.pr.out
profile	/app/data/saxs_computation/e0/1e0o/1e0o.dat

CRYSTAL STRUCTURE OF A TERNARY FGF1-FGFR2-HEPARIN COMPLEX

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (6)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 branched

Entity 4 non-polymer

Entity 5 non-polymer

Entity 6 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)