7ml3

General transcription factor TFIIH (weak binding)

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

BJ4_G0050160.mRNA.1.CDS.1

OrganismNot specified

UniProt A0A7I9BTI9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 8 DNA 2 RNA polymerase II transcription factor B subunit 2 × 1 (A0A6A5Q2X3) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (A0A6A5Q1C1) Tfb1 × 1 General transcription and DNA repair factor IIH subunit TFB4 × 1 (A0A7I9C5C2) General transcription and DNA repair factor IIH × 1 (A0A7I9FQL5) General transcription and DNA repair factor IIH subunit TFB5 × 1 (Q3E7C1) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (Q00578) non-template strand DNA × 1 template strand DNA × 1 ZINC ION × 7 IRON/SULFUR CLUSTER × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A7I9BTI9_YEASX
Isoform —
PDB entities 1
Chains and sequence ranges Author chain 3; PDBConstruct 1–321; UniProt 1–321

RNA polymerase II transcription factor B subunit 2

OrganismNot specified

UniProt A0A6A5Q2X3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 8 DNA 2 BJ4_G0050160.mRNA.1.CDS.1 × 1 (A0A7I9BTI9) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (A0A6A5Q1C1) Tfb1 × 1 General transcription and DNA repair factor IIH subunit TFB4 × 1 (A0A7I9C5C2) General transcription and DNA repair factor IIH × 1 (A0A7I9FQL5) General transcription and DNA repair factor IIH subunit TFB5 × 1 (Q3E7C1) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (Q00578) non-template strand DNA × 1 template strand DNA × 1 ZINC ION × 7 IRON/SULFUR CLUSTER × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A6A5Q2X3_YEASX
Isoform —
PDB entities 2
Chains and sequence ranges Author chain 2; PDBConstruct 1–513; UniProt 1–513

General transcription and DNA repair factor IIH helicase subunit XPD

OrganismNot specified

UniProt A0A6A5Q1C1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 8 DNA 2 BJ4_G0050160.mRNA.1.CDS.1 × 1 (A0A7I9BTI9) RNA polymerase II transcription factor B subunit 2 × 1 (A0A6A5Q2X3) Tfb1 × 1 General transcription and DNA repair factor IIH subunit TFB4 × 1 (A0A7I9C5C2) General transcription and DNA repair factor IIH × 1 (A0A7I9FQL5) General transcription and DNA repair factor IIH subunit TFB5 × 1 (Q3E7C1) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (Q00578) non-template strand DNA × 1 template strand DNA × 1 ZINC ION × 7 IRON/SULFUR CLUSTER × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A6A5Q1C1_YEASX
Isoform —
PDB entities 3
Chains and sequence ranges Author chain 0; PDBConstruct 1–778; UniProt 1–778

General transcription and DNA repair factor IIH subunit TFB4

OrganismNot specified

UniProt A0A7I9C5C2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 8 DNA 2 BJ4_G0050160.mRNA.1.CDS.1 × 1 (A0A7I9BTI9) RNA polymerase II transcription factor B subunit 2 × 1 (A0A6A5Q2X3) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (A0A6A5Q1C1) Tfb1 × 1 General transcription and DNA repair factor IIH × 1 (A0A7I9FQL5) General transcription and DNA repair factor IIH subunit TFB5 × 1 (Q3E7C1) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (Q00578) non-template strand DNA × 1 template strand DNA × 1 ZINC ION × 7 IRON/SULFUR CLUSTER × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A7I9C5C2_YEASX
Isoform —
PDB entities 5
Chains and sequence ranges Author chain 4; PDBConstruct 1–338; UniProt 1–338

General transcription and DNA repair factor IIH

OrganismNot specified

UniProt A0A7I9FQL5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 8 DNA 2 BJ4_G0050160.mRNA.1.CDS.1 × 1 (A0A7I9BTI9) RNA polymerase II transcription factor B subunit 2 × 1 (A0A6A5Q2X3) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (A0A6A5Q1C1) Tfb1 × 1 General transcription and DNA repair factor IIH subunit TFB4 × 1 (A0A7I9C5C2) General transcription and DNA repair factor IIH subunit TFB5 × 1 (Q3E7C1) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (Q00578) non-template strand DNA × 1 template strand DNA × 1 ZINC ION × 7 IRON/SULFUR CLUSTER × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A7I9FQL5_YEASX
Isoform —
PDB entities 6
Chains and sequence ranges Author chain 6; PDBConstruct 1–461; UniProt 1–461

General transcription and DNA repair factor IIH subunit TFB5

OrganismNot specified

UniProt Q3E7C1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 8 DNA 2 BJ4_G0050160.mRNA.1.CDS.1 × 1 (A0A7I9BTI9) RNA polymerase II transcription factor B subunit 2 × 1 (A0A6A5Q2X3) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (A0A6A5Q1C1) Tfb1 × 1 General transcription and DNA repair factor IIH subunit TFB4 × 1 (A0A7I9C5C2) General transcription and DNA repair factor IIH × 1 (A0A7I9FQL5) General transcription and DNA repair factor IIH helicase subunit XPB × 1 (Q00578) non-template strand DNA × 1 template strand DNA × 1 ZINC ION × 7 IRON/SULFUR CLUSTER × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name TFB5_YEAST
Isoform —
PDB entities 7
Chains and sequence ranges Author chain 5; PDBConstruct 1–72; UniProt 1–72

General transcription and DNA repair factor IIH helicase subunit XPB

OrganismNot specified

UniProt Q00578

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 8 DNA 2 BJ4_G0050160.mRNA.1.CDS.1 × 1 (A0A7I9BTI9) RNA polymerase II transcription factor B subunit 2 × 1 (A0A6A5Q2X3) General transcription and DNA repair factor IIH helicase subunit XPD × 1 (A0A6A5Q1C1) Tfb1 × 1 General transcription and DNA repair factor IIH subunit TFB4 × 1 (A0A7I9C5C2) General transcription and DNA repair factor IIH × 1 (A0A7I9FQL5) General transcription and DNA repair factor IIH subunit TFB5 × 1 (Q3E7C1) non-template strand DNA × 1 template strand DNA × 1 ZINC ION × 7 IRON/SULFUR CLUSTER × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RAD25_YEAST
Isoform —
PDB entities 8
Chains and sequence ranges Author chain 7; PDBConstruct 1–843; UniProt 1–843

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7ml3
Deposition date deposition_date2021-04-27
Structure title titleGeneral transcription factor TFIIH (weak binding)
Keywords keywordsPIC, TFIIH, transcription, ITC, RNA polymerase II; TRANSCRIPTION
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7ml3__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7ml3__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7ml3__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)54.75 Å
Rg (electron density)53.73 Å
Total Rg53.83 Å
Atom count22648
Residues3028
Excluded volume395790 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7ml3__assembly_1__model_1 decameric (10) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (12)

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7. Citations (1)