Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein homooligomer | Homooligomer | Protein 2 | water × 2 | Consistent with protein count |
| UniProt name | TM173_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 25–265； UniProt 139–379 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 4ef5 |
| Deposition date deposition_date | 2012-03-29 |
| Structure title title | Crystal structure of STING CTD |
| Keywords keywords | ;STING/MITA/ERIS/MPYS/TMEM173, innate immune system, type I interferon, dimerization, c-di-GMP, 5 helices and 5 strands in single domain, IMMUNE SYSTEM ;; IMMUNE SYSTEM |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 25.13 Å |
| Rg (electron density) | 23.79 Å |
| Total Rg | 24.66 Å |
| Atom count | 2866 |
| Residues | 354 |
| Excluded volume | 50768 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d4ef5a_ |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.387 — STING C-terminal-like |
| Superfamily Superfamily superfamily | d.387.1 — STING, TM173 CTD-like |
| Family Family family | d.387.1.1 — Tyrosinase cofactor MelC1 |
| Domain ID domain_id | 4ef5A01 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
| Homologous superfamily homologous superfamily | 5200 — |
| Domain ID domain_id | 4ef5A02 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| Topology topology | 50 — Rossmann fold |
| Homologous superfamily homologous superfamily | 12100 — Stimulator of interferon genes protein |