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8aza

Structure of RIP2K dimer bound to the XIAP BIR2 domain

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

E3 ubiquitin-protein ligase XIAP

Homo sapiens

UniProt P98170

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 Receptor-interacting serine/threonine-protein kinase 2 × 2 （O43353） ZINC ION × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1c9q 1f9x 1tfq 1tft 2ecg 2jk7 2kna 3clx 3clx 3clx 3clx 3cm2

81 assemblies; showing the first 12

Homodimer
2opy 2poi 2qra 2qra 3clx 3clx 3cm2 3cm2 3cm2 3cm2 3cm2 3cm7

35 assemblies; showing the first 12

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1g3f 1g73 1g73 1i3o 1i4o 1i4o 1i4o 1i51 1kmc 1nw9 2opz 2opz

29 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name XIAP_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain C； PDBConstruct 1–87； UniProt 154–240

Receptor-interacting serine/threonine-protein kinase 2

Homo sapiens

UniProt O43353

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 E3 ubiquitin-protein ligase XIAP × 1 （P98170） ZINC ION × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2n7z 5ng3 5ng3 5ng3 5ng3 6es0 6es0 6ul8 6ul8

9 assemblies

Homodimer
4c8b 5ar2 5ar3 5ar4 5ar5 5ar7 5ar8 5j79 5j7b 5ng0 5ng2 5w5j

30 assemblies; showing the first 12

Homotetramer

None

Other homooligomers
5yrn 6ggs

2 assemblies

Heteromeric or nucleic-acid complex
2n83 6gfj 7obs 7obt 8aza

5 assemblies

View Construct and Data Evidence
UniProt name RIPK2_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain A； PDBConstruct 1–317； UniProt 1–317 Author chain B； PDBConstruct 1–317； UniProt 1–317

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8aza
Deposition date deposition_date2022-09-05
Structure title titleStructure of RIP2K dimer bound to the XIAP BIR2 domain
Keywords keywordskinase, BIR2, complex, dimer, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8aza__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8aza__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8aza__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）27.38 Å
Rg (electron density)26.32 Å
Total Rg27.15 Å
Atom count4970
Residues606
Excluded volume88987 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8aza__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)