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6swh

Crystal structure of the ternary complex between the type 1 pilus proteins FimC, FimI and FimA from E. coli

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Chaperone protein FimC

Escherichia coli (strain K12)

UniProt P31697

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 Fimbrin-like protein FimI × 1 （P39264） Type-1 fimbrial protein, A chain × 1 （P04128） DI(HYDROXYETHYL)ETHER × 1 1,2-ETHANEDIOL × 1 water × 3 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 Fimbrin-like protein FimI × 1 （P39264） Type-1 fimbrial protein, A chain × 1 （P04128） water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1bf8

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1kiu 1kiu 1kiu 1kiu 1kiu 1kiu 1kiu 1kiu 1kiu 1kiu 1kiu 1klf

56 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name FIMC_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–205； UniProt 37–241 Author chain D； PDBConstruct 1–205； UniProt 37–241

Fimbrin-like protein FimI

Escherichia coli (strain K12)

UniProt P39264

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 Chaperone protein FimC × 1 （P31697） Type-1 fimbrial protein, A chain × 1 （P04128） DI(HYDROXYETHYL)ETHER × 1 1,2-ETHANEDIOL × 1 water × 3 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 Chaperone protein FimC × 1 （P31697） Type-1 fimbrial protein, A chain × 1 （P04128） water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6swh 6swh 7b0w 7b0x 9fx8 9fxb 9fxs

7 assemblies

View Construct and Data Evidence
UniProt name FIMI_ECOLI
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–160； UniProt 20–179 Author chain E； PDBConstruct 1–160； UniProt 20–179

Type-1 fimbrial protein, A chain

Escherichia coli (strain K12)

UniProt P04128

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 Chaperone protein FimC × 1 （P31697） Fimbrin-like protein FimI × 1 （P39264） DI(HYDROXYETHYL)ETHER × 1 1,2-ETHANEDIOL × 1 water × 3 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 Chaperone protein FimC × 1 （P31697） Fimbrin-like protein FimI × 1 （P39264） water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2jty 2m5g 5nkt 6r74

4 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
5oh0 6c53 6y7s 8psv 8ptu 9ftt 9fxa 9vkv 9x67

9 assemblies

Heteromeric or nucleic-acid complex
3sqb 3sqb 3sqb 3sqb 4dwh 4dwh 6swh 6swh 9fw9 9fwb 9fwz 9fx0

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name FIMA1_ECOLI
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 8–153； UniProt 37–182 Author chain F； PDBConstruct 8–153； UniProt 37–182

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6swh
Deposition date deposition_date2019-09-20
Structure title titleCrystal structure of the ternary complex between the type 1 pilus proteins FimC, FimI and FimA from E. coli
Keywords keywordsstructural protein, structural protein complex, pilus assembly inhibition; STRUCTURAL PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6swh__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6swh__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6swh__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）26.45 Å
Rg (electron density)25.76 Å
Total Rg26.38 Å
Atom count3498
Residues464
Excluded volume62105 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6swh__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6swh__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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6. Fold Classification (SCOP + CATH) 11 domains

SCOP 2.08 (8 domains)

Domain ID domain_idd6swha1
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.11 — PapD-like
Family Family familyb.1.11.1 — Pilus chaperone
Domain ID domain_idd6swha2
Class classb — All beta proteins
Fold Fold foldb.7 — C2 domain-like
Superfamily Superfamily superfamilyb.7.2 — Periplasmic chaperone C-domain
Family Family familyb.7.2.1 — Periplasmic chaperone C-domain
Domain ID domain_idd6swhb_
Class classb — All beta proteins
Fold Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily Superfamily superfamilyb.2.3 — Bacterial adhesins
Family Family familyb.2.3.0 — automated matches
Domain ID domain_idd6swhc_
Class classb — All beta proteins
Fold Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily Superfamily superfamilyb.2.3 — Bacterial adhesins
Family Family familyb.2.3.0 — automated matches
Domain ID domain_idd6swhd1
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.11 — PapD-like
Family Family familyb.1.11.1 — Pilus chaperone
Domain ID domain_idd6swhd2
Class classb — All beta proteins
Fold Fold foldb.7 — C2 domain-like
Superfamily Superfamily superfamilyb.7.2 — Periplasmic chaperone C-domain
Family Family familyb.7.2.1 — Periplasmic chaperone C-domain
Domain ID domain_idd6swhe_
Class classb — All beta proteins
Fold Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily Superfamily superfamilyb.2.3 — Bacterial adhesins
Family Family familyb.2.3.0 — automated matches
Domain ID domain_idd6swhf_
Class classb — All beta proteins
Fold Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily Superfamily superfamilyb.2.3 — Bacterial adhesins
Family Family familyb.2.3.0 — automated matches

CATH v4.4 (3 domains)

Domain ID domain_id6swhB01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily1090 — Fimbrial-type adhesion domain
Domain ID domain_id6swhE01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily1090 — Fimbrial-type adhesion domain
Domain ID domain_id6swhF01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily1090 — Fimbrial-type adhesion domain
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7. Citations (1)