← Back to search
8c3h

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex a long aspartimide degron peptide

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Cereblon isoform 4

Magnetospirillum gryphiswaldense

UniProt A4TVL0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 P3(40) × 1 （P05067） ZINC ION × 1 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 P3(40) × 1 （P05067） ZINC ION × 1 water × 2 Consistent with protein count
3 Protein monomer Monomer Protein 1 ZINC ION × 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
4v2y 4v2y 4v2y 4v2z 4v2z 4v2z 4v30 4v30 4v30 4v31 4v31 4v31

158 assemblies; showing the first 12

Homodimer

None

Homotetramer

None

Other homooligomers
8ou3 8ou5 8ou6 8ou9 8oua

5 assemblies

Heteromeric or nucleic-acid complex
6r0q 6r0q 6r0s 6r12 6r18 8bc6 8bc6 8bc7 8c3h 8c3h

10 assemblies

View Construct and Data Evidence
UniProt name A4TVL0_9PROT
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–124； UniProt 1–124 Author chain B； PDBConstruct 1–124； UniProt 1–124 Author chain C； PDBConstruct 1–124； UniProt 1–124

P3(40)

OrganismNot specified

UniProt P05067

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Cereblon isoform 4 × 1 （A4TVL0） ZINC ION × 1 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Cereblon isoform 4 × 1 （A4TVL0） ZINC ION × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1amb 1amc 1aml 1ba4 1ba6 1bjb 1bjc 1hz3 1iyt 1mwp 1owt 1qcm

64 assemblies; showing the first 12

Homodimer
1aap 2loh 2lz3 2lz4 2mgt 2y3k 2y3k 2y3k 2y3k 3ktm 3ktm 3ktm

18 assemblies; showing the first 12

Homotetramer
2y3j 2y3j 2y3l 3ovj 6rhy 6wxm 6wxm

7 assemblies

Other homooligomers
11en 11eo 11ep 12gb 21fb 2beg 2lmn 2lmo 2lmp 2lmq 2lnq 2m4j

99 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
1brc 1ca0 1ca0 1taw 1x11 1x11 1x11 1zjd 2otk 2r0w 2wk3 2wk3

95 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name A4_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain D； PDBConstruct 1–8； UniProt 763–770 Author chain E； PDBConstruct 1–8； UniProt 763–770

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id8c3h
Deposition date deposition_date2022-12-23
Structure title titleCereblon isoform 4 from Magnetospirillum gryphiswaldense in complex a long aspartimide degron peptide
Keywords keywordsProtein Damage, Protein Ageing, Protein Chain Break, Aspartimide, SIGNALING PROTEIN; SIGNALING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8c3h__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8c3h__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8c3h__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）14.21 Å
Rg (electron density)12.77 Å
Total Rg14.12 Å
Atom count856
Residues110
Excluded volume15051 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8c3h__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 8c3h__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 8c3h__assembly_3__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (4)

▶

7. Citations (1)